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The map label for this gene is nirC [H]

Identifier: 153934673

GI number: 153934673

Start: 1029090

End: 1029854

Strand: Direct

Name: nirC [H]

Synonym: CLC_1012

Alternate gene names: 153934673

Gene position: 1029090-1029854 (Clockwise)

Preceding gene: 153937427

Following gene: 153934778

Centisome position: 27.37

GC content: 31.76

Gene sequence:

>765_bases
ATGTATAGTGAAGAAATTAACAAGATTAGTAATGTAGCAGAAAACAAAAGGGACTTATTAAGAAATAATAGAGTAGGCTA
TTTAGTATCTTCTGCTCTTGCGGGAATATATGTAGGCATAGGTACTATACTCATATTTACATTAGGCGGAAATTTAGAAG
CTGTTAATTCTTCTTATGTAAAGCTTATCATGGGTTTATCTTTCGGCATAGCTTTAAGTCTTGTTATTATGGCTGGATCA
GAACTTTTTACAGGAAATAATATGGTTATGGCCATAGGAACATTAAATAAGAAAACTACATGGAAGGATGCCTTAAGCAT
ATGGGGGAATAGCTTTGCAGGAAATTTAATAGGATCAATGCTTTTAGCCTTAATATTTGTTAATGCAGGATTAGCAAAAG
GATCTGTAGGTAAATTTATTTTAAAAACAGCAGAAACAAAGATGACGCTATCCCCTATGGAATTATTTTTAAGAGGCTTG
CTGTGTAATATTTTAGTTTGTTTAGCTGTATGGTGTAGTTTAAAGATGAAGGAAGAGGCGGGAAAACTTATAATGATATT
TTGGTGCTTATTTGCCTTTATATCATCAGGATTTGAACACAGTGTGGCAAATATGACTTTGTTTTCTATAGCTTTATTTA
TACCACATGGAGTTGGAATATCCGTAAATGGAATGGCATATAATTTAATTTTTGTTTCTTTAGGAAATATTATAGGCGGA
GCATTATTTGTAGGAGCAGCCTATTATAAAATATCAAAAAAATAG

Upstream 100 bases:

>100_bases
AGGGTATGTGATTTTCATCACATACTTTTTTTTGTATGCACTATAGAATAGAGTATAAGAAATAATGGAGTTATTAAAAA
AAGAAAGGAGATGTTGGATC

Downstream 100 bases:

>100_bases
TTTTAAGAGGTGAAACATAATGGGTTTTAAGATTAGAAAAGAAAATTTTAATAGTGCTTTAAAAAATTTAAGAAAAGATT
TTAAAGTTTATGGACCTACT

Product: formate/nitrite transporter family protein

Products: Proton [Cytoplasm]; nitrite [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MYSEEINKISNVAENKRDLLRNNRVGYLVSSALAGIYVGIGTILIFTLGGNLEAVNSSYVKLIMGLSFGIALSLVIMAGS
ELFTGNNMVMAIGTLNKKTTWKDALSIWGNSFAGNLIGSMLLALIFVNAGLAKGSVGKFILKTAETKMTLSPMELFLRGL
LCNILVCLAVWCSLKMKEEAGKLIMIFWCLFAFISSGFEHSVANMTLFSIALFIPHGVGISVNGMAYNLIFVSLGNIIGG
ALFVGAAYYKISKK

Sequences:

>Translated_254_residues
MYSEEINKISNVAENKRDLLRNNRVGYLVSSALAGIYVGIGTILIFTLGGNLEAVNSSYVKLIMGLSFGIALSLVIMAGS
ELFTGNNMVMAIGTLNKKTTWKDALSIWGNSFAGNLIGSMLLALIFVNAGLAKGSVGKFILKTAETKMTLSPMELFLRGL
LCNILVCLAVWCSLKMKEEAGKLIMIFWCLFAFISSGFEHSVANMTLFSIALFIPHGVGISVNGMAYNLIFVSLGNIIGG
ALFVGAAYYKISKK
>Mature_254_residues
MYSEEINKISNVAENKRDLLRNNRVGYLVSSALAGIYVGIGTILIFTLGGNLEAVNSSYVKLIMGLSFGIALSLVIMAGS
ELFTGNNMVMAIGTLNKKTTWKDALSIWGNSFAGNLIGSMLLALIFVNAGLAKGSVGKFILKTAETKMTLSPMELFLRGL
LCNILVCLAVWCSLKMKEEAGKLIMIFWCLFAFISSGFEHSVANMTLFSIALFIPHGVGISVNGMAYNLIFVSLGNIIGG
ALFVGAAYYKISKK

Specific function: May act as a nitrite transporter [H]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI87082249, Length=255, Percent_Identity=43.921568627451, Blast_Score=199, Evalue=1e-52,
Organism=Escherichia coli, GI1787132, Length=238, Percent_Identity=30.672268907563, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1788837, Length=264, Percent_Identity=28.030303030303, Blast_Score=78, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6321779, Length=225, Percent_Identity=32, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 27325; Mature: 27325

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS01005 FORMATE_NITRITE_TP_1 ; PS01006 FORMATE_NITRITE_TP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSEEINKISNVAENKRDLLRNNRVGYLVSSALAGIYVGIGTILIFTLGGNLEAVNSSYV
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHH
KLIMGLSFGIALSLVIMAGSELFTGNNMVMAIGTLNKKTTWKDALSIWGNSFAGNLIGSM
HHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHH
LLALIFVNAGLAKGSVGKFILKTAETKMTLSPMELFLRGLLCNILVCLAVWCSLKMKEEA
HHHHHHHHCCCCCCCHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHCCHHHHHC
GKLIMIFWCLFAFISSGFEHSVANMTLFSIALFIPHGVGISVNGMAYNLIFVSLGNIIGG
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHH
ALFVGAAYYKISKK
HHHHHHHHHEECCC
>Mature Secondary Structure
MYSEEINKISNVAENKRDLLRNNRVGYLVSSALAGIYVGIGTILIFTLGGNLEAVNSSYV
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHH
KLIMGLSFGIALSLVIMAGSELFTGNNMVMAIGTLNKKTTWKDALSIWGNSFAGNLIGSM
HHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHH
LLALIFVNAGLAKGSVGKFILKTAETKMTLSPMELFLRGLLCNILVCLAVWCSLKMKEEA
HHHHHHHHCCCCCCCHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHCCHHHHHC
GKLIMIFWCLFAFISSGFEHSVANMTLFSIALFIPHGVGISVNGMAYNLIFVSLGNIIGG
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHH
ALFVGAAYYKISKK
HHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; nitrite [Periplasm] [C]

Specific reaction: Proton [Periplasm] + nitrite [Periplasm] = Proton [Cytoplasm] + nitrite [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1987123; 11677609 [H]