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The map label for this gene is fhuG [H]

Identifier: 152977565

GI number: 152977565

Start: 3958270

End: 3959286

Strand: Reverse

Name: fhuG [H]

Synonym: Bcer98_3903

Alternate gene names: 152977565

Gene position: 3959286-3958270 (Counterclockwise)

Preceding gene: 152977566

Following gene: 152977564

Centisome position: 96.87

GC content: 38.74

Gene sequence:

>1017_bases
GTGAGGACAAGTATTTTAACAAAAAAGAACATTTCTGTTTTAACGATTATAGCGGGGTTAATTGTGTCCGTATTTTTCAT
TAGTTTAAATACAGGGACATTTAAAATACCGCCGATAGATGTATTGAAATCGTTAGTAGGATTAGGGGTTGAAGAGCAAT
CCGTTATTTTATTTGAATTTCGTATGCCTCGAATGGTTATTGCTATTTTAGTGGGTTCAGCATTAGCGATATCAGGGGCA
ATCATGCAAGGTTTATCAAGAAATCCACTTGCTGACCCTGGAATTATCGGTATTAATGCTGGAGCAGGATTGACAGTTGT
AGTTTTCGTCTATTTCTTCTTTGGAAAAGTAGGAACCGGTACGTTCTTATCCGTATTCATCCTTCCATTTTTTGCTTTGG
TTGGTGCGATATTGGCAGCAGTTATTATTTATACACTTGCATGGAAAAATGGCGTTTCATCAACGCGTCTTATTCTTGTT
GGGATTGCAGTGGCAGCAGGATTTGGAGCGGTTAGTTTAATTTTCTCCATGAAGATGACTTCGAATGACTTTCGCTTTGC
AACGATTTGGTTAGCAGGTAGTTTATGGGGGACGGATTGGAAGTTTGTATTAAGTGTGCTTCCATGGATGCTCATTTTTT
TACCGATTGCAATCCGAAAGGCTCATGTACTGAATGTCATGAATTTAGGTGATGCAGCGGCAGTCGGTCTCGGTGTCAAT
GTTGAGAAAGAAAGACGTAAATTATTATTTATTGCTGTTTGTTTAGCTGGTGCATCTGTAGCTGTTGCAGGTGGAATTGG
GTTTATCGGATTGATGGCACCACACTTAGCAAGGCGCCTTGTCGGAGGGAAGCACCAAATTATGTTACCGACAGCAGCAT
TAATTGGAACTTTTCTGTTATTGTTTGCAGATTTGATTTCTAGAAGTGTACTCACAACTTCAGAAATACCAGTAGGTCTT
GTTATTTCTGTTATTGGTGCACCATATTTCATTTATTTACTTATGAGGACAAAATAA

Upstream 100 bases:

>100_bases
TTATCAATCCTCCATTTGAAACACCAATTGGTGCGATTACAGCCTTAATCGGTGTTCCATTCTTCCTTTACTTAGCTCGT
AATGAAGGGAGAGGAAAAAT

Downstream 100 bases:

>100_bases
AGGGAGGCGCGTTTTGAATGGTGACTTTAGCAGTTGATTCGGTATCCGTTGGCTACAATGAAGGATTAATTATTGATGGA
TTATCAGTGGAAATTCCCGA

Product: transport system permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MRTSILTKKNISVLTIIAGLIVSVFFISLNTGTFKIPPIDVLKSLVGLGVEEQSVILFEFRMPRMVIAILVGSALAISGA
IMQGLSRNPLADPGIIGINAGAGLTVVVFVYFFFGKVGTGTFLSVFILPFFALVGAILAAVIIYTLAWKNGVSSTRLILV
GIAVAAGFGAVSLIFSMKMTSNDFRFATIWLAGSLWGTDWKFVLSVLPWMLIFLPIAIRKAHVLNVMNLGDAAAVGLGVN
VEKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFADLISRSVLTTSEIPVGL
VISVIGAPYFIYLLMRTK

Sequences:

>Translated_338_residues
MRTSILTKKNISVLTIIAGLIVSVFFISLNTGTFKIPPIDVLKSLVGLGVEEQSVILFEFRMPRMVIAILVGSALAISGA
IMQGLSRNPLADPGIIGINAGAGLTVVVFVYFFFGKVGTGTFLSVFILPFFALVGAILAAVIIYTLAWKNGVSSTRLILV
GIAVAAGFGAVSLIFSMKMTSNDFRFATIWLAGSLWGTDWKFVLSVLPWMLIFLPIAIRKAHVLNVMNLGDAAAVGLGVN
VEKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFADLISRSVLTTSEIPVGL
VISVIGAPYFIYLLMRTK
>Mature_338_residues
MRTSILTKKNISVLTIIAGLIVSVFFISLNTGTFKIPPIDVLKSLVGLGVEEQSVILFEFRMPRMVIAILVGSALAISGA
IMQGLSRNPLADPGIIGINAGAGLTVVVFVYFFFGKVGTGTFLSVFILPFFALVGAILAAVIIYTLAWKNGVSSTRLILV
GIAVAAGFGAVSLIFSMKMTSNDFRFATIWLAGSLWGTDWKFVLSVLPWMLIFLPIAIRKAHVLNVMNLGDAAAVGLGVN
VEKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFADLISRSVLTTSEIPVGL
VISVIGAPYFIYLLMRTK

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=313, Percent_Identity=37.0607028753994, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1786804, Length=328, Percent_Identity=35.0609756097561, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788004, Length=289, Percent_Identity=35.2941176470588, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1790741, Length=283, Percent_Identity=32.8621908127208, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786805, Length=313, Percent_Identity=35.4632587859425, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1786347, Length=288, Percent_Identity=34.375, Blast_Score=122, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35955; Mature: 35955

Theoretical pI: Translated: 11.01; Mature: 11.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTSILTKKNISVLTIIAGLIVSVFFISLNTGTFKIPPIDVLKSLVGLGVEEQSVILFEF
CCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCEEECCCHHHHHHHHCCCCCCCCEEEEEE
RMPRMVIAILVGSALAISGAIMQGLSRNPLADPGIIGINAGAGLTVVVFVYFFFGKVGTG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCH
TFLSVFILPFFALVGAILAAVIIYTLAWKNGVSSTRLILVGIAVAAGFGAVSLIFSMKMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SNDFRFATIWLAGSLWGTDWKFVLSVLPWMLIFLPIAIRKAHVLNVMNLGDAAAVGLGVN
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEECCCC
VEKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLL
CHHHHHHHHHHHHHHCCCHHEECCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
LFADLISRSVLTTSEIPVGLVISVIGAPYFIYLLMRTK
HHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHEEEECC
>Mature Secondary Structure
MRTSILTKKNISVLTIIAGLIVSVFFISLNTGTFKIPPIDVLKSLVGLGVEEQSVILFEF
CCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCEEECCCHHHHHHHHCCCCCCCCEEEEEE
RMPRMVIAILVGSALAISGAIMQGLSRNPLADPGIIGINAGAGLTVVVFVYFFFGKVGTG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCH
TFLSVFILPFFALVGAILAAVIIYTLAWKNGVSSTRLILVGIAVAAGFGAVSLIFSMKMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SNDFRFATIWLAGSLWGTDWKFVLSVLPWMLIFLPIAIRKAHVLNVMNLGDAAAVGLGVN
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEECCCC
VEKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLL
CHHHHHHHHHHHHHHCCCHHEECCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
LFADLISRSVLTTSEIPVGLVISVIGAPYFIYLLMRTK
HHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]