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The map label for this gene is yycF [H]

Identifier: 152977665

GI number: 152977665

Start: 4064937

End: 4065644

Strand: Reverse

Name: yycF [H]

Synonym: Bcer98_4006

Alternate gene names: 152977665

Gene position: 4065644-4064937 (Counterclockwise)

Preceding gene: 152977666

Following gene: 152977664

Centisome position: 99.48

GC content: 37.57

Gene sequence:

>708_bases
ATGATGGGAAAAAAAATCTTAGTAGTTGATGATGAAAAGCCAATCGCAGATATTTTGAAGTTTAATCTAGAAAAAGAGGG
CTTTGAAATTGTAATGGCCCATGATGGGGATGAAGCAATCGAAAAGGCTAATGAAGAACAACCAGATATGGTTTTATTAG
ATATTATGTTACCAGGAAAAGATGGACTAGAGGTTTGTCGTGAAATCCGTAAAAGTTCTGAAATGCCAATTATTATGTTA
ACAGCAAAGGACTCTGAAATCGATAAAGTATTAGGACTAGAACTTGGAGCAGATGATTATGTTACAAAACCATTTAGTAC
GAGAGAACTGCTAGCTCGTGTAAAAGCGAACTTACGCCGTCATCAACAGGGCGGGGCAGCAGAAAAAGAGGAAAATACAG
AAATGGTCATTGGACCAATTGTTATTAATCCAAATGCGTATAGTGTAACGAAGCGAGAAGAGAGTATTGAACTTACGCAT
CGTGAATTTGAGTTACTACATTATTTAGCGAAGCATTTAGGACAAGTTATGACACGTGAGCATCTATTACAAACTGTATG
GGGTTATGATTATTTTGGGGATGTACGTACAGTAGACGTAACAGTACGTCGTTTACGTGAAAAGATTGAAGATAATCCAA
GTCATCCAACTCTAATTGTTACGAGACGTGGAGTAGGATATTACTTGCGTGACCCAGAGCAGGAATAA

Upstream 100 bases:

>100_bases
AATAGAGGAGAAAATACTTAAATGAAGGGTGAACTTTAAGCAGGAACTGCCTATATGTTTAAGGATTATTGACCATATTT
TTATGAGGAGGAAATACACG

Downstream 100 bases:

>100_bases
AACATGAAGAAAGTTGGTTTTTTTCAATCTATTCATTTTAAGTTTGTGCTCATCTATATGCTATTAATATTAATAGCAAT
GCAGGTTATCGGTGTATATT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MMGKKILVVDDEKPIADILKFNLEKEGFEIVMAHDGDEAIEKANEEQPDMVLLDIMLPGKDGLEVCREIRKSSEMPIIML
TAKDSEIDKVLGLELGADDYVTKPFSTRELLARVKANLRRHQQGGAAEKEENTEMVIGPIVINPNAYSVTKREESIELTH
REFELLHYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPTLIVTRRGVGYYLRDPEQE

Sequences:

>Translated_235_residues
MMGKKILVVDDEKPIADILKFNLEKEGFEIVMAHDGDEAIEKANEEQPDMVLLDIMLPGKDGLEVCREIRKSSEMPIIML
TAKDSEIDKVLGLELGADDYVTKPFSTRELLARVKANLRRHQQGGAAEKEENTEMVIGPIVINPNAYSVTKREESIELTH
REFELLHYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPTLIVTRRGVGYYLRDPEQE
>Mature_235_residues
MMGKKILVVDDEKPIADILKFNLEKEGFEIVMAHDGDEAIEKANEEQPDMVLLDIMLPGKDGLEVCREIRKSSEMPIIML
TAKDSEIDKVLGLELGADDYVTKPFSTRELLARVKANLRRHQQGGAAEKEENTEMVIGPIVINPNAYSVTKREESIELTH
REFELLHYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPTLIVTRRGVGYYLRDPEQE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=43.6681222707424, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=41.6666666666667, Blast_Score=170, Evalue=6e-44,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=39.3805309734513, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=38.5650224215247, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=39.2857142857143, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=39.6551724137931, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1790860, Length=236, Percent_Identity=37.2881355932203, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=38.5964912280702, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=34.0807174887892, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=36.0869565217391, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=35.0649350649351, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=33.1858407079646, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=33.7777777777778, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790552, Length=234, Percent_Identity=32.9059829059829, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=37.037037037037, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790299, Length=119, Percent_Identity=32.7731092436975, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787487, Length=105, Percent_Identity=31.4285714285714, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26928; Mature: 26928

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGKKILVVDDEKPIADILKFNLEKEGFEIVMAHDGDEAIEKANEEQPDMVLLDIMLPGK
CCCCEEEEEECCCCHHHHHHHCCCCCCEEEEEEECCHHHHHHCCCCCCCEEEEEEEECCC
DGLEVCREIRKSSEMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELLARVKANLRR
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHCEECCCCCCCCCCCHHHHHHHHHHHHHH
HQQGGAAEKEENTEMVIGPIVINPNAYSVTKREESIELTHREFELLHYLAKHLGQVMTRE
HHCCCCCCCCCCCCEEEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPTLIVTRRGVGYYLRDPEQE
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCCC
>Mature Secondary Structure
MMGKKILVVDDEKPIADILKFNLEKEGFEIVMAHDGDEAIEKANEEQPDMVLLDIMLPGK
CCCCEEEEEECCCCHHHHHHHCCCCCCEEEEEEECCHHHHHHCCCCCCCEEEEEEEECCC
DGLEVCREIRKSSEMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELLARVKANLRR
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHCEECCCCCCCCCCCHHHHHHHHHHHHHH
HQQGGAAEKEENTEMVIGPIVINPNAYSVTKREESIELTHREFELLHYLAKHLGQVMTRE
HHCCCCCCCCCCCCEEEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPTLIVTRRGVGYYLRDPEQE
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]