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The map label for this gene is livM [H]

Identifier: 153952098

GI number: 153952098

Start: 696155

End: 697207

Strand: Direct

Name: livM [H]

Synonym: JJD26997_0772

Alternate gene names: 153952098

Gene position: 696155-697207 (Clockwise)

Preceding gene: 153951345

Following gene: 153951149

Centisome position: 37.73

GC content: 32.29

Gene sequence:

>1053_bases
ATGATGGTTAAAATTAAGGTTTCACATTTAATCTTTTTGATTGCTTCAATTATTTTTATTTTCATTTCTCCTTATATTTT
TGGGGACTATGGATTAAACATTGTTAATCAAATTGCTATTTTTATTATTTTGGCTGTGAGTTACAACCTTATTAATGGTG
TAACTGGACAATTTTCACTAGAACCTAATGGATTTGTTGCAATTGGAGCTTATGCGGCTACTTTAGTTCTTTTAAGTGCT
GATGCAAAAAATGATCAGTTTTTTTTAGATGGTCCTAGTTCTTTTATTTTAGCCATCCATTCAAATTCTTTTATTCTAGC
TTTAATTGTAGCTGGAATTTGCTCATCTTTGCTTGCCCTGATTTTAGCTTTTGCTGTATTTCGCGTAAGAGGGGATTATT
TAGCTATTGTAACTTTAGGCTTTGGAATAATTATTAAAATAGCTGCTATTAATTTTCCTTCTATTACTAATGGCTCAAGA
GGGCTGGTAGATATTCCGCAATTTTCCACGATCTATTGGACGGGTGGTATTGCTATTGTAGCGGTTATTTTAATTTTGAA
TATAGTTTATTCTAAATATGGTCGTGCAATGAAGGCTATAAGAGATGATGAAGATGCTGCAAGCGCTATGGGGATAAATA
CTTTTTGGATAAAAACTTTAGCTTTTAGCACTTCAGCATTTTTAGAAGGTGTAGGTGGCGGACTTTTAGCTTGTCTGTTG
ACTACCGTATCTCCAACTCAATTTGATTTTTTACTTACTTTTCAGCTTTTGATTATTATTGTTTTGGGTGGACTTGGTTC
TACTACAGGTGCTATTATAGGTGCGATATTGGTTATTGGTGGAAGTGAGTGGCTTAGATTTTTAGATGAATTAAATATAA
AAATAGATTCTTTAAATCTTGATATCCAATCAACACCAGGGTTTAGAATGGTTGTTTTTTCTATTGTTCTGATTTTAGTA
ATGCTTTTTGCAAGAAAAGGTATAATGGGTTATGATGAGTTGAGCGATGTGATTAGAGGGATTAAAAAGCGTTTTAAAAG
GAGTGAAAAATGA

Upstream 100 bases:

>100_bases
CAGGCTTTAAAGATGCATTTGCTTTTATTTTTTTGGTGTTTATATTGTTATTTAGGCCTACAGGAATTTTAGGTATAAAT
TTTGAAAAGAGTAGGTTTTG

Downstream 100 bases:

>100_bases
TTTTGGAATTAAAACAAATTTCAAAAAGTTTTGGTAGTGTTAAGGCTATTAATGAAACTTCTTTTAAAATCAATGAGGGT
GAAATTTTTGCTTTAATTGG

Product: high affinity branched-chain amino acid ABC transporter, permease protein

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MMVKIKVSHLIFLIASIIFIFISPYIFGDYGLNIVNQIAIFIILAVSYNLINGVTGQFSLEPNGFVAIGAYAATLVLLSA
DAKNDQFFLDGPSSFILAIHSNSFILALIVAGICSSLLALILAFAVFRVRGDYLAIVTLGFGIIIKIAAINFPSITNGSR
GLVDIPQFSTIYWTGGIAIVAVILILNIVYSKYGRAMKAIRDDEDAASAMGINTFWIKTLAFSTSAFLEGVGGGLLACLL
TTVSPTQFDFLLTFQLLIIIVLGGLGSTTGAIIGAILVIGGSEWLRFLDELNIKIDSLNLDIQSTPGFRMVVFSIVLILV
MLFARKGIMGYDELSDVIRGIKKRFKRSEK

Sequences:

>Translated_350_residues
MMVKIKVSHLIFLIASIIFIFISPYIFGDYGLNIVNQIAIFIILAVSYNLINGVTGQFSLEPNGFVAIGAYAATLVLLSA
DAKNDQFFLDGPSSFILAIHSNSFILALIVAGICSSLLALILAFAVFRVRGDYLAIVTLGFGIIIKIAAINFPSITNGSR
GLVDIPQFSTIYWTGGIAIVAVILILNIVYSKYGRAMKAIRDDEDAASAMGINTFWIKTLAFSTSAFLEGVGGGLLACLL
TTVSPTQFDFLLTFQLLIIIVLGGLGSTTGAIIGAILVIGGSEWLRFLDELNIKIDSLNLDIQSTPGFRMVVFSIVLILV
MLFARKGIMGYDELSDVIRGIKKRFKRSEK
>Mature_350_residues
MMVKIKVSHLIFLIASIIFIFISPYIFGDYGLNIVNQIAIFIILAVSYNLINGVTGQFSLEPNGFVAIGAYAATLVLLSA
DAKNDQFFLDGPSSFILAIHSNSFILALIVAGICSSLLALILAFAVFRVRGDYLAIVTLGFGIIIKIAAINFPSITNGSR
GLVDIPQFSTIYWTGGIAIVAVILILNIVYSKYGRAMKAIRDDEDAASAMGINTFWIKTLAFSTSAFLEGVGGGLLACLL
TTVSPTQFDFLLTFQLLIIIVLGGLGSTTGAIIGAILVIGGSEWLRFLDELNIKIDSLNLDIQSTPGFRMVVFSIVLILV
MLFARKGIMGYDELSDVIRGIKKRFKRSEK

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=304, Percent_Identity=30.9210526315789, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851
- InterPro:   IPR021807 [H]

Pfam domain/function: PF02653 BPD_transp_2; PF11862 DUF3382 [H]

EC number: NA

Molecular weight: Translated: 37847; Mature: 37847

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVKIKVSHLIFLIASIIFIFISPYIFGDYGLNIVNQIAIFIILAVSYNLINGVTGQFSL
CEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
EPNGFVAIGAYAATLVLLSADAKNDQFFLDGPSSFILAIHSNSFILALIVAGICSSLLAL
CCCCEEEEHHHHHHHHHEECCCCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHH
ILAFAVFRVRGDYLAIVTLGFGIIIKIAAINFPSITNGSRGLVDIPQFSTIYWTGGIAIV
HHHHHHHHHCCCEEEEHHHHHHHHHHHHEECCCCCCCCCCCCEECCCCCEEEEECHHHHH
AVILILNIVYSKYGRAMKAIRDDEDAASAMGINTFWIKTLAFSTSAFLEGVGGGLLACLL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHH
TTVSPTQFDFLLTFQLLIIIVLGGLGSTTGAIIGAILVIGGSEWLRFLDELNIKIDSLNL
HHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEEEE
DIQSTPGFRMVVFSIVLILVMLFARKGIMGYDELSDVIRGIKKRFKRSEK
EEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMVKIKVSHLIFLIASIIFIFISPYIFGDYGLNIVNQIAIFIILAVSYNLINGVTGQFSL
CEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
EPNGFVAIGAYAATLVLLSADAKNDQFFLDGPSSFILAIHSNSFILALIVAGICSSLLAL
CCCCEEEEHHHHHHHHHEECCCCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHH
ILAFAVFRVRGDYLAIVTLGFGIIIKIAAINFPSITNGSRGLVDIPQFSTIYWTGGIAIV
HHHHHHHHHCCCEEEEHHHHHHHHHHHHEECCCCCCCCCCCCEECCCCCEEEEECHHHHH
AVILILNIVYSKYGRAMKAIRDDEDAASAMGINTFWIKTLAFSTSAFLEGVGGGLLACLL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHH
TTVSPTQFDFLLTFQLLIIIVLGGLGSTTGAIIGAILVIGGSEWLRFLDELNIKIDSLNL
HHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEEEE
DIQSTPGFRMVVFSIVLILVMLFARKGIMGYDELSDVIRGIKKRFKRSEK
EEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043 [H]