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The map label for this gene is rnr [H]

Identifier: 153951181

GI number: 153951181

Start: 1208404

End: 1210338

Strand: Direct

Name: rnr [H]

Synonym: JJD26997_1368

Alternate gene names: 153951181

Gene position: 1208404-1210338 (Clockwise)

Preceding gene: 153951089

Following gene: 153951750

Centisome position: 65.49

GC content: 32.87

Gene sequence:

>1935_bases
GTGAAAGAATTTTTAAACAGTCTTAGTTATGGCATCAGTTCTCACGAAGTAAGCAATGAATTTAAACAAATTTTAAGAGA
GCTTTTAGCCAATCATATCATCAAAGAACACAAAAACAAATACTATCTTAACAATGGCTTTGCCTTTGGAATACTCGATA
TTTCAAGTAAAGGCACAGGTTTTTTACAATGCTTTGATAAAAGTTTTAAAAAAGATCTTTTAATAGAAAACAAAAATCTA
AAAGGCGCAAACTATAAAGATATAGTCGCAGTAAAGCTTTTACCTTTAAAGAAAAAACGCCCCAGTGCAAAGGTGATTTT
GGTTTTAAAAAAAGCCAATGAAACTTCTTTAGTGATCACCAAAAGGTATGGCGAAGCCGTGCTTGGAATGAATATCAAAA
CAGGATTAAGCACTGCCTTAAAAGCTTCTCAAAAATCCTTAAAAGCACTGCCTTTAGGGACAATTTTAAAAATAGAAAAT
GAAAATAACAACATCATAGAAGTTTTAGGGCATATCGATGATGAAAGCGTAGATGAAAAAATCTCTTTAGCCCTTTTCAA
TAAAAACAACGAATTTAGCGACGCTTGCATTAAAGAAGCTCTAGCAAACGGAGATAGCGTTGATGCGAGTATGTATGAAA
ACCGCATGGATTTAAGAGCTTTGCCTTTTTGCACCATAGATCCCATACATGCAAAAGATTTTGATGATGCGATTTATTTT
GACACCCAAAAACGAGAAATTTATGTAGCTATTGCTGATGTTAGCGAATATGTTTATGCTTATAGCGCTATAGATAAAGA
AGCAAGAAATCGTGGATTTTCTATTTATTTTCCACATATTGCTATACCTATGCTACCTCGTCCTTTAAGTGAAAATATCT
GTTCTTTAAAACCTCATTTAGATCGCCTAGTGTATTGTTTTAAAATCACACTCGATCATGACAATAAAGTCATCAAAGAA
GAACTTTTTGAAGGTATTATCAACTCAAAACGCCGTTTTAACTACGATGAAGTCGATGAAATTTTAGTGCAAAAGCCTGA
TTTAAAAGAGCTTTCATGGATTTATGAACTTTTTGAAATCACAAAAAATTTACGCAAAATGCGTCTTAAAAATGCCTTTG
AATTTCGCACCGAAGAATTAAAAATGAATTTAGATGAAAATTTAAGTCTAAAAAGCACAGTTTTTGAAAAAGACACGCCT
TCACATAATTTGATCGAAGATTGTATGCTTTTAGCCAATAAAGCCGCAGCAAAACTCATAGATATAGGTATCTTTAGAAA
TCACTTAAGCGCTGATGCAAGAAAAATCGATAAACTTTTAAATGAATTACGCGAACTAGGCATCGATATGAATTTCAAAG
CCAATCTTCCTGAACTCATACGCGACATACAAGCTTTAGCCGATGAGTTAAATTTAAGAGCAGAAGTAGATAAACTCATC
ATCAAAGCACAAAAAAAAGCAGAATATTCCAGTATAAATGCGGGGCATTTTGGCTTAGGTTTTGATAAATACTCACATTT
TACAAGCCCTATAAGAAGGTATTCTGATCTTATTTTACACAGACTTTTAAAAGCCAAACAAAAAAACGATGAAAAACTTT
TTAACTATCTGCTTTTAAACATAGAAAGCACTTGCGAGAGTCTTAGCACGCTTGAAAGAGAAGCGGATAAGGTTGCTTTT
GATTTTATGGATAGAAAATTTGCTAGATGGGCAGCTAAAAATACAGGCAAAAAATTTAAAGCTTTAGTTGTGCAAAATGA
TGGAGTTTGCATAGCTAAACTAGATGATGAAATCAAAGGAGCGGATATCATCCTTTATGATACGCGTGTGAATTTGCTAG
AAAGTGTTGAAGTACAAATCATGGAAGCGGATATAATTATGGCAAAAATTCATGCCAAAATCACCCAAAAACTTACAAAG
GAAGAAAATGTATAA

Upstream 100 bases:

>100_bases
CAAAAATTAAAGGTGTTATTATAGCAATTAAAGTATAAATTTCATATTTTTTTTATAAACTTTATGTAAGAATTTTACAA
AAAATCATAAAGTATCAAAA

Downstream 100 bases:

>100_bases
AAAAGAGCTTCAAACCCTACTTTCTAAAGATTCAATACCCAATTTTTTCTTTCTTTATGGAGCAGATAATTTTCAAAGCG
AACTTTATGCTGAATTCATA

Product: RNB-like protein

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 644; Mature: 644

Protein sequence:

>644_residues
MKEFLNSLSYGISSHEVSNEFKQILRELLANHIIKEHKNKYYLNNGFAFGILDISSKGTGFLQCFDKSFKKDLLIENKNL
KGANYKDIVAVKLLPLKKKRPSAKVILVLKKANETSLVITKRYGEAVLGMNIKTGLSTALKASQKSLKALPLGTILKIEN
ENNNIIEVLGHIDDESVDEKISLALFNKNNEFSDACIKEALANGDSVDASMYENRMDLRALPFCTIDPIHAKDFDDAIYF
DTQKREIYVAIADVSEYVYAYSAIDKEARNRGFSIYFPHIAIPMLPRPLSENICSLKPHLDRLVYCFKITLDHDNKVIKE
ELFEGIINSKRRFNYDEVDEILVQKPDLKELSWIYELFEITKNLRKMRLKNAFEFRTEELKMNLDENLSLKSTVFEKDTP
SHNLIEDCMLLANKAAAKLIDIGIFRNHLSADARKIDKLLNELRELGIDMNFKANLPELIRDIQALADELNLRAEVDKLI
IKAQKKAEYSSINAGHFGLGFDKYSHFTSPIRRYSDLILHRLLKAKQKNDEKLFNYLLLNIESTCESLSTLEREADKVAF
DFMDRKFARWAAKNTGKKFKALVVQNDGVCIAKLDDEIKGADIILYDTRVNLLESVEVQIMEADIIMAKIHAKITQKLTK
EENV

Sequences:

>Translated_644_residues
MKEFLNSLSYGISSHEVSNEFKQILRELLANHIIKEHKNKYYLNNGFAFGILDISSKGTGFLQCFDKSFKKDLLIENKNL
KGANYKDIVAVKLLPLKKKRPSAKVILVLKKANETSLVITKRYGEAVLGMNIKTGLSTALKASQKSLKALPLGTILKIEN
ENNNIIEVLGHIDDESVDEKISLALFNKNNEFSDACIKEALANGDSVDASMYENRMDLRALPFCTIDPIHAKDFDDAIYF
DTQKREIYVAIADVSEYVYAYSAIDKEARNRGFSIYFPHIAIPMLPRPLSENICSLKPHLDRLVYCFKITLDHDNKVIKE
ELFEGIINSKRRFNYDEVDEILVQKPDLKELSWIYELFEITKNLRKMRLKNAFEFRTEELKMNLDENLSLKSTVFEKDTP
SHNLIEDCMLLANKAAAKLIDIGIFRNHLSADARKIDKLLNELRELGIDMNFKANLPELIRDIQALADELNLRAEVDKLI
IKAQKKAEYSSINAGHFGLGFDKYSHFTSPIRRYSDLILHRLLKAKQKNDEKLFNYLLLNIESTCESLSTLEREADKVAF
DFMDRKFARWAAKNTGKKFKALVVQNDGVCIAKLDDEIKGADIILYDTRVNLLESVEVQIMEADIIMAKIHAKITQKLTK
EENV
>Mature_644_residues
MKEFLNSLSYGISSHEVSNEFKQILRELLANHIIKEHKNKYYLNNGFAFGILDISSKGTGFLQCFDKSFKKDLLIENKNL
KGANYKDIVAVKLLPLKKKRPSAKVILVLKKANETSLVITKRYGEAVLGMNIKTGLSTALKASQKSLKALPLGTILKIEN
ENNNIIEVLGHIDDESVDEKISLALFNKNNEFSDACIKEALANGDSVDASMYENRMDLRALPFCTIDPIHAKDFDDAIYF
DTQKREIYVAIADVSEYVYAYSAIDKEARNRGFSIYFPHIAIPMLPRPLSENICSLKPHLDRLVYCFKITLDHDNKVIKE
ELFEGIINSKRRFNYDEVDEILVQKPDLKELSWIYELFEITKNLRKMRLKNAFEFRTEELKMNLDENLSLKSTVFEKDTP
SHNLIEDCMLLANKAAAKLIDIGIFRNHLSADARKIDKLLNELRELGIDMNFKANLPELIRDIQALADELNLRAEVDKLI
IKAQKKAEYSSINAGHFGLGFDKYSHFTSPIRRYSDLILHRLLKAKQKNDEKLFNYLLLNIESTCESLSTLEREADKVAF
DFMDRKFARWAAKNTGKKFKALVVQNDGVCIAKLDDEIKGADIILYDTRVNLLESVEVQIMEADIIMAKIHAKITQKLTK
EENV

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=528, Percent_Identity=25.5681818181818, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI190014625, Length=383, Percent_Identity=27.6762402088773, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI134288890, Length=376, Percent_Identity=28.9893617021277, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI19115966, Length=564, Percent_Identity=26.9503546099291, Blast_Score=126, Evalue=7e-29,
Organism=Homo sapiens, GI219521928, Length=564, Percent_Identity=26.9503546099291, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI156105695, Length=136, Percent_Identity=34.5588235294118, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI156105693, Length=136, Percent_Identity=34.5588235294118, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI87082383, Length=581, Percent_Identity=30.2925989672978, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1787542, Length=627, Percent_Identity=25.518341307815, Blast_Score=149, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17553506, Length=406, Percent_Identity=29.3103448275862, Blast_Score=145, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI212645896, Length=364, Percent_Identity=30.2197802197802, Blast_Score=137, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324552, Length=337, Percent_Identity=30.2670623145401, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6320499, Length=296, Percent_Identity=25, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24649634, Length=384, Percent_Identity=28.3854166666667, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI19922976, Length=424, Percent_Identity=29.2452830188679, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24654597, Length=424, Percent_Identity=29.2452830188679, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24654592, Length=424, Percent_Identity=29.2452830188679, Blast_Score=132, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR011805 [H]

Pfam domain/function: PF00773 RNB [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 73714; Mature: 73714

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEFLNSLSYGISSHEVSNEFKQILRELLANHIIKEHKNKYYLNNGFAFGILDISSKGTG
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEECCCCCH
FLQCFDKSFKKDLLIENKNLKGANYKDIVAVKLLPLKKKRPSAKVILVLKKANETSLVIT
HHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEEECCCCEEEEE
KRYGEAVLGMNIKTGLSTALKASQKSLKALPLGTILKIENENNNIIEVLGHIDDESVDEK
ECCCCEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCCCCE
ISLALFNKNNEFSDACIKEALANGDSVDASMYENRMDLRALPFCTIDPIHAKDFDDAIYF
EEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCEECCCEECCCCCCCCCCCCEEE
DTQKREIYVAIADVSEYVYAYSAIDKEARNRGFSIYFPHIAIPMLPRPLSENICSLKPHL
ECCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCEEEECCEECCCCCCCHHCCHHHCCHHH
DRLVYCFKITLDHDNKVIKEELFEGIINSKRRFNYDEVDEILVQKPDLKELSWIYELFEI
HHEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
TKNLRKMRLKNAFEFRTEELKMNLDENLSLKSTVFEKDTPSHNLIEDCMLLANKAAAKLI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
DIGIFRNHLSADARKIDKLLNELRELGIDMNFKANLPELIRDIQALADELNLRAEVDKLI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
IKAQKKAEYSSINAGHFGLGFDKYSHFTSPIRRYSDLILHRLLKAKQKNDEKLFNYLLLN
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IESTCESLSTLEREADKVAFDFMDRKFARWAAKNTGKKFKALVVQNDGVCIAKLDDEIKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEECCCCCCC
ADIILYDTRVNLLESVEVQIMEADIIMAKIHAKITQKLTKEENV
CEEEEEECHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKEFLNSLSYGISSHEVSNEFKQILRELLANHIIKEHKNKYYLNNGFAFGILDISSKGTG
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEECCCCCH
FLQCFDKSFKKDLLIENKNLKGANYKDIVAVKLLPLKKKRPSAKVILVLKKANETSLVIT
HHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEEECCCCEEEEE
KRYGEAVLGMNIKTGLSTALKASQKSLKALPLGTILKIENENNNIIEVLGHIDDESVDEK
ECCCCEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCCCCE
ISLALFNKNNEFSDACIKEALANGDSVDASMYENRMDLRALPFCTIDPIHAKDFDDAIYF
EEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCEECCCEECCCCCCCCCCCCEEE
DTQKREIYVAIADVSEYVYAYSAIDKEARNRGFSIYFPHIAIPMLPRPLSENICSLKPHL
ECCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCEEEECCEECCCCCCCHHCCHHHCCHHH
DRLVYCFKITLDHDNKVIKEELFEGIINSKRRFNYDEVDEILVQKPDLKELSWIYELFEI
HHEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
TKNLRKMRLKNAFEFRTEELKMNLDENLSLKSTVFEKDTPSHNLIEDCMLLANKAAAKLI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
DIGIFRNHLSADARKIDKLLNELRELGIDMNFKANLPELIRDIQALADELNLRAEVDKLI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
IKAQKKAEYSSINAGHFGLGFDKYSHFTSPIRRYSDLILHRLLKAKQKNDEKLFNYLLLN
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IESTCESLSTLEREADKVAFDFMDRKFARWAAKNTGKKFKALVVQNDGVCIAKLDDEIKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEECCCCCCC
ADIILYDTRVNLLESVEVQIMEADIIMAKIHAKITQKLTKEENV
CEEEEEECHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]