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The map label for this gene is xseA

Identifier: 152976584

GI number: 152976584

Start: 2947353

End: 2948708

Strand: Reverse

Name: xseA

Synonym: Bcer98_2873

Alternate gene names: 152976584

Gene position: 2948708-2947353 (Counterclockwise)

Preceding gene: 152976585

Following gene: 152976583

Centisome position: 72.15

GC content: 37.32

Gene sequence:

>1356_bases
ATGGAAAAGCAATATTTAACCGTTACAGCATTAACACGTTATATCAAAACAAAAATAGAGTATGATCCGCATTTGCAGTC
TGTTTGGTTAAAAGGAGAAATTTCAAACTTTAAATATCATAGCCGTGGCCATATGTATTTTACATTGAAAGATGAAAATG
CAAGGATTGCAGCGGTTATGTTTGCGGGGCATAATCGTAATATAAAATTCAGACCAGAAGATGGAATGAAAGTGCTTGTA
AAAGGGAAAATCTCTGTCTATGAAGCAAGTGGTTCTTATCAAATTTATGTTCATGATATGCAACCTGATGGTGTGGGGAA
TCTTCACTTAGCTTATGAACAATTAAAGGTTCGACTAGAGGAAGAAGGATTATTTTCTCGCGTTTATAAGCAACCCATTC
CTGCATATGCAAAAACAATAGGTGTGATTACATCACCAACGGGGGCGGCTATTCGTGATATTATAACGACGATTAAACGT
CGCTATCCAATTGGGAATGTGATTGTTTTTCCAGTACTTGTACAAGGGGAGTTTGCTGCTCCCTCTATTGTACAAGCTAT
TCAAACAGCAAATGAGATGAATGATATAGATGTATTAATTGTTGGTCGCGGGGGCGGTTCTATTGAGGAGCTATGGGCTT
TTAATGAAGAAATAGTCGCGCGAGCAATTTTTGCAAGTAAGATTCCCATTATCTCTGCTGTTGGACATGAAACTGATTTT
ACAATCGCTGATTTTGTTGCAGATTTACGTGCACCGACGCCGACAGCAGCTGCTGAATTAGCTGTGCCTAATATTCTTGA
AATGCAAGAGAAAGTATTGCAAAGAACACTTCGTTTACAAAGAGCGATGCGAGAAATAGTACATAAAAGGCAAGAGCGAT
TACAAACGTTGCAAAAGTCATATGCATTTCGTTATCCAAGACAAATATATGAACAAAAAGAAGAGCAGTTAGATCGAGCT
CTTGAGCAACTTGTTTTAGCAAAAGAGCGCTATATGGAGAAAAAAGTGAATCAGTTAAAGCAGCTCTCATTTTACTTGGA
GAAGCACCATCCTGCTCAAAGAATTTCACAAACAAAGATAGCGATTGAAACGTTGCAAAAACAATTACGACGAGAAATGC
AAACGGTGTTACAAACGAAAGAATTTGCATTTGTGAGAATAGCAAAGCAACTAGAAGCATTAAGTCCGCTTAAAGTTATG
ATGAGAGGATATGGACTTGTATATAGCGAGAAGAATCAAGTATTGAAAAGTGTAAAAGATGTTAGTGCTGGAGATGTAGT
TTCCGTGCAATTACAAGATGGTATATTAGATTGTAATGTATCGAGCGTAAAGGAGCGTGAATCAAATGGAAAATAA

Upstream 100 bases:

>100_bases
GTCCGATGACAATTACAATGCTTCTTCATAATACAGTTGAATCTGCTAAACGTGCAGGTTTTATCTGTAAATAATTTGAA
GCGGCTATGAGGAGAGAGAA

Downstream 100 bases:

>100_bases
ATTGAGCTTTGAAGAGGCGATTTCACAGCTTGAGCATCTCGTTTCCAAGCTTGAACAAGGCGATGTTCCTTTAGAAGAAG
CAATTTCATACTTTAAAGAA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKYHSRGHMYFTLKDENARIAAVMFAGHNRNIKFRPEDGMKVLV
KGKISVYEASGSYQIYVHDMQPDGVGNLHLAYEQLKVRLEEEGLFSRVYKQPIPAYAKTIGVITSPTGAAIRDIITTIKR
RYPIGNVIVFPVLVQGEFAAPSIVQAIQTANEMNDIDVLIVGRGGGSIEELWAFNEEIVARAIFASKIPIISAVGHETDF
TIADFVADLRAPTPTAAAELAVPNILEMQEKVLQRTLRLQRAMREIVHKRQERLQTLQKSYAFRYPRQIYEQKEEQLDRA
LEQLVLAKERYMEKKVNQLKQLSFYLEKHHPAQRISQTKIAIETLQKQLRREMQTVLQTKEFAFVRIAKQLEALSPLKVM
MRGYGLVYSEKNQVLKSVKDVSAGDVVSVQLQDGILDCNVSSVKERESNGK

Sequences:

>Translated_451_residues
MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKYHSRGHMYFTLKDENARIAAVMFAGHNRNIKFRPEDGMKVLV
KGKISVYEASGSYQIYVHDMQPDGVGNLHLAYEQLKVRLEEEGLFSRVYKQPIPAYAKTIGVITSPTGAAIRDIITTIKR
RYPIGNVIVFPVLVQGEFAAPSIVQAIQTANEMNDIDVLIVGRGGGSIEELWAFNEEIVARAIFASKIPIISAVGHETDF
TIADFVADLRAPTPTAAAELAVPNILEMQEKVLQRTLRLQRAMREIVHKRQERLQTLQKSYAFRYPRQIYEQKEEQLDRA
LEQLVLAKERYMEKKVNQLKQLSFYLEKHHPAQRISQTKIAIETLQKQLRREMQTVLQTKEFAFVRIAKQLEALSPLKVM
MRGYGLVYSEKNQVLKSVKDVSAGDVVSVQLQDGILDCNVSSVKERESNGK
>Mature_451_residues
MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKYHSRGHMYFTLKDENARIAAVMFAGHNRNIKFRPEDGMKVLV
KGKISVYEASGSYQIYVHDMQPDGVGNLHLAYEQLKVRLEEEGLFSRVYKQPIPAYAKTIGVITSPTGAAIRDIITTIKR
RYPIGNVIVFPVLVQGEFAAPSIVQAIQTANEMNDIDVLIVGRGGGSIEELWAFNEEIVARAIFASKIPIISAVGHETDF
TIADFVADLRAPTPTAAAELAVPNILEMQEKVLQRTLRLQRAMREIVHKRQERLQTLQKSYAFRYPRQIYEQKEEQLDRA
LEQLVLAKERYMEKKVNQLKQLSFYLEKHHPAQRISQTKIAIETLQKQLRREMQTVLQTKEFAFVRIAKQLEALSPLKVM
MRGYGLVYSEKNQVLKSVKDVSAGDVVSVQLQDGILDCNVSSVKERESNGK

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=439, Percent_Identity=42.5968109339408, Blast_Score=362, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_BACCN (A7GSJ8)

Other databases:

- EMBL:   CP000764
- RefSeq:   YP_001376101.1
- STRING:   A7GSJ8
- EnsemblBacteria:   EBBACT00000037032
- GeneID:   5347282
- GenomeReviews:   CP000764_GR
- KEGG:   bcy:Bcer98_2873
- eggNOG:   COG1570
- GeneTree:   EBGT00050000001906
- HOGENOM:   HBG634411
- OMA:   ANERREC
- ProtClustDB:   PRK00286
- BioCyc:   BCER315749:BCER98_2873-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 51457; Mature: 51457

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKYHSRGHMYFTLKDENARIAAVM
CCCCEEHHHHHHHHHHHHCCCCCCHHHEEEEEECCCCEEECCCEEEEEEECCCCEEEEEE
FAGHNRNIKFRPEDGMKVLVKGKISVYEASGSYQIYVHDMQPDGVGNLHLAYEQLKVRLE
EECCCCCEEECCCCCCEEEEECCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHH
EEGLFSRVYKQPIPAYAKTIGVITSPTGAAIRDIITTIKRRYPIGNVIVFPVLVQGEFAA
HHHHHHHHHHCCCCHHHHHHCCEECCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCC
PSIVQAIQTANEMNDIDVLIVGRGGGSIEELWAFNEEIVARAIFASKIPIISAVGHETDF
HHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCC
TIADFVADLRAPTPTAAAELAVPNILEMQEKVLQRTLRLQRAMREIVHKRQERLQTLQKS
HHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAFRYPRQIYEQKEEQLDRALEQLVLAKERYMEKKVNQLKQLSFYLEKHHPAQRISQTKI
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AIETLQKQLRREMQTVLQTKEFAFVRIAKQLEALSPLKVMMRGYGLVYSEKNQVLKSVKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHC
VSAGDVVSVQLQDGILDCNVSSVKERESNGK
CCCCCEEEEEEECCEEECCHHHHHHHCCCCC
>Mature Secondary Structure
MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKYHSRGHMYFTLKDENARIAAVM
CCCCEEHHHHHHHHHHHHCCCCCCHHHEEEEEECCCCEEECCCEEEEEEECCCCEEEEEE
FAGHNRNIKFRPEDGMKVLVKGKISVYEASGSYQIYVHDMQPDGVGNLHLAYEQLKVRLE
EECCCCCEEECCCCCCEEEEECCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHH
EEGLFSRVYKQPIPAYAKTIGVITSPTGAAIRDIITTIKRRYPIGNVIVFPVLVQGEFAA
HHHHHHHHHHCCCCHHHHHHCCEECCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCC
PSIVQAIQTANEMNDIDVLIVGRGGGSIEELWAFNEEIVARAIFASKIPIISAVGHETDF
HHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCC
TIADFVADLRAPTPTAAAELAVPNILEMQEKVLQRTLRLQRAMREIVHKRQERLQTLQKS
HHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAFRYPRQIYEQKEEQLDRALEQLVLAKERYMEKKVNQLKQLSFYLEKHHPAQRISQTKI
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AIETLQKQLRREMQTVLQTKEFAFVRIAKQLEALSPLKVMMRGYGLVYSEKNQVLKSVKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHC
VSAGDVVSVQLQDGILDCNVSSVKERESNGK
CCCCCEEEEEEECCEEECCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA