Click here to switch to the map view.

The map label for this gene is modF [H]

Identifier: 153947841

GI number: 153947841

Start: 3221251

End: 3222741

Strand: Direct

Name: modF [H]

Synonym: YpsIP31758_2853

Alternate gene names: 153947841

Gene position: 3221251-3222741 (Clockwise)

Preceding gene: 153948149

Following gene: 153947206

Centisome position: 68.2

GC content: 51.84

Gene sequence:

>1491_bases
ATGTCTGAGTTGCAAATATCGCAAGGTTGTTTTCGCCTGAGTGACACACAGACACTCATCTTGCCAGCACTACATATCCA
GGCGGGTGACTGTTGGGCATTTGTCGGGGCCAATGGCAGTGGTAAATCTGCGTTAGCCAAGGCCCTGTCTGGAGAGCTTA
CCCTGCTGGAGGGCAGCCGCCAAAGCCACTTCCGCCATGCCGTGCGTTTATCATTCGAACAACTACAGCAACTGCTCAAT
GAAGAGTGGCAACGTAATAACACCGACCTGCTCAGTGCTGATGAAGATGACACTGGCCGTACTACCGCCGAAATTATTCA
GGAAGCGGCCCGTGACCCGCAGCGCTGTCAACAACTGGCAGCGCTATTTGGTATCAGCCACTTGCTTTCTCGCCGCTTCA
AATACCTTTCTACGGGGGAAACCCGTAAAACATTGCTGTGTCAGGCGCTGATGCCGCAACCGGACCTGCTGATTCTGGAT
GAGCCCTTTGATGGCCTGGATGTCGCGGCTCGGGCGCAGTTAGCCGAGATGCTATCCACACTTTCGGCCCAAGGCGTCAC
CCTGGTATTGGTCCTCAACCGCTTTGATGATATCCCTGATTTTGTGCAGTACGTTGGCGTATTGGCTGATTGCCACCTGA
CCCACATGGGGCCGCGCCAGCAAATTCTGTCGGAAGCGTTAATTGCCCAATTGGCACACAGTGAAAATCTGGATGGGCTG
TCACTGCCGGAAACGGAGGATCCACAGCACCACCTACGAATACCGAAAAATGAACCCTTGATCATACTGAATGACGGGGT
GGTGGAGTACAACGACCGCCCTATCCTGCATAACCTGAGCTGGCAAGTGAACCCCGGTGAACACTGGCAGATTATCGGCC
AGAATGGTGCAGGGAAATCCACCTTACTCAGCCTGATAACTGGCGACCATCCCCAAGGATACAGTAATGATTTAACGCTG
TTTGGCCGCCGCCGTGGCAGTGGTGAAACCATCTGGGACATCAAACGCCATATTGGTTATGTCAGCGGCAGCCTCCATCT
GGACTACCGGGTTAGCACCCGTGTACGTACCGTGATTTTATCCGGTTTTTTCGATTCGATTGGTCTTTACCAAGCAGCCT
CTGATCGTCAACAACAATTAGCAGATCAATGGCTGTCTTTACTGGGGTTTTCCACCTCCGTCGCCAACCAACCTTTCCAC
AGCTTATCTTGGGGGCAACAGCGTCTGGTCTTGATCGCCCGAGCATTGGTTAAGCACCCAGCGCTCCTGATCCTGGATGA
ACCCTTACAAGGGCTGGATCCGCTTAACCGTTTGTTAGTGCGCCGTTTTATTGATGTGATGATCGGTGAAGGAGAAACCC
AATTATTGTTCGTTTCTCACCATGCCGAGGATGCACCCCAGTGTATTACGCACCGCTTAACCTTTGTGCCATTTGGCGAT
ATTTATCACTATCAACAAGAAAAATTACCAAGCCAACCACAGGTAAAATAA

Upstream 100 bases:

>100_bases
CCTAGTAATCACTGTTAGACCATACATTTGTTCGTTGACATTTTTCGTCTTTCGGCTTATCCCTAACATCTTTACTACGT
TGTAAAATATGGGAAATATG

Downstream 100 bases:

>100_bases
GCATTTTTCACAGTTTTACTGAGCGTCACCCAATGCAACCCCCACTGACCCGACCTTTACTCTGGTGCCAGCATGTTATT
ATTCTTACCACCAGCCACTT

Product: molybdenum transport ATP-binding protein ModF

Products: ADP; phosphate; molybdate

Alternate protein names: Photorepair protein PhrA [H]

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MSELQISQGCFRLSDTQTLILPALHIQAGDCWAFVGANGSGKSALAKALSGELTLLEGSRQSHFRHAVRLSFEQLQQLLN
EEWQRNNTDLLSADEDDTGRTTAEIIQEAARDPQRCQQLAALFGISHLLSRRFKYLSTGETRKTLLCQALMPQPDLLILD
EPFDGLDVAARAQLAEMLSTLSAQGVTLVLVLNRFDDIPDFVQYVGVLADCHLTHMGPRQQILSEALIAQLAHSENLDGL
SLPETEDPQHHLRIPKNEPLIILNDGVVEYNDRPILHNLSWQVNPGEHWQIIGQNGAGKSTLLSLITGDHPQGYSNDLTL
FGRRRGSGETIWDIKRHIGYVSGSLHLDYRVSTRVRTVILSGFFDSIGLYQAASDRQQQLADQWLSLLGFSTSVANQPFH
SLSWGQQRLVLIARALVKHPALLILDEPLQGLDPLNRLLVRRFIDVMIGEGETQLLFVSHHAEDAPQCITHRLTFVPFGD
IYHYQQEKLPSQPQVK

Sequences:

>Translated_496_residues
MSELQISQGCFRLSDTQTLILPALHIQAGDCWAFVGANGSGKSALAKALSGELTLLEGSRQSHFRHAVRLSFEQLQQLLN
EEWQRNNTDLLSADEDDTGRTTAEIIQEAARDPQRCQQLAALFGISHLLSRRFKYLSTGETRKTLLCQALMPQPDLLILD
EPFDGLDVAARAQLAEMLSTLSAQGVTLVLVLNRFDDIPDFVQYVGVLADCHLTHMGPRQQILSEALIAQLAHSENLDGL
SLPETEDPQHHLRIPKNEPLIILNDGVVEYNDRPILHNLSWQVNPGEHWQIIGQNGAGKSTLLSLITGDHPQGYSNDLTL
FGRRRGSGETIWDIKRHIGYVSGSLHLDYRVSTRVRTVILSGFFDSIGLYQAASDRQQQLADQWLSLLGFSTSVANQPFH
SLSWGQQRLVLIARALVKHPALLILDEPLQGLDPLNRLLVRRFIDVMIGEGETQLLFVSHHAEDAPQCITHRLTFVPFGD
IYHYQQEKLPSQPQVK
>Mature_495_residues
SELQISQGCFRLSDTQTLILPALHIQAGDCWAFVGANGSGKSALAKALSGELTLLEGSRQSHFRHAVRLSFEQLQQLLNE
EWQRNNTDLLSADEDDTGRTTAEIIQEAARDPQRCQQLAALFGISHLLSRRFKYLSTGETRKTLLCQALMPQPDLLILDE
PFDGLDVAARAQLAEMLSTLSAQGVTLVLVLNRFDDIPDFVQYVGVLADCHLTHMGPRQQILSEALIAQLAHSENLDGLS
LPETEDPQHHLRIPKNEPLIILNDGVVEYNDRPILHNLSWQVNPGEHWQIIGQNGAGKSTLLSLITGDHPQGYSNDLTLF
GRRRGSGETIWDIKRHIGYVSGSLHLDYRVSTRVRTVILSGFFDSIGLYQAASDRQQQLADQWLSLLGFSTSVANQPFHS
LSWGQQRLVLIARALVKHPALLILDEPLQGLDPLNRLLVRRFIDVMIGEGETQLLFVSHHAEDAPQCITHRLTFVPFGDI
YHYQQEKLPSQPQVK

Specific function: Involved in the transport of molybdenum into the cell. Involved in photorepair. Could act on UV-induced DNA damage other than pyrimidine dimers [H]

