BacMap

Definition	Yersinia pseudotuberculosis IP 31758, complete genome.
Accession	NC_009708
Length	4,723,306

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The map label for this gene is btuD

Identifier: 153950434

GI number: 153950434

Start: 1990999

End: 1991757

Strand: Direct

Name: btuD

Synonym: YpsIP31758_1722

Alternate gene names: 153950434

Gene position: 1990999-1991757 (Clockwise)

Preceding gene: 153949548

Following gene: 153948959

Centisome position: 42.15

GC content: 46.77

Gene sequence:

>759_bases
ATGCTATTGCAACTCAACAATGTCAGCGTAGGAACCCGCCTTGCTTCTTTTTCTTCGCAGGTGACCACGGGGTTGCAAAT
TCATTTGATTGGCCCGAATGGGGCAGGGAAAAGCACTTTGCTGGCCTCGTTGGCGGGGTTATTGCCTGCTAGCGGCGAAA
TTGTGTTAGCGGGTAAATCATTGCAACACTATGAAGGGCATGAATTAGCCCGTCAACGGGCCTATTTATCTCAGCAGCAG
TCCGCATTGTCCCTGATGCCTGTTTTCCAGTATCTTTCTCTTTATCAACCCGCCGGTGCTAATTCACAGGCTGTGGCAAC
AGCGATTAGCTATATCTGTAATAAGCTGCGTTTAACCGACAAATTACCGCGAATGCTGTCACATCTTTCAGGTGGTGAAT
GGCAACGCGTGCGGTTAGCTGCGGTATTTTTGCAAGTTTGGCCGGATATCAACCCTGACAGTAAATTATTGTTGCTGGAT
GAACCCTATAGTGGCCTAGATGTTGCCCAGAAAGTGGCTTTAGATGCTTTATTAGTGGAATTTTGTCGGTCAGGGCGCAG
TGTTATCATCAGTGGCCATGACCTCAACCATACGTTACAGCAAGCTGACGAAGTATGGTTGCTGGCTCAAGGGCAAGTAT
TAGTGCAAGGAGAAACCCAGCAAGTCATGCGAGCGGATGTGCTCTCCCAAGTATTTGAAGTTGATTTTCAAATACACAAT
TTTAATAAACAGCAGTGGATTACCACAAGAAGCGTATAA

Upstream 100 bases:

>100_bases
GCGTTTTGCTCCAGATATGGCACCAGAAGCACCTATTTTAATCAATGCCATCAATCAGGCACTGGCTAGCCACTAAATTA
CGGGTAACGAGTTTATTTTG

Downstream 100 bases:

>100_bases
CGCTTAGATATATTTATTGGCAATAAAATATTATTTACTTCTCCTATTCTCATCAGATCATTGTGCTTACGATGTTATTT
TATCGTGGACATTATCAGTA

Product: vitamin B12-transporter ATPase

Products: NA

Alternate protein names: Vitamin B12-transporting ATPase

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MLLQLNNVSVGTRLASFSSQVTTGLQIHLIGPNGAGKSTLLASLAGLLPASGEIVLAGKSLQHYEGHELARQRAYLSQQQ
SALSLMPVFQYLSLYQPAGANSQAVATAISYICNKLRLTDKLPRMLSHLSGGEWQRVRLAAVFLQVWPDINPDSKLLLLD
EPYSGLDVAQKVALDALLVEFCRSGRSVIISGHDLNHTLQQADEVWLLAQGQVLVQGETQQVMRADVLSQVFEVDFQIHN
FNKQQWITTRSV

Sequences:

>Translated_252_residues
MLLQLNNVSVGTRLASFSSQVTTGLQIHLIGPNGAGKSTLLASLAGLLPASGEIVLAGKSLQHYEGHELARQRAYLSQQQ
SALSLMPVFQYLSLYQPAGANSQAVATAISYICNKLRLTDKLPRMLSHLSGGEWQRVRLAAVFLQVWPDINPDSKLLLLD
EPYSGLDVAQKVALDALLVEFCRSGRSVIISGHDLNHTLQQADEVWLLAQGQVLVQGETQQVMRADVLSQVFEVDFQIHN
FNKQQWITTRSV
>Mature_252_residues
MLLQLNNVSVGTRLASFSSQVTTGLQIHLIGPNGAGKSTLLASLAGLLPASGEIVLAGKSLQHYEGHELARQRAYLSQQQ
SALSLMPVFQYLSLYQPAGANSQAVATAISYICNKLRLTDKLPRMLSHLSGGEWQRVRLAAVFLQVWPDINPDSKLLLLD
EPYSGLDVAQKVALDALLVEFCRSGRSVIISGHDLNHTLQQADEVWLLAQGQVLVQGETQQVMRADVLSQVFEVDFQIHN
FNKQQWITTRSV

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system

COG id: COG4138

COG function: function code H; ABC-type cobalamin transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain

Homologues:

Organism=Homo sapiens, GI105990541, Length=204, Percent_Identity=27.9411764705882, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI31657092, Length=211, Percent_Identity=29.3838862559242, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI11967969, Length=223, Percent_Identity=26.9058295964126, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI30795238, Length=225, Percent_Identity=25.3333333333333, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI21536376, Length=212, Percent_Identity=25.4716981132075, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI171184400, Length=227, Percent_Identity=29.5154185022026, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI27262624, Length=216, Percent_Identity=27.3148148148148, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI27262626, Length=216, Percent_Identity=27.3148148148148, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI9665248, Length=203, Percent_Identity=33.0049261083744, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI150417984, Length=193, Percent_Identity=28.4974093264249, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI27881501, Length=225, Percent_Identity=25.3333333333333, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1788002, Length=237, Percent_Identity=45.5696202531646, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI1790739, Length=243, Percent_Identity=34.156378600823, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1786345, Length=230, Percent_Identity=33.0434782608696, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1786803, Length=233, Percent_Identity=28.755364806867, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786253, Length=210, Percent_Identity=30.952380952381, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789593, Length=225, Percent_Identity=25.7777777777778, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1789873, Length=192, Percent_Identity=30.7291666666667, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1789864, Length=241, Percent_Identity=26.5560165975104, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788761, Length=228, Percent_Identity=29.3859649122807, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI48994943, Length=220, Percent_Identity=28.1818181818182, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786703, Length=200, Percent_Identity=33.5, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788165, Length=213, Percent_Identity=34.2723004694836, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786563, Length=230, Percent_Identity=30, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788450, Length=193, Percent_Identity=31.0880829015544, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790544, Length=220, Percent_Identity=28.6363636363636, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787029, Length=218, Percent_Identity=27.0642201834862, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790467, Length=188, Percent_Identity=29.2553191489362, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87081782, Length=209, Percent_Identity=28.7081339712919, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789032, Length=229, Percent_Identity=25.3275109170306, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786398, Length=245, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787089, Length=233, Percent_Identity=27.8969957081545, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787143, Length=223, Percent_Identity=26.457399103139, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=220, Percent_Identity=29.0909090909091, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71983510, Length=194, Percent_Identity=26.2886597938144, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71983523, Length=194, Percent_Identity=26.2886597938144, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71983516, Length=194, Percent_Identity=26.2886597938144, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71992285, Length=217, Percent_Identity=25.8064516129032, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71992290, Length=217, Percent_Identity=25.8064516129032, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71984940, Length=208, Percent_Identity=29.3269230769231, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17558664, Length=217, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=187, Percent_Identity=28.8770053475936, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25146777, Length=241, Percent_Identity=26.5560165975104, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI85724858, Length=201, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI85724856, Length=201, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24580547, Length=201, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24580551, Length=201, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24580549, Length=201, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24580545, Length=201, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI161076682, Length=221, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI161076684, Length=221, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24581617, Length=221, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24581615, Length=221, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI116007328, Length=223, Percent_Identity=26.457399103139, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI28574150, Length=223, Percent_Identity=26.457399103139, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24581383, Length=202, Percent_Identity=30.1980198019802, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581385, Length=202, Percent_Identity=30.1980198019802, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581387, Length=202, Percent_Identity=30.1980198019802, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28574533, Length=209, Percent_Identity=28.2296650717703, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21357907, Length=245, Percent_Identity=29.3877551020408, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI85726357, Length=213, Percent_Identity=27.2300469483568, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24666092, Length=199, Percent_Identity=27.1356783919598, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI85816269, Length=227, Percent_Identity=28.6343612334802, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24580553, Length=227, Percent_Identity=28.6343612334802, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI85724864, Length=227, Percent_Identity=28.6343612334802, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24580555, Length=227, Percent_Identity=28.6343612334802, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BTUD_YERPE (Q8ZDX6)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AG0295
- RefSeq:   NP_669232.1
- RefSeq:   NP_993539.1
- RefSeq:   YP_002347386.1
- ProteinModelPortal:   Q8ZDX6
- SMR:   Q8ZDX6
- GeneID:   1146863
- GeneID:   1175256
- GeneID:   2764998
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO2423
- KEGG:   ypk:y1916
- KEGG:   ypm:YP_2210
- HOGENOM:   HBG758042
- OMA:   VWHYLAL
- ProtClustDB:   PRK03695
- BioCyc:   YPES187410:Y1916-MONOMER
- BioCyc:   YPES214092:YPO2423-MONOMER
- BRENDA:   3.6.3.33
- HAMAP:   MF_01005
- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- SMART:   SM00382

Pfam domain/function: PF00005 ABC_tran

EC number: =3.6.3.33

Molecular weight: Translated: 27686; Mature: 27686

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLQLNNVSVGTRLASFSSQVTTGLQIHLIGPNGAGKSTLLASLAGLLPASGEIVLAGKS
CEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEECCC
LQHYEGHELARQRAYLSQQQSALSLMPVFQYLSLYQPAGANSQAVATAISYICNKLRLTD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
KLPRMLSHLSGGEWQRVRLAAVFLQVWPDINPDSKLLLLDEPYSGLDVAQKVALDALLVE
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
FCRSGRSVIISGHDLNHTLQQADEVWLLAQGQVLVQGETQQVMRADVLSQVFEVDFQIHN
HHHCCCEEEEECCCCHHHHHHHCCEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHEEEC
FNKQQWITTRSV
CCCHHEEEECCC
>Mature Secondary Structure
MLLQLNNVSVGTRLASFSSQVTTGLQIHLIGPNGAGKSTLLASLAGLLPASGEIVLAGKS
CEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEECCC
LQHYEGHELARQRAYLSQQQSALSLMPVFQYLSLYQPAGANSQAVATAISYICNKLRLTD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
KLPRMLSHLSGGEWQRVRLAAVFLQVWPDINPDSKLLLLDEPYSGLDVAQKVALDALLVE
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
FCRSGRSVIISGHDLNHTLQQADEVWLLAQGQVLVQGETQQVMRADVLSQVFEVDFQIHN
HHHCCCEEEEECCCCHHHHHHHCCEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHEEEC
FNKQQWITTRSV
CCCHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430