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The map label for this gene is alsR [H]

Identifier: 152976044

GI number: 152976044

Start: 2414228

End: 2415145

Strand: Reverse

Name: alsR [H]

Synonym: Bcer98_2320

Alternate gene names: 152976044

Gene position: 2415145-2414228 (Counterclockwise)

Preceding gene: 152976047

Following gene: 152976041

Centisome position: 59.09

GC content: 38.45

Gene sequence:

>918_bases
ATGGAATTACGGCATTTGCAATATTTTATTGTTGTGGCAGAAGAGCTACACTTTGGACGAGCAGCGGCTCGTTTACAAAT
GACACAGCCACCACTTAGTCAACAAATCCAACAGTTGGAGCAAGAAATGGGAGTTATGTTATTTGAAAGAACGAAGCGGA
AAGTTGAGCTTACAGAAGCGGGAGAAATGTTTTTAAAAGAAGTAAAGAAAGCTTTTGATCAAATTGAAAAGGCGGTAGAA
GTGGCGCAAAGCGCACAAAGAGGGGAAGTAGGATCTCTTTCGATTGGATTTGTGGGAGCTGCTATATACGATATTTTACC
TTCAATTGTAAGAGAATATCGAAAGAAATTTCCAAGGGTATCGGTTGCGCTTCATGAATTATCTACACCGGAGCAAGTGC
ATGCACTTCATGAAAATCGAATTGATGTCGGCTTTTTACGTCCGCCGATTTCAACGCAATTATTAGAACTTGAACCGATT
CAAAAACTACCTTGTACACTATGTTTACCAAAAGCACATCCACTTGCGGAGAAAGAAGAAATTCACATTGAAGATTTGAG
AGATGAGTCATTTGTCTTTATCACAAGACCAGTATGGCCTGCACTCTATGACACTATATTGTCATTATGCCGCGGAGTTG
GTTTTAGTCCGCGCATