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The map label for this gene is era [H]

Identifier: 152976731

GI number: 152976731

Start: 3073564

End: 3074469

Strand: Reverse

Name: era [H]

Synonym: Bcer98_3026

Alternate gene names: 152976731

Gene position: 3074469-3073564 (Counterclockwise)

Preceding gene: 152976732

Following gene: 152976730

Centisome position: 75.23

GC content: 35.32

Gene sequence:

>906_bases
ATGAATAACAAAGGTTATAAGTCAGGTTTTGTCTCTATTATAGGGAGACCAAATGTTGGAAAATCTACATTTTTAAATCG
AATTATCGGTCAAAAAATTGCTATTATGAGTGATAAGCCACAAACAACTCGTAATAAAGTACAAGGTGTATATACAGAAA
ATGATGCGCAAGTGATTTTTATCGATACGCCTGGAATACATAAGCCAAAACATAAATTAGGCGATTTTATGGTGAAAATG
GCGCAAACGACATTGAAAGAAGTTGATATTGTACTCTTTATGGTCAATGCGGCGGAAGGCTTTGGTCGTGGTGAAGAATA
CATTATTGAAAAATTGAAGGAAACGAGGCAACCAGTATTTTTAGTAATTAATAAAATCGATCAAGTTCATCCAGAAAAAT
TATTAGAATTGATTGATCAATATCGTAACTTGTACGAGTTTGCAGAAATTGTGCCGATTTCTGCTTTGGAAGGTAATAAT
GTGGAAGCGTTAATTGGGGCGATTAAAAAATACTTACCAGAAGGGCCACAGTACTATCCAGAAAATCAAGTAACAGATCA
TCCGGAACGATTTATTATTGCTGAATTAATCCGTGAGAAAGTGCTTCATTTAACACGTGAGGAAGTACCTCATTCAGTAG
CAGTTGCGATTGATGCGATTCAAAAGCGTGAAGGTGGAGCGGTTTATGTAAATGCAACAATCATCGTGGAACGTCCTTCT
CAAAAAGGAATTATTATTGGAAAGCAAGGAAAAATGTTGAAAGAAATTGGGAAGCGAGCTCGTTTTGATATTGAAGCCCT
TCTTGGTTCTAAAGTGTTTTTAGAAGTATGGGTAAAAGTACAAAAAGATTGGCGTAATAAAATGTCCCAACTTCGTGATT
TAGGTTTCCGTGAAGATGAATATTAA

Upstream 100 bases:

>100_bases
TAAACAGAACATAAAATATATTTATCAAATTTACATGGTGACACTGGGAAGACGACAGTTAGAAAGTTGTTGCCAGTAGC
ATTTTTAGCGGAGGATTTAC

Downstream 100 bases:

>100_bases
TAGAAATTAGGAAAATTTTTTCTCACATGAAAATGGACAAAATGGGTCATTTTAATAACAACAAAAGAAATTGGTTTACA
TGCTATGCTTACTTAGAAAG

Product: GTP-binding protein Era

Products: NA

Alternate protein names: Bex protein [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MNNKGYKSGFVSIIGRPNVGKSTFLNRIIGQKIAIMSDKPQTTRNKVQGVYTENDAQVIFIDTPGIHKPKHKLGDFMVKM
AQTTLKEVDIVLFMVNAAEGFGRGEEYIIEKLKETRQPVFLVINKIDQVHPEKLLELIDQYRNLYEFAEIVPISALEGNN
VEALIGAIKKYLPEGPQYYPENQVTDHPERFIIAELIREKVLHLTREEVPHSVAVAIDAIQKREGGAVYVNATIIVERPS
QKGIIIGKQGKMLKEIGKRARFDIEALLGSKVFLEVWVKVQKDWRNKMSQLRDLGFREDEY

Sequences:

>Translated_301_residues
MNNKGYKSGFVSIIGRPNVGKSTFLNRIIGQKIAIMSDKPQTTRNKVQGVYTENDAQVIFIDTPGIHKPKHKLGDFMVKM
AQTTLKEVDIVLFMVNAAEGFGRGEEYIIEKLKETRQPVFLVINKIDQVHPEKLLELIDQYRNLYEFAEIVPISALEGNN
VEALIGAIKKYLPEGPQYYPENQVTDHPERFIIAELIREKVLHLTREEVPHSVAVAIDAIQKREGGAVYVNATIIVERPS
QKGIIIGKQGKMLKEIGKRARFDIEALLGSKVFLEVWVKVQKDWRNKMSQLRDLGFREDEY
>Mature_301_residues
MNNKGYKSGFVSIIGRPNVGKSTFLNRIIGQKIAIMSDKPQTTRNKVQGVYTENDAQVIFIDTPGIHKPKHKLGDFMVKM
AQTTLKEVDIVLFMVNAAEGFGRGEEYIIEKLKETRQPVFLVINKIDQVHPEKLLELIDQYRNLYEFAEIVPISALEGNN
VEALIGAIKKYLPEGPQYYPENQVTDHPERFIIAELIREKVLHLTREEVPHSVAVAIDAIQKREGGAVYVNATIIVERPS
QKGIIIGKQGKMLKEIGKRARFDIEALLGSKVFLEVWVKVQKDWRNKMSQLRDLGFREDEY

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. Binds both GDP and GTP. Complements

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=322, Percent_Identity=26.3975155279503, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI1788919, Length=299, Percent_Identity=40.133779264214, Blast_Score=237, Evalue=9e-64,
Organism=Escherichia coli, GI87082120, Length=179, Percent_Identity=33.5195530726257, Blast_Score=96, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323665, Length=196, Percent_Identity=25, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646434, Length=306, Percent_Identity=25.1633986928105, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34316; Mature: 34316

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKGYKSGFVSIIGRPNVGKSTFLNRIIGQKIAIMSDKPQTTRNKVQGVYTENDAQVIF
CCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCEEEECCCCCHHHHHHCCEEECCCCEEEE
IDTPGIHKPKHKLGDFMVKMAQTTLKEVDIVLFMVNAAEGFGRGEEYIIEKLKETRQPVF
EECCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHCCCEE
LVINKIDQVHPEKLLELIDQYRNLYEFAEIVPISALEGNNVEALIGAIKKYLPEGPQYYP
EEEHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
ENQVTDHPERFIIAELIREKVLHLTREEVPHSVAVAIDAIQKREGGAVYVNATIIVERPS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEEEEECCC
QKGIIIGKQGKMLKEIGKRARFDIEALLGSKVFLEVWVKVQKDWRNKMSQLRDLGFREDE
CCCEEECCCCHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
Y
C
>Mature Secondary Structure
MNNKGYKSGFVSIIGRPNVGKSTFLNRIIGQKIAIMSDKPQTTRNKVQGVYTENDAQVIF
CCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCEEEECCCCCHHHHHHCCEEECCCCEEEE
IDTPGIHKPKHKLGDFMVKMAQTTLKEVDIVLFMVNAAEGFGRGEEYIIEKLKETRQPVF
EECCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHCCCEE
LVINKIDQVHPEKLLELIDQYRNLYEFAEIVPISALEGNNVEALIGAIKKYLPEGPQYYP
EEEHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
ENQVTDHPERFIIAELIREKVLHLTREEVPHSVAVAIDAIQKREGGAVYVNATIIVERPS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEEEEECCC
QKGIIIGKQGKMLKEIGKRARFDIEALLGSKVFLEVWVKVQKDWRNKMSQLRDLGFREDE
CCCEEECCCCHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
Y
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 2526291 [H]