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The map label for this gene is zraR [H]

Identifier: 153002965

GI number: 153002965

Start: 102967

End: 104379

Strand: Reverse

Name: zraR [H]

Synonym: Anae109_0086

Alternate gene names: 153002965

Gene position: 104379-102967 (Counterclockwise)

Preceding gene: 153002966

Following gene: 153002957

Centisome position: 1.98

GC content: 75.02

Gene sequence:

>1413_bases
ATGATCCCGTCCCTGCCCTATCTCGGCCTCGGCAGCGCTGAGTCGCTGCAGCAGGTCGCGGACGCATTCCCCGACGGCGT
CTTCACGACCGACCGGGACGGCGTGATCACCTACTGGAACCCCGCCGCCGGGGCGATCACCGGCTACTCCGCCGCGGAGG
CGATCGGCCGCACCTGCGCGCTCCTCGCCGGGGACATGGGGCGCGGCTGCATGTGCGGAGGCGGGCCGGTGCGCTGCGGG
ATCTCCGACCGCGGGAAGAGCTCCAAGTGCTGCAGCATCCGCACGAAGGACGGCCGGGAGCGGCTCATCGTGAAGAACGC
GGTGGCCTTCCACGGGCCGGACGGGACCGTCGCCGGCGCGCTCGAGAGCTTCACCGACGTCACGGACCTGAGCGTCGGCG
CCATCCCGTGGGAGAGCGCGTGCGCGCTCCCGGCTCCGTCCGCCGGCGTCGCCGCCGCGGCGGAGGCCGCGCCGCCGGAG
AGCGAGTGCGCAGGGCTCCTCGGCTGCCACCCGGTCATGCGCGAGCTGTACCGGATGATCGCCCTCGTCGCCCGCTCCGA
CGCGACGGTCATGATCCTGGGCGAGAGCGGCGTGGGAAAGGAGCGCGTGGCCGAGGCGATCCACCGGCAGAGCCGGCGCG
CGGCGGGGCCGCTCGTGCGGGTGTCGTGCTCCGCCCTCAACGAGAACCTCCTCGAGAGCGAGCTCTTCGGCCACGTGAAG
GGGGCGTTCACCGGGGCGCTGCGCGACCGGCGCGGCCGGTTCCAGGAGGCGCACGGCGGGACCCTCCTGCTCGACGAGAT
CGGCGACATCTCACCGGCGGTCCAGGTGAAGCTCCTGCGCGTCATCGAGCAGCGCGTGGTCGAGCGGGTGGGCGACTCGC
AACCGCTCCCGGTCGACGTGCGGCTCCTCTGCGCCACGCACCGGGACCTGAAGCAGCTCGTGACCGACGGCCGCTTCCGC
GCCGACCTGTACTTCCGCCTGGCGGTGTTCCCGCTCCGCGTGCCGCCGCTGCGCGAGCGCGCCGAGGACGTGGCGCTCCT
CTCGGAGGGCTTCCTCGCGCGGCTCGGCGCGCCGCCGCCCTCGCCGGAAGCGTCGCGGCTCCTCGCCGCCTACGCGTGGC
CGGGGAACGTGCGCGAGCTGCAGAACGTGCTCGAGTACGCGGCGCTGCAGGCGGGCGGCGCGCCCATCTCGCCCGCCCAC
CTCCCCGCCGAGATCCGCGGCGCCGCGCCGCCCACGCCGGAGCGCGCCGCGCCCGATCGCTCGGCGATCGTCGAGGCGCT
CATCCGGACCGGCTGGAACCGCGCGCGCGCCGCCGACGTGCTCGGCATCTCGCGCGTGACGCTGTGGAAGCGGATGAAGC
GGCTCGGCGTGGTGGGCCCCGGCCCGATGGCGTCCGGGCGGGAGCCGCTCTGA

Upstream 100 bases:

>100_bases
TTTCAGGGGGTTCAGACCCGATAGGGCTCCGGTCTGATAAGGTCTGCTCGTTCACGCAGACGTTTCCGTGGACCCCGACG
GAACCCCCCGAGCCCGACGC

Downstream 100 bases:

>100_bases
TTCAGCGCGCGGAGCGGCGGTTCTTGTCCACGATCGCCCAGATGAGCACGAGGAACGCCACGAGCCGCAGCACGTAGGCG
TTGTGCCGCGTCTCGTCGCC

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MIPSLPYLGLGSAESLQQVADAFPDGVFTTDRDGVITYWNPAAGAITGYSAAEAIGRTCALLAGDMGRGCMCGGGPVRCG
ISDRGKSSKCCSIRTKDGRERLIVKNAVAFHGPDGTVAGALESFTDVTDLSVGAIPWESACALPAPSAGVAAAAEAAPPE
SECAGLLGCHPVMRELYRMIALVARSDATVMILGESGVGKERVAEAIHRQSRRAAGPLVRVSCSALNENLLESELFGHVK
GAFTGALRDRRGRFQEAHGGTLLLDEIGDISPAVQVKLLRVIEQRVVERVGDSQPLPVDVRLLCATHRDLKQLVTDGRFR
ADLYFRLAVFPLRVPPLRERAEDVALLSEGFLARLGAPPPSPEASRLLAAYAWPGNVRELQNVLEYAALQAGGAPISPAH
LPAEIRGAAPPTPERAAPDRSAIVEALIRTGWNRARAADVLGISRVTLWKRMKRLGVVGPGPMASGREPL

Sequences:

>Translated_470_residues
MIPSLPYLGLGSAESLQQVADAFPDGVFTTDRDGVITYWNPAAGAITGYSAAEAIGRTCALLAGDMGRGCMCGGGPVRCG
ISDRGKSSKCCSIRTKDGRERLIVKNAVAFHGPDGTVAGALESFTDVTDLSVGAIPWESACALPAPSAGVAAAAEAAPPE
SECAGLLGCHPVMRELYRMIALVARSDATVMILGESGVGKERVAEAIHRQSRRAAGPLVRVSCSALNENLLESELFGHVK
GAFTGALRDRRGRFQEAHGGTLLLDEIGDISPAVQVKLLRVIEQRVVERVGDSQPLPVDVRLLCATHRDLKQLVTDGRFR
ADLYFRLAVFPLRVPPLRERAEDVALLSEGFLARLGAPPPSPEASRLLAAYAWPGNVRELQNVLEYAALQAGGAPISPAH
LPAEIRGAAPPTPERAAPDRSAIVEALIRTGWNRARAADVLGISRVTLWKRMKRLGVVGPGPMASGREPL
>Mature_470_residues
MIPSLPYLGLGSAESLQQVADAFPDGVFTTDRDGVITYWNPAAGAITGYSAAEAIGRTCALLAGDMGRGCMCGGGPVRCG
ISDRGKSSKCCSIRTKDGRERLIVKNAVAFHGPDGTVAGALESFTDVTDLSVGAIPWESACALPAPSAGVAAAAEAAPPE
SECAGLLGCHPVMRELYRMIALVARSDATVMILGESGVGKERVAEAIHRQSRRAAGPLVRVSCSALNENLLESELFGHVK
GAFTGALRDRRGRFQEAHGGTLLLDEIGDISPAVQVKLLRVIEQRVVERVGDSQPLPVDVRLLCATHRDLKQLVTDGRFR
ADLYFRLAVFPLRVPPLRERAEDVALLSEGFLARLGAPPPSPEASRLLAAYAWPGNVRELQNVLEYAALQAGGAPISPAH
LPAEIRGAAPPTPERAAPDRSAIVEALIRTGWNRARAADVLGISRVTLWKRMKRLGVVGPGPMASGREPL

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=304, Percent_Identity=51.6447368421053, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI1788550, Length=359, Percent_Identity=40.3899721448468, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI87082117, Length=312, Percent_Identity=46.474358974359, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1789087, Length=325, Percent_Identity=43.3846153846154, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI87082152, Length=329, Percent_Identity=45.2887537993921, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1789233, Length=371, Percent_Identity=37.7358490566038, Blast_Score=231, Evalue=9e-62,
Organism=Escherichia coli, GI1786524, Length=310, Percent_Identity=43.2258064516129, Blast_Score=228, Evalue=8e-61,
Organism=Escherichia coli, GI1790299, Length=332, Percent_Identity=39.4578313253012, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1788905, Length=295, Percent_Identity=42.0338983050847, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI87081872, Length=306, Percent_Identity=39.8692810457516, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1787583, Length=318, Percent_Identity=33.9622641509434, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI87081858, Length=302, Percent_Identity=33.7748344370861, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1789828, Length=232, Percent_Identity=36.2068965517241, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49730; Mature: 49730

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPSLPYLGLGSAESLQQVADAFPDGVFTTDRDGVITYWNPAAGAITGYSAAEAIGRTCA
CCCCCCCCCCCCHHHHHHHHHHCCCCCEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
LLAGDMGRGCMCGGGPVRCGISDRGKSSKCCSIRTKDGRERLIVKNAVAFHGPDGTVAGA
HHHCCCCCCEECCCCCEEECCCCCCCCCCEEEEECCCCCCEEEEEEEEEEECCCCHHHHH
LESFTDVTDLSVGAIPWESACALPAPSAGVAAAAEAAPPESECAGLLGCHPVMRELYRMI
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHCCHHHHHHHHHHH
ALVARSDATVMILGESGVGKERVAEAIHRQSRRAAGPLVRVSCSALNENLLESELFGHVK
HHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHH
GAFTGALRDRRGRFQEAHGGTLLLDEIGDISPAVQVKLLRVIEQRVVERVGDSQPLPVDV
HHHHHHHHHHHCCHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
RLLCATHRDLKQLVTDGRFRADLYFRLAVFPLRVPPLRERAEDVALLSEGFLARLGAPPP
HHHHHHHHHHHHHHHCCCEEHHEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
SPEASRLLAAYAWPGNVRELQNVLEYAALQAGGAPISPAHLPAEIRGAAPPTPERAAPDR
CCHHHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCH
SAIVEALIRTGWNRARAADVLGISRVTLWKRMKRLGVVGPGPMASGREPL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIPSLPYLGLGSAESLQQVADAFPDGVFTTDRDGVITYWNPAAGAITGYSAAEAIGRTCA
CCCCCCCCCCCCHHHHHHHHHHCCCCCEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
LLAGDMGRGCMCGGGPVRCGISDRGKSSKCCSIRTKDGRERLIVKNAVAFHGPDGTVAGA
HHHCCCCCCEECCCCCEEECCCCCCCCCCEEEEECCCCCCEEEEEEEEEEECCCCHHHHH
LESFTDVTDLSVGAIPWESACALPAPSAGVAAAAEAAPPESECAGLLGCHPVMRELYRMI
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHCCHHHHHHHHHHH
ALVARSDATVMILGESGVGKERVAEAIHRQSRRAAGPLVRVSCSALNENLLESELFGHVK
HHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHH
GAFTGALRDRRGRFQEAHGGTLLLDEIGDISPAVQVKLLRVIEQRVVERVGDSQPLPVDV
HHHHHHHHHHHCCHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
RLLCATHRDLKQLVTDGRFRADLYFRLAVFPLRVPPLRERAEDVALLSEGFLARLGAPPP
HHHHHHHHHHHHHHHCCCEEHHEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
SPEASRLLAAYAWPGNVRELQNVLEYAALQAGGAPISPAHLPAEIRGAAPPTPERAAPDR
CCHHHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCH
SAIVEALIRTGWNRARAADVLGISRVTLWKRMKRLGVVGPGPMASGREPL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]