COG id: COG1119

COG function: function code P; ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Escherichia coli, GI1786975, Length=489, Percent_Identity=74.2331288343558, Blast_Score=759, Evalue=0.0,
Organism=Escherichia coli, GI48995001, Length=462, Percent_Identity=24.4588744588745, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1788506, Length=481, Percent_Identity=24.3243243243243, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787041, Length=522, Percent_Identity=22.6053639846743, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI48994943, Length=467, Percent_Identity=23.7687366167024, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790190, Length=464, Percent_Identity=25.2155172413793, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789991, Length=461, Percent_Identity=23.8611713665944, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1790544, Length=227, Percent_Identity=30.3964757709251, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787792, Length=472, Percent_Identity=23.3050847457627, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787029, Length=208, Percent_Identity=30.2884615384615, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790525, Length=471, Percent_Identity=21.656050955414, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789593, Length=185, Percent_Identity=28.6486486486486, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788225, Length=248, Percent_Identity=26.6129032258064, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081782, Length=286, Percent_Identity=23.4265734265734, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788472, Length=508, Percent_Identity=22.0472440944882, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789864, Length=216, Percent_Identity=26.8518518518519, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786319, Length=237, Percent_Identity=26.1603375527426, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1786563, Length=200, Percent_Identity=30, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787758, Length=208, Percent_Identity=28.3653846153846, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1788450, Length=177, Percent_Identity=28.8135593220339, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786803, Length=260, Percent_Identity=24.2307692307692, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI1790162, Length=232, Percent_Identity=23.7068965517241, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=206, Percent_Identity=30.5825242718447, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI115533608, Length=217, Percent_Identity=28.110599078341, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320266, Length=389, Percent_Identity=29.0488431876607, Blast_Score=151, Evalue=2e-37,
Organism=Drosophila melanogaster, GI221512771, Length=215, Percent_Identity=26.046511627907, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24650853, Length=223, Percent_Identity=30.4932735426009, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24650855, Length=223, Percent_Identity=30.4932735426009, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI281362751, Length=204, Percent_Identity=30.8823529411765, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574744, Length=226, Percent_Identity=26.1061946902655, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24643674, Length=229, Percent_Identity=25.3275109170306, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI85725262, Length=209, Percent_Identity=30.622009569378, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: 3.6.3.29

Molecular weight: Translated: 55445; Mature: 55314

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELQISQGCFRLSDTQTLILPALHIQAGDCWAFVGANGSGKSALAKALSGELTLLEGSR
CCCCCCCCCCEEECCCCEEEEEEEEEECCCEEEEEECCCCCHHHHHHHHCCCEEEEECCH
QSHFRHAVRLSFEQLQQLLNEEWQRNNTDLLSADEDDTGRTTAEIIQEAARDPQRCQQLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHCCCHHHHHHHH
ALFGISHLLSRRFKYLSTGETRKTLLCQALMPQPDLLILDEPFDGLDVAARAQLAEMLST
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
LSAQGVTLVLVLNRFDDIPDFVQYVGVLADCHLTHMGPRQQILSEALIAQLAHSENLDGL
HCCCCEEEEEEEHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
SLPETEDPQHHLRIPKNEPLIILNDGVVEYNDRPILHNLSWQVNPGEHWQIIGQNGAGKS
CCCCCCCCHHHEECCCCCCEEEEECCEEEECCCCEEECCCEEECCCCCEEEEECCCCCHH
TLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDIKRHIGYVSGSLHLDYRVSTRVRTVIL
HHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCEECCEEEEEEEEHHHHHHHHH
SGFFDSIGLYQAASDRQQQLADQWLSLLGFSTSVANQPFHSLSWGQQRLVLIARALVKHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHCCCHHHHHHHHHHHHHCC
ALLILDEPLQGLDPLNRLLVRRFIDVMIGEGETQLLFVSHHAEDAPQCITHRLTFVPFGD
EEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHEEEEECHH
IYHYQQEKLPSQPQVK
HHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SELQISQGCFRLSDTQTLILPALHIQAGDCWAFVGANGSGKSALAKALSGELTLLEGSR
CCCCCCCCCEEECCCCEEEEEEEEEECCCEEEEEECCCCCHHHHHHHHCCCEEEEECCH
QSHFRHAVRLSFEQLQQLLNEEWQRNNTDLLSADEDDTGRTTAEIIQEAARDPQRCQQLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHCCCHHHHHHHH
ALFGISHLLSRRFKYLSTGETRKTLLCQALMPQPDLLILDEPFDGLDVAARAQLAEMLST
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
LSAQGVTLVLVLNRFDDIPDFVQYVGVLADCHLTHMGPRQQILSEALIAQLAHSENLDGL
HCCCCEEEEEEEHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
SLPETEDPQHHLRIPKNEPLIILNDGVVEYNDRPILHNLSWQVNPGEHWQIIGQNGAGKS
CCCCCCCCHHHEECCCCCCEEEEECCEEEECCCCEEECCCEEECCCCCEEEEECCCCCHH
TLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDIKRHIGYVSGSLHLDYRVSTRVRTVIL
HHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCEECCEEEEEEEEHHHHHHHHH
SGFFDSIGLYQAASDRQQQLADQWLSLLGFSTSVANQPFHSLSWGQQRLVLIARALVKHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHCCCHHHHHHHHHHHHHCC
ALLILDEPLQGLDPLNRLLVRRFIDVMIGEGETQLLFVSHHAEDAPQCITHRLTFVPFGD
EEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHEEEEECHH
IYHYQQEKLPSQPQVK
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; molybdate

Specific reaction: ATP + H2O + molybdate(out) = ADP + phosphate + molybdate(in)

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8564363; 8550508; 8905232; 9278503; 8310005 [H]