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The map label for this gene is fhuB [H]

Identifier: 152977566

GI number: 152977566

Start: 3959283

End: 3960335

Strand: Reverse

Name: fhuB [H]

Synonym: Bcer98_3904

Alternate gene names: 152977566

Gene position: 3960335-3959283 (Counterclockwise)

Preceding gene: 152977567

Following gene: 152977565

Centisome position: 96.9

GC content: 41.12

Gene sequence:

>1053_bases
ATGGGAGCAAGTGCGAGGAGTATAGAGCAGCAAGTAAATATAAAAGAGATTAAGAGCAGACCGCTTATTGCTTCTATTAT
TTTAATAGCAGGCACGATTTTGTTGGCTATAAGCATGGCAGTTTCCATTTCATTTGGAGCTGCAGATATTAGCTTAAAGA
CGGTATGGCAAGCTGTTTTTCAATTCGATAATTTATTGACACATCATAATGTCATTTGGGAGCTTCGCATGCCAAGAGCA
ATTGGAGGCGTAGTTGCAGGTGCGTTTCTAGCAGTATCAGGAGCAATTATGCAAGGGATGACGCGAAATCCGCTTGCATC
GCCATCTTTAATGGGAATTACAGATGGAGCAGTATTTGGAATTGCGATTATGTATGCGTTTTTTCCAAATTCACCATACT
TAATGTTTGTGATTGCTTCGTTTGTTGGAGCGGCATTTGGTGCAAGTATTGTATACGGTGTGGGAGCTTCCTCACCAGGA
GGACTAACACCTGTTAAGTTAGCGCTAGCTGGAGCGGCAATTAGCGCCCTGCTTGGTGCCATCTCATCTGGTATCGCCCT
TTATTTTAATCTCGCTCAAGAAGTAAGTATGTGGAATGCAGGTGGCGTTTCAGGGGTGAAATGGGCAAGTATTAATATGT
TGTTACCAATTGGACTTGTTTGTCTTGTTCTAGCAATTATAATGTCTAGATACATTACAATCTTAAGCTTCGGTGAAGAA
ATTGCGATCGGACTTGGACAAAATACAACTTTAATTAAATTTATTGGAACTGTAATTGTCCTTGTTTTAACAGGATCAGC
CGTATCGATGGCCGGATCAGTCGGGTTTGTAGGTCTTGTGATTCCACATATGACACGCTTTCTCGTTGGGTCTGATTATA
GATGGGTCATTCCATGTTCCGCTGTATTAGGTGGCTTATTAATTGAATGTGCAGATATGTTATCTCGCATTATCAATCCT
CCATTTGAAACACCAATTGGTGCGATTACAGCCTTAATCGGTGTTCCATTCTTCCTTTACTTAGCTCGTAATGAAGGGAG
AGGAAAAATGTGA

Upstream 100 bases:

>100_bases
AATCATTATCAAAAAAGTAAGGAAGTCAATATTCTTTTTATTATTTCTTGAGAATCAATCTCATTTTGTTACATATATTA
TTGGTTAGGATGGTTGAGGG

Downstream 100 bases:

>100_bases
GGACAAGTATTTTAACAAAAAAGAACATTTCTGTTTTAACGATTATAGCGGGGTTAATTGTGTCCGTATTTTTCATTAGT
TTAAATACAGGGACATTTAA

Product: transport system permease protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein B; Ferrichrome transport system permease protein fhuB; Iron(III)-hydroxamate import system permease protein fhuB [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MGASARSIEQQVNIKEIKSRPLIASIILIAGTILLAISMAVSISFGAADISLKTVWQAVFQFDNLLTHHNVIWELRMPRA
IGGVVAGAFLAVSGAIMQGMTRNPLASPSLMGITDGAVFGIAIMYAFFPNSPYLMFVIASFVGAAFGASIVYGVGASSPG
GLTPVKLALAGAAISALLGAISSGIALYFNLAQEVSMWNAGGVSGVKWASINMLLPIGLVCLVLAIIMSRYITILSFGEE
IAIGLGQNTTLIKFIGTVIVLVLTGSAVSMAGSVGFVGLVIPHMTRFLVGSDYRWVIPCSAVLGGLLIECADMLSRIINP
PFETPIGAITALIGVPFFLYLARNEGRGKM

Sequences:

>Translated_350_residues
MGASARSIEQQVNIKEIKSRPLIASIILIAGTILLAISMAVSISFGAADISLKTVWQAVFQFDNLLTHHNVIWELRMPRA
IGGVVAGAFLAVSGAIMQGMTRNPLASPSLMGITDGAVFGIAIMYAFFPNSPYLMFVIASFVGAAFGASIVYGVGASSPG
GLTPVKLALAGAAISALLGAISSGIALYFNLAQEVSMWNAGGVSGVKWASINMLLPIGLVCLVLAIIMSRYITILSFGEE
IAIGLGQNTTLIKFIGTVIVLVLTGSAVSMAGSVGFVGLVIPHMTRFLVGSDYRWVIPCSAVLGGLLIECADMLSRIINP
PFETPIGAITALIGVPFFLYLARNEGRGKM
>Mature_349_residues
GASARSIEQQVNIKEIKSRPLIASIILIAGTILLAISMAVSISFGAADISLKTVWQAVFQFDNLLTHHNVIWELRMPRAI
GGVVAGAFLAVSGAIMQGMTRNPLASPSLMGITDGAVFGIAIMYAFFPNSPYLMFVIASFVGAAFGASIVYGVGASSPGG
LTPVKLALAGAAISALLGAISSGIALYFNLAQEVSMWNAGGVSGVKWASINMLLPIGLVCLVLAIIMSRYITILSFGEEI
AIGLGQNTTLIKFIGTVIVLVLTGSAVSMAGSVGFVGLVIPHMTRFLVGSDYRWVIPCSAVLGGLLIECADMLSRIINPP
FETPIGAITALIGVPFFLYLARNEGRGKM

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=280, Percent_Identity=35.7142857142857, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1790740, Length=317, Percent_Identity=32.4921135646688, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1790741, Length=278, Percent_Identity=37.0503597122302, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1786347, Length=347, Percent_Identity=29.971181556196, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788004, Length=280, Percent_Identity=31.4285714285714, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786804, Length=335, Percent_Identity=28.0597014925373, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36543; Mature: 36412

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGASARSIEQQVNIKEIKSRPLIASIILIAGTILLAISMAVSISFGAADISLKTVWQAVF
CCCCHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHH
QFDNLLTHHNVIWELRMPRAIGGVVAGAFLAVSGAIMQGMTRNPLASPSLMGITDGAVFG
HHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
IAIMYAFFPNSPYLMFVIASFVGAAFGASIVYGVGASSPGGLTPVKLALAGAAISALLGA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
ISSGIALYFNLAQEVSMWNAGGVSGVKWASINMLLPIGLVCLVLAIIMSRYITILSFGEE
HHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
IAIGLGQNTTLIKFIGTVIVLVLTGSAVSMAGSVGFVGLVIPHMTRFLVGSDYRWVIPCS
HEEECCCCCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEHH
AVLGGLLIECADMLSRIINPPFETPIGAITALIGVPFFLYLARNEGRGKM
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GASARSIEQQVNIKEIKSRPLIASIILIAGTILLAISMAVSISFGAADISLKTVWQAVF
CCCHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHH
QFDNLLTHHNVIWELRMPRAIGGVVAGAFLAVSGAIMQGMTRNPLASPSLMGITDGAVFG
HHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
IAIMYAFFPNSPYLMFVIASFVGAAFGASIVYGVGASSPGGLTPVKLALAGAAISALLGA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
ISSGIALYFNLAQEVSMWNAGGVSGVKWASINMLLPIGLVCLVLAIIMSRYITILSFGEE
HHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
IAIGLGQNTTLIKFIGTVIVLVLTGSAVSMAGSVGFVGLVIPHMTRFLVGSDYRWVIPCS
HEEECCCCCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEHH
AVLGGLLIECADMLSRIINPPFETPIGAITALIGVPFFLYLARNEGRGKM
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377; 8388528 [H]