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The map label for this gene is dnaC [H]

Identifier: 153002957

GI number: 153002957

Start: 95034

End: 96458

Strand: Reverse

Name: dnaC [H]

Synonym: Anae109_0078

Alternate gene names: 153002957

Gene position: 96458-95034 (Counterclockwise)

Preceding gene: 153002965

Following gene: 153002953

Centisome position: 1.83

GC content: 70.53

Gene sequence:

>1425_bases
ATGGCCGAGCACGACCCCGTCCGACGCGTCTCCGAGGCGCCCGTCGCACCCCTGCGCAGCGCCCGCGACCTGCCCCACAG
CCTCGAGGCCGAGCAGGCGGTCATCGGCGCGATCCTCGTCGAGGAGACCGCCTTCGACCAGGTCGCCGCGCTCATCAAGT
CGGGCGACTTCTACCTGCTCGCGCACCAGCACGTGTACGCGGTGTGCGAGGAGCTCGCGCGCGAGTCGAAGACGCTCGAC
CCCATCCTCGTGCAGCAGCGGCTCGACGCGAAGGGGCTCCTCGGCAGCGCCGTCCCCCGCGAGCTGCCGCTCTCGCTCGC
GCGCGCCATCGGCACGACCGCCAACGTGCAGCACTACGGGCGCACGGTGCAGGAGCTCGCCCGGCTGCGGCAGATGATGC
TCACCGCCCAGCGGGTGGTGGAGCGCGGCTACGAGGCGGGGGCGAGCGTCCAGCAGTTCCTCGACTCCGCCCAGCAGGAC
GTCTTCGGGGCGGCGCAGGGGACCGGCACCGAGACGCTGAAGAAGATCGCCGAGCCCGTGATGCGGGCGATCGAGAACCT
GGAGGCCGTCCAGAAGCGCGTCCAGGCCGGCCTCTCGCCCATCACCGGCGTGCCCACCGGCATCCAGTCGCTCGACAAGA
ACACCCTCGGGTTCCAGCCCGGCACGCTCACCGTGCTCGCCGCCCGCCCCTCGGTGGGCAAGACCGCCTTCGCGCTCAAC
ATCGCGACGCACGCGGCCACCCGGGCCGGCAAGAAGGTCGCGTTCTTCTCGCTCGAGATGCCCTCCGACCAGCTCGCGCT
CCGCATGCTGGCCTCGGAGGCCCGCCTCGACTGGCGGCGGCTCTCGGCGGGACAGCTCTCCGCCTACGACTGGCAGAAGA
TCGCCACGCACGCGGACAAGCTCGGCGCCGCCTCCATCTGGCTCGACGACAACTTCGTGCTGACCCCGGTCGAGCTGCGC
TCCAAGTGCCGCAAGCTGAAGCGCGAGAACGGCGGCCTCGACCTCGTGATGATCGACTACCTCCAGCTCATGCACGCCCC
GTCGGACCGCGCGAGCCAGTCGCGCGAGCAGGAGATCGCCACCATCAGCCGCTCGCTCAAGTCGCTCGCCAAGGAGCTCG
AGTGCCCCATCGTGGCGCTCTCGCAGCTCAACCGCGGCGTGGAGAAGCGCAAGGGGGAGCCGCCCATGCTCTCCGACCTG
CGCGAGTCGGGCGCCATCGAGCAGGACGCGGACATCGTCATGTTCCTGCACCGGAACGACGAGGACAACAAGGACGTCCA
GTCCGGCACCGCGAGCGGCGACACGCTCGAGGTCCAGCTCGTCGTGGCGAAGCAGCGCCAGGGTCCCACCGGCACGATCC
CGCTCGTCTTCTTCAAGACCACGACCTACTTCGCGGAGATGGAGCGGCGGCGCGACGGACAGTGA

Upstream 100 bases:

>100_bases
ACCCTCCCTCCACAGCGTTTTCCCCCGGTATTTCCGACGTTTTCCACCGCCTGTCCACGGTGATCCCGTCGGACCTCGCT
GGTAGGCTGCGCCGGTTCCC

Downstream 100 bases:

>100_bases
AGCTGCGCGGAGCTTCGCTCGGCGGGCCCCCGGTCTAGATCATCCGGTCGAGGTAGCGCTCCACGAGCCGCTTCGCGCCG
CGCACCGCCTCCTCGAGCGA

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MAEHDPVRRVSEAPVAPLRSARDLPHSLEAEQAVIGAILVEETAFDQVAALIKSGDFYLLAHQHVYAVCEELARESKTLD
PILVQQRLDAKGLLGSAVPRELPLSLARAIGTTANVQHYGRTVQELARLRQMMLTAQRVVERGYEAGASVQQFLDSAQQD
VFGAAQGTGTETLKKIAEPVMRAIENLEAVQKRVQAGLSPITGVPTGIQSLDKNTLGFQPGTLTVLAARPSVGKTAFALN
IATHAATRAGKKVAFFSLEMPSDQLALRMLASEARLDWRRLSAGQLSAYDWQKIATHADKLGAASIWLDDNFVLTPVELR
SKCRKLKRENGGLDLVMIDYLQLMHAPSDRASQSREQEIATISRSLKSLAKELECPIVALSQLNRGVEKRKGEPPMLSDL
RESGAIEQDADIVMFLHRNDEDNKDVQSGTASGDTLEVQLVVAKQRQGPTGTIPLVFFKTTTYFAEMERRRDGQ

Sequences:

>Translated_474_residues
MAEHDPVRRVSEAPVAPLRSARDLPHSLEAEQAVIGAILVEETAFDQVAALIKSGDFYLLAHQHVYAVCEELARESKTLD
PILVQQRLDAKGLLGSAVPRELPLSLARAIGTTANVQHYGRTVQELARLRQMMLTAQRVVERGYEAGASVQQFLDSAQQD
VFGAAQGTGTETLKKIAEPVMRAIENLEAVQKRVQAGLSPITGVPTGIQSLDKNTLGFQPGTLTVLAARPSVGKTAFALN
IATHAATRAGKKVAFFSLEMPSDQLALRMLASEARLDWRRLSAGQLSAYDWQKIATHADKLGAASIWLDDNFVLTPVELR
SKCRKLKRENGGLDLVMIDYLQLMHAPSDRASQSREQEIATISRSLKSLAKELECPIVALSQLNRGVEKRKGEPPMLSDL
RESGAIEQDADIVMFLHRNDEDNKDVQSGTASGDTLEVQLVVAKQRQGPTGTIPLVFFKTTTYFAEMERRRDGQ
>Mature_473_residues
AEHDPVRRVSEAPVAPLRSARDLPHSLEAEQAVIGAILVEETAFDQVAALIKSGDFYLLAHQHVYAVCEELARESKTLDP
ILVQQRLDAKGLLGSAVPRELPLSLARAIGTTANVQHYGRTVQELARLRQMMLTAQRVVERGYEAGASVQQFLDSAQQDV
FGAAQGTGTETLKKIAEPVMRAIENLEAVQKRVQAGLSPITGVPTGIQSLDKNTLGFQPGTLTVLAARPSVGKTAFALNI
ATHAATRAGKKVAFFSLEMPSDQLALRMLASEARLDWRRLSAGQLSAYDWQKIATHADKLGAASIWLDDNFVLTPVELRS
KCRKLKRENGGLDLVMIDYLQLMHAPSDRASQSREQEIATISRSLKSLAKELECPIVALSQLNRGVEKRKGEPPMLSDLR
ESGAIEQDADIVMFLHRNDEDNKDVQSGTASGDTLEVQLVVAKQRQGPTGTIPLVFFKTTTYFAEMERRRDGQ

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=446, Percent_Identity=40.3587443946188, Blast_Score=318, Evalue=7e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 51950; Mature: 51819

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEHDPVRRVSEAPVAPLRSARDLPHSLEAEQAVIGAILVEETAFDQVAALIKSGDFYLL
CCCCCHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
AHQHVYAVCEELARESKTLDPILVQQRLDAKGLLGSAVPRELPLSLARAIGTTANVQHYG
EHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHCCCCHHHHHH
RTVQELARLRQMMLTAQRVVERGYEAGASVQQFLDSAQQDVFGAAQGTGTETLKKIAEPV
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
MRAIENLEAVQKRVQAGLSPITGVPTGIQSLDKNTLGFQPGTLTVLAARPSVGKTAFALN
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEEE
IATHAATRAGKKVAFFSLEMPSDQLALRMLASEARLDWRRLSAGQLSAYDWQKIATHADK
HHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LGAASIWLDDNFVLTPVELRSKCRKLKRENGGLDLVMIDYLQLMHAPSDRASQSREQEIA
CCCEEEEECCCEEECCHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHH
TISRSLKSLAKELECPIVALSQLNRGVEKRKGEPPMLSDLRESGAIEQDADIVMFLHRND
HHHHHHHHHHHHHCCHHHHHHHHHCCHHHCCCCCCHHHHHHHCCCCCCCCCEEEEEECCC
EDNKDVQSGTASGDTLEVQLVVAKQRQGPTGTIPLVFFKTTTYFAEMERRRDGQ
CCCCHHHCCCCCCCEEEEEEEEEECCCCCCCCEEEEEEEHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AEHDPVRRVSEAPVAPLRSARDLPHSLEAEQAVIGAILVEETAFDQVAALIKSGDFYLL
CCCCHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
AHQHVYAVCEELARESKTLDPILVQQRLDAKGLLGSAVPRELPLSLARAIGTTANVQHYG
EHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHCCCCHHHHHH
RTVQELARLRQMMLTAQRVVERGYEAGASVQQFLDSAQQDVFGAAQGTGTETLKKIAEPV
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
MRAIENLEAVQKRVQAGLSPITGVPTGIQSLDKNTLGFQPGTLTVLAARPSVGKTAFALN
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEEE
IATHAATRAGKKVAFFSLEMPSDQLALRMLASEARLDWRRLSAGQLSAYDWQKIATHADK
HHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LGAASIWLDDNFVLTPVELRSKCRKLKRENGGLDLVMIDYLQLMHAPSDRASQSREQEIA
CCCEEEEECCCEEECCHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHH
TISRSLKSLAKELECPIVALSQLNRGVEKRKGEPPMLSDLRESGAIEQDADIVMFLHRND
HHHHHHHHHHHHHCCHHHHHHHHHCCHHHCCCCCCHHHHHHHCCCCCCCCCEEEEEECCC
EDNKDVQSGTASGDTLEVQLVVAKQRQGPTGTIPLVFFKTTTYFAEMERRRDGQ
CCCCHHHCCCCCCCEEEEEEEEEECCCCCCCCEEEEEEEHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]