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The map label for this gene is phoP [H]

Identifier: 152976971

GI number: 152976971

Start: 3342678

End: 3343394

Strand: Reverse

Name: phoP [H]

Synonym: Bcer98_3274

Alternate gene names: 152976971

Gene position: 3343394-3342678 (Counterclockwise)

Preceding gene: 152976972

Following gene: 152976970

Centisome position: 81.81

GC content: 37.24

Gene sequence:

>717_bases
ATGAGCAATCGAATTTTAGTTGTTGATGATGAAGAGTTTATCCTAACTTTAATTGAGTTTAATTTACAGCAGGCTGGTTT
TGAAGTGATCACAGCAATGGATGGTGAAGTTGCGTTTCAAAAGGCGACAACAGAGCGTCCAGATTTGATTATATTAGATT
TAATGCTTCCAAAGATGGATGGAATGGAAGTATGTAAGGAGTTACGTTTGCAGCGCGTTATGACACCTATTCTTATGCTA
ACTGCAAAAGATGATGAATTTGATAAAGTACTAGGGCTTGAGCTTGGAGCCGATGATTATATGACGAAGCCGTTTAGCCC
GAGGGAAGTTGTTGCACGAGTGAAGGCAATTTTACGTCGAACAAAGTTGCAGGAAGAACAAATTCCGGAAGTGCCAGATG
AAAATAGCATTATGATTTCTGAACTAAAGATTTTACCAGAATTTTATGAGGCATATTTCAGAGGAGAAAAATTAGAACTT
ACTCCGAAAGAGTTTGAATTACTTGTTTATCTTGCGAGGAATAAAGGGCGAGTATTAACGCGCGATCAATTATTAAGCGC
GGTATGGAATTATGATTTCGCTGGTGATACGAGAATTGTTGATGTTCATATTAGTCATCTGCGCGATAAAATAGAGCACA
ATACAAAAAAACCAGCGTATATTAAGACAATTCGAGGATTAGGTTATAAATTAGAGGAGCCAAAAGGAGATGAATAA

Upstream 100 bases:

>100_bases
ACAATTCTATTGAGAGGGGCTTTGTTTTCTAGTATGATGAGAATAACGGGGAAAATACTAGGATGAAGAAGGTTTCAAGT
CTATTACTTGGAGGAAGAGA

Downstream 100 bases:

>100_bases
ATTTCGCTCCAGGCTTCTTTTTACATTTGTTTCGCTTATTATTTTTATTTTAGTGGGACTTGGTGTACTGTTAGAGACGT
TGTTTGAGAATTATTATATC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MSNRILVVDDEEFILTLIEFNLQQAGFEVITAMDGEVAFQKATTERPDLIILDLMLPKMDGMEVCKELRLQRVMTPILML
TAKDDEFDKVLGLELGADDYMTKPFSPREVVARVKAILRRTKLQEEQIPEVPDENSIMISELKILPEFYEAYFRGEKLEL
TPKEFELLVYLARNKGRVLTRDQLLSAVWNYDFAGDTRIVDVHISHLRDKIEHNTKKPAYIKTIRGLGYKLEEPKGDE

Sequences:

>Translated_238_residues
MSNRILVVDDEEFILTLIEFNLQQAGFEVITAMDGEVAFQKATTERPDLIILDLMLPKMDGMEVCKELRLQRVMTPILML
TAKDDEFDKVLGLELGADDYMTKPFSPREVVARVKAILRRTKLQEEQIPEVPDENSIMISELKILPEFYEAYFRGEKLEL
TPKEFELLVYLARNKGRVLTRDQLLSAVWNYDFAGDTRIVDVHISHLRDKIEHNTKKPAYIKTIRGLGYKLEEPKGDE
>Mature_237_residues
SNRILVVDDEEFILTLIEFNLQQAGFEVITAMDGEVAFQKATTERPDLIILDLMLPKMDGMEVCKELRLQRVMTPILMLT
AKDDEFDKVLGLELGADDYMTKPFSPREVVARVKAILRRTKLQEEQIPEVPDENSIMISELKILPEFYEAYFRGEKLELT
PKEFELLVYLARNKGRVLTRDQLLSAVWNYDFAGDTRIVDVHISHLRDKIEHNTKKPAYIKTIRGLGYKLEEPKGDE

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=232, Percent_Identity=41.8103448275862, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=40.343347639485, Blast_Score=163, Evalue=8e-42,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=39.4736842105263, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=43.1718061674009, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=39.0557939914163, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=40.174672489083, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=37.3913043478261, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=35.7758620689655, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=34.2105263157895, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI87082012, Length=232, Percent_Identity=35.3448275862069, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=32.7659574468085, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787375, Length=235, Percent_Identity=34.0425531914894, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=32.618025751073, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=32.3275862068966, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788550, Length=124, Percent_Identity=33.0645161290323, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790299, Length=125, Percent_Identity=32, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787487, Length=104, Percent_Identity=29.8076923076923, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790437, Length=175, Percent_Identity=25.7142857142857, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27535; Mature: 27404

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRILVVDDEEFILTLIEFNLQQAGFEVITAMDGEVAFQKATTERPDLIILDLMLPKMD
CCCCEEEEECHHHHHHHHHHHHHHCCEEEEEECCCCCEEHHCCCCCCCEEEEEECCCCCC
GMEVCKELRLQRVMTPILMLTAKDDEFDKVLGLELGADDYMTKPFSPREVVARVKAILRR
HHHHHHHHHHHHHHHHHHEEEECCCCHHHHHCEEECCCCCCCCCCCHHHHHHHHHHHHHH
TKLQEEQIPEVPDENSIMISELKILPEFYEAYFRGEKLELTPKEFELLVYLARNKGRVLT
HHCCHHHCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCEEECHHHEEEEEEEECCCCCEEE
RDQLLSAVWNYDFAGDTRIVDVHISHLRDKIEHNTKKPAYIKTIRGLGYKLEEPKGDE
HHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHCCCCCCHHHHHHHHCCEECCCCCCCC
>Mature Secondary Structure 
SNRILVVDDEEFILTLIEFNLQQAGFEVITAMDGEVAFQKATTERPDLIILDLMLPKMD
CCCEEEEECHHHHHHHHHHHHHHCCEEEEEECCCCCEEHHCCCCCCCEEEEEECCCCCC
GMEVCKELRLQRVMTPILMLTAKDDEFDKVLGLELGADDYMTKPFSPREVVARVKAILRR
HHHHHHHHHHHHHHHHHHEEEECCCCHHHHHCEEECCCCCCCCCCCHHHHHHHHHHHHHH
TKLQEEQIPEVPDENSIMISELKILPEFYEAYFRGEKLELTPKEFELLVYLARNKGRVLT
HHCCHHHCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCEEECHHHEEEEEEEECCCCCEEE
RDQLLSAVWNYDFAGDTRIVDVHISHLRDKIEHNTKKPAYIKTIRGLGYKLEEPKGDE
HHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHCCCCCCHHHHHHHHCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]