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The map label for this gene is cobO [H]

Identifier: 153948399

GI number: 153948399

Start: 2231990

End: 2232580

Strand: Direct

Name: cobO [H]

Synonym: YpsIP31758_1927

Alternate gene names: 153948399

Gene position: 2231990-2232580 (Clockwise)

Preceding gene: 153946851

Following gene: 153949245

Centisome position: 47.25

GC content: 49.92

Gene sequence:

>591_bases
ATGTCTGAAGATCGCCACCAGCAGCGCCAACAACGATTAAAAGAAAAGGTAGATTCACGGATTGCTGCAGCACAGGAAGT
TCGCGGTATTTTGATCGTGTTTACCGGTAACGGGAAAGGTAAAACTACAGCAGCTTTCGGAACAGTCACCCGCGCGGTGG
GCCATGGCCTTAAAGCGGGGGTCATACAGTTTATCAAGGGGGAGTGGCCAAACGGTGAAAAGAACCTGCTGCAACAACAT
GGCGTTGAATTTCAGGTGATGGCGACCGGTTTTACCTGGAATACACAAGACAGGGAGACGGATACGGTAGCCTGTCTGGG
GGTTTGGCAACATGCTTTACGCATGTTAGCAGACCCAACATTGGATTTAGTGGTATTGGATGAGCTGACCTATATGATCG
CTTACGACTACTTGCCATTGGATGAGGTGATTAACGCACTCAATCAGCGCCCTGCTCATCAAACGGTGATTATTACAGGC
CGCGGGTGCCACCGGGATCTACTGGAGATGGCGGATACCGTCAGTGAGTTACGTCCCGTCAAACATGCTTTCGATGCAGG
AATAAAAGCGCAGCAAGGTATTGATTGGTAA

Upstream 100 bases:

>100_bases
TATTTGATGGGCGATGACAGCCGTAGAAAAACGGGGATCAGCTTCGATGCACAGCCCGGCCGTAAACCTGGTCCAGCTGA
ATAAAAGGAACGTAATCATT

Downstream 100 bases:

>100_bases
TATTTTATAAGCGTTAAAAATAATATTGCCGCAGTCCAAAAAACTGCGGCAATAAGCATTATTCACGTCGCTATTGATGT
CTAATGACAGACGCGGTTAA

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MSEDRHQQRQQRLKEKVDSRIAAAQEVRGILIVFTGNGKGKTTAAFGTVTRAVGHGLKAGVIQFIKGEWPNGEKNLLQQH
GVEFQVMATGFTWNTQDRETDTVACLGVWQHALRMLADPTLDLVVLDELTYMIAYDYLPLDEVINALNQRPAHQTVIITG
RGCHRDLLEMADTVSELRPVKHAFDAGIKAQQGIDW

Sequences:

>Translated_196_residues
MSEDRHQQRQQRLKEKVDSRIAAAQEVRGILIVFTGNGKGKTTAAFGTVTRAVGHGLKAGVIQFIKGEWPNGEKNLLQQH
GVEFQVMATGFTWNTQDRETDTVACLGVWQHALRMLADPTLDLVVLDELTYMIAYDYLPLDEVINALNQRPAHQTVIITG
RGCHRDLLEMADTVSELRPVKHAFDAGIKAQQGIDW
>Mature_195_residues
SEDRHQQRQQRLKEKVDSRIAAAQEVRGILIVFTGNGKGKTTAAFGTVTRAVGHGLKAGVIQFIKGEWPNGEKNLLQQHG
VEFQVMATGFTWNTQDRETDTVACLGVWQHALRMLADPTLDLVVLDELTYMIAYDYLPLDEVINALNQRPAHQTVIITGR
GCHRDLLEMADTVSELRPVKHAFDAGIKAQQGIDW

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=196, Percent_Identity=79.0816326530612, Blast_Score=338, Evalue=2e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 21889; Mature: 21758

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEDRHQQRQQRLKEKVDSRIAAAQEVRGILIVFTGNGKGKTTAAFGTVTRAVGHGLKAG
CCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHH
VIQFIKGEWPNGEKNLLQQHGVEFQVMATGFTWNTQDRETDTVACLGVWQHALRMLADPT
HHHHHHCCCCCCHHHHHHHCCCEEEEEEECEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
LDLVVLDELTYMIAYDYLPLDEVINALNQRPAHQTVIITGRGCHRDLLEMADTVSELRPV
CHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
KHAFDAGIKAQQGIDW
HHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SEDRHQQRQQRLKEKVDSRIAAAQEVRGILIVFTGNGKGKTTAAFGTVTRAVGHGLKAG
CCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHH
VIQFIKGEWPNGEKNLLQQHGVEFQVMATGFTWNTQDRETDTVACLGVWQHALRMLADPT
HHHHHHCCCCCCHHHHHHHCCCEEEEEEECEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
LDLVVLDELTYMIAYDYLPLDEVINALNQRPAHQTVIITGRGCHRDLLEMADTVSELRPV
CHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
KHAFDAGIKAQQGIDW
HHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]