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The map label for this gene is phoR [H]

Identifier: 152976970

GI number: 152976970

Start: 3340928

End: 3342685

Strand: Reverse

Name: phoR [H]

Synonym: Bcer98_3273

Alternate gene names: 152976970

Gene position: 3342685-3340928 (Counterclockwise)

Preceding gene: 152976971

Following gene: 152976969

Centisome position: 81.79

GC content: 35.04

Gene sequence:

>1758_bases
ATGAATAAATTTCGCTCCAGGCTTCTTTTTACATTTGTTTCGCTTATTATTTTTATTTTAGTGGGACTTGGTGTACTGTT
AGAGACGTTGTTTGAGAATTATTATATCGAGCATACGAAAGAGAGAACAGTAAAGGAAACAAGGTATGTTGCTTTATTAG
TAGAAGAGTTAGGTATTGATAAGGTCTTACATGCACAGAATGTTTTTACCGAATTAGAAGAACAAATACCGATTTCGATC
CTCTTTGTTGATGAAGCGAAAAAGGTTCAATATAGTAAGAGTGATAAGCCGGTGTTTGATCAAAAAATGATTGAGGAGCT
TACTTCTGAAACAGCCGGTCAAAAAAGTAAGGTTATTACAAAAGAATCAAAGCAGAGCAATGTATTTTACCATGCTGTAT
TTGTACAAGATGCGCAAGGAAAGCAAGGATATATTCTCGTGAAAAGTATAATTGAACCTTTAAAAGATGTTCATCAAAAA
ACATGGGGACTATTAATTGTTGGATTTGTAATTGCTTGTCTTGTAGTTATTTTTCTTGGAATGAAAATTACTGGACAGTA
TATTCGCCCGATAGAATCTGTTACAAAAGTAGCTATTGAGTTGGCTAAGGGAAATTATAAGGCAAGAGCGTATGAGAGTC
ATTCTGATGAAACAGGAATGTTAAGCAAGGCAATTAATATTTTAGCCCGTAATTTACAAGAGATGACGTTGGAGCAAGAA
ATGCAGCAAGATCGCTTACATACGCTGATTGAAAATATGGGAAGCGGTATGATTTTAATTGACAGCCGAGGATATATTAG
TCTTGTAAACCGTTCGTATAAAGAGATTTTTCATGTTACAGATGAAGAGTATTTGGATCGTTTATATTATGAATCGTTTC
ATCACACTGAGATTATTGAACTGGTAGAAGAGATCTTTATGACAGAAGTGAAAGTACGCAAACAAGTGCTGTTGCCGCTT
GATATTGAACGAAAGCATTTTGAAGTATATGGCGCACCTATTATTGGGACGAATCATGAGTGGAAAGGGATTGTACTTGT
ATTTCATGATATAACCGAATTAAAGAAACTTGAGCAAATGAGAAAAGACTTTTTAGCGAATGTTTCTCATGAATTGAAAA
CACCAATTACTTCTATTAAAGGATTTTCAGAAACATTGCTTGACGGAGCAATGAAGAATCAAAAATTTTGTGAGCATTTC
TTACACATTATTTTAAAAGAAAGTGAGCGTATGCAAGACTTGATTGAAGATTTGTTAGATTTGTCGAAAATCGAGCAACA
AGGCTTTAAATTAAATATGGGAAATGTGGATATAAAGGACTTGCTGGAAGATATTAAAATGGTGTTAGATAAAAAGGCAC
AAGATAAAGAGATTGTGTTACAGATGGATGCTATGCAGCATGTATCTGTTATTGGAGATTCCAGCCGCTTGAAGCAAATC
TTTATTAATTTAGTTCATAATGCAATTATATATACGCCTGTTGGTGGAACCGTTTCTGTTTCATTATTTGAGGACGAACA
GAATGCCTACGTGCAAGTAGCTGATACAGGAATTGGGATTAGTAAAGAAGAAATCCCACGAATCTTTGAGCGTTTTTATC
GTGTAGATAAGGCGCGAAGCCGAAATACAGGTGGAACAGGGCTTGGGCTATCTATTGTTAAACATTTAGTGGAAGCTCAT
CACGGAATGATTACTGTAGAAAGTAAAGTAGGGGAAGGGACAATGTTTACGGTCGCTTTACCAAAAGTAAATCTTTAG

Upstream 100 bases:

>100_bases
ATTAGTCATCTGCGCGATAAAATAGAGCACAATACAAAAAAACCAGCGTATATTAAGACAATTCGAGGATTAGGTTATAA
ATTAGAGGAGCCAAAAGGAG

Downstream 100 bases:

>100_bases
ATTTTGGTTGAGGGATATTTACATTATATTAACAATAGCTTCATTAAAGATTAACAAAGACCTGTTAATATAATACATGA
AAACCCCTTCATCCAAGGAG

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MNKFRSRLLFTFVSLIIFILVGLGVLLETLFENYYIEHTKERTVKETRYVALLVEELGIDKVLHAQNVFTELEEQIPISI
LFVDEAKKVQYSKSDKPVFDQKMIEELTSETAGQKSKVITKESKQSNVFYHAVFVQDAQGKQGYILVKSIIEPLKDVHQK
TWGLLIVGFVIACLVVIFLGMKITGQYIRPIESVTKVAIELAKGNYKARAYESHSDETGMLSKAINILARNLQEMTLEQE
MQQDRLHTLIENMGSGMILIDSRGYISLVNRSYKEIFHVTDEEYLDRLYYESFHHTEIIELVEEIFMTEVKVRKQVLLPL
DIERKHFEVYGAPIIGTNHEWKGIVLVFHDITELKKLEQMRKDFLANVSHELKTPITSIKGFSETLLDGAMKNQKFCEHF
LHIILKESERMQDLIEDLLDLSKIEQQGFKLNMGNVDIKDLLEDIKMVLDKKAQDKEIVLQMDAMQHVSVIGDSSRLKQI
FINLVHNAIIYTPVGGTVSVSLFEDEQNAYVQVADTGIGISKEEIPRIFERFYRVDKARSRNTGGTGLGLSIVKHLVEAH
HGMITVESKVGEGTMFTVALPKVNL

Sequences:

>Translated_585_residues
MNKFRSRLLFTFVSLIIFILVGLGVLLETLFENYYIEHTKERTVKETRYVALLVEELGIDKVLHAQNVFTELEEQIPISI
LFVDEAKKVQYSKSDKPVFDQKMIEELTSETAGQKSKVITKESKQSNVFYHAVFVQDAQGKQGYILVKSIIEPLKDVHQK
TWGLLIVGFVIACLVVIFLGMKITGQYIRPIESVTKVAIELAKGNYKARAYESHSDETGMLSKAINILARNLQEMTLEQE
MQQDRLHTLIENMGSGMILIDSRGYISLVNRSYKEIFHVTDEEYLDRLYYESFHHTEIIELVEEIFMTEVKVRKQVLLPL
DIERKHFEVYGAPIIGTNHEWKGIVLVFHDITELKKLEQMRKDFLANVSHELKTPITSIKGFSETLLDGAMKNQKFCEHF
LHIILKESERMQDLIEDLLDLSKIEQQGFKLNMGNVDIKDLLEDIKMVLDKKAQDKEIVLQMDAMQHVSVIGDSSRLKQI
FINLVHNAIIYTPVGGTVSVSLFEDEQNAYVQVADTGIGISKEEIPRIFERFYRVDKARSRNTGGTGLGLSIVKHLVEAH
HGMITVESKVGEGTMFTVALPKVNL
>Mature_585_residues
MNKFRSRLLFTFVSLIIFILVGLGVLLETLFENYYIEHTKERTVKETRYVALLVEELGIDKVLHAQNVFTELEEQIPISI
LFVDEAKKVQYSKSDKPVFDQKMIEELTSETAGQKSKVITKESKQSNVFYHAVFVQDAQGKQGYILVKSIIEPLKDVHQK
TWGLLIVGFVIACLVVIFLGMKITGQYIRPIESVTKVAIELAKGNYKARAYESHSDETGMLSKAINILARNLQEMTLEQE
MQQDRLHTLIENMGSGMILIDSRGYISLVNRSYKEIFHVTDEEYLDRLYYESFHHTEIIELVEEIFMTEVKVRKQVLLPL
DIERKHFEVYGAPIIGTNHEWKGIVLVFHDITELKKLEQMRKDFLANVSHELKTPITSIKGFSETLLDGAMKNQKFCEHF
LHIILKESERMQDLIEDLLDLSKIEQQGFKLNMGNVDIKDLLEDIKMVLDKKAQDKEIVLQMDAMQHVSVIGDSSRLKQI
FINLVHNAIIYTPVGGTVSVSLFEDEQNAYVQVADTGIGISKEEIPRIFERFYRVDKARSRNTGGTGLGLSIVKHLVEAH
HGMITVESKVGEGTMFTVALPKVNL

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=368, Percent_Identity=32.8804347826087, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=33.9130434782609, Blast_Score=148, Evalue=9e-37,
Organism=Escherichia coli, GI48994928, Length=328, Percent_Identity=30.1829268292683, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI1786783, Length=245, Percent_Identity=33.0612244897959, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1789149, Length=225, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI1788713, Length=227, Percent_Identity=32.15859030837, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI145693157, Length=229, Percent_Identity=32.3144104803493, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788549, Length=379, Percent_Identity=25.065963060686, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=30.8755760368664, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI87081816, Length=263, Percent_Identity=29.6577946768061, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1790861, Length=239, Percent_Identity=30.1255230125523, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1790346, Length=267, Percent_Identity=29.5880149812734, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082128, Length=231, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=25.974025974026, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788279, Length=233, Percent_Identity=27.0386266094421, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1787894, Length=263, Percent_Identity=26.2357414448669, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790551, Length=229, Percent_Identity=29.2576419213974, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789808, Length=235, Percent_Identity=28.5106382978723, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789403, Length=205, Percent_Identity=30.7317073170732, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790567, Length=347, Percent_Identity=25.6484149855908, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1790300, Length=238, Percent_Identity=25.6302521008403, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1787374, Length=246, Percent_Identity=25.2032520325203, Blast_Score=62, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=71, Percent_Identity=46.4788732394366, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66917; Mature: 66917

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFRSRLLFTFVSLIIFILVGLGVLLETLFENYYIEHTKERTVKETRYVALLVEELGID
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
KVLHAQNVFTELEEQIPISILFVDEAKKVQYSKSDKPVFDQKMIEELTSETAGQKSKVIT
HHHHHHHHHHHHHHHCCEEEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
KESKQSNVFYHAVFVQDAQGKQGYILVKSIIEPLKDVHQKTWGLLIVGFVIACLVVIFLG
CCCCCCCEEEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MKITGQYIRPIESVTKVAIELAKGNYKARAYESHSDETGMLSKAINILARNLQEMTLEQE
HHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MQQDRLHTLIENMGSGMILIDSRGYISLVNRSYKEIFHVTDEEYLDRLYYESFHHTEIIE
HHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHH
LVEEIFMTEVKVRKQVLLPLDIERKHFEVYGAPIIGTNHEWKGIVLVFHDITELKKLEQM
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEECCCCCCCEEEEEEHHHHHHHHHHHH
RKDFLANVSHELKTPITSIKGFSETLLDGAMKNQKFCEHFLHIILKESERMQDLIEDLLD
HHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSKIEQQGFKLNMGNVDIKDLLEDIKMVLDKKAQDKEIVLQMDAMQHVSVIGDSSRLKQI
HHHHHHCCCEEECCCCCHHHHHHHHHHHHCCCCCCCHHEEEHHHHHHHHHHCCHHHHHHH
FINLVHNAIIYTPVGGTVSVSLFEDEQNAYVQVADTGIGISKEEIPRIFERFYRVDKARS
HHHHHHCCEEEECCCCEEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCC
RNTGGTGLGLSIVKHLVEAHHGMITVESKVGEGTMFTVALPKVNL
CCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MNKFRSRLLFTFVSLIIFILVGLGVLLETLFENYYIEHTKERTVKETRYVALLVEELGID
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
KVLHAQNVFTELEEQIPISILFVDEAKKVQYSKSDKPVFDQKMIEELTSETAGQKSKVIT
HHHHHHHHHHHHHHHCCEEEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
KESKQSNVFYHAVFVQDAQGKQGYILVKSIIEPLKDVHQKTWGLLIVGFVIACLVVIFLG
CCCCCCCEEEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MKITGQYIRPIESVTKVAIELAKGNYKARAYESHSDETGMLSKAINILARNLQEMTLEQE
HHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MQQDRLHTLIENMGSGMILIDSRGYISLVNRSYKEIFHVTDEEYLDRLYYESFHHTEIIE
HHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHH
LVEEIFMTEVKVRKQVLLPLDIERKHFEVYGAPIIGTNHEWKGIVLVFHDITELKKLEQM
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEECCCCCCCEEEEEEHHHHHHHHHHHH
RKDFLANVSHELKTPITSIKGFSETLLDGAMKNQKFCEHFLHIILKESERMQDLIEDLLD
HHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSKIEQQGFKLNMGNVDIKDLLEDIKMVLDKKAQDKEIVLQMDAMQHVSVIGDSSRLKQI
HHHHHHCCCEEECCCCCHHHHHHHHHHHHCCCCCCCHHEEEHHHHHHHHHHCCHHHHHHH
FINLVHNAIIYTPVGGTVSVSLFEDEQNAYVQVADTGIGISKEEIPRIFERFYRVDKARS
HHHHHHCCEEEECCCCEEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCC
RNTGGTGLGLSIVKHLVEAHHGMITVESKVGEGTMFTVALPKVNL
CCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]