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The map label for this gene is opuE [H]

Identifier: 153935933

GI number: 153935933

Start: 3702102

End: 3703475

Strand: Direct

Name: opuE [H]

Synonym: CLC_3563

Alternate gene names: 153935933

Gene position: 3702102-3703475 (Clockwise)

Preceding gene: 153934957

Following gene: 153935463

Centisome position: 98.45

GC content: 29.4

Gene sequence:

>1374_bases
TTGCTTATAGTAAGTATAATTTTAACATTAATTTTAACTGGAGTCGCTGGATATATTGGAAAACTAAAAGTAAAAACAGC
CAAGGACTTTATAAATGCAGACAATAAATTAGGTATATTAGGAGTAACCAGCATGCTTATGGGCTCTATAATAGGCGGTG
CTTCCACTGTAGGTACTGCACAAATGGCTTATAAACATGGGATATCTGCTATATGGTTTATATTAGGTTTGTGTATTGCT
AGTATTTTATTAGGACTCATATATTCAAACCAAGTTGGTAAGGACAGTATGACTACTCTACCTCAAATTATAGGAAACAC
TTATGGATTAAAAGCAAGAACTAGCTCTAGCTTACTATTATCTTTAGGTATGTTTATTCATATAAGTGGCCAAGTATTAG
CCTGCACTCCTCTTTTTACATCTATATTTAACATAGATGTAAAAATAACTTCTATAATAGTAATTTTTTTATTAGTTTTT
TATATAATTTTCGGAGGTTTTTGGGGAAGTACTATGGTAGGTGCTGTTAAAACCGTACTTTTATATGGTACAAGTATAAT
ATGTGGATTTATATTAATATTTTCACTAAATGGAACTGCAGAAATTTTTAATTATTTTCCTAAAAATCCTTGGTTCAATA
TATTTAGTGATGGTATTTTTCAAGATTTAGCCTTAGGATTTTCTACAGTACTTGGAATACTATCTACTCAGACTTACTTT
CAATCTATTATGGCTGGTAAAAACCCAAAAACTTCTAAAATAAGTTCTTTTTTAGTAGCCTTTTTAATATTTCCAGTAGG
TATTGTATGTACATCTATAGGAATGTACATGAAAATTCACTTTCCAAACATAAACCCTAATGAAGCTTTTCCTCTGTTTT
TAATTAATTACCTTCACCCAATTTTAGGTGGAGTATCTATAGCTACAGTGCTTATATCTTCCATAGCTACTGGAGCTGGA
TTAGCTTTGGGTATAGCTACCATGATGGTAAAAGATATTATACCAATTTTATCTAATAAAAAATTAGAGGATAAAAAAGA
AATTTTATATTTAAGAATATGTATTCTAATAATAGGTGTCTTAACCTTAATTATAGTTATAAATAACACCGATTCCATGA
TATTAGATTGGGGATTCTTATCTATGATATTTAGAGCTACGCCTATTTTTATACCGGCATTATGTGCACTATTTTTTAAA
AGCAAGATTAATAGCAAAGCAGGATTTTACTCTATATTAGCTGGTCCACTATCAAGTATTTTGTGGATAATCATTGGATT
TAGCCAAATAACCTCTATATATATAGGTATTACCATGAATATACTTGCTATGGCTACAGCAAGTAAGAAGTTTAATTATA
TGGAAAAAATATAA

Upstream 100 bases:

>100_bases
AATTAACTCATATTTAGTGTATTATTAGATTTGAAATAAAAACATATATATCTTTTATTGCTATAATAATATTATTAGAC
ATTAAAAAGGGGATGGGACA

Downstream 100 bases:

>100_bases
ATCTTCTTTTCTGCTGTATTAAAAAACCTCTTTTGATTAAAGATAATACTATATTAATTAAAGGAGGTTTAGTATGGCTA
AAAAAGGAATGAAAAGACCA

Product: sodium:solute symporter family protein

Products: NA

Alternate protein names: Sodium/proline symporter [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MLIVSIILTLILTGVAGYIGKLKVKTAKDFINADNKLGILGVTSMLMGSIIGGASTVGTAQMAYKHGISAIWFILGLCIA
SILLGLIYSNQVGKDSMTTLPQIIGNTYGLKARTSSSLLLSLGMFIHISGQVLACTPLFTSIFNIDVKITSIIVIFLLVF
YIIFGGFWGSTMVGAVKTVLLYGTSIICGFILIFSLNGTAEIFNYFPKNPWFNIFSDGIFQDLALGFSTVLGILSTQTYF
QSIMAGKNPKTSKISSFLVAFLIFPVGIVCTSIGMYMKIHFPNINPNEAFPLFLINYLHPILGGVSIATVLISSIATGAG
LALGIATMMVKDIIPILSNKKLEDKKEILYLRICILIIGVLTLIIVINNTDSMILDWGFLSMIFRATPIFIPALCALFFK
SKINSKAGFYSILAGPLSSILWIIIGFSQITSIYIGITMNILAMATASKKFNYMEKI

Sequences:

>Translated_457_residues
MLIVSIILTLILTGVAGYIGKLKVKTAKDFINADNKLGILGVTSMLMGSIIGGASTVGTAQMAYKHGISAIWFILGLCIA
SILLGLIYSNQVGKDSMTTLPQIIGNTYGLKARTSSSLLLSLGMFIHISGQVLACTPLFTSIFNIDVKITSIIVIFLLVF
YIIFGGFWGSTMVGAVKTVLLYGTSIICGFILIFSLNGTAEIFNYFPKNPWFNIFSDGIFQDLALGFSTVLGILSTQTYF
QSIMAGKNPKTSKISSFLVAFLIFPVGIVCTSIGMYMKIHFPNINPNEAFPLFLINYLHPILGGVSIATVLISSIATGAG
LALGIATMMVKDIIPILSNKKLEDKKEILYLRICILIIGVLTLIIVINNTDSMILDWGFLSMIFRATPIFIPALCALFFK
SKINSKAGFYSILAGPLSSILWIIIGFSQITSIYIGITMNILAMATASKKFNYMEKI
>Mature_457_residues
MLIVSIILTLILTGVAGYIGKLKVKTAKDFINADNKLGILGVTSMLMGSIIGGASTVGTAQMAYKHGISAIWFILGLCIA
SILLGLIYSNQVGKDSMTTLPQIIGNTYGLKARTSSSLLLSLGMFIHISGQVLACTPLFTSIFNIDVKITSIIVIFLLVF
YIIFGGFWGSTMVGAVKTVLLYGTSIICGFILIFSLNGTAEIFNYFPKNPWFNIFSDGIFQDLALGFSTVLGILSTQTYF
QSIMAGKNPKTSKISSFLVAFLIFPVGIVCTSIGMYMKIHFPNINPNEAFPLFLINYLHPILGGVSIATVLISSIATGAG
LALGIATMMVKDIIPILSNKKLEDKKEILYLRICILIIGVLTLIIVINNTDSMILDWGFLSMIFRATPIFIPALCALFFK
SKINSKAGFYSILAGPLSSILWIIIGFSQITSIYIGITMNILAMATASKKFNYMEKI

Specific function: Catalyzes the sodium-dependent uptake of extracellular proline [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011851
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 49515; Mature: 49515

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIVSIILTLILTGVAGYIGKLKVKTAKDFINADNKLGILGVTSMLMGSIIGGASTVGTA
CHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCHHHHHH
QMAYKHGISAIWFILGLCIASILLGLIYSNQVGKDSMTTLPQIIGNTYGLKARTSSSLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHH
SLGMFIHISGQVLACTPLFTSIFNIDVKITSIIVIFLLVFYIIFGGFWGSTMVGAVKTVL
HHHHHHEECCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGTSIICGFILIFSLNGTAEIFNYFPKNPWFNIFSDGIFQDLALGFSTVLGILSTQTYF
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSIMAGKNPKTSKISSFLVAFLIFPVGIVCTSIGMYMKIHFPNINPNEAFPLFLINYLHP
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHH
ILGGVSIATVLISSIATGAGLALGIATMMVKDIIPILSNKKLEDKKEILYLRICILIIGV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LTLIIVINNTDSMILDWGFLSMIFRATPIFIPALCALFFKSKINSKAGFYSILAGPLSSI
HHHHEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LWIIIGFSQITSIYIGITMNILAMATASKKFNYMEKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLIVSIILTLILTGVAGYIGKLKVKTAKDFINADNKLGILGVTSMLMGSIIGGASTVGTA
CHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCHHHHHH
QMAYKHGISAIWFILGLCIASILLGLIYSNQVGKDSMTTLPQIIGNTYGLKARTSSSLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHH
SLGMFIHISGQVLACTPLFTSIFNIDVKITSIIVIFLLVFYIIFGGFWGSTMVGAVKTVL
HHHHHHEECCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGTSIICGFILIFSLNGTAEIFNYFPKNPWFNIFSDGIFQDLALGFSTVLGILSTQTYF
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSIMAGKNPKTSKISSFLVAFLIFPVGIVCTSIGMYMKIHFPNINPNEAFPLFLINYLHP
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHH
ILGGVSIATVLISSIATGAGLALGIATMMVKDIIPILSNKKLEDKKEILYLRICILIIGV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LTLIIVINNTDSMILDWGFLSMIFRATPIFIPALCALFFKSKINSKAGFYSILAGPLSSI
HHHHEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LWIIIGFSQITSIYIGITMNILAMATASKKFNYMEKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969499; 9384377 [H]