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The map label for this gene is hup

Identifier: 153951444

GI number: 153951444

Start: 800794

End: 801090

Strand: Direct

Name: hup

Synonym: JJD26997_0901

Alternate gene names: 153951444

Gene position: 800794-801090 (Clockwise)

Preceding gene: 153952319

Following gene: 153952497

Centisome position: 43.4

GC content: 35.69

Gene sequence:

>297_bases
ATGACTAAAGCAGATTTCATTTCATTAGTTGCTCAAACAGCTGGGCTAACAAAAAAAGACGCTACCACTGCTACTGATGC
AGTTATTTCTACTATTACTGATGTTTTAGCTAAAGGTGATAGCATCAGTTTTATTGGTTTTGGTACTTTTTCAACTCAAG
AAAGAGCTGCTAGAGAAGCTAGAGTACCAAGCACAGGAAAAACAATCAAAGTTCCTGCTACAAGAGTTGCAAAATTTAAG
GTAGGTAAAAACCTTAAAGAAGCTGTTGCAAAAGCAAGCGGCAAAAAGAAAAAATAA

Upstream 100 bases:

>100_bases
AAAGTTTTTTGAAAAAAACTTAAAAAAAGCTGTTTTTTACTTGATATTGTTTTTTAAATATGCTAAAATTAGGCGTTTCA
ATTAAAACAAAGGAGCTTTT

Downstream 100 bases:

>100_bases
AACTTCGGCTAGATAAATTCTAGCCTTCTTTCTTAATTAATTCAGATATTTTGTATCTTTTATTTACTTTATTTTTTTAA
ACTTTTATAGAACTATCATT

Product: DNA-binding protein HU

Products: NA

Alternate protein names: HCj

Number of amino acids: Translated: 98; Mature: 97

Protein sequence:

>98_residues
MTKADFISLVAQTAGLTKKDATTATDAVISTITDVLAKGDSISFIGFGTFSTQERAAREARVPSTGKTIKVPATRVAKFK
VGKNLKEAVAKASGKKKK

Sequences:

>Translated_98_residues
MTKADFISLVAQTAGLTKKDATTATDAVISTITDVLAKGDSISFIGFGTFSTQERAAREARVPSTGKTIKVPATRVAKFK
VGKNLKEAVAKASGKKKK
>Mature_97_residues
TKADFISLVAQTAGLTKKDATTATDAVISTITDVLAKGDSISFIGFGTFSTQERAAREARVPSTGKTIKVPATRVAKFKV
GKNLKEAVAKASGKKKK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family

Homologues:

Organism=Escherichia coli, GI1786644, Length=89, Percent_Identity=44.9438202247191, Blast_Score=82, Evalue=5e-18,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=42.6966292134831, Blast_Score=77, Evalue=3e-16,
Organism=Escherichia coli, GI1788005, Length=95, Percent_Identity=33.6842105263158, Blast_Score=64, Evalue=3e-12,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): DBH_CAMJE (Q46121)

Other databases:

- EMBL:   L25627
- EMBL:   AY751940
- EMBL:   AY751941
- EMBL:   AY751943
- EMBL:   AY751945
- EMBL:   AY751946
- EMBL:   AY751954
- EMBL:   AY751955
- EMBL:   AY751959
- EMBL:   AY751960
- EMBL:   AY751980
- EMBL:   AY751982
- EMBL:   AY751983
- EMBL:   AY751984
- EMBL:   AY751992
- EMBL:   AY751994
- EMBL:   AY751995
- EMBL:   AY751996
- EMBL:   AY751997
- EMBL:   AY751998
- EMBL:   AY751999
- EMBL:   AY752000
- EMBL:   AY752001
- EMBL:   AY752002
- EMBL:   AY752003
- EMBL:   AY752004
- EMBL:   AY752005
- EMBL:   AY752017
- EMBL:   AL111168
- PIR:   I40616
- RefSeq:   YP_002344311.1
- ProteinModelPortal:   Q46121
- SMR:   Q46121
- IntAct:   Q46121
- MINT:   MINT-6484961
- GeneID:   905212
- GenomeReviews:   AL111168_GR
- KEGG:   cje:Cj0913c
- HOGENOM:   HBG705085
- OMA:   NESKTHF
- ProtClustDB:   CLSK878989
- BioCyc:   CJEJ192222:CJ0913C-MONOMER
- InterPro:   IPR000119
- InterPro:   IPR010992
- Gene3D:   G3DSA:4.10.520.10
- PRINTS:   PR01727
- SMART:   SM00411

Pfam domain/function: PF00216 Bac_DNA_binding; SSF47729 IHF_like_DNA_bnd

EC number: NA

Molecular weight: Translated: 10274; Mature: 10143

Theoretical pI: Translated: 11.08; Mature: 11.08

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKADFISLVAQTAGLTKKDATTATDAVISTITDVLAKGDSISFIGFGTFSTQERAAREA
CCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHC
RVPSTGKTIKVPATRVAKFKVGKNLKEAVAKASGKKKK
CCCCCCCEEECCHHHHHHHHHCCCHHHHHHHHCCCCCC
>Mature Secondary Structure 
TKADFISLVAQTAGLTKKDATTATDAVISTITDVLAKGDSISFIGFGTFSTQERAAREA
CHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHC
RVPSTGKTIKVPATRVAKFKVGKNLKEAVAKASGKKKK
CCCCCCCEEECCHHHHHHHHHCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8063109; 10688204