| Definition | Bacillus cereus subsp. cytotoxis NVH 391-98, complete genome. |
|---|---|
| Accession | NC_009674 |
| Length | 4,087,024 |
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The map label for this gene is fabG [H]
Identifier: 152976151
GI number: 152976151
Start: 2528726
End: 2529481
Strand: Reverse
Name: fabG [H]
Synonym: Bcer98_2437
Alternate gene names: 152976151
Gene position: 2529481-2528726 (Counterclockwise)
Preceding gene: 152976152
Following gene: 152976150
Centisome position: 61.89
GC content: 37.57
Gene sequence:
>756_bases ATGAAGAGTATGAATAGATGTCTTCGAAGAAAGGATCAAGAAATGAAGAAATATGCGTTAGTGACTGGGGGAAGCGGAGG AATTGGCTTTGCAATTTCAAAGCAGTTAATAGAAGATGGGTATACAGTATATATGCACTACAATAAAAATGAAGAAAAAG TAAAGGAGTTAGAAAAACAAATTGGAGAAGTCATTCCTGTTCAAGCTAACTTAGCCTGTGCGGATGGAGTAGAGAAATTG TGGGCACAGATTGATCATCCGATTGATACGATTGTATACGCAGCGGGAAAAAGTATATTTGGCTTAGTTACTGATGTGAC AAATGAACAACTTGATGAAATGATTGCATTGCAAGTGAAGAGTGTGTATAAGCTTATGTCGCTTGCATTGCCACCAATGA TACAACGGAGAAAGGGTAGTGTTGTTATTATTTCGTCAATTTGGGGGCAAATTGGAGCTTCTTGCGAAGTATTATATTCC ATGGTAAAAGGTGCACAAAATGCATATACAAAAGCTTTAGCGAAAGAAGTGGCTTTAAGTGGAATTCGTGTCAATGCAGT AGCGCCAGGGGCAATTGAAACAGAAATGTTAAGTATATTCTCAGAAGAAGATAAAAATGGAATTGCAGAGGAAATTCCAT TGGGACGAATTGGTTCCCCAAAAGAGGTGGCAAAAACAGTTTCCTTTTTAATATCACCAGGAGCTTCTTATATAACAGGT CAAATTATTGGAGTAAATGGTGGATGGTATTGCTAA
Upstream 100 bases:
>100_bases GAAATAACATACAAACATGAGGGATCTGTTGTCTGTTATATAAAAATGAACCCCTTCTTACTTTTTAGTAAAGCTTAAAA AGTAAAGAGGGGTATTTATA
Downstream 100 bases:
>100_bases AAAACATACATAAAAGATAAAAAACTGTGCAAATTAAGTATGATTGTAATACTCAATAGTGGTGAGGTGCTTAATATGTC AGTACTAGATAATTTTGATC
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+
Alternate protein names: NA
Number of amino acids: Translated: 251; Mature: 251
Protein sequence:
>251_residues MKSMNRCLRRKDQEMKKYALVTGGSGGIGFAISKQLIEDGYTVYMHYNKNEEKVKELEKQIGEVIPVQANLACADGVEKL WAQIDHPIDTIVYAAGKSIFGLVTDVTNEQLDEMIALQVKSVYKLMSLALPPMIQRRKGSVVIISSIWGQIGASCEVLYS MVKGAQNAYTKALAKEVALSGIRVNAVAPGAIETEMLSIFSEEDKNGIAEEIPLGRIGSPKEVAKTVSFLISPGASYITG QIIGVNGGWYC
Sequences:
>Translated_251_residues MKSMNRCLRRKDQEMKKYALVTGGSGGIGFAISKQLIEDGYTVYMHYNKNEEKVKELEKQIGEVIPVQANLACADGVEKL WAQIDHPIDTIVYAAGKSIFGLVTDVTNEQLDEMIALQVKSVYKLMSLALPPMIQRRKGSVVIISSIWGQIGASCEVLYS MVKGAQNAYTKALAKEVALSGIRVNAVAPGAIETEMLSIFSEEDKNGIAEEIPLGRIGSPKEVAKTVSFLISPGASYITG QIIGVNGGWYC >Mature_251_residues MKSMNRCLRRKDQEMKKYALVTGGSGGIGFAISKQLIEDGYTVYMHYNKNEEKVKELEKQIGEVIPVQANLACADGVEKL WAQIDHPIDTIVYAAGKSIFGLVTDVTNEQLDEMIALQVKSVYKLMSLALPPMIQRRKGSVVIISSIWGQIGASCEVLYS MVKGAQNAYTKALAKEVALSGIRVNAVAPGAIETEMLSIFSEEDKNGIAEEIPLGRIGSPKEVAKTVSFLISPGASYITG QIIGVNGGWYC
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=35.2, Blast_Score=120, Evalue=2e-27, Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=35.8870967741936, Blast_Score=114, Evalue=1e-25, Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=33.75, Blast_Score=109, Evalue=2e-24, Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=29.9595141700405, Blast_Score=101, Evalue=6e-22, Organism=Homo sapiens, GI19923817, Length=248, Percent_Identity=30.6451612903226, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=28.3464566929134, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI66933014, Length=207, Percent_Identity=28.0193236714976, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=34.8717948717949, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI59889578, Length=211, Percent_Identity=32.2274881516588, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI7705925, Length=239, Percent_Identity=27.1966527196653, Blast_Score=81, Evalue=7e-16, Organism=Homo sapiens, GI10190704, Length=257, Percent_Identity=25.2918287937743, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI126723191, Length=187, Percent_Identity=32.0855614973262, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI44680136, Length=220, Percent_Identity=26.8181818181818, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI44680133, Length=220, Percent_Identity=26.8181818181818, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI17738292, Length=220, Percent_Identity=26.8181818181818, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI4503301, Length=122, Percent_Identity=34.4262295081967, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=33.8912133891213, Blast_Score=132, Evalue=2e-32, Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=34.4262295081967, Blast_Score=110, Evalue=7e-26, Organism=Escherichia coli, GI87082100, Length=246, Percent_Identity=32.1138211382114, Blast_Score=100, Evalue=9e-23, Organism=Escherichia coli, GI87082160, Length=240, Percent_Identity=29.1666666666667, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1789378, Length=259, Percent_Identity=31.2741312741313, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=29.0983606557377, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1790717, Length=240, Percent_Identity=26.6666666666667, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1786812, Length=245, Percent_Identity=30.6122448979592, Blast_Score=88, Evalue=7e-19, Organism=Escherichia coli, GI2367365, Length=237, Percent_Identity=27.8481012658228, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1789208, Length=241, Percent_Identity=26.9709543568465, Blast_Score=74, Evalue=6e-15, Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=27.3469387755102, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1786701, Length=209, Percent_Identity=25.3588516746411, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=26.4367816091954, Blast_Score=65, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=35.3174603174603, Blast_Score=120, Evalue=5e-28, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=34.4, Blast_Score=103, Evalue=9e-23, Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=29.9595141700405, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=32.5490196078431, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=32.046332046332, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=29.3877551020408, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI115534694, Length=240, Percent_Identity=29.5833333333333, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17508651, Length=245, Percent_Identity=27.3469387755102, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=30.3149606299213, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=30.4182509505703, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=30.4182509505703, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=30.5882352941176, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560332, Length=264, Percent_Identity=30.3030303030303, Blast_Score=78, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=29.6577946768061, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=29.4573643410853, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=29.1187739463602, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=29.8387096774194, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=29.1187739463602, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17561272, Length=180, Percent_Identity=30, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=26.7175572519084, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=27.6923076923077, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=28.6259541984733, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=28.6274509803922, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI72000259, Length=254, Percent_Identity=28.3464566929134, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17538182, Length=245, Percent_Identity=27.7551020408163, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=27.4809160305344, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=27.8625954198473, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17508895, Length=251, Percent_Identity=25.0996015936255, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=29.8449612403101, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17563726, Length=255, Percent_Identity=29.0196078431373, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=27.4509803921569, Blast_Score=81, Evalue=2e-16, Organism=Saccharomyces cerevisiae, GI6323882, Length=215, Percent_Identity=27.4418604651163, Blast_Score=66, Evalue=4e-12, Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=34.6613545816733, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI24639444, Length=241, Percent_Identity=29.045643153527, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=32.6771653543307, Blast_Score=100, Evalue=8e-22, Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=32.258064516129, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=30.9803921568627, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=28.968253968254, Blast_Score=94, Evalue=8e-20, Organism=Drosophila melanogaster, GI24643142, Length=235, Percent_Identity=30.2127659574468, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24644337, Length=121, Percent_Identity=40.495867768595, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI17737361, Length=251, Percent_Identity=24.7011952191235, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100
Molecular weight: Translated: 27267; Mature: 27267
Theoretical pI: Translated: 7.29; Mature: 7.29
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 3.6 %Met (Translated Protein) 5.2 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 3.6 %Met (Mature Protein) 5.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKSMNRCLRRKDQEMKKYALVTGGSGGIGFAISKQLIEDGYTVYMHYNKNEEKVKELEKQ CCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHH IGEVIPVQANLACADGVEKLWAQIDHPIDTIVYAAGKSIFGLVTDVTNEQLDEMIALQVK HCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH SVYKLMSLALPPMIQRRKGSVVIISSIWGQIGASCEVLYSMVKGAQNAYTKALAKEVALS HHHHHHHHHCCHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC GIRVNAVAPGAIETEMLSIFSEEDKNGIAEEIPLGRIGSPKEVAKTVSFLISPGASYITG CEEEEEECCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCHHEEE QIIGVNGGWYC EEEEECCCCCC >Mature Secondary Structure MKSMNRCLRRKDQEMKKYALVTGGSGGIGFAISKQLIEDGYTVYMHYNKNEEKVKELEKQ CCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHH IGEVIPVQANLACADGVEKLWAQIDHPIDTIVYAAGKSIFGLVTDVTNEQLDEMIALQVK HCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH SVYKLMSLALPPMIQRRKGSVVIISSIWGQIGASCEVLYSMVKGAQNAYTKALAKEVALS HHHHHHHHHCCHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC GIRVNAVAPGAIETEMLSIFSEEDKNGIAEEIPLGRIGSPKEVAKTVSFLISPGASYITG CEEEEEECCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCHHEEE QIIGVNGGWYC EEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+
Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]