Click here to switch to the map view.

The map label for this gene is fba [H]

Identifier: 152977521

GI number: 152977521

Start: 3914637

End: 3915494

Strand: Reverse

Name: fba [H]

Synonym: Bcer98_3856

Alternate gene names: 152977521

Gene position: 3915494-3914637 (Counterclockwise)

Preceding gene: 152977522

Following gene: 152977520

Centisome position: 95.8

GC content: 38.93

Gene sequence:

>858_bases
ATGCCTTTAGTTTCCATGAAAGAAATGCTAAACAAAGCACTAGAAGGAAAATACGCAGTTGGTCAATTCAATATTAACAA
CTTAGAATGGACTCAAGCTATTTTAGCAGCTGCAGAAGAAGAAAAATCTCCTGTAATCCTAGGTGTATCTGAAGGTGCAG
CTCGTCATATGACTGGTTTCAAAACAGTTGTAGCTATGGTTAAAGCTTTAATCGAAGAAATGAACATCACTGTTCCTGTA
GCGATCCATCTTGATCATGGTTCAAGCTTTGAAAAATGTAAAGAAGCAATTGATGCAGGTTTCACATCTGTAATGATTGA
CGCTTCTCACCACCCATTTGAAGAAAACGTTGAAACTACTAAAAAAGTAGTAGAATACGCACATGCTCGTAACGTATCTG
TAGAAGCTGAACTTGGAACAGTTGGTGGGCAAGAAGACGACGTAATCGCTGATGGCATTATCTATGCTGATCCTGAAGAA
TGTAAACACCTTGTTGAAGCAACAGGTATCGATTGCCTAGCTCCAGCTTTAGGTTCTGTACACGGTCCTTACAAAGGTGA
GCCTAACTTAGGATTTAAAGAAATGGAACAAGTTCGTGACCTAACTGGTGTACCTTTAGTACTTCACGGTGGTACTGGTA
TCCCAACTGCTGATATCAAAAAAGCTATTTCTTTAGGTACTTCAAAAATCAATGTAAACACTGAAAACCAAATCGCGTTT
ACAAAAGCTGTTCGTGAAGTATTAAACAAAGACCAAGAAGTTTACGATCCTCGTAAATTTATCGGACCTGGCCGCGAAGC
TATCAAAGCAACTGTTATTGGTAAAATTCGTGAATTCGGTTCTAACGGTAAAGCGTAA

Upstream 100 bases:

>100_bases
AAGTCCGGTATGTTGATATACATAATCTTCCTTATTCTGGTCATACTACCAGCGATAAGAACTTATCGGATACAAAAAAC
GTTTTTTAGGAGGATTCACC

Downstream 100 bases:

>100_bases
GAATAAAATTCCGTTTTGGAAACCGTCTACTCTTTTAGACGGTTTCCTTTCGTTGTATAATGAAAGCGTGAACAAGTCTT
AAGATTAATTAAATTTCTAA

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MPLVSMKEMLNKALEGKYAVGQFNINNLEWTQAILAAAEEEKSPVILGVSEGAARHMTGFKTVVAMVKALIEEMNITVPV
AIHLDHGSSFEKCKEAIDAGFTSVMIDASHHPFEENVETTKKVVEYAHARNVSVEAELGTVGGQEDDVIADGIIYADPEE
CKHLVEATGIDCLAPALGSVHGPYKGEPNLGFKEMEQVRDLTGVPLVLHGGTGIPTADIKKAISLGTSKINVNTENQIAF
TKAVREVLNKDQEVYDPRKFIGPGREAIKATVIGKIREFGSNGKA

Sequences:

>Translated_285_residues
MPLVSMKEMLNKALEGKYAVGQFNINNLEWTQAILAAAEEEKSPVILGVSEGAARHMTGFKTVVAMVKALIEEMNITVPV
AIHLDHGSSFEKCKEAIDAGFTSVMIDASHHPFEENVETTKKVVEYAHARNVSVEAELGTVGGQEDDVIADGIIYADPEE
CKHLVEATGIDCLAPALGSVHGPYKGEPNLGFKEMEQVRDLTGVPLVLHGGTGIPTADIKKAISLGTSKINVNTENQIAF
TKAVREVLNKDQEVYDPRKFIGPGREAIKATVIGKIREFGSNGKA
>Mature_284_residues
PLVSMKEMLNKALEGKYAVGQFNINNLEWTQAILAAAEEEKSPVILGVSEGAARHMTGFKTVVAMVKALIEEMNITVPVA
IHLDHGSSFEKCKEAIDAGFTSVMIDASHHPFEENVETTKKVVEYAHARNVSVEAELGTVGGQEDDVIADGIIYADPEEC
KHLVEATGIDCLAPALGSVHGPYKGEPNLGFKEMEQVRDLTGVPLVLHGGTGIPTADIKKAISLGTSKINVNTENQIAFT
KAVREVLNKDQEVYDPRKFIGPGREAIKATVIGKIREFGSNGKA

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI87082041, Length=287, Percent_Identity=42.1602787456446, Blast_Score=233, Evalue=9e-63,
Organism=Escherichia coli, GI1789526, Length=286, Percent_Identity=40.9090909090909, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1788072, Length=285, Percent_Identity=42.1052631578947, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1789293, Length=338, Percent_Identity=26.6272189349112, Blast_Score=89, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6322790, Length=333, Percent_Identity=26.4264264264264, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 30691; Mature: 30560

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVSMKEMLNKALEGKYAVGQFNINNLEWTQAILAAAEEEKSPVILGVSEGAARHMTGF
CCCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
KTVVAMVKALIEEMNITVPVAIHLDHGSSFEKCKEAIDAGFTSVMIDASHHPFEENVETT
HHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHH
KKVVEYAHARNVSVEAELGTVGGQEDDVIADGIIYADPEECKHLVEATGIDCLAPALGSV
HHHHHHHHHCCCEEEEECCCCCCCCCCEEECCEEECCHHHHHHHHHHCCCHHHHHHHHCC
HGPYKGEPNLGFKEMEQVRDLTGVPLVLHGGTGIPTADIKKAISLGTSKINVNTENQIAF
CCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCEEECCCCCHHHH
TKAVREVLNKDQEVYDPRKFIGPGREAIKATVIGKIREFGSNGKA
HHHHHHHHCCCHHHCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PLVSMKEMLNKALEGKYAVGQFNINNLEWTQAILAAAEEEKSPVILGVSEGAARHMTGF
CCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
KTVVAMVKALIEEMNITVPVAIHLDHGSSFEKCKEAIDAGFTSVMIDASHHPFEENVETT
HHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHH
KKVVEYAHARNVSVEAELGTVGGQEDDVIADGIIYADPEECKHLVEATGIDCLAPALGSV
HHHHHHHHHCCCEEEEECCCCCCCCCCEEECCEEECCHHHHHHHHHHCCCHHHHHHHHCC
HGPYKGEPNLGFKEMEQVRDLTGVPLVLHGGTGIPTADIKKAISLGTSKINVNTENQIAF
CCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCEEECCCCCHHHH
TKAVREVLNKDQEVYDPRKFIGPGREAIKATVIGKIREFGSNGKA
HHHHHHHHCCCHHHCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA