Click here to switch to the map view.

The map label for this gene is gpmI

Identifier: 153936169

GI number: 153936169

Start: 263579

End: 265108

Strand: Direct

Name: gpmI

Synonym: CLC_0285

Alternate gene names: 153936169

Gene position: 263579-265108 (Clockwise)

Preceding gene: 153935201

Following gene: 153936384

Centisome position: 7.01

GC content: 31.57

Gene sequence:

>1530_bases
ATGAGTAAAAAGCCAGTAGTTTTAATGATACTAGATGGATTTGGATTAACAAATAAGGTAGATGGCAATGCAGTATCAGC
AGCCAATAAGCCTAATTTAGATAATATATTAAAAAAATATCCTCATACTCAATTAGGTGCCAGTGGAATGGATGTAGGCC
TTCCAGAAGGTCAAATGGGTAATTCAGAAGTAGGACATTTAAATATAGGTGCAGGAAGAATAGTATATCAAGCCCTTACA
AAAATAACAAAATCTATTTCTGATGGAGATTTTTTTGAAAATGTAGCTTTAAATAAAGCTATAGAAAATGTAAAGAAAAA
TAATTCTACCCTACATCTTTTAGGTCTTTTATCACCAGGTGGAGTACATTCTCATATAGACCATTTAAAAGGTTTAATAA
AATTAGCAAAAGAAAAGGATATTAAAAAAGTTTATATTCATGCATTTTTAGATGGAAGAGATGTAGCCCCATCATCAGCT
AAAGAATATATAGAAGATATAGAAAACTATATGAATGAAATTGGTGTAGGTGAAATAGCTACAATATCAGGAAGATATTA
TGCTATGGACAGAGATAAAAGATGGGAAAGGGTACAGCTTTGTTATAATGCCATTGTACTAGGAAAAGGTGAAGAAGCTA
ATTCAGCAGTAGAAGGTTTAGAAAAATCTTATAGAGATAATAAAACTGATGAATTTGTTTTACCATCAGTAGTATTAAAA
GAAGGAAAACCTAAGGCAAAAATAGAAAATAAAGATTCAGTAGTATTCTTTAACTTTAGACCAGATAGAGCTAGAGAACT
TACAAGAGCTATAAATGATAAAGTATTTGATGGTTTTGAAAGAGAAACTTTAGATTTAACTTATGTTACTGTGACAGAAT
ATGATAGTACTTTAGAAAATGTAGAGGTAGCTTTTCCTCCAGAGCATTTAAATAATACTTTAGGAGAATATGTAAGCAAA
AATGGTAAAAAACAATTAAGAATAGCTGAAACAGAAAAATATGCTCATGTTACTTTCTTCTTTAATGGTGGAGTAGAAGA
GCCTAATGAAGGAGAAGATAGAGTTTTAATTCCATCACCAAAGGTAGCAACTTACGATATGCAACCAGAAATGAATGCAT
ATGAAGTTACAGATAAGCTTTTAGAAAGACTAGATGAAGATAAATACGATATGGTAATATTAAACTTTGCAAATCCAGAT
ATGGTAGGCCATACAGGAGTATTTGAAGCAGCAAAAAAAGCTATAGAAACTGTGGATGAATGTGTAGGTAAAATAGTTAA
TAAAGTTTTAGAAAAGGATGGAACAGCATTTATTACAGCTGATCATGGAAATTCAGAAGAAATGATAGACTATTCTACAG
GAAAGCCTATGACTGCCCATACAACAAACCCAGTACCATTTATGTATGTGTCTAAGAATAGTAAAGAGCTAAGAGAGGGT
GGCAAACTAGCAGACATAGCACCAACAATGTTACAACTCATGAACCTTCCTAAACCCTCTGAAATGACAGGGAATAGTCT
TATTAAATAA

Upstream 100 bases:

>100_bases
AATTATTAAAAGTGACAAGTGACAAGCTATAAGTTACAAATTGTTTTATATTAGCACTTCTCATTTGTATATTTTTATTT
AATGAGATTTGGAGGTAGAA

Downstream 100 bases:

>100_bases
TAGGGAAACTATATTTAAGATAAAATAATTTTTTTAAAAATAAGGAGGACCCAACATGAAAAATTATATTGAAATAGTAG
ATGTATACGCAAGACAAATC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MSKKPVVLMILDGFGLTNKVDGNAVSAANKPNLDNILKKYPHTQLGASGMDVGLPEGQMGNSEVGHLNIGAGRIVYQALT
KITKSISDGDFFENVALNKAIENVKKNNSTLHLLGLLSPGGVHSHIDHLKGLIKLAKEKDIKKVYIHAFLDGRDVAPSSA
KEYIEDIENYMNEIGVGEIATISGRYYAMDRDKRWERVQLCYNAIVLGKGEEANSAVEGLEKSYRDNKTDEFVLPSVVLK
EGKPKAKIENKDSVVFFNFRPDRARELTRAINDKVFDGFERETLDLTYVTVTEYDSTLENVEVAFPPEHLNNTLGEYVSK
NGKKQLRIAETEKYAHVTFFFNGGVEEPNEGEDRVLIPSPKVATYDMQPEMNAYEVTDKLLERLDEDKYDMVILNFANPD
MVGHTGVFEAAKKAIETVDECVGKIVNKVLEKDGTAFITADHGNSEEMIDYSTGKPMTAHTTNPVPFMYVSKNSKELREG
GKLADIAPTMLQLMNLPKPSEMTGNSLIK

Sequences:

>Translated_509_residues
MSKKPVVLMILDGFGLTNKVDGNAVSAANKPNLDNILKKYPHTQLGASGMDVGLPEGQMGNSEVGHLNIGAGRIVYQALT
KITKSISDGDFFENVALNKAIENVKKNNSTLHLLGLLSPGGVHSHIDHLKGLIKLAKEKDIKKVYIHAFLDGRDVAPSSA
KEYIEDIENYMNEIGVGEIATISGRYYAMDRDKRWERVQLCYNAIVLGKGEEANSAVEGLEKSYRDNKTDEFVLPSVVLK
EGKPKAKIENKDSVVFFNFRPDRARELTRAINDKVFDGFERETLDLTYVTVTEYDSTLENVEVAFPPEHLNNTLGEYVSK
NGKKQLRIAETEKYAHVTFFFNGGVEEPNEGEDRVLIPSPKVATYDMQPEMNAYEVTDKLLERLDEDKYDMVILNFANPD
MVGHTGVFEAAKKAIETVDECVGKIVNKVLEKDGTAFITADHGNSEEMIDYSTGKPMTAHTTNPVPFMYVSKNSKELREG
GKLADIAPTMLQLMNLPKPSEMTGNSLIK
>Mature_508_residues
SKKPVVLMILDGFGLTNKVDGNAVSAANKPNLDNILKKYPHTQLGASGMDVGLPEGQMGNSEVGHLNIGAGRIVYQALTK
ITKSISDGDFFENVALNKAIENVKKNNSTLHLLGLLSPGGVHSHIDHLKGLIKLAKEKDIKKVYIHAFLDGRDVAPSSAK
EYIEDIENYMNEIGVGEIATISGRYYAMDRDKRWERVQLCYNAIVLGKGEEANSAVEGLEKSYRDNKTDEFVLPSVVLKE
GKPKAKIENKDSVVFFNFRPDRARELTRAINDKVFDGFERETLDLTYVTVTEYDSTLENVEVAFPPEHLNNTLGEYVSKN
GKKQLRIAETEKYAHVTFFFNGGVEEPNEGEDRVLIPSPKVATYDMQPEMNAYEVTDKLLERLDEDKYDMVILNFANPDM
VGHTGVFEAAKKAIETVDECVGKIVNKVLEKDGTAFITADHGNSEEMIDYSTGKPMTAHTTNPVPFMYVSKNSKELREGG
KLADIAPTMLQLMNLPKPSEMTGNSLIK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=510, Percent_Identity=51.9607843137255, Blast_Score=551, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI32564249, Length=513, Percent_Identity=43.2748538011696, Blast_Score=428, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI17507741, Length=513, Percent_Identity=43.2748538011696, Blast_Score=428, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_CLOB1 (A7FQN9)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001382633.1
- ProteinModelPortal:   A7FQN9
- SMR:   A7FQN9
- STRING:   A7FQN9
- GeneID:   5396732
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_0270
- eggNOG:   COG0696
- HOGENOM:   HBG613255
- OMA:   DNKTDEF
- ProtClustDB:   PRK05434
- BioCyc:   CBOT441770:CLB_0270-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 56521; Mature: 56390

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: ACT_SITE 62-62

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKPVVLMILDGFGLTNKVDGNAVSAANKPNLDNILKKYPHTQLGASGMDVGLPEGQMG
CCCCCEEEEEECCCCCCCCCCCCEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCC
NSEVGHLNIGAGRIVYQALTKITKSISDGDFFENVALNKAIENVKKNNSTLHLLGLLSPG
CCCCCEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
GVHSHIDHLKGLIKLAKEKDIKKVYIHAFLDGRDVAPSSAKEYIEDIENYMNEIGVGEIA
CHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEE
TISGRYYAMDRDKRWERVQLCYNAIVLGKGEEANSAVEGLEKSYRDNKTDEFVLPSVVLK
EECCEEEEECCCCHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHCCCCCCCEECCHHHHH
EGKPKAKIENKDSVVFFNFRPDRARELTRAINDKVFDGFERETLDLTYVTVTEYDSTLEN
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCHHC
VEVAFPPEHLNNTLGEYVSKNGKKQLRIAETEKYAHVTFFFNGGVEEPNEGEDRVLIPSP
CEEEECHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEEECCCCCCCCCCCEEEECCC
KVATYDMQPEMNAYEVTDKLLERLDEDKYDMVILNFANPDMVGHTGVFEAAKKAIETVDE
CEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
CVGKIVNKVLEKDGTAFITADHGNSEEMIDYSTGKPMTAHTTNPVPFMYVSKNSKELREG
HHHHHHHHHHHCCCCEEEEECCCCCCCEEEECCCCCEEECCCCCCEEEEECCCHHHHHCC
GKLADIAPTMLQLMNLPKPSEMTGNSLIK
CCCHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKKPVVLMILDGFGLTNKVDGNAVSAANKPNLDNILKKYPHTQLGASGMDVGLPEGQMG
CCCCEEEEEECCCCCCCCCCCCEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCC
NSEVGHLNIGAGRIVYQALTKITKSISDGDFFENVALNKAIENVKKNNSTLHLLGLLSPG
CCCCCEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
GVHSHIDHLKGLIKLAKEKDIKKVYIHAFLDGRDVAPSSAKEYIEDIENYMNEIGVGEIA
CHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEE
TISGRYYAMDRDKRWERVQLCYNAIVLGKGEEANSAVEGLEKSYRDNKTDEFVLPSVVLK
EECCEEEEECCCCHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHCCCCCCCEECCHHHHH
EGKPKAKIENKDSVVFFNFRPDRARELTRAINDKVFDGFERETLDLTYVTVTEYDSTLEN
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCHHC
VEVAFPPEHLNNTLGEYVSKNGKKQLRIAETEKYAHVTFFFNGGVEEPNEGEDRVLIPSP
CEEEECHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEEECCCCCCCCCCCEEEECCC
KVATYDMQPEMNAYEVTDKLLERLDEDKYDMVILNFANPDMVGHTGVFEAAKKAIETVDE
CEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
CVGKIVNKVLEKDGTAFITADHGNSEEMIDYSTGKPMTAHTTNPVPFMYVSKNSKELREG
HHHHHHHHHHHCCCCEEEEECCCCCCCEEEECCCCCEEECCCCCCEEEEECCCHHHHHCC
GKLADIAPTMLQLMNLPKPSEMTGNSLIK
CCCHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA