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The map label for this gene is murA2 [H]

Identifier: 152977520

GI number: 152977520

Start: 3912992

End: 3914281

Strand: Reverse

Name: murA2 [H]

Synonym: Bcer98_3855

Alternate gene names: 152977520

Gene position: 3914281-3912992 (Counterclockwise)

Preceding gene: 152977521

Following gene: 152977519

Centisome position: 95.77

GC content: 41.47

Gene sequence:

>1290_bases
ATGGAAAAGTTGCTGATTGAAGGTGGAAGACCTTTAAATGGATCAATTCGCGTGAGCGGTGCAAAGAACAGTGCTGTCGC
TCTAATTCCAGCGACAATTTTGGCTGATACTCCAGTAACCATTGGTGGTGTGCCTAATATCTCAGATGTAAAAATGTTAG
GGGACTTATTAGAGGAAATTGGAGGAACTGTAACGTATGGGCAAGAGGAAGAGATGATTGTTGATCCTTCCCAAATGGTT
GCCATGCCTTTGCCAAATGGAAAAGTAAAAAAATTGCGTGCTTCATACTATTTGATGGGCGCTATGCTTGGCCGTTTCAA
AAAAGCTGTAATTGGGCTTCCTGGTGGATGTCACTTAGGGCCAAGACCAATTGATCAGCACATTAAAGGGTTTGAAGCGT
TAGGTGCACACGTAACAAATGAACAAGGTGCTATCTATTTAAGAGCGGATGAGCTGTGTGGGGCGCGAATTTATTTAGAT
GTAGTAAGCGTCGGAGCAACCATTAATATTATGCTAGCAGCTGTAAGGGCAAAAGGTAGAACGATAATTGAAAATGCAGC
AAAAGAACCGGAAATTATTGATGTAGCTACTTTATTGACAAGTATGGGCGCTCGAATTAAAGGCGCTGGTACAGATGTCA
TTCGTATCGATGGCGTAGAGTCTCTGCATGGATGTCACCATACGATTATTCCTGATCGCATTGAAGCTGGGACATATATG
ATTTTAGGTGCTGCTTCTGGTGGCGAAGTAACGGTTGATAATGTGATTCCGCAGCATTTAGAATCTGTTACGGCAAAGCT
GAGGGAAGCTGGTGTACAAGTTGAAACGCATGATGATCAAATTAAAGTAAATGGAAATCGCAAATTAAAAACAGTGGATA
TAAAGACATTAGTATATCCAGGGTTTCCAACAGATTTGCAACAACCTTTTACAACGCTTTTAACGAAAGCATATGGTACA
GGTGTTGTAACAGATACAATTTACGGAGCACGCTTTAAACATATTGATGAGCTGCGCCGAATGAATGCGAAAATTAAGGT
AGAAGGTCGTTCTGCGATTGTAACAGGACCTGTATCACTGCAAGGTGCAAAAGTGAAAGCAAGTGACTTACGGGCAGGAG
CAGCACTTATTATTGCTGGTTTAATGGCAGATGGAATTACAGAAGTAACAGGACTTGAACATATAGACCGGGGTTATGAA
AATATAGTAGACAAGCTTAAGGGGCTTGGTGCGAACATTTGGCGAGAACAAATGACGCAGCAAGAAATTGAAGAAATGAA
GAATGCATAA

Upstream 100 bases:

>100_bases
CTTGTTAAGTTCAGACTAAAATAAAATGTTTTACATAGTTTGTTGACCAAGTGGGGGATTCTTAAGGAAAGTAAATACAT
TCACAGGAAGGGAGCTCAAC

Downstream 100 bases:

>100_bases
CATGTATTGTCATTATATGACGAAAAAGGTAATATGTAGTACTTTTGTTAATGAAGAACGAAGGGTTACGAGTAACAGAA
ACGGTACTTGATAGAAAAAG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2 [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MEKLLIEGGRPLNGSIRVSGAKNSAVALIPATILADTPVTIGGVPNISDVKMLGDLLEEIGGTVTYGQEEEMIVDPSQMV
AMPLPNGKVKKLRASYYLMGAMLGRFKKAVIGLPGGCHLGPRPIDQHIKGFEALGAHVTNEQGAIYLRADELCGARIYLD
VVSVGATINIMLAAVRAKGRTIIENAAKEPEIIDVATLLTSMGARIKGAGTDVIRIDGVESLHGCHHTIIPDRIEAGTYM
ILGAASGGEVTVDNVIPQHLESVTAKLREAGVQVETHDDQIKVNGNRKLKTVDIKTLVYPGFPTDLQQPFTTLLTKAYGT
GVVTDTIYGARFKHIDELRRMNAKIKVEGRSAIVTGPVSLQGAKVKASDLRAGAALIIAGLMADGITEVTGLEHIDRGYE
NIVDKLKGLGANIWREQMTQQEIEEMKNA

Sequences:

