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The map label for this gene is thiJ [H]

Identifier: 153951347

GI number: 153951347

Start: 809984

End: 810553

Strand: Direct

Name: thiJ [H]

Synonym: JJD26997_0914

Alternate gene names: 153951347

Gene position: 809984-810553 (Clockwise)

Preceding gene: 153951511

Following gene: 153952279

Centisome position: 43.9

GC content: 32.81

Gene sequence:

>570_bases
ATGAGTAAAAAAGTATTAATTCCATTAGCTCAAGGTTTTGAAGAAGCTGAGTTTATAGGAATTGTGGATGTTTTAAAACG
AGCAAGAGAATTAAATCCAGATTTGGAAGTTATTATAGCTTCGTTAAATAGTGAGTTATTAGTAAAGGGTGCTAATGGCA
TTAGTATAAAAGCAGATTGTTCTATAGAGAGTGTTGATATAGAAAATCTAGATGCCATTGCTTTAGCGGGTGGTTTTGAA
GGTATGATGAATCTTAAGAATTCAAATGTTATTTTAAATATCATCAAACAACTTCATAGTAAAAATAAAATTGTTGCTGC
AATCTGTGCTTCTCCTATAGTCCTAAATGAAGCAGGTGTTTTAGAGGGCGAGTTTGCTTGCTATCCTAGTTGTGAAGTTG
GACTTAATGGAAATCGTGTTAACAAGGCTGTAGTTGTAAATAAAAATGTTATAACTTCAGCAGGTCCAGCTACGGCAATT
CTTTTTGGTTTAGAACTAGCTAAAAAGTTATGCGGTGATGAAATTTATCAAAAATTATACGAGGGAATGTTGCTACCTTT
GACAAAATAG

Upstream 100 bases:

>100_bases
TTTTTAATGATTGTTTTGGTTATAGGTTTTAATCGTCAAATGATGCAAAAAAACAAAGAAAGAGAAGAAAGATTTAAAAA
ATATAAAAAAGGAGAACAAA

Downstream 100 bases:

>100_bases
TTCAAATGGTAGTTTTTCTACCATTTGAACTAAAATAAAGCTTGAGGATTTTCTTTTTTTATTTTTTCCTTAGGCAGTTC
AAAACCTCCAAGCATATGAA

Product: 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MSKKVLIPLAQGFEEAEFIGIVDVLKRARELNPDLEVIIASLNSELLVKGANGISIKADCSIESVDIENLDAIALAGGFE
GMMNLKNSNVILNIIKQLHSKNKIVAAICASPIVLNEAGVLEGEFACYPSCEVGLNGNRVNKAVVVNKNVITSAGPATAI
LFGLELAKKLCGDEIYQKLYEGMLLPLTK

Sequences:

>Translated_189_residues
MSKKVLIPLAQGFEEAEFIGIVDVLKRARELNPDLEVIIASLNSELLVKGANGISIKADCSIESVDIENLDAIALAGGFE
GMMNLKNSNVILNIIKQLHSKNKIVAAICASPIVLNEAGVLEGEFACYPSCEVGLNGNRVNKAVVVNKNVITSAGPATAI
LFGLELAKKLCGDEIYQKLYEGMLLPLTK
>Mature_188_residues
SKKVLIPLAQGFEEAEFIGIVDVLKRARELNPDLEVIIASLNSELLVKGANGISIKADCSIESVDIENLDAIALAGGFEG
MMNLKNSNVILNIIKQLHSKNKIVAAICASPIVLNEAGVLEGEFACYPSCEVGLNGNRVNKAVVVNKNVITSAGPATAIL
FGLELAKKLCGDEIYQKLYEGMLLPLTK

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=195, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI31543380, Length=195, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI87081736, Length=181, Percent_Identity=33.1491712707182, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17531319, Length=192, Percent_Identity=33.8541666666667, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28571932, Length=189, Percent_Identity=37.037037037037, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24653499, Length=189, Percent_Identity=33.3333333333333, Blast_Score=88, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 20167; Mature: 20036

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKVLIPLAQGFEEAEFIGIVDVLKRARELNPDLEVIIASLNSELLVKGANGISIKADC
CCCEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCCHHEEEECCCCEEEEECCCCEEEEECC
SIESVDIENLDAIALAGGFEGMMNLKNSNVILNIIKQLHSKNKIVAAICASPIVLNEAGV
CEEEECCCCCCEEEEECCCHHHEECCCCHHHHHHHHHHHCCCCEEEEECCCCEEECCCCC
LEGEFACYPSCEVGLNGNRVNKAVVVNKNVITSAGPATAILFGLELAKKLCGDEIYQKLY
CCCCEEECCCCEECCCCCCCCEEEEEECCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EGMLLPLTK
CCEECCCCC
>Mature Secondary Structure 
SKKVLIPLAQGFEEAEFIGIVDVLKRARELNPDLEVIIASLNSELLVKGANGISIKADC
CCEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCCHHEEEECCCCEEEEECCCCEEEEECC
SIESVDIENLDAIALAGGFEGMMNLKNSNVILNIIKQLHSKNKIVAAICASPIVLNEAGV
CEEEECCCCCCEEEEECCCHHHEECCCCHHHHHHHHHHHCCCCEEEEECCCCEEECCCCC
LEGEFACYPSCEVGLNGNRVNKAVVVNKNVITSAGPATAILFGLELAKKLCGDEIYQKLY
CCCCEEECCCCEECCCCCCCCEEEEEECCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EGMLLPLTK
CCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]