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The map label for this gene is der [H]

Identifier: 153934957

GI number: 153934957

Start: 3700588

End: 3701787

Strand: Direct

Name: der [H]

Synonym: CLC_3562

Alternate gene names: 153934957

Gene position: 3700588-3701787 (Clockwise)

Preceding gene: 153936420

Following gene: 153935933

Centisome position: 98.41

GC content: 26.17

Gene sequence:

>1200_bases
ATGAATACTACACCTAATGCCAATAGAATTCATATAACTTTTATAGGTAAAACTAATTCTGGAAAGTCTTCTTTAATGAA
TGCAATAATAGGTCAAGATATATCTATTGTATCACCTATAGAAGGTACCACTACTGATCCTGTAAGTAAATCTATGGAAC
TTATACCTTTAGGTCCAGTTTTATTTACAGATACTGCTGGATTAGAAGATAACACTGAGCTTGGTAAAGTAAGAATTGAA
AAAACCTTAAATACTCTTTTAAAAACAGATTTTGCTATATATGTTATGTCTGCTAAAGATATTGATATAAACCTATATAA
GAAAACTATAAATAAATTTAAAGAGCAAAATATTTCTTATATAACAGTTATAAACAAAATGGATACTATAGAGAAAAATA
AAATAGATGACCTAAAAAAAATAATAGAAAGCCCCATATTTCTCTCAGCTAATAATATTAATAGTATCCTTAATTTAAAA
AATTTAATAATAGAAAATTTAAGTAAATCTAAAGAAGATGACACTATTATAGGTACTCTACTTCCCTACAATAGTAAGAT
AATTATGGTAGTACCTATAGATTCTGAAGCTCCAAAGGGTAGACTAATATTACCACAAGTGCAATTAATAAGAGATTGTT
TAGATCATGGTATAAAAAGCTATGTAGTTAGAGATACGGAATTAAAGTCTGCATTAGATGATATAAAAAATATAGATTTA
GTTGTAACAGATTCACAAGCCTTTAAAGAAGTAGATGAGATTGTTCCTAAAGACATAAGCCTAACAAGTTTTTCTATATT
ACTTGCTAATTATAAAGGTGATTTAAAAACTTTTGTAGAAGGAACTAAAGCTATAAATAACTTAAATGAAAATTCTAGAA
TACTTATATCAGAAAGTTGTACACATAATTATTCTCATGAAGATATAGGCAGAGTTAAAATACCTAACATGATTAATTCA
CATGTGGATAAAAAATTAAACTATGAATTTAAAATGGGTGGAGATTTTCCACAGGATGTGGATAAATACGATTTAATAAT
TCATTGTGGTGCTTGCATGGTAAATAAAAAATCTATGGATTCAAAACTTAAGCTATGCAAAGAAAAAAATATACCTATAA
CCAACTATGGTATACTAATCTCCTATTTAACAGGTATATTAGATAGAAGTATAGAACTATTTAATATAAAACTTAAATAA

Upstream 100 bases:

>100_bases
AGATAAATAAAATAAAAAGAGAAGATATTAAAAATATAGTTATTCAAAACATAGAAAAAATAAAAAATGGTGAAAGAGAT
TTATTTTTTTAGGAGGATTT

Downstream 100 bases:

>100_bases
AAAATTGTTACTTTAAAATGAATCTAACATAAAAAATACACTTAATAAACATATGAGTTTGTTTATTAAGTGTATTTTTC
ATATTTTCGGTGTTAAGATT

Product: GTP-binding protein

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MNTTPNANRIHITFIGKTNSGKSSLMNAIIGQDISIVSPIEGTTTDPVSKSMELIPLGPVLFTDTAGLEDNTELGKVRIE
KTLNTLLKTDFAIYVMSAKDIDINLYKKTINKFKEQNISYITVINKMDTIEKNKIDDLKKIIESPIFLSANNINSILNLK
NLIIENLSKSKEDDTIIGTLLPYNSKIIMVVPIDSEAPKGRLILPQVQLIRDCLDHGIKSYVVRDTELKSALDDIKNIDL
VVTDSQAFKEVDEIVPKDISLTSFSILLANYKGDLKTFVEGTKAINNLNENSRILISESCTHNYSHEDIGRVKIPNMINS
HVDKKLNYEFKMGGDFPQDVDKYDLIIHCGACMVNKKSMDSKLKLCKEKNIPITNYGILISYLTGILDRSIELFNIKLK

Sequences:

>Translated_399_residues
MNTTPNANRIHITFIGKTNSGKSSLMNAIIGQDISIVSPIEGTTTDPVSKSMELIPLGPVLFTDTAGLEDNTELGKVRIE
KTLNTLLKTDFAIYVMSAKDIDINLYKKTINKFKEQNISYITVINKMDTIEKNKIDDLKKIIESPIFLSANNINSILNLK
NLIIENLSKSKEDDTIIGTLLPYNSKIIMVVPIDSEAPKGRLILPQVQLIRDCLDHGIKSYVVRDTELKSALDDIKNIDL
VVTDSQAFKEVDEIVPKDISLTSFSILLANYKGDLKTFVEGTKAINNLNENSRILISESCTHNYSHEDIGRVKIPNMINS
HVDKKLNYEFKMGGDFPQDVDKYDLIIHCGACMVNKKSMDSKLKLCKEKNIPITNYGILISYLTGILDRSIELFNIKLK
>Mature_399_residues
MNTTPNANRIHITFIGKTNSGKSSLMNAIIGQDISIVSPIEGTTTDPVSKSMELIPLGPVLFTDTAGLEDNTELGKVRIE
KTLNTLLKTDFAIYVMSAKDIDINLYKKTINKFKEQNISYITVINKMDTIEKNKIDDLKKIIESPIFLSANNINSILNLK
NLIIENLSKSKEDDTIIGTLLPYNSKIIMVVPIDSEAPKGRLILPQVQLIRDCLDHGIKSYVVRDTELKSALDDIKNIDL
VVTDSQAFKEVDEIVPKDISLTSFSILLANYKGDLKTFVEGTKAINNLNENSRILISESCTHNYSHEDIGRVKIPNMINS
HVDKKLNYEFKMGGDFPQDVDKYDLIIHCGACMVNKKSMDSKLKLCKEKNIPITNYGILISYLTGILDRSIELFNIKLK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasmic; may also be associated with the inner membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 44716; Mature: 44716

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTPNANRIHITFIGKTNSGKSSLMNAIIGQDISIVSPIEGTTTDPVSKSMELIPLGPV
CCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCEEECCCCCCCCCCHHCCCEEEECCCE
LFTDTAGLEDNTELGKVRIEKTLNTLLKTDFAIYVMSAKDIDINLYKKTINKFKEQNISY
EEECCCCCCCCCCHHHEEHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEE
ITVINKMDTIEKNKIDDLKKIIESPIFLSANNINSILNLKNLIIENLSKSKEDDTIIGTL
EEEECCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
LPYNSKIIMVVPIDSEAPKGRLILPQVQLIRDCLDHGIKSYVVRDTELKSALDDIKNIDL
ECCCCEEEEEEECCCCCCCCCEECHHHHHHHHHHHCCHHHHEECCHHHHHHHHHHCCCEE
VVTDSQAFKEVDEIVPKDISLTSFSILLANYKGDLKTFVEGTKAINNLNENSRILISESC
EEECHHHHHHHHHHCCCCCCHHEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEECCC
THNYSHEDIGRVKIPNMINSHVDKKLNYEFKMGGDFPQDVDKYDLIIHCGACMVNKKSMD
CCCCCCCCCCCEECCHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEEEECCCEECCHHHH
SKLKLCKEKNIPITNYGILISYLTGILDRSIELFNIKLK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEC
>Mature Secondary Structure
MNTTPNANRIHITFIGKTNSGKSSLMNAIIGQDISIVSPIEGTTTDPVSKSMELIPLGPV
CCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCEEECCCCCCCCCCHHCCCEEEECCCE
LFTDTAGLEDNTELGKVRIEKTLNTLLKTDFAIYVMSAKDIDINLYKKTINKFKEQNISY
EEECCCCCCCCCCHHHEEHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEE
ITVINKMDTIEKNKIDDLKKIIESPIFLSANNINSILNLKNLIIENLSKSKEDDTIIGTL
EEEECCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
LPYNSKIIMVVPIDSEAPKGRLILPQVQLIRDCLDHGIKSYVVRDTELKSALDDIKNIDL
ECCCCEEEEEEECCCCCCCCCEECHHHHHHHHHHHCCHHHHEECCHHHHHHHHHHCCCEE
VVTDSQAFKEVDEIVPKDISLTSFSILLANYKGDLKTFVEGTKAINNLNENSRILISESC
EEECHHHHHHHHHHCCCCCCHHEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEECCC
THNYSHEDIGRVKIPNMINSHVDKKLNYEFKMGGDFPQDVDKYDLIIHCGACMVNKKSMD
CCCCCCCCCCCEECCHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEEEECCCEECCHHHH
SKLKLCKEKNIPITNYGILISYLTGILDRSIELFNIKLK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA