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The map label for this gene is arnB

Identifier: 153948959

GI number: 153948959

Start: 1992107

End: 1993261

Strand: Direct

Name: arnB

Synonym: YpsIP31758_1723

Alternate gene names: 153948959

Gene position: 1992107-1993261 (Clockwise)

Preceding gene: 153950434

Following gene: 153947753

Centisome position: 42.18

GC content: 48.31

Gene sequence:

>1155_bases
ATGCAGAGTTTTTTGCCTTTTTCTAGGCCAGCAATAGGTAGTGAAGAAATTAATGCTGTTGCTAATGTATTAGGCTCTGG
TTGGATTACTACCGGTCCCCAGAATCATCAATTGGAAACTGATTTCTGTCAAATTTTTGGTTGCAAACATGCGATCGCTG
TATGTTCTGCAACAGCAGGAATGCACATTACATTGCTGGCGTTGGGCATTGGCCCTGGTGATGAGGTTATTACGCCATCA
CAGACGTGGGTTTCTACGATTAACATGATCGTGTTGCTGGGTGCAGAACCCGTAATGGTCGATGTTGATCGCGATACCTT
GATGGTAAATGCGGCTGCTATTGAAGCGGCGATTACACCGAACACCAAAGCCATTATTCCCGTCCACTATGCTGGCGCGC
CCTGCGACCTTGATGCATTGCGTCAGATCTCCCAACGGCATGGTATCCCACTGATTGAAGATGCTGCACATGCCGTTGGC
ACTCGTTATCGAGATCAATGGATTGGTGAGCAGGGGACCGCTATTTTCTCTTTCCATGCCATCAAGAATATCACTTGTGC
TGAGGGGGGATTAGTTGCCACCGATGATGATGAATTGGCGGCCAGAGTCCGTCGGCTTAAGTTCCATGGCCTGGGTGTGG
ATGCCTTTGACCGACAAATACAGGGGCGTAGCCCACAGGCTGAAGTTGTGGAACCGGGGTATAAATATAACTTATCTGAT
ATCCACGCCGCTATTGCGGTGGTGCAGCTTAGACGTTTGCCCGAAATTAACGCCCGTCGGCAGGCGCTGGTTGCTTCCTA
TCATAAGGCATTAGCGCATTTGCCTTTGCAGCCGTTGGCCTTGCCTCACTATTCTCATCAACATGCCTGGCACCTTTTCA
TGGTGCGTGTTGATGAAGAACGCTGTGGTATTAGCCGGGATCAACTGATGGCGTGTTTGAAAGATATGGGTATTGGCAGT
GGGCTACATTTTCGTGCGGTACATAGCCAAAAATATTATCGCGAACGTTATCCGCATTTGTGTTTGCCCAACACGGAATG
GAACTCAGCCAGATTGTGCACGTTACCGCTTTTCCCCGATATGCTAGACAGTGATATTGAACGAGTGGCTAATGCATTAA
CAACAATTATAGGGTCACACCGTGTCACTAAATGA

Upstream 100 bases:

>100_bases
CCATAGCAGGTGACGCTCTTATCTGATTGGCGTTTAGTTTTCGTTAACTTATCTGGGCATATAGTTAATAGTCCATGAAG
GTGTCCTAAGGGATTTATTA

Downstream 100 bases:

>100_bases
ACCAATTAAGAAGGTCTCCATTGTTATTCCTGTCTATAACGAGCAAGAGAGCTTGCCAGCATTAATAGACAGAACGACGG
CTGCCTGTAAATTACTTACA

Product: UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase

Products: NA

Alternate protein names: UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase; UDP-Ara4O aminotransferase; UDP-4-amino-4-deoxy-L-arabinose aminotransferase

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MQSFLPFSRPAIGSEEINAVANVLGSGWITTGPQNHQLETDFCQIFGCKHAIAVCSATAGMHITLLALGIGPGDEVITPS
QTWVSTINMIVLLGAEPVMVDVDRDTLMVNAAAIEAAITPNTKAIIPVHYAGAPCDLDALRQISQRHGIPLIEDAAHAVG
TRYRDQWIGEQGTAIFSFHAIKNITCAEGGLVATDDDELAARVRRLKFHGLGVDAFDRQIQGRSPQAEVVEPGYKYNLSD
IHAAIAVVQLRRLPEINARRQALVASYHKALAHLPLQPLALPHYSHQHAWHLFMVRVDEERCGISRDQLMACLKDMGIGS
GLHFRAVHSQKYYRERYPHLCLPNTEWNSARLCTLPLFPDMLDSDIERVANALTTIIGSHRVTK

Sequences:

>Translated_384_residues
MQSFLPFSRPAIGSEEINAVANVLGSGWITTGPQNHQLETDFCQIFGCKHAIAVCSATAGMHITLLALGIGPGDEVITPS
QTWVSTINMIVLLGAEPVMVDVDRDTLMVNAAAIEAAITPNTKAIIPVHYAGAPCDLDALRQISQRHGIPLIEDAAHAVG
TRYRDQWIGEQGTAIFSFHAIKNITCAEGGLVATDDDELAARVRRLKFHGLGVDAFDRQIQGRSPQAEVVEPGYKYNLSD
IHAAIAVVQLRRLPEINARRQALVASYHKALAHLPLQPLALPHYSHQHAWHLFMVRVDEERCGISRDQLMACLKDMGIGS
GLHFRAVHSQKYYRERYPHLCLPNTEWNSARLCTLPLFPDMLDSDIERVANALTTIIGSHRVTK
>Mature_384_residues
MQSFLPFSRPAIGSEEINAVANVLGSGWITTGPQNHQLETDFCQIFGCKHAIAVCSATAGMHITLLALGIGPGDEVITPS
QTWVSTINMIVLLGAEPVMVDVDRDTLMVNAAAIEAAITPNTKAIIPVHYAGAPCDLDALRQISQRHGIPLIEDAAHAVG
TRYRDQWIGEQGTAIFSFHAIKNITCAEGGLVATDDDELAARVRRLKFHGLGVDAFDRQIQGRSPQAEVVEPGYKYNLSD
IHAAIAVVQLRRLPEINARRQALVASYHKALAHLPLQPLALPHYSHQHAWHLFMVRVDEERCGISRDQLMACLKDMGIGS
GLHFRAVHSQKYYRERYPHLCLPNTEWNSARLCTLPLFPDMLDSDIERVANALTTIIGSHRVTK

Specific function: Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family. ArnB subfamily

Homologues:

Organism=Escherichia coli, GI145693159, Length=378, Percent_Identity=69.3121693121693, Blast_Score=543, Evalue=1e-156,
Organism=Escherichia coli, GI2367285, Length=373, Percent_Identity=32.9758713136729, Blast_Score=171, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARNB_YERP3 (A7FHH2)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001400700.1
- ProteinModelPortal:   A7FHH2
- SMR:   A7FHH2
- STRING:   A7FHH2
- GeneID:   5388237
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_1723
- eggNOG:   COG0399
- HOGENOM:   HBG660897
- OMA:   NVTCAEG
- ProtClustDB:   PRK11658
- BioCyc:   YPSE349747:YPSIP31758_1723-MONOMER
- HAMAP:   MF_01167
- InterPro:   IPR022850
- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PIRSF:   PIRSF000390

Pfam domain/function: PF01041 DegT_DnrJ_EryC1; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.87

Molecular weight: Translated: 42247; Mature: 42247

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSFLPFSRPAIGSEEINAVANVLGSGWITTGPQNHQLETDFCQIFGCKHAIAVCSATAG
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
MHITLLALGIGPGDEVITPSQTWVSTINMIVLLGAEPVMVDVDRDTLMVNAAAIEAAITP
CEEEEEEEECCCCCCCCCCCHHHHHHHHEEEEECCCCEEEECCCCEEEEEHHHEEEEECC
NTKAIIPVHYAGAPCDLDALRQISQRHGIPLIEDAAHAVGTRYRDQWIGEQGTAIFSFHA
CCCEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEHH
IKNITCAEGGLVATDDDELAARVRRLKFHGLGVDAFDRQIQGRSPQAEVVEPGYKYNLSD
HCCCEECCCCEEECCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHCCCCCCCCHHH
IHAAIAVVQLRRLPEINARRQALVASYHKALAHLPLQPLALPHYSHQHAWHLFMVRVDEE
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECHH
RCGISRDQLMACLKDMGIGSGLHFRAVHSQKYYRERYPHLCLPNTEWNSARLCTLPLFPD
HHCCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCCCEECCCCCCCCEEEEEECCCHH
MLDSDIERVANALTTIIGSHRVTK
HHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQSFLPFSRPAIGSEEINAVANVLGSGWITTGPQNHQLETDFCQIFGCKHAIAVCSATAG
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
MHITLLALGIGPGDEVITPSQTWVSTINMIVLLGAEPVMVDVDRDTLMVNAAAIEAAITP
CEEEEEEEECCCCCCCCCCCHHHHHHHHEEEEECCCCEEEECCCCEEEEEHHHEEEEECC
NTKAIIPVHYAGAPCDLDALRQISQRHGIPLIEDAAHAVGTRYRDQWIGEQGTAIFSFHA
CCCEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEHH
IKNITCAEGGLVATDDDELAARVRRLKFHGLGVDAFDRQIQGRSPQAEVVEPGYKYNLSD
HCCCEECCCCEEECCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHCCCCCCCCHHH
IHAAIAVVQLRRLPEINARRQALVASYHKALAHLPLQPLALPHYSHQHAWHLFMVRVDEE
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECHH
RCGISRDQLMACLKDMGIGSGLHFRAVHSQKYYRERYPHLCLPNTEWNSARLCTLPLFPD
HHCCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCCCEECCCCCCCCEEEEEECCCHH
MLDSDIERVANALTTIIGSHRVTK
HHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA