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The map label for this gene is pyrD [H]

Identifier: 152976245

GI number: 152976245

Start: 2631888

End: 2632817

Strand: Reverse

Name: pyrD [H]

Synonym: Bcer98_2533

Alternate gene names: 152976245

Gene position: 2632817-2631888 (Counterclockwise)

Preceding gene: 152976246

Following gene: 152976244

Centisome position: 64.42

GC content: 40.32

Gene sequence:

>930_bases
ATGAACAGATTACAAGTTGAATTACCAGGATTATCATTAAAAAATCCAATCATCCCAGCATCTGGTTGCTTCGGATTTGG
TCGTGAATATGCTCAGTTTTATGATTTAAATGTACTGGGCTCAATCATGATTAAAGCAACGACGGAACAACCACGATATG
GAAATCCGACGCCACGTGTGGCGGAAACACCAGGTGGTATGTTAAATGCAATCGGGCTTCAAAATCCAGGGCTAGAAAAG
GTAATGGGCTCTGAATTACCATGGTTAGAACAATTTGATCTTCCAATTATAGCGAATGTTGCAGGTTCACAAGTTGAAGA
CTATGTAGCAGTAGCAAAGAAAATTTCAAAAGCACCGAATGTTCATGCACTAGAATTAAATATTTCTTGTCCCAATGTAA
AAACGGGAGGTATCGCTTTTGGTACAAATCCTGAAATTGCTGCTGATTTAACGAAGCGAGTAAAAGAGGTTTCTGAAGTG
CCGGTATATGTGAAATTGTCACCGAACGTGACAAACATTGTCGAGATTGCGAAGGCAATTGAAAATGCAGGTGCGGACGG
GTTAACGATGATTAATACATTGCTTGGTATGCGTCTAGATTTAAAAACAGCAAAACCAATTTTAGCAAACCGTACAGGCG
GACTATCAGGTCCTGCAATTAAACCGGTAGCAATTCGCATGGTACATGAAGTAAGCCAAGTGGTTGATATTCCAATTATT
GGAATGGGTGGTATTGAGTCAGCAGAAGATGTTATTGAATTCTTCTATGCTGGTGCAAGTGCAGTTGCGGTTGGTACAGC
AAACTTTGTTGATCCGCTCGTATGCCCAACCATTATTGAGGAATTACCATCGTTATTAGATGAATTAGGATTTGGACACA
TTTCGGAATGTCAAGGAAGGAGCTGGAAACAAGTATGTCAAAGTCGCTAA

Upstream 100 bases:

>100_bases
GTTTCGCGTGCGTATGTCACTTACAAGAAGATCCAAGCGGACATTCTTATAAAAAAGTGTGCAGCGATGGACCTGTGTTT
CCAATCGGGGAGGTTGTACT

Downstream 100 bases:

>100_bases
TTGTTGCACTAGATTTTCCAGGGAAAAAAGAGGTAGAACAATTTTTACAACACTTTGAAGGGGAAGAGTTATTTGTCAAA
GTGGGTATGGAATTGTTTTA

Product: dihydroorotate dehydrogenase 1B

Products: NA

Alternate protein names: DHOdehase; DHOD; DHODase; Dihydroorotate oxidase [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MNRLQVELPGLSLKNPIIPASGCFGFGREYAQFYDLNVLGSIMIKATTEQPRYGNPTPRVAETPGGMLNAIGLQNPGLEK
VMGSELPWLEQFDLPIIANVAGSQVEDYVAVAKKISKAPNVHALELNISCPNVKTGGIAFGTNPEIAADLTKRVKEVSEV
PVYVKLSPNVTNIVEIAKAIENAGADGLTMINTLLGMRLDLKTAKPILANRTGGLSGPAIKPVAIRMVHEVSQVVDIPII
GMGGIESAEDVIEFFYAGASAVAVGTANFVDPLVCPTIIEELPSLLDELGFGHISECQGRSWKQVCQSR

Sequences:

>Translated_309_residues
MNRLQVELPGLSLKNPIIPASGCFGFGREYAQFYDLNVLGSIMIKATTEQPRYGNPTPRVAETPGGMLNAIGLQNPGLEK
VMGSELPWLEQFDLPIIANVAGSQVEDYVAVAKKISKAPNVHALELNISCPNVKTGGIAFGTNPEIAADLTKRVKEVSEV
PVYVKLSPNVTNIVEIAKAIENAGADGLTMINTLLGMRLDLKTAKPILANRTGGLSGPAIKPVAIRMVHEVSQVVDIPII
GMGGIESAEDVIEFFYAGASAVAVGTANFVDPLVCPTIIEELPSLLDELGFGHISECQGRSWKQVCQSR
>Mature_309_residues
MNRLQVELPGLSLKNPIIPASGCFGFGREYAQFYDLNVLGSIMIKATTEQPRYGNPTPRVAETPGGMLNAIGLQNPGLEK
VMGSELPWLEQFDLPIIANVAGSQVEDYVAVAKKISKAPNVHALELNISCPNVKTGGIAFGTNPEIAADLTKRVKEVSEV
PVYVKLSPNVTNIVEIAKAIENAGADGLTMINTLLGMRLDLKTAKPILANRTGGLSGPAIKPVAIRMVHEVSQVVDIPII
GMGGIESAEDVIEFFYAGASAVAVGTANFVDPLVCPTIIEELPSLLDELGFGHISECQGRSWKQVCQSR

Specific function: Unknown

COG id: COG0167

COG function: function code F; Dihydroorotate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=309, Percent_Identity=31.0679611650485, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI45006951, Length=326, Percent_Identity=29.4478527607362, Blast_Score=108, Evalue=6e-24,
Organism=Escherichia coli, GI87082059, Length=283, Percent_Identity=29.3286219081272, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1787177, Length=277, Percent_Identity=27.7978339350181, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71984108, Length=172, Percent_Identity=38.953488372093, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17509475, Length=327, Percent_Identity=27.5229357798165, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6322633, Length=305, Percent_Identity=27.5409836065574, Blast_Score=92, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24640763, Length=200, Percent_Identity=35.5, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI18858217, Length=200, Percent_Identity=35.5, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI281361352, Length=325, Percent_Identity=29.8461538461538, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17137316, Length=325, Percent_Identity=29.8461538461538, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005720
- InterPro:   IPR012135
- InterPro:   IPR001295 [H]

Pfam domain/function: PF01180 DHO_dh [H]

EC number: =1.3.3.1 [H]

Molecular weight: Translated: 32932; Mature: 32932

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00911 DHODEHASE_1 ; PS00912 DHODEHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLQVELPGLSLKNPIIPASGCFGFGREYAQFYDLNVLGSIMIKATTEQPRYGNPTPRV
CCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCC
AETPGGMLNAIGLQNPGLEKVMGSELPWLEQFDLPIIANVAGSQVEDYVAVAKKISKAPN
CCCCCCCEEECCCCCCCHHHHHCCCCCCHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCC
VHALELNISCPNVKTGGIAFGTNPEIAADLTKRVKEVSEVPVYVKLSPNVTNIVEIAKAI
EEEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHH
ENAGADGLTMINTLLGMRLDLKTAKPILANRTGGLSGPAIKPVAIRMVHEVSQVVDIPII
HHCCCCHHHHHHHHHCCEECCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
GMGGIESAEDVIEFFYAGASAVAVGTANFVDPLVCPTIIEELPSLLDELGFGHISECQGR
CCCCCCHHHHHHHHHHCCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC
SWKQVCQSR
CHHHHHCCC
>Mature Secondary Structure
MNRLQVELPGLSLKNPIIPASGCFGFGREYAQFYDLNVLGSIMIKATTEQPRYGNPTPRV
CCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCC
AETPGGMLNAIGLQNPGLEKVMGSELPWLEQFDLPIIANVAGSQVEDYVAVAKKISKAPN
CCCCCCCEEECCCCCCCHHHHHCCCCCCHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCC
VHALELNISCPNVKTGGIAFGTNPEIAADLTKRVKEVSEVPVYVKLSPNVTNIVEIAKAI
EEEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHH
ENAGADGLTMINTLLGMRLDLKTAKPILANRTGGLSGPAIKPVAIRMVHEVSQVVDIPII
HHCCCCHHHHHHHHHCCEECCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
GMGGIESAEDVIEFFYAGASAVAVGTANFVDPLVCPTIIEELPSLLDELGFGHISECQGR
CCCCCCHHHHHHHHHHCCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC
SWKQVCQSR
CHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA