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The map label for this gene is fabG [H]

Identifier: 153951125

GI number: 153951125

Start: 1263445

End: 1264176

Strand: Direct

Name: fabG [H]

Synonym: JJD26997_1425

Alternate gene names: 153951125

Gene position: 1263445-1264176 (Clockwise)

Preceding gene: 153952147

Following gene: 153951487

Centisome position: 68.48

GC content: 30.74

Gene sequence:

>732_bases
ATGCAAAAAGTCATTCTTATAACAGGGACAAGAAAGGGTATAGGCAAACAATTAAGCGAATATTATCTTTCTTTAGGTTA
TATAGTGTGTGGGTGTTCTAGGGGTGCTTCGAGTATAAATCATATAAATTATAGACATTTTGAACTTGATGTGAGCGATG
AAGAAAAAGTAGTTTCTATGGTTCGTGCTGTGCGCAAAGAATTTTCTCGTATAGATATATTATTAAATAATGCAGGCATT
GCTTCTATGAATCATATTTTAACCACGCCTTATAAAAGCATTAATAATATTTTTAATACTAATGTTTTTGGTACTTTTTT
ATTTACAAGAGAAGTTGCCAAAGTTATGGGTAATATTTATAAAAAAAATTATAAAAACACGAAAACCATGCCTTTTCGTA
TAGTTAATTTTACTACTGTTGCTACTCCTTTAAGACTTGAAGGTGAAGCCATATATGCAGCATCTAAAGCTGCTTTGGTT
AATTTAACTCAAGTATGTGCTAAAGAATTAAGTGAATTTGGCATCACTGTAAATGCTGTTGGCCCTACACCTGTTCCAAC
GGATTTAATTAAAAATGTTCCTCAAAATAAACTCGATATTTTATTAAATCAGCAAGCCATTAAACGCTTTGGAGAATTTG
AAGATGTGTTAAATGTTATTGAGTTTTTTCTTGATGAAAAAAGTGGTTTTATAACCTCACAAGTAGTTTATTTGGGTGGA
ATCAATGCATAA

Upstream 100 bases:

>100_bases
ATAACTCTTGCAGATGAAAAAATGATGAGTTTAAGAAACTCTCCTTTTAAAGATGTTCAAACACTAGCTCAATATATAGC
AAGTCAAATTAAGGTATAAA

Downstream 100 bases:

>100_bases
TTTAAATTTTTCTCATCCTTTTTTAAACAAACTTATAGCTTATAAAGATTTAAATTGTTTGATTTATAAAGATAAAACTT
ATTCTTATTTGGAACTTTTA

Product: NAD dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MQKVILITGTRKGIGKQLSEYYLSLGYIVCGCSRGASSINHINYRHFELDVSDEEKVVSMVRAVRKEFSRIDILLNNAGI
ASMNHILTTPYKSINNIFNTNVFGTFLFTREVAKVMGNIYKKNYKNTKTMPFRIVNFTTVATPLRLEGEAIYAASKAALV
NLTQVCAKELSEFGITVNAVGPTPVPTDLIKNVPQNKLDILLNQQAIKRFGEFEDVLNVIEFFLDEKSGFITSQVVYLGG
INA

Sequences:

>Translated_243_residues
MQKVILITGTRKGIGKQLSEYYLSLGYIVCGCSRGASSINHINYRHFELDVSDEEKVVSMVRAVRKEFSRIDILLNNAGI
ASMNHILTTPYKSINNIFNTNVFGTFLFTREVAKVMGNIYKKNYKNTKTMPFRIVNFTTVATPLRLEGEAIYAASKAALV
NLTQVCAKELSEFGITVNAVGPTPVPTDLIKNVPQNKLDILLNQQAIKRFGEFEDVLNVIEFFLDEKSGFITSQVVYLGG
INA
>Mature_243_residues
MQKVILITGTRKGIGKQLSEYYLSLGYIVCGCSRGASSINHINYRHFELDVSDEEKVVSMVRAVRKEFSRIDILLNNAGI
ASMNHILTTPYKSINNIFNTNVFGTFLFTREVAKVMGNIYKKNYKNTKTMPFRIVNFTTVATPLRLEGEAIYAASKAALV
NLTQVCAKELSEFGITVNAVGPTPVPTDLIKNVPQNKLDILLNQQAIKRFGEFEDVLNVIEFFLDEKSGFITSQVVYLGG
INA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=26.984126984127, Blast_Score=97, Evalue=9e-21,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=26.8292682926829, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=27.1604938271605, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI109715829, Length=201, Percent_Identity=26.3681592039801, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4758504, Length=251, Percent_Identity=25.0996015936255, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=29.0983606557377, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=30, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=27.1255060728745, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788459, Length=256, Percent_Identity=25.78125, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=23.9382239382239, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=26.5625, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=23.2931726907631, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=22.8915662650602, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=25.4032258064516, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786701, Length=237, Percent_Identity=27.8481012658228, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=25.3061224489796, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=30.8, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=202, Percent_Identity=28.7128712871287, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=28.2945736434109, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=23.9837398373984, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=23.921568627451, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=28.0487804878049, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=26.1044176706827, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=27.8884462151394, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=25.2, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=28.2868525896414, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=27.710843373494, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571387, Length=212, Percent_Identity=26.8867924528302, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24648944, Length=200, Percent_Identity=27.5, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737361, Length=204, Percent_Identity=27.9411764705882, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116007236, Length=234, Percent_Identity=24.3589743589744, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27101; Mature: 27101

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKVILITGTRKGIGKQLSEYYLSLGYIVCGCSRGASSINHINYRHFELDVSDEEKVVSM
CCEEEEEECCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEEEECCCCHHHHHHH
VRAVRKEFSRIDILLNNAGIASMNHILTTPYKSINNIFNTNVFGTFLFTREVAKVMGNIY
HHHHHHHHHHEEEEEECCCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KKNYKNTKTMPFRIVNFTTVATPLRLEGEAIYAASKAALVNLTQVCAKELSEFGITVNAV
HHCCCCCCCCCEEEEEEEEECCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHCCEEEEEC
GPTPVPTDLIKNVPQNKLDILLNQQAIKRFGEFEDVLNVIEFFLDEKSGFITSQVVYLGG
CCCCCCHHHHHCCCCCHHHHHCCHHHHHHHCCHHHHHHHHHHHHCCCCCCEEHEEEEECC
INA
CCC
>Mature Secondary Structure
MQKVILITGTRKGIGKQLSEYYLSLGYIVCGCSRGASSINHINYRHFELDVSDEEKVVSM
CCEEEEEECCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEEEECCCCHHHHHHH
VRAVRKEFSRIDILLNNAGIASMNHILTTPYKSINNIFNTNVFGTFLFTREVAKVMGNIY
HHHHHHHHHHEEEEEECCCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KKNYKNTKTMPFRIVNFTTVATPLRLEGEAIYAASKAALVNLTQVCAKELSEFGITVNAV
HHCCCCCCCCCEEEEEEEEECCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHCCEEEEEC
GPTPVPTDLIKNVPQNKLDILLNQQAIKRFGEFEDVLNVIEFFLDEKSGFITSQVVYLGG
CCCCCCHHHHHCCCCCHHHHHCCHHHHHHHCCHHHHHHHHHHHHCCCCCCEEHEEEEECC
INA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1556094; 8905232; 9278503; 1314802 [H]