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The map label for this gene is livH [H]

Identifier: 153951345

GI number: 153951345

Start: 695259

End: 696155

Strand: Direct

Name: livH [H]

Synonym: JJD26997_0771

Alternate gene names: 153951345

Gene position: 695259-696155 (Clockwise)

Preceding gene: 153951623

Following gene: 153952098

Centisome position: 37.68

GC content: 34.34

Gene sequence:

>897_bases
ATGGATTCTACTTTATTTTTACAACAACTTGTTAATGGACTTAGTTTGGGCAGTATGTATGCCCTTATTGCTGTTGGCTA
TACGATGGTTTATGGCGTGTTAAGACTTATTAATTTTGCTCACGGCGATATTATGATGGTTGGTGCTTATGCAGCTCTTT
TTTGCATGACTAATCTAAATGTTCCTTTTCTAGGAGCTTTGTCTTTGGCGATGATTTTTGCTGCCTGTGTTGGAATAGCT
ACAGATAGAATCGCTTATAAACCTTTAAGACAGACTCCTAGAATTTCATTGTTAATTACGGCAATTGGTATTAGTTTTTT
CTTGCAAAATCTTTTTAATATGCTTTTTACTTCAACACCTAGAACTTTTGCACCGCCAAGTTATTTTGAGGAAAGTGTTA
ATTTTGGTGGAGTGATAACAACTTATGGTTCTTTAATGGTTCCTGCTCTTACATTTGTTATTTTAATAACAGTGTTATGG
ATTTTGTATAAAAGCAAATATGGTATAGCTATTCGTGCTTTGGCATTTGATATACAAACAGTAAATTTAATGGGTATAGA
TGCAAATCGTATGATTGCTGTAGTTTTTGCCCTAGGTTCAGCTTTGGCAGCAGTTGGGGGTGTTTTTTGGGCTGCAAATT
ATTACTCTGTTGAACCTACTATGGGAACTTTAATAGGTTTGAAAGCTTTTGCTGCTGCAGTTTTAGGAGGTATAGGTTCT
GTAGTAGGTGCAGTTTTGGGTGGACTTATTATAGGATTTACTGAAGTTGTTGTTGTGGCTTTTTTTCCAGATTTATCAGG
CTTTAAAGATGCATTTGCTTTTATTTTTTTGGTGTTTATATTGTTATTTAGGCCTACAGGAATTTTAGGTATAAATTTTG
AAAAGAGTAGGTTTTGA

Upstream 100 bases:

>100_bases
ACAGGAAATGCAACTCGTTCTGTAGTGGTTAAAGAAATTAAAAATCAAAAGCAAAATTATAAAGATATTATCAATCCTTA
AAGGAAAAAATAGAAAGATT

Downstream 100 bases:

>100_bases
TGATGGTTAAAATTAAGGTTTCACATTTAATCTTTTTGATTGCTTCAATTATTTTTATTTTCATTTCTCCTTATATTTTT
GGGGACTATGGATTAAACAT

Product: high affinity branched-chain amino acid ABC transporter, permease protein

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MDSTLFLQQLVNGLSLGSMYALIAVGYTMVYGVLRLINFAHGDIMMVGAYAALFCMTNLNVPFLGALSLAMIFAACVGIA
TDRIAYKPLRQTPRISLLITAIGISFFLQNLFNMLFTSTPRTFAPPSYFEESVNFGGVITTYGSLMVPALTFVILITVLW
ILYKSKYGIAIRALAFDIQTVNLMGIDANRMIAVVFALGSALAAVGGVFWAANYYSVEPTMGTLIGLKAFAAAVLGGIGS
VVGAVLGGLIIGFTEVVVVAFFPDLSGFKDAFAFIFLVFILLFRPTGILGINFEKSRF

Sequences:

>Translated_298_residues
MDSTLFLQQLVNGLSLGSMYALIAVGYTMVYGVLRLINFAHGDIMMVGAYAALFCMTNLNVPFLGALSLAMIFAACVGIA
TDRIAYKPLRQTPRISLLITAIGISFFLQNLFNMLFTSTPRTFAPPSYFEESVNFGGVITTYGSLMVPALTFVILITVLW
ILYKSKYGIAIRALAFDIQTVNLMGIDANRMIAVVFALGSALAAVGGVFWAANYYSVEPTMGTLIGLKAFAAAVLGGIGS
VVGAVLGGLIIGFTEVVVVAFFPDLSGFKDAFAFIFLVFILLFRPTGILGINFEKSRF
>Mature_298_residues
MDSTLFLQQLVNGLSLGSMYALIAVGYTMVYGVLRLINFAHGDIMMVGAYAALFCMTNLNVPFLGALSLAMIFAACVGIA
TDRIAYKPLRQTPRISLLITAIGISFFLQNLFNMLFTSTPRTFAPPSYFEESVNFGGVITTYGSLMVPALTFVILITVLW
ILYKSKYGIAIRALAFDIQTVNLMGIDANRMIAVVFALGSALAAVGGVFWAANYYSVEPTMGTLIGLKAFAAAVLGGIGS
VVGAVLGGLIIGFTEVVVVAFFPDLSGFKDAFAFIFLVFILLFRPTGILGINFEKSRF

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=299, Percent_Identity=41.4715719063545, Blast_Score=193, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 32034; Mature: 32034

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTLFLQQLVNGLSLGSMYALIAVGYTMVYGVLRLINFAHGDIMMVGAYAALFCMTNLN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
VPFLGALSLAMIFAACVGIATDRIAYKPLRQTPRISLLITAIGISFFLQNLFNMLFTSTP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
RTFAPPSYFEESVNFGGVITTYGSLMVPALTFVILITVLWILYKSKYGIAIRALAFDIQT
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHEEHEE
VNLMGIDANRMIAVVFALGSALAAVGGVFWAANYYSVEPTMGTLIGLKAFAAAVLGGIGS
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHH
VVGAVLGGLIIGFTEVVVVAFFPDLSGFKDAFAFIFLVFILLFRPTGILGINFEKSRF
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCHHCCC
>Mature Secondary Structure
MDSTLFLQQLVNGLSLGSMYALIAVGYTMVYGVLRLINFAHGDIMMVGAYAALFCMTNLN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
VPFLGALSLAMIFAACVGIATDRIAYKPLRQTPRISLLITAIGISFFLQNLFNMLFTSTP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
RTFAPPSYFEESVNFGGVITTYGSLMVPALTFVILITVLWILYKSKYGIAIRALAFDIQT
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHEEHEE
VNLMGIDANRMIAVVFALGSALAAVGGVFWAANYYSVEPTMGTLIGLKAFAAAVLGGIGS
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHH
VVGAVLGGLIIGFTEVVVVAFFPDLSGFKDAFAFIFLVFILLFRPTGILGINFEKSRF
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043; 2509433 [H]