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The map label for this gene is fnr [H]

Identifier: 153937427

GI number: 153937427

Start: 1028311

End: 1029000

Strand: Direct

Name: fnr [H]

Synonym: CLC_1011

Alternate gene names: 153937427

Gene position: 1028311-1029000 (Clockwise)

Preceding gene: 153935290

Following gene: 153934673

Centisome position: 27.34

GC content: 25.22

Gene sequence:

>690_bases
ATGAACAGTTCAATAAAATATAAATTAAAGGATTTAGAGATATTTTCTAGTCTTAAAAATGATGAATTAGATATGTTAGC
TAATAAATCTAGAGTAATAGATTTAAAAAAAGGAGAAATCTTATTTTATGAAAGAGATTCTGTAGATAATGTATATATAG
TATTAGAAGGAAAAGTTACTTTGTATAGAATTTCAGAAAATGGACAAAAAAGAGTAGTATTTATAATAGATAAGGGGAAA
TTTATAAATGAAATTATACTAGATAAGAAGCCAGCGTCTATATGCTGTGAGGGATTTGAAAACAGTAAAGTTTTATCAAT
TAAAAGAAATGATTTATTATATATAATGGGTGGAAATTTTGAATTTACCCAAGAAGTGATGTTTTCAATGACTAATAAAA
TAAGAAGGATGTATAGACAATTAAAAAATACAGTACCTCTTAAAGTAGAAAAAAGAGTAGCGGCTAAGCTTTGGAAATTG
GCTAAAGATTATGGTGAGTATGGAAAAAATGGAGAAGTCATAAAGCTAAATATAACAGTTACTTATCTCTCAGAAATGTT
AGGAAGTTCAAGGGAAACTATATCTAGAGCACTGAAAGAGTTAAAAAATAAAGAACTTATATATTATGAAGGTAAAAAAA
TAATAATTAAAGATAGAGATAAATTATCAAAGTTTTTTAAGGGTATGTGA

Upstream 100 bases:

>100_bases
AATTTGTTTTAATGTGCAGGAATAGGAATACCAAGGTTCGCTTATAATTGAAAGCTTGCAAAACAATAAGAGAATTATAT
AAATGGGGGTATTAATTCTC

Downstream 100 bases:

>100_bases
TTTTCATCACATACTTTTTTTTGTATGCACTATAGAATAGAGTATAAGAAATAATGGAGTTATTAAAAAAAGAAAGGAGA
TGTTGGATCATGTATAGTGA

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MNSSIKYKLKDLEIFSSLKNDELDMLANKSRVIDLKKGEILFYERDSVDNVYIVLEGKVTLYRISENGQKRVVFIIDKGK
FINEIILDKKPASICCEGFENSKVLSIKRNDLLYIMGGNFEFTQEVMFSMTNKIRRMYRQLKNTVPLKVEKRVAAKLWKL
AKDYGEYGKNGEVIKLNITVTYLSEMLGSSRETISRALKELKNKELIYYEGKKIIIKDRDKLSKFFKGM

Sequences:

>Translated_229_residues
MNSSIKYKLKDLEIFSSLKNDELDMLANKSRVIDLKKGEILFYERDSVDNVYIVLEGKVTLYRISENGQKRVVFIIDKGK
FINEIILDKKPASICCEGFENSKVLSIKRNDLLYIMGGNFEFTQEVMFSMTNKIRRMYRQLKNTVPLKVEKRVAAKLWKL
AKDYGEYGKNGEVIKLNITVTYLSEMLGSSRETISRALKELKNKELIYYEGKKIIIKDRDKLSKFFKGM
>Mature_229_residues
MNSSIKYKLKDLEIFSSLKNDELDMLANKSRVIDLKKGEILFYERDSVDNVYIVLEGKVTLYRISENGQKRVVFIIDKGK
FINEIILDKKPASICCEGFENSKVLSIKRNDLLYIMGGNFEFTQEVMFSMTNKIRRMYRQLKNTVPLKVEKRVAAKLWKL
AKDYGEYGKNGEVIKLNITVTYLSEMLGSSRETISRALKELKNKELIYYEGKKIIIKDRDKLSKFFKGM

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=232, Percent_Identity=25, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 26704; Mature: 26704

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSIKYKLKDLEIFSSLKNDELDMLANKSRVIDLKKGEILFYERDSVDNVYIVLEGKVT
CCCCEEEEEHHHHHHHHCCCCCHHHHCCCCEEEEEECCEEEEEECCCCCEEEEEEECCEE
LYRISENGQKRVVFIIDKGKFINEIILDKKPASICCEGFENSKVLSIKRNDLLYIMGGNF
EEEECCCCCEEEEEEEECCCHHHHHHCCCCCHHHHHCCCCCCEEEEEECCCEEEEECCCC
EFTQEVMFSMTNKIRRMYRQLKNTVPLKVEKRVAAKLWKLAKDYGEYGKNGEVIKLNITV
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEH
TYLSEMLGSSRETISRALKELKNKELIYYEGKKIIIKDRDKLSKFFKGM
HHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCEEEEECHHHHHHHHCCC
>Mature Secondary Structure
MNSSIKYKLKDLEIFSSLKNDELDMLANKSRVIDLKKGEILFYERDSVDNVYIVLEGKVT
CCCCEEEEEHHHHHHHHCCCCCHHHHCCCCEEEEEECCEEEEEECCCCCEEEEEEECCEE
LYRISENGQKRVVFIIDKGKFINEIILDKKPASICCEGFENSKVLSIKRNDLLYIMGGNF
EEEECCCCCEEEEEEEECCCHHHHHHCCCCCHHHHHCCCCCCEEEEEECCCEEEEECCCC
EFTQEVMFSMTNKIRRMYRQLKNTVPLKVEKRVAAKLWKLAKDYGEYGKNGEVIKLNITV
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEH
TYLSEMLGSSRETISRALKELKNKELIYYEGKKIIIKDRDKLSKFFKGM
HHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCEEEEECHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]