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The map label for this gene is lytS [H]

Identifier: 152977621

GI number: 152977621

Start: 4018001

End: 4019776

Strand: Reverse

Name: lytS [H]

Synonym: Bcer98_3959

Alternate gene names: 152977621

Gene position: 4019776-4018001 (Counterclockwise)

Preceding gene: 152977623

Following gene: 152977620

Centisome position: 98.35

GC content: 36.32

Gene sequence:

>1776_bases
ATGTTAGATTTAGTACTCATGATGATTGAGCGCGTTGGATTAATTGTTATATTAGGTTTTTTACTTTCGCATATTCGAAT
TTTTCGACATCTCCTTCATAAACAAGATGGATATAAGGATAAGCTTATGCTAATTTGTATTTTTTCATTATTTACAATTG
TAAGCAATTACACAGGAATTGAAATTGCAGGAAATACAATTATGAATGAAAATTGGTTACAAGGCGTTTCCTCGTCAAGT
ACGATTGCAAATACGCGTATTATGGGTGTCGGAATTAGCGGTTTACTAGGGGGACCCATTGTCGGAATTGGTGTTGGGTT
TATTTCTGGTATTCATCGCTATATGCTAGGGGGGACGACAGCTTTTAGCTGTGCTATTTCATCTATTTTAGCAGGGATCA
TTACAGGATATATTGGCCGAATTTTTCAAAAGCATAATCGTACAGTTACACCTAAGTATTCAGCGTTTTTAAGTGTGGGT
ATTGTTTCGGTGGAAATGGTTATGATTTTATTTATTGTGAAAGATGGATGGAATATAGTGAAAACGATTGCGATGCCGAT
GATTTTTGTAAATGGTTTTGGTAGTTTTATTTTACTTTCCATGGTGCAAGCAATTTTGCGACAGGAAGAGAATGCAAAGG
CATTACAAACGCATAAAGTGCTTCGAATTGCTGATAAAACATTACCTTACTTTCGTCAAGGGTTGACAGAAGAATCATGT
AAACATGTGGCACAAATTATCCATCGTTTTACGGGAACGGATGCGGTATCCTTAACAGATACAAAAAAAATATTAGCGCA
TGTGGGATTAGCATCGGATCATCATATCCCTTCGCATAGTTTAATTACGGGATTATCAAAAAAAGTATTACATACAGGGA
AAATAATGAAGGCGAAATCAAGAGAAGTCATTAACTGTCAGCATGAAGACTGTCCATTACAAGCGGCAATTGTTATTCCT
TTAACATCGCACGGCAATACAATTGGGACATTAAAGTTATATTTTAAAAATCCAAATCAGTTAAGTCGTGTAGAAGAGGA
ACTAGCAGAAGGATTAGCAAAAATTTTCTCGACCCAGCTTGAATTAGGGGAAGCAGAGCTGCAAAGTAAATTGCTTCAAG
ATGCTGAAATCAAAGCGTTACAAGCACAAATTAACCCACATTTCTTATTTAATGCGATTAATACAGTTTCAGCACTTTGT
CGTACAGATGTAGAAAAAGCAAGGAAGCTCTTACTACAGCTTAGCGTCTATTTTCGTTGTAACTTACAAGGAGCGCGGCA
GCTGTTGATTCCACTAGAGCAAGAGCTGAATCATGTGAATGCGTATTTATCGTTAGAGCAAGCGAGATTTCCAAATAAAT
ATGAGGTTAAAACCTATATAGACGAAGGATTAAAGACAATGTTAATTCCACCATTTGTGCTTCAATTGTTAGTTGAAAAT
GCTCTTAGACATGCATTTCCGAAGAAGCAACCGATTTGCCAAGTAGAAGTGTATGCGCACGTTGAAGATGATTTGATTCA
TTTTAAAGTGAAGGATAACGGTCAGGGGATTGAACAAGAGCGTTTAGAACAATTAGGAAAAGCTGTTGTAACATCCAAAA
AAGGAACAGGTACAGCTTTATATAACATTAACGAACGGTTAATAGGGTTATTTGGGAAAGAAACGACACTTCATATTCAA
AGTGAATTACAGAAAGGAACCGAAGTTTTCTTTGCAATTCCGATTCAATATGTAGAGGGGGAAGGAAGTAGTGGTAAAGG
TATTAGTAGTAGATGA

Upstream 100 bases:

>100_bases
ATTATTGTGAAAGATTATAAATGATAGATGATTTTCCTTGACGTTCACTTCATTATTTTTCGATAATAAAATGAACAAAA
TAAATAAAGGAGGACTAAAG

Downstream 100 bases:

>100_bases
TGAAATGTTAGCAAGAGATGAGCTGAAATATTTATTACAACGAACGAAAGAAGTAGATGAAATTGAAGAGGCAGATTGTA
TAGAAGATGCTTTAGAAATA

Product: signal transduction histidine kinase, LytS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 591; Mature: 591

Protein sequence:

>591_residues
MLDLVLMMIERVGLIVILGFLLSHIRIFRHLLHKQDGYKDKLMLICIFSLFTIVSNYTGIEIAGNTIMNENWLQGVSSSS
TIANTRIMGVGISGLLGGPIVGIGVGFISGIHRYMLGGTTAFSCAISSILAGIITGYIGRIFQKHNRTVTPKYSAFLSVG
IVSVEMVMILFIVKDGWNIVKTIAMPMIFVNGFGSFILLSMVQAILRQEENAKALQTHKVLRIADKTLPYFRQGLTEESC
KHVAQIIHRFTGTDAVSLTDTKKILAHVGLASDHHIPSHSLITGLSKKVLHTGKIMKAKSREVINCQHEDCPLQAAIVIP
LTSHGNTIGTLKLYFKNPNQLSRVEEELAEGLAKIFSTQLELGEAELQSKLLQDAEIKALQAQINPHFLFNAINTVSALC
RTDVEKARKLLLQLSVYFRCNLQGARQLLIPLEQELNHVNAYLSLEQARFPNKYEVKTYIDEGLKTMLIPPFVLQLLVEN
ALRHAFPKKQPICQVEVYAHVEDDLIHFKVKDNGQGIEQERLEQLGKAVVTSKKGTGTALYNINERLIGLFGKETTLHIQ
SELQKGTEVFFAIPIQYVEGEGSSGKGISSR

Sequences:

>Translated_591_residues
MLDLVLMMIERVGLIVILGFLLSHIRIFRHLLHKQDGYKDKLMLICIFSLFTIVSNYTGIEIAGNTIMNENWLQGVSSSS
TIANTRIMGVGISGLLGGPIVGIGVGFISGIHRYMLGGTTAFSCAISSILAGIITGYIGRIFQKHNRTVTPKYSAFLSVG
IVSVEMVMILFIVKDGWNIVKTIAMPMIFVNGFGSFILLSMVQAILRQEENAKALQTHKVLRIADKTLPYFRQGLTEESC
KHVAQIIHRFTGTDAVSLTDTKKILAHVGLASDHHIPSHSLITGLSKKVLHTGKIMKAKSREVINCQHEDCPLQAAIVIP
LTSHGNTIGTLKLYFKNPNQLSRVEEELAEGLAKIFSTQLELGEAELQSKLLQDAEIKALQAQINPHFLFNAINTVSALC
RTDVEKARKLLLQLSVYFRCNLQGARQLLIPLEQELNHVNAYLSLEQARFPNKYEVKTYIDEGLKTMLIPPFVLQLLVEN
ALRHAFPKKQPICQVEVYAHVEDDLIHFKVKDNGQGIEQERLEQLGKAVVTSKKGTGTALYNINERLIGLFGKETTLHIQ
SELQKGTEVFFAIPIQYVEGEGSSGKGISSR
>Mature_591_residues
MLDLVLMMIERVGLIVILGFLLSHIRIFRHLLHKQDGYKDKLMLICIFSLFTIVSNYTGIEIAGNTIMNENWLQGVSSSS
TIANTRIMGVGISGLLGGPIVGIGVGFISGIHRYMLGGTTAFSCAISSILAGIITGYIGRIFQKHNRTVTPKYSAFLSVG
IVSVEMVMILFIVKDGWNIVKTIAMPMIFVNGFGSFILLSMVQAILRQEENAKALQTHKVLRIADKTLPYFRQGLTEESC
KHVAQIIHRFTGTDAVSLTDTKKILAHVGLASDHHIPSHSLITGLSKKVLHTGKIMKAKSREVINCQHEDCPLQAAIVIP
LTSHGNTIGTLKLYFKNPNQLSRVEEELAEGLAKIFSTQLELGEAELQSKLLQDAEIKALQAQINPHFLFNAINTVSALC
RTDVEKARKLLLQLSVYFRCNLQGARQLLIPLEQELNHVNAYLSLEQARFPNKYEVKTYIDEGLKTMLIPPFVLQLLVEN
ALRHAFPKKQPICQVEVYAHVEDDLIHFKVKDNGQGIEQERLEQLGKAVVTSKKGTGTALYNINERLIGLFGKETTLHIQ
SELQKGTEVFFAIPIQYVEGEGSSGKGISSR

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=584, Percent_Identity=34.7602739726027, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI1788446, Length=582, Percent_Identity=31.9587628865979, Blast_Score=269, Evalue=4e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR005467
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF01590 GAF; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65551; Mature: 65551

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLVLMMIERVGLIVILGFLLSHIRIFRHLLHKQDGYKDKLMLICIFSLFTIVSNYTGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCE
EIAGNTIMNENWLQGVSSSSTIANTRIMGVGISGLLGGPIVGIGVGFISGIHRYMLGGTT
EEECCCCCCCHHHCCCCCCCCHHHCEEEEECHHHHCCCCHHHHHHHHHHHHHHHHHCCCH
AFSCAISSILAGIITGYIGRIFQKHNRTVTPKYSAFLSVGIVSVEMVMILFIVKDGWNIV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
KTIAMPMIFVNGFGSFILLSMVQAILRQEENAKALQTHKVLRIADKTLPYFRQGLTEESC
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
KHVAQIIHRFTGTDAVSLTDTKKILAHVGLASDHHIPSHSLITGLSKKVLHTGKIMKAKS
HHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCHHHHCCC
REVINCQHEDCPLQAAIVIPLTSHGNTIGTLKLYFKNPNQLSRVEEELAEGLAKIFSTQL
CCCCCCCCCCCCCEEEEEEEEECCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
ELGEAELQSKLLQDAEIKALQAQINPHFLFNAINTVSALCRTDVEKARKLLLQLSVYFRC
HCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
NLQGARQLLIPLEQELNHVNAYLSLEQARFPNKYEVKTYIDEGLKTMLIPPFVLQLLVEN
CCCHHHHHHHHHHHHHHHHHHHEEHHHHCCCCCCHHHHHHHCCHHHHCCHHHHHHHHHHH
ALRHAFPKKQPICQVEVYAHVEDDLIHFKVKDNGQGIEQERLEQLGKAVVTSKKGTGTAL
HHHHCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEE
YNINERLIGLFGKETTLHIQSELQKGTEVFFAIPIQYVEGEGSSGKGISSR
EECCHHHHHHHCCCEEEEEHHHHCCCCEEEEEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MLDLVLMMIERVGLIVILGFLLSHIRIFRHLLHKQDGYKDKLMLICIFSLFTIVSNYTGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCE
EIAGNTIMNENWLQGVSSSSTIANTRIMGVGISGLLGGPIVGIGVGFISGIHRYMLGGTT
EEECCCCCCCHHHCCCCCCCCHHHCEEEEECHHHHCCCCHHHHHHHHHHHHHHHHHCCCH
AFSCAISSILAGIITGYIGRIFQKHNRTVTPKYSAFLSVGIVSVEMVMILFIVKDGWNIV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
KTIAMPMIFVNGFGSFILLSMVQAILRQEENAKALQTHKVLRIADKTLPYFRQGLTEESC
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
KHVAQIIHRFTGTDAVSLTDTKKILAHVGLASDHHIPSHSLITGLSKKVLHTGKIMKAKS
HHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCHHHHCCC
REVINCQHEDCPLQAAIVIPLTSHGNTIGTLKLYFKNPNQLSRVEEELAEGLAKIFSTQL
CCCCCCCCCCCCCEEEEEEEEECCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
ELGEAELQSKLLQDAEIKALQAQINPHFLFNAINTVSALCRTDVEKARKLLLQLSVYFRC
HCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
NLQGARQLLIPLEQELNHVNAYLSLEQARFPNKYEVKTYIDEGLKTMLIPPFVLQLLVEN
CCCHHHHHHHHHHHHHHHHHHHEEHHHHCCCCCCHHHHHHHCCHHHHCCHHHHHHHHHHH
ALRHAFPKKQPICQVEVYAHVEDDLIHFKVKDNGQGIEQERLEQLGKAVVTSKKGTGTAL
HHHHCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEE
YNINERLIGLFGKETTLHIQSELQKGTEVFFAIPIQYVEGEGSSGKGISSR
EECCHHHHHHHCCCEEEEEHHHHCCCCEEEEEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]