>Translated_429_residues
MEKLLIEGGRPLNGSIRVSGAKNSAVALIPATILADTPVTIGGVPNISDVKMLGDLLEEIGGTVTYGQEEEMIVDPSQMV
AMPLPNGKVKKLRASYYLMGAMLGRFKKAVIGLPGGCHLGPRPIDQHIKGFEALGAHVTNEQGAIYLRADELCGARIYLD
VVSVGATINIMLAAVRAKGRTIIENAAKEPEIIDVATLLTSMGARIKGAGTDVIRIDGVESLHGCHHTIIPDRIEAGTYM
ILGAASGGEVTVDNVIPQHLESVTAKLREAGVQVETHDDQIKVNGNRKLKTVDIKTLVYPGFPTDLQQPFTTLLTKAYGT
GVVTDTIYGARFKHIDELRRMNAKIKVEGRSAIVTGPVSLQGAKVKASDLRAGAALIIAGLMADGITEVTGLEHIDRGYE
NIVDKLKGLGANIWREQMTQQEIEEMKNA
>Mature_429_residues
MEKLLIEGGRPLNGSIRVSGAKNSAVALIPATILADTPVTIGGVPNISDVKMLGDLLEEIGGTVTYGQEEEMIVDPSQMV
AMPLPNGKVKKLRASYYLMGAMLGRFKKAVIGLPGGCHLGPRPIDQHIKGFEALGAHVTNEQGAIYLRADELCGARIYLD
VVSVGATINIMLAAVRAKGRTIIENAAKEPEIIDVATLLTSMGARIKGAGTDVIRIDGVESLHGCHHTIIPDRIEAGTYM
ILGAASGGEVTVDNVIPQHLESVTAKLREAGVQVETHDDQIKVNGNRKLKTVDIKTLVYPGFPTDLQQPFTTLLTKAYGT
GVVTDTIYGARFKHIDELRRMNAKIKVEGRSAIVTGPVSLQGAKVKASDLRAGAALIIAGLMADGITEVTGLEHIDRGYE
NIVDKLKGLGANIWREQMTQQEIEEMKNA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=417, Percent_Identity=44.3645083932854, Blast_Score=346, Evalue=1e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45864; Mature: 45864

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLLIEGGRPLNGSIRVSGAKNSAVALIPATILADTPVTIGGVPNISDVKMLGDLLEEI
CCCEEECCCCCCCCCEEEECCCCCEEEEEEHHHHCCCCEEECCCCCHHHHHHHHHHHHHH
GGTVTYGQEEEMIVDPSQMVAMPLPNGKVKKLRASYYLMGAMLGRFKKAVIGLPGGCHLG
CCEEECCCCCCEEECHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PRPIDQHIKGFEALGAHVTNEQGAIYLRADELCGARIYLDVVSVGATINIMLAAVRAKGR
CCCHHHHHHHHHHHCCEEECCCCEEEEEECCCCCCEEEEEEHHCCCCEEEHHEEHHHCCC
TIIENAAKEPEIIDVATLLTSMGARIKGAGTDVIRIDGVESLHGCHHTIIPDRIEAGTYM
HHHHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEECCCHHHCCCCCCCCCCCCCCCCEE
ILGAASGGEVTVDNVIPQHLESVTAKLREAGVQVETHDDQIKVNGNRKLKTVDIKTLVYP
EEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEECCCCEEEEEEEEEEEEC
GFPTDLQQPFTTLLTKAYGTGVVTDTIYGARFKHIDELRRMNAKIKVEGRSAIVTGPVSL
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCEE
QGAKVKASDLRAGAALIIAGLMADGITEVTGLEHIDRGYENIVDKLKGLGANIWREQMTQ
CCCEEEHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QEIEEMKNA
HHHHHHHCC
>Mature Secondary Structure
MEKLLIEGGRPLNGSIRVSGAKNSAVALIPATILADTPVTIGGVPNISDVKMLGDLLEEI
CCCEEECCCCCCCCCEEEECCCCCEEEEEEHHHHCCCCEEECCCCCHHHHHHHHHHHHHH
GGTVTYGQEEEMIVDPSQMVAMPLPNGKVKKLRASYYLMGAMLGRFKKAVIGLPGGCHLG
CCEEECCCCCCEEECHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PRPIDQHIKGFEALGAHVTNEQGAIYLRADELCGARIYLDVVSVGATINIMLAAVRAKGR
CCCHHHHHHHHHHHCCEEECCCCEEEEEECCCCCCEEEEEEHHCCCCEEEHHEEHHHCCC
TIIENAAKEPEIIDVATLLTSMGARIKGAGTDVIRIDGVESLHGCHHTIIPDRIEAGTYM
HHHHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEECCCHHHCCCCCCCCCCCCCCCCEE
ILGAASGGEVTVDNVIPQHLESVTAKLREAGVQVETHDDQIKVNGNRKLKTVDIKTLVYP
EEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEECCCCEEEEEEEEEEEEC
GFPTDLQQPFTTLLTKAYGTGVVTDTIYGARFKHIDELRRMNAKIKVEGRSAIVTGPVSL
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCEE
QGAKVKASDLRAGAALIIAGLMADGITEVTGLEHIDRGYENIVDKLKGLGANIWREQMTQ
CCCEEEHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QEIEEMKNA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]