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The map label for this gene is pyrH [H]

Identifier: 152976191

GI number: 152976191

Start: 2575116

End: 2575838

Strand: Reverse

Name: pyrH [H]

Synonym: Bcer98_2477

Alternate gene names: 152976191

Gene position: 2575838-2575116 (Counterclockwise)

Preceding gene: 152976192

Following gene: 152976190

Centisome position: 63.02

GC content: 39.0

Gene sequence:

>723_bases
ATGACTAAACCGAAATATAATCGTGTAGTATTAAAGTTAAGCGGTGAAGCTTTAGCTGGTGAAAAAGGCTTTGGAATTAA
CCCAGCTGTTATTAAGTCAGTTGCGGAGCAAGTAAAAGAAATTGCAGAACTTGATGTTGAAGTTGCTGTTGTTGTTGGTG
GCGGTAACATTTGGCGTGGGAAAATCGGAAGTGAAATGGGCATGGACCGCGCAGGCGCAGATTATATGGGCATGTTAGCG
ACAGTAATGAATTCATTAGCTCTTCAAGACAGTTTAGAGAACATGGGCATTCAAACGCGTGTTCAAACGTCAATTGAAAT
GCGTCAAGTAGCAGAGCCTTACATTCGTCGTAAAGCAGTTCGTCATTTAGAGAAAAAACGCGTTGTTATTTTCGCAGCCG
GTACAGGTAACCCATACTTCTCTACAGATACGACTGCAGCATTACGCGCAGCAGAAATTGAAGCGGATGTTATTTTAATG
GCAAAAAATAATGTGGATGGCGTATATAACGCAGATCCATCTGTTGATCCAACAGCTACAAAATATGAATCACTTACATA
CTTAGACGTATTAAAAGAAGGTTTAGGTGTAATGGATTCTACAGCTTCTTCATTATGTATGGATAACGATATTCCATTAA
TTGTATTCTCGATTATGGAAAAAGGAAATATTAAACGTGCTGTTTTAGGCGAAAATATCGGAACAATTGTAAGGGGGAAA
TAA

Upstream 100 bases:

>100_bases
AGAAGTAATGAACCAAGTAAAAGGTAACAACTAATACAGATTAGGGAACACATTGTGTTCCCTTTTTTAAAATAAAGATG
TAAGTAATTGGAGGTTCATT

Downstream 100 bases:

>100_bases
CTATGGGACAACAAGTAATTAAATCGTCAACTGAAAAAATGGAAAAAGCAGTTGCTGCTTATTCTCGTGAATTAGCAACA
GTTCGTGCTGGTCGTGCTAG

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTKPKYNRVVLKLSGEALAGEKGFGINPAVIKSVAEQVKEIAELDVEVAVVVGGGNIWRGKIGSEMGMDRAGADYMGMLA
TVMNSLALQDSLENMGIQTRVQTSIEMRQVAEPYIRRKAVRHLEKKRVVIFAAGTGNPYFSTDTTAALRAAEIEADVILM
AKNNVDGVYNADPSVDPTATKYESLTYLDVLKEGLGVMDSTASSLCMDNDIPLIVFSIMEKGNIKRAVLGENIGTIVRGK

Sequences:

>Translated_240_residues
MTKPKYNRVVLKLSGEALAGEKGFGINPAVIKSVAEQVKEIAELDVEVAVVVGGGNIWRGKIGSEMGMDRAGADYMGMLA
TVMNSLALQDSLENMGIQTRVQTSIEMRQVAEPYIRRKAVRHLEKKRVVIFAAGTGNPYFSTDTTAALRAAEIEADVILM
AKNNVDGVYNADPSVDPTATKYESLTYLDVLKEGLGVMDSTASSLCMDNDIPLIVFSIMEKGNIKRAVLGENIGTIVRGK
>Mature_239_residues
TKPKYNRVVLKLSGEALAGEKGFGINPAVIKSVAEQVKEIAELDVEVAVVVGGGNIWRGKIGSEMGMDRAGADYMGMLAT
VMNSLALQDSLENMGIQTRVQTSIEMRQVAEPYIRRKAVRHLEKKRVVIFAAGTGNPYFSTDTTAALRAAEIEADVILMA
KNNVDGVYNADPSVDPTATKYESLTYLDVLKEGLGVMDSTASSLCMDNDIPLIVFSIMEKGNIKRAVLGENIGTIVRGK

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=235, Percent_Identity=48.5106382978723, Blast_Score=234, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25902; Mature: 25771

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPKYNRVVLKLSGEALAGEKGFGINPAVIKSVAEQVKEIAELDVEVAVVVGGGNIWRG
CCCCCCCEEEEEECCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEC
KIGSEMGMDRAGADYMGMLATVMNSLALQDSLENMGIQTRVQTSIEMRQVAEPYIRRKAV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RHLEKKRVVIFAAGTGNPYFSTDTTAALRAAEIEADVILMAKNNVDGVYNADPSVDPTAT
HHHHHCEEEEEEECCCCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCEECCCCCCCCCCH
KYESLTYLDVLKEGLGVMDSTASSLCMDNDIPLIVFSIMEKGNIKRAVLGENIGTIVRGK
HHHHHHHHHHHHHHCCCHHCCHHHHHCCCCCCEEEEEHHCCCCCEEHHHCCCCCEEEECC
>Mature Secondary Structure 
TKPKYNRVVLKLSGEALAGEKGFGINPAVIKSVAEQVKEIAELDVEVAVVVGGGNIWRG
CCCCCCEEEEEECCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEC
KIGSEMGMDRAGADYMGMLATVMNSLALQDSLENMGIQTRVQTSIEMRQVAEPYIRRKAV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RHLEKKRVVIFAAGTGNPYFSTDTTAALRAAEIEADVILMAKNNVDGVYNADPSVDPTAT
HHHHHCEEEEEEECCCCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCEECCCCCCCCCCH
KYESLTYLDVLKEGLGVMDSTASSLCMDNDIPLIVFSIMEKGNIKRAVLGENIGTIVRGK
HHHHHHHHHHHHHHCCCHHCCHHHHHCCCCCCEEEEEHHCCCCCEEHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]