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The map label for this gene is pheS [H]

Identifier: 153952279

GI number: 153952279

Start: 811071

End: 812063

Strand: Direct

Name: pheS [H]

Synonym: JJD26997_0916

Alternate gene names: 153952279

Gene position: 811071-812063 (Clockwise)

Preceding gene: 153951347

Following gene: 153952099

Centisome position: 43.96

GC content: 32.73

Gene sequence:

>993_bases
TTGCAAAATTTTATAGAACAGATTCAAAAATGTGAGAATTTAAATGATTTGGAAGCCATTAGGATTTCCGTTCTTGGAAA
AAAAGGTATTTTAACAGAAGGCTTTACAAAGCTTAAAGGGTTAGAAGATGAGACGAAAAAAGAATTTGCTGCTAAACTAA
ATGCACAAAAAGAAATATTTAATAAGGCTTATTTAGCCAAATTTAAAGATTTGGAAAATCTTGCTTTAGAAGAAAGAATG
AAACAAGATGCTTTAAATTTTAACTATTTTGATGAAAGTATTACAACAGGTGCCTTGCATCCTGTTATGAGCACTATGGA
TAAAATCATAGAGTATTTTATAGCTTTGAATTTTAGCATAGAAAAAGGGCCTTTAATAGAAGATGACTTCCATAATTTTG
AAGCGTTAAATTTACCTAAATCTCACCCCGCAAGAGATATGCAAGATACCTTTTATTTCGATGATAAAAGGCTTTTAAGA
ACACAAACTTCGCCAGTGCAAATACGGACAATGCTTGCACAAAAACCTCCTATTAGGATGATAGCCCCTGGTGCTGTATT
TAGAAGAGATTTTGATATTACGCATACTCCTATGTTTCATCAAGTTGAAGGCCTTGTGGTGGAAGAAGGGCAAAAGGTTA
GCTTTGCAAATTTAAAAAGTGCATTGGAAGATTTTTTGCGTTATATGTTTGGAGATGTGAAAGTTCGTTTTCGTCCAAGT
TTTTTCCCATTTACAGAACCTTCTGCTGAAGTTGATATTTCTTGTGTATTTTGCAAAGAAAAGGGTTGTAGAGTTTGTAA
ACATACAGGTTGGCTTGAAGTTTTAGGATGTGGAATAGTTGATCCTAATGTTTATAATTTTGTTGGTTATGAAAATGTAA
GTGGTTATGCTTTTGGATTGGGAGTAGAACGTTTTGCAATGCTTTTGCATCAAATTCCAGATTTAAGATCTTTATTTGAA
GGTGATTTGAGATTATTGGAGCAGTTTAGATGA

Upstream 100 bases:

>100_bases
GTTTGATACAATTATATCTTTAAAGTTTGGTTTTTATGCTGAATTTAAAATAGTTTTTAATAGAATTAGAACTTGAAATA
TTTTATTTAAGGTAAGAAAA

Downstream 100 bases:

>100_bases
TAATTACTAAAAGTTGGTTGAATGATTGGTTAGAACTTGAAGAAATAAGTTCAGATAAAATAGCTAAAACTTTAAACTCT
ATAGGTATAGAAGTTGATAG

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MQNFIEQIQKCENLNDLEAIRISVLGKKGILTEGFTKLKGLEDETKKEFAAKLNAQKEIFNKAYLAKFKDLENLALEERM
KQDALNFNYFDESITTGALHPVMSTMDKIIEYFIALNFSIEKGPLIEDDFHNFEALNLPKSHPARDMQDTFYFDDKRLLR
TQTSPVQIRTMLAQKPPIRMIAPGAVFRRDFDITHTPMFHQVEGLVVEEGQKVSFANLKSALEDFLRYMFGDVKVRFRPS
FFPFTEPSAEVDISCVFCKEKGCRVCKHTGWLEVLGCGIVDPNVYNFVGYENVSGYAFGLGVERFAMLLHQIPDLRSLFE
GDLRLLEQFR

Sequences:

>Translated_330_residues
MQNFIEQIQKCENLNDLEAIRISVLGKKGILTEGFTKLKGLEDETKKEFAAKLNAQKEIFNKAYLAKFKDLENLALEERM
KQDALNFNYFDESITTGALHPVMSTMDKIIEYFIALNFSIEKGPLIEDDFHNFEALNLPKSHPARDMQDTFYFDDKRLLR
TQTSPVQIRTMLAQKPPIRMIAPGAVFRRDFDITHTPMFHQVEGLVVEEGQKVSFANLKSALEDFLRYMFGDVKVRFRPS
FFPFTEPSAEVDISCVFCKEKGCRVCKHTGWLEVLGCGIVDPNVYNFVGYENVSGYAFGLGVERFAMLLHQIPDLRSLFE
GDLRLLEQFR
>Mature_330_residues
MQNFIEQIQKCENLNDLEAIRISVLGKKGILTEGFTKLKGLEDETKKEFAAKLNAQKEIFNKAYLAKFKDLENLALEERM
KQDALNFNYFDESITTGALHPVMSTMDKIIEYFIALNFSIEKGPLIEDDFHNFEALNLPKSHPARDMQDTFYFDDKRLLR
TQTSPVQIRTMLAQKPPIRMIAPGAVFRRDFDITHTPMFHQVEGLVVEEGQKVSFANLKSALEDFLRYMFGDVKVRFRPS
FFPFTEPSAEVDISCVFCKEKGCRVCKHTGWLEVLGCGIVDPNVYNFVGYENVSGYAFGLGVERFAMLLHQIPDLRSLFE
GDLRLLEQFR

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5729820, Length=274, Percent_Identity=29.1970802919708, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI4758340, Length=281, Percent_Identity=29.8932384341637, Blast_Score=113, Evalue=3e-25,
Organism=Escherichia coli, GI1788007, Length=326, Percent_Identity=50.6134969325153, Blast_Score=321, Evalue=5e-89,
Organism=Caenorhabditis elegans, GI32566635, Length=254, Percent_Identity=31.8897637795276, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI32563657, Length=288, Percent_Identity=29.8611111111111, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17508957, Length=288, Percent_Identity=29.8611111111111, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6321087, Length=366, Percent_Identity=25.9562841530055, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6325304, Length=279, Percent_Identity=27.9569892473118, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI18858079, Length=352, Percent_Identity=28.4090909090909, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17137424, Length=287, Percent_Identity=28.2229965156794, Blast_Score=104, Evalue=7e-23,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 37988; Mature: 37988

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNFIEQIQKCENLNDLEAIRISVLGKKGILTEGFTKLKGLEDETKKEFAAKLNAQKEIF
CCHHHHHHHHHCCCCCHHHHEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NKAYLAKFKDLENLALEERMKQDALNFNYFDESITTGALHPVMSTMDKIIEYFIALNFSI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
EKGPLIEDDFHNFEALNLPKSHPARDMQDTFYFDDKRLLRTQTSPVQIRTMLAQKPPIRM
CCCCCCCCCCCCCEEECCCCCCCCCCCCHHEEECCHHHHHCCCCCHHHHHHHHCCCCCEE
IAPGAVFRRDFDITHTPMFHQVEGLVVEEGQKVSFANLKSALEDFLRYMFGDVKVRFRPS
ECCCHHHHCCCCCCCCCHHHHHCCEEECCCCEEHHHHHHHHHHHHHHHHHCCEEEEEECC
FFPFTEPSAEVDISCVFCKEKGCRVCKHTGWLEVLGCGIVDPNVYNFVGYENVSGYAFGL
CCCCCCCCCCEEEEEEEECCCCCHHHHCCCHHHHHCCCCCCCCCEEECCCCCCCCEEECC
GVERFAMLLHQIPDLRSLFEGDLRLLEQFR
CHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQNFIEQIQKCENLNDLEAIRISVLGKKGILTEGFTKLKGLEDETKKEFAAKLNAQKEIF
CCHHHHHHHHHCCCCCHHHHEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NKAYLAKFKDLENLALEERMKQDALNFNYFDESITTGALHPVMSTMDKIIEYFIALNFSI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
EKGPLIEDDFHNFEALNLPKSHPARDMQDTFYFDDKRLLRTQTSPVQIRTMLAQKPPIRM
CCCCCCCCCCCCCEEECCCCCCCCCCCCHHEEECCHHHHHCCCCCHHHHHHHHCCCCCEE
IAPGAVFRRDFDITHTPMFHQVEGLVVEEGQKVSFANLKSALEDFLRYMFGDVKVRFRPS
ECCCHHHHCCCCCCCCCHHHHHCCEEECCCCEEHHHHHHHHHHHHHHHHHCCEEEEEECC
FFPFTEPSAEVDISCVFCKEKGCRVCKHTGWLEVLGCGIVDPNVYNFVGYENVSGYAFGL
CCCCCCCCCCEEEEEEEECCCCCHHHHCCCHHHHHCCCCCCCCCEEECCCCCCCCEEECC
GVERFAMLLHQIPDLRSLFEGDLRLLEQFR
CHHHHHHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA