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The map label for this gene is fmt [H]

Identifier: 152976232

GI number: 152976232

Start: 2617411

End: 2618355

Strand: Reverse

Name: fmt [H]

Synonym: Bcer98_2518

Alternate gene names: 152976232

Gene position: 2618355-2617411 (Counterclockwise)

Preceding gene: 152976233

Following gene: 152976231

Centisome position: 64.07

GC content: 39.47

Gene sequence:

>945_bases
ATGATAAAAGTAGTATTTATGGGGACACCGGACTTTTCTGTACCGGTGCTTCGTCGTCTTATTGAGGATGGATATGATGT
AGTTGGTGTTGTAACACAGCCAGATCGTCCAGTGGGCAGAAAAAAAGTAATGACGCCAACGCCTGTTAAGGTTGAAGCGG
AAAAGCACGGTATCCCAGTGTTACAACCTTTAAAAATTCGCGAACAAGATGAATATGAGAAAGTATTGGCGCTAGAGCCT
GATTTAATCGTAACAGCTGCGTTCGGGCAAATTATACCAAAGGAAATTTTAGAAGCACCGAAATATGGCTGTATTAATGT
ACATGCATCATTACTTCCAGAGCTTCGCGGTGGTGCACCAATTCATTATGCCATTATGCAGGGAAAAGAAAAAACAGGTA
TTACGATTATGTACATGGTTGAAAAATTAGATGCTGGTGATATTTTAACGCAAGTAGAAGTGGAAATTGAAGAACGTGAA
ACAACAGGGTCATTGTTCGATAAATTGAGTGAAGCTGGAGCACACTTATTATCTAAAACAGTGCCGCTTTTAGTTCAAGG
TAAATTAGAACCAATTAAACAGGACGAGGAAAAAGTTACATTTGCCTATAATATTAAGCGGGAACAAGAAAAAATTAATT
GGGCGAAAACAGGTGAAGAGGTATACAATCACATTCGTGGATTAAATCCATGGCCGGTTGCATATACAACTTTAGCTGGA
CAAGTAGTAAAAGTATGGTGGGGAGAAAAAGTTCCTACAGCGAATGATGCCCAGCCGGGAACAATTGTAGAGATTCAAGA
GGATGGTTTTATTGTAGTTACTGGAAATGAAACAGGTATTAAGATTACCGAGTTACAGCCAGCTGGTAAAAAACGTATGA
GTTCTTCACAATTTTTACGCGGGGCAAAACTGGAGATTGGTATGAAGTTAGGAGAAGATGCATGA

Upstream 100 bases:

>100_bases
CATGAAATCGATCATTTACATGGTGTATTATTTACATCAAAAGTAACGAGATATTATGAGGAAAATGAATTAGAAGAGAA
ATAAAAGGAGCGGTCTTTGC

Downstream 100 bases:

>100_bases
GACAAAACGTTCGTGAGTTAGCTCTTGATGGATTAATGCAAGTAGAAAAAAGCGGTGCTTACAGTAACTTGCTATTAAAT
CATTTGATTGAAAAAAGTAC

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MIKVVFMGTPDFSVPVLRRLIEDGYDVVGVVTQPDRPVGRKKVMTPTPVKVEAEKHGIPVLQPLKIREQDEYEKVLALEP
DLIVTAAFGQIIPKEILEAPKYGCINVHASLLPELRGGAPIHYAIMQGKEKTGITIMYMVEKLDAGDILTQVEVEIEERE
TTGSLFDKLSEAGAHLLSKTVPLLVQGKLEPIKQDEEKVTFAYNIKREQEKINWAKTGEEVYNHIRGLNPWPVAYTTLAG
QVVKVWWGEKVPTANDAQPGTIVEIQEDGFIVVTGNETGIKITELQPAGKKRMSSSQFLRGAKLEIGMKLGEDA

Sequences:

>Translated_314_residues
MIKVVFMGTPDFSVPVLRRLIEDGYDVVGVVTQPDRPVGRKKVMTPTPVKVEAEKHGIPVLQPLKIREQDEYEKVLALEP
DLIVTAAFGQIIPKEILEAPKYGCINVHASLLPELRGGAPIHYAIMQGKEKTGITIMYMVEKLDAGDILTQVEVEIEERE
TTGSLFDKLSEAGAHLLSKTVPLLVQGKLEPIKQDEEKVTFAYNIKREQEKINWAKTGEEVYNHIRGLNPWPVAYTTLAG
QVVKVWWGEKVPTANDAQPGTIVEIQEDGFIVVTGNETGIKITELQPAGKKRMSSSQFLRGAKLEIGMKLGEDA
>Mature_314_residues
MIKVVFMGTPDFSVPVLRRLIEDGYDVVGVVTQPDRPVGRKKVMTPTPVKVEAEKHGIPVLQPLKIREQDEYEKVLALEP
DLIVTAAFGQIIPKEILEAPKYGCINVHASLLPELRGGAPIHYAIMQGKEKTGITIMYMVEKLDAGDILTQVEVEIEERE
TTGSLFDKLSEAGAHLLSKTVPLLVQGKLEPIKQDEEKVTFAYNIKREQEKINWAKTGEEVYNHIRGLNPWPVAYTTLAG
QVVKVWWGEKVPTANDAQPGTIVEIQEDGFIVVTGNETGIKITELQPAGKKRMSSSQFLRGAKLEIGMKLGEDA

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=318, Percent_Identity=30.5031446540881, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI238814322, Length=313, Percent_Identity=29.073482428115, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI164663775, Length=236, Percent_Identity=30.9322033898305, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI1789683, Length=302, Percent_Identity=43.7086092715232, Blast_Score=272, Evalue=2e-74,
Organism=Escherichia coli, GI1788589, Length=312, Percent_Identity=27.8846153846154, Blast_Score=147, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI133930964, Length=327, Percent_Identity=31.4984709480122, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6319458, Length=278, Percent_Identity=26.6187050359712, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45550868, Length=306, Percent_Identity=33.6601307189542, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28571984, Length=283, Percent_Identity=33.2155477031802, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24585660, Length=245, Percent_Identity=26.9387755102041, Blast_Score=91, Evalue=9e-19,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 34804; Mature: 34804

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVVFMGTPDFSVPVLRRLIEDGYDVVGVVTQPDRPVGRKKVMTPTPVKVEAEKHGIPV
CEEEEEECCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCEEEEHHHCCCCC
LQPLKIREQDEYEKVLALEPDLIVTAAFGQIIPKEILEAPKYGCINVHASLLPELRGGAP
CCCCCCCCCCCHHHEEEECCCEEEEEHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCC
IHYAIMQGKEKTGITIMYMVEKLDAGDILTQVEVEIEERETTGSLFDKLSEAGAHLLSKT
EEEEEECCCCCCCEEEEEEEECCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHC
VPLLVQGKLEPIKQDEEKVTFAYNIKREQEKINWAKTGEEVYNHIRGLNPWPVAYTTLAG
CCEEEECCCCCCCCCCCEEEEEEEEEHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHC
QVVKVWWGEKVPTANDAQPGTIVEIQEDGFIVVTGNETGIKITELQPAGKKRMSSSQFLR
EEEEEECCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCEEEEEECCCCHHHCCHHHHHC
GAKLEIGMKLGEDA
CCEEEEEEECCCCC
>Mature Secondary Structure
MIKVVFMGTPDFSVPVLRRLIEDGYDVVGVVTQPDRPVGRKKVMTPTPVKVEAEKHGIPV
CEEEEEECCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCEEEEHHHCCCCC
LQPLKIREQDEYEKVLALEPDLIVTAAFGQIIPKEILEAPKYGCINVHASLLPELRGGAP
CCCCCCCCCCCHHHEEEECCCEEEEEHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCC
IHYAIMQGKEKTGITIMYMVEKLDAGDILTQVEVEIEERETTGSLFDKLSEAGAHLLSKT
EEEEEECCCCCCCEEEEEEEECCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHC
VPLLVQGKLEPIKQDEEKVTFAYNIKREQEKINWAKTGEEVYNHIRGLNPWPVAYTTLAG
CCEEEECCCCCCCCCCCEEEEEEEEEHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHC
QVVKVWWGEKVPTANDAQPGTIVEIQEDGFIVVTGNETGIKITELQPAGKKRMSSSQFLR
EEEEEECCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCEEEEEECCCCHHHCCHHHHHC
GAKLEIGMKLGEDA
CCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA