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The map label for this gene is sstT [H]

Identifier: 153937781

GI number: 153937781

Start: 3520222

End: 3521397

Strand: Direct

Name: sstT [H]

Synonym: CLC_3351

Alternate gene names: 153937781

Gene position: 3520222-3521397 (Clockwise)

Preceding gene: 153937845

Following gene: 153934710

Centisome position: 93.61

GC content: 32.82

Gene sequence:

>1176_bases
ATGAAAAAATTAGGATTAATACCCAAAATTATTATAGCCATCATTTTAGGTATTCTAATAGGTAGCTTTACACCAATTCC
TGTAATACGCATATTTAGAACTTTTAGCTCCATATTTGGAGAATTTCTAGGATTCCTTATACCTTTAATAATTCTGGGAT
TCATTGTTGCCGGTATCGCTGAACTTGGACAAGGTGCTGGTAAGCTATTAGGAATTACTGTTGGTTTAGCTTATTTATTC
ACACTAATATCTGGTTTTTCTGCTTTATTAGTTGGTAGAACATTATTGCCATCAATTATTACTAGTGCCACTCATGTAGA
AAAAGCTAAAAAAGCTCTGGATCCTTTCTTTGAAGTTAAAATTCCACCAATGATGGACGTTATGACTGCACTTATATTTG
CTTTTATATTAGGGTTAGGTATTGCAAAGATACAAAATAAAACTCTAAAGGATGTAGCTATAGGATTCCAAGAAATAATA
ACAAAAGTCATCGAAAACGTTGTTATACCACTACTTCCACTTCACATATTAGGCATATTCGCTAACTTAGCTTATACTGG
TGAAGTATCAACTGTTTTAAAAGTATTTTGGAAGGTATTTATAATTATACTTATTTTACATTGGATTATACTAATTTTCC
AATTCTCAGTAGGTGGATCTATTGCTGGTAAAAATCCTTTTAAATCATTAAAAATCCAAATTAAAGGATATCTTACCGCT
TTAGGAACTCAATCTTCTGCTGCAACTATTCCTATTAATATTCAATGTTCAGAACAAATAGGAATTAGCAAAGGTATAAG
AGATTTTGTTATTCCTTTATGTGCAACTGTCCATTTATCAGGAAGTACTATTACTTTAACTATATGTGCACTATCTGTTA
TGCTGTTAAACGGTATGCCTATAAGTATGTCTCAGATGGCTGGATTTATAGCTATGCTAGGTGTAACTATGGTAGCAGCT
CCTGGTGTTCCTGGAGGTGCAGTAATGGCAGCTCTTGGCATACTTCAATCAATATTAGGCTTTAATGAGGCTTTACTTGG
TTTAATGATTGCTCTATACATTGCTCAAGATAGCTTTGGTACTGCCTGTAATGTATCTGGGGATCAGGCCGTAGCAATGA
TTGTGGATGCTATACAAAAAAATCGGATAAAAAGCATAATAAAAATATTTAACTAA

Upstream 100 bases:

>100_bases
ATTCACTAATATCATATATAATTTAAAAATTAATTGCATATTATTATATAATTAGTAATTGTATTAATCACTTAAATATA
TAAAAAGGGGGAGAATATCA

Downstream 100 bases:

>100_bases
ACAATTTATATAAAATGGGTGTATAAAAATTTTTACTTCTATACACCCATTTTGTTAGAATAAGAGCAATTCTAGCCCTT
AAAAATACCTTTTATAAATT

Product: sodium:dicarboxylate symporter family protein

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MKKLGLIPKIIIAIILGILIGSFTPIPVIRIFRTFSSIFGEFLGFLIPLIILGFIVAGIAELGQGAGKLLGITVGLAYLF
TLISGFSALLVGRTLLPSIITSATHVEKAKKALDPFFEVKIPPMMDVMTALIFAFILGLGIAKIQNKTLKDVAIGFQEII
TKVIENVVIPLLPLHILGIFANLAYTGEVSTVLKVFWKVFIIILILHWIILIFQFSVGGSIAGKNPFKSLKIQIKGYLTA
LGTQSSAATIPINIQCSEQIGISKGIRDFVIPLCATVHLSGSTITLTICALSVMLLNGMPISMSQMAGFIAMLGVTMVAA
PGVPGGAVMAALGILQSILGFNEALLGLMIALYIAQDSFGTACNVSGDQAVAMIVDAIQKNRIKSIIKIFN

Sequences:

>Translated_391_residues
MKKLGLIPKIIIAIILGILIGSFTPIPVIRIFRTFSSIFGEFLGFLIPLIILGFIVAGIAELGQGAGKLLGITVGLAYLF
TLISGFSALLVGRTLLPSIITSATHVEKAKKALDPFFEVKIPPMMDVMTALIFAFILGLGIAKIQNKTLKDVAIGFQEII
TKVIENVVIPLLPLHILGIFANLAYTGEVSTVLKVFWKVFIIILILHWIILIFQFSVGGSIAGKNPFKSLKIQIKGYLTA
LGTQSSAATIPINIQCSEQIGISKGIRDFVIPLCATVHLSGSTITLTICALSVMLLNGMPISMSQMAGFIAMLGVTMVAA
PGVPGGAVMAALGILQSILGFNEALLGLMIALYIAQDSFGTACNVSGDQAVAMIVDAIQKNRIKSIIKIFN
>Mature_391_residues
MKKLGLIPKIIIAIILGILIGSFTPIPVIRIFRTFSSIFGEFLGFLIPLIILGFIVAGIAELGQGAGKLLGITVGLAYLF
TLISGFSALLVGRTLLPSIITSATHVEKAKKALDPFFEVKIPPMMDVMTALIFAFILGLGIAKIQNKTLKDVAIGFQEII
TKVIENVVIPLLPLHILGIFANLAYTGEVSTVLKVFWKVFIIILILHWIILIFQFSVGGSIAGKNPFKSLKIQIKGYLTA
LGTQSSAATIPINIQCSEQIGISKGIRDFVIPLCATVHLSGSTITLTICALSVMLLNGMPISMSQMAGFIAMLGVTMVAA
PGVPGGAVMAALGILQSILGFNEALLGLMIALYIAQDSFGTACNVSGDQAVAMIVDAIQKNRIKSIIKIFN

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI4827012, Length=257, Percent_Identity=26.0700389105058, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI169790839, Length=266, Percent_Identity=25.5639097744361, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI40254478, Length=167, Percent_Identity=29.3413173652695, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI21314632, Length=162, Percent_Identity=32.0987654320988, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI66773030, Length=302, Percent_Identity=25.1655629139073, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71983106, Length=272, Percent_Identity=24.6323529411765, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71983099, Length=267, Percent_Identity=25.0936329588015, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193206505, Length=261, Percent_Identity=28.3524904214559, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17537407, Length=255, Percent_Identity=26.6666666666667, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71996953, Length=165, Percent_Identity=24.8484848484848, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24583025, Length=164, Percent_Identity=26.219512195122, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17137668, Length=164, Percent_Identity=26.219512195122, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24583023, Length=164, Percent_Identity=26.219512195122, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR023025 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 41552; Mature: 41552

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CEECCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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CEECCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA