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The map label for this gene is yisV [H]

Identifier: 153937629

GI number: 153937629

Start: 542857

End: 544308

Strand: Direct

Name: yisV [H]

Synonym: CLC_0535

Alternate gene names: 153937629

Gene position: 542857-544308 (Clockwise)

Preceding gene: 153935148

Following gene: 153936635

Centisome position: 14.44

GC content: 26.03

Gene sequence:

>1452_bases
ATGTTATTTGATATAAAGTTAGATAAAAATTCACCAGTATATATACAGATAAGTGATTATATAAAATCTATGATATTAAA
GGGAATGATAAGAAAAGATGAAAAATTACCATCAACTAGAGAGCTAGCTTCTATGCTTAAGGTTAGTAGGAATACTATTA
TATCTGCTTATGAGTTTTTAGAGGATGATGGATTTATATATATAAGAAAAGGTAAGGGAGCCTTTGTTTCTAATGTGAAT
ATTCATGTTGAAGAAAAATGGACAGTTAATTGGGAAAAGAATATAAATGATTATGCTAAGAAAGCCGAAAATTTAGATAT
TATAAAACATGAAATACCTTGGGAAAAGGGCATGATATCTTTTAAAAGTATTTCTCCAGATGAGAATTTATTTGATTTAG
AGGAATTTAAAAAAGCTTTTTTAAATAGATTTTCATTAGAAGGAGAGAAAATATTAAATTACGGTTATGCTATAGGATAT
AGGGATTTAATAAATTATATTATGAAGTATATGAAAAATAAGGGAGTGGACACATCAAATAAAAAGATATTAATAACTAA
TGGCTTTACAGAAGGCTTTGATATTGTATTGTCTTCTTTAATAAAAAAAGGGGATAAGATATTATGTGAAAACCCTACTC
ATAATACAGCTATAAAAATAATGAAGATGCATGATATTGAAATTGTAGGCATCGATATGGACAAAGACGGTATAAATATA
GATAAATTAAAAGAAACTATAGGTAAAAACAATATAAAGTTAGCTTATTTGGTACCTTCTTATCATAATCCTACAGGTAT
AGTTATGAGTCCAGAAAAAAGAATAAAAATATACAATATACTAAAAGATAATAACATACCTATAATAGAAGATGGATTTA
ACGAAGAACTAAGATATTCTGGTGATCATGTATCTCCTATGATTGCTTTTTCTGGTAAGGGTAATAGCATTATTTATATA
GGAAGCTTTTCAAAGGTACTTTTCCCTGGAATAAGAATAGGTTGGGTATTAGGAGATGAAAAACTTATAGACTATTTAGA
AAGTGTAAAAAGAAGCAGAAATATTCACACATCATTTTTAGATCAGGCTATATTGTATGAATATTTAAAGAGTGGAAATT
TTGAAAAATATATTAAAAAAGCTAGGAAAATATATAAAGAAAAATATGAATTTGCTTTAGAATGTGCTAAAAAATATATA
CCTGCAGAATATATTACAGGAGAAGGTGGGCTTCATATATTTATAAAATTAAAAAATATAAAATCAAGAGAATTATTAAA
AGAGTGTTGCAAAAGGGGAGTAATTTTTACTCCAGGAGACATATTCTATGTAGATAACAAAGGAGAAGACACTTTTAGAT
TAGGTATATCTAGAGTTTCTTTAGAAGAAATAGAAAAAGGCTTTAAAATTATAGGAAATTCAGCAAAAAAACTTATAAAT
AATTATATTTAG

Upstream 100 bases:

>100_bases
CGAAATGAGTTGATTTATAAGGTGATTTTTATATTTGTGGAATTAAAATTAAATATATCTTCAGATTTGATTTGTACAAT
GAGCTTTTGGGAGGAATTTT

Downstream 100 bases:

>100_bases
TGAAAATTTTGTTAAATTAATGTATAATATTAATAAAAATATTAAAATGGTGGTGAGTTTATGAAAAAAGGATTGAGAAA
TACCCTTATAGTAGTAGGGA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MLFDIKLDKNSPVYIQISDYIKSMILKGMIRKDEKLPSTRELASMLKVSRNTIISAYEFLEDDGFIYIRKGKGAFVSNVN
IHVEEKWTVNWEKNINDYAKKAENLDIIKHEIPWEKGMISFKSISPDENLFDLEEFKKAFLNRFSLEGEKILNYGYAIGY
RDLINYIMKYMKNKGVDTSNKKILITNGFTEGFDIVLSSLIKKGDKILCENPTHNTAIKIMKMHDIEIVGIDMDKDGINI
DKLKETIGKNNIKLAYLVPSYHNPTGIVMSPEKRIKIYNILKDNNIPIIEDGFNEELRYSGDHVSPMIAFSGKGNSIIYI
GSFSKVLFPGIRIGWVLGDEKLIDYLESVKRSRNIHTSFLDQAILYEYLKSGNFEKYIKKARKIYKEKYEFALECAKKYI
PAEYITGEGGLHIFIKLKNIKSRELLKECCKRGVIFTPGDIFYVDNKGEDTFRLGISRVSLEEIEKGFKIIGNSAKKLIN
NYI

Sequences:

>Translated_483_residues
MLFDIKLDKNSPVYIQISDYIKSMILKGMIRKDEKLPSTRELASMLKVSRNTIISAYEFLEDDGFIYIRKGKGAFVSNVN
IHVEEKWTVNWEKNINDYAKKAENLDIIKHEIPWEKGMISFKSISPDENLFDLEEFKKAFLNRFSLEGEKILNYGYAIGY
RDLINYIMKYMKNKGVDTSNKKILITNGFTEGFDIVLSSLIKKGDKILCENPTHNTAIKIMKMHDIEIVGIDMDKDGINI
DKLKETIGKNNIKLAYLVPSYHNPTGIVMSPEKRIKIYNILKDNNIPIIEDGFNEELRYSGDHVSPMIAFSGKGNSIIYI
GSFSKVLFPGIRIGWVLGDEKLIDYLESVKRSRNIHTSFLDQAILYEYLKSGNFEKYIKKARKIYKEKYEFALECAKKYI
PAEYITGEGGLHIFIKLKNIKSRELLKECCKRGVIFTPGDIFYVDNKGEDTFRLGISRVSLEEIEKGFKIIGNSAKKLIN
NYI
>Mature_483_residues
MLFDIKLDKNSPVYIQISDYIKSMILKGMIRKDEKLPSTRELASMLKVSRNTIISAYEFLEDDGFIYIRKGKGAFVSNVN
IHVEEKWTVNWEKNINDYAKKAENLDIIKHEIPWEKGMISFKSISPDENLFDLEEFKKAFLNRFSLEGEKILNYGYAIGY
RDLINYIMKYMKNKGVDTSNKKILITNGFTEGFDIVLSSLIKKGDKILCENPTHNTAIKIMKMHDIEIVGIDMDKDGINI
DKLKETIGKNNIKLAYLVPSYHNPTGIVMSPEKRIKIYNILKDNNIPIIEDGFNEELRYSGDHVSPMIAFSGKGNSIIYI
GSFSKVLFPGIRIGWVLGDEKLIDYLESVKRSRNIHTSFLDQAILYEYLKSGNFEKYIKKARKIYKEKYEFALECAKKYI
PAEYITGEGGLHIFIKLKNIKSRELLKECCKRGVIFTPGDIFYVDNKGEDTFRLGISRVSLEEIEKGFKIIGNSAKKLIN
NYI

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=397, Percent_Identity=25.1889168765743, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI33469970, Length=397, Percent_Identity=25.1889168765743, Blast_Score=123, Evalue=4e-28,
Organism=Escherichia coli, GI1787710, Length=467, Percent_Identity=23.1263383297645, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1790797, Length=469, Percent_Identity=22.8144989339019, Blast_Score=135, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6321236, Length=393, Percent_Identity=24.1730279898219, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6321000, Length=249, Percent_Identity=27.710843373494, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21356535, Length=389, Percent_Identity=24.1645244215938, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 55659; Mature: 55659

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFDIKLDKNSPVYIQISDYIKSMILKGMIRKDEKLPSTRELASMLKVSRNTIISAYEFL
CEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
EDDGFIYIRKGKGAFVSNVNIHVEEKWTVNWEKNINDYAKKAENLDIIKHEIPWEKGMIS
CCCCEEEEECCCCCEEEEEEEEEEEEEEEEHHCCCHHHHHHCCCCCEEEECCCCCCCCEE
FKSISPDENLFDLEEFKKAFLNRFSLEGEKILNYGYAIGYRDLINYIMKYMKNKGVDTSN
EECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
KKILITNGFTEGFDIVLSSLIKKGDKILCENPTHNTAIKIMKMHDIEIVGIDMDKDGINI
CEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEECEEEEEEECCCCCCCH
DKLKETIGKNNIKLAYLVPSYHNPTGIVMSPEKRIKIYNILKDNNIPIIEDGFNEELRYS
HHHHHHHCCCCEEEEEEECCCCCCCCEEECCCCCEEEEEEEECCCCCEEECCCCCCHHCC
GDHVSPMIAFSGKGNSIIYIGSFSKVLFPGIRIGWVLGDEKLIDYLESVKRSRNIHTSFL
CCCCCEEEEECCCCCEEEEEECCHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHH
DQAILYEYLKSGNFEKYIKKARKIYKEKYEFALECAKKYIPAEYITGEGGLHIFIKLKNI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEECCC
KSRELLKECCKRGVIFTPGDIFYVDNKGEDTFRLGISRVSLEEIEKGFKIIGNSAKKLIN
CHHHHHHHHHHCCCEECCCCEEEEECCCCCEEEECHHHCCHHHHHHHHHHHCHHHHHHHH
NYI
HCC
>Mature Secondary Structure
MLFDIKLDKNSPVYIQISDYIKSMILKGMIRKDEKLPSTRELASMLKVSRNTIISAYEFL
CEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
EDDGFIYIRKGKGAFVSNVNIHVEEKWTVNWEKNINDYAKKAENLDIIKHEIPWEKGMIS
CCCCEEEEECCCCCEEEEEEEEEEEEEEEEHHCCCHHHHHHCCCCCEEEECCCCCCCCEE
FKSISPDENLFDLEEFKKAFLNRFSLEGEKILNYGYAIGYRDLINYIMKYMKNKGVDTSN
EECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
KKILITNGFTEGFDIVLSSLIKKGDKILCENPTHNTAIKIMKMHDIEIVGIDMDKDGINI
CEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEECEEEEEEECCCCCCCH
DKLKETIGKNNIKLAYLVPSYHNPTGIVMSPEKRIKIYNILKDNNIPIIEDGFNEELRYS
HHHHHHHCCCCEEEEEEECCCCCCCCEEECCCCCEEEEEEEECCCCCEEECCCCCCHHCC
GDHVSPMIAFSGKGNSIIYIGSFSKVLFPGIRIGWVLGDEKLIDYLESVKRSRNIHTSFL
CCCCCEEEEECCCCCEEEEEECCHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHH
DQAILYEYLKSGNFEKYIKKARKIYKEKYEFALECAKKYIPAEYITGEGGLHIFIKLKNI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEECCC
KSRELLKECCKRGVIFTPGDIFYVDNKGEDTFRLGISRVSLEEIEKGFKIIGNSAKKLIN
CHHHHHHHHHHCCCEECCCCEEEEECCCCCEEEECHHHCCHHHHHHHHHHHCHHHHHHHH
NYI
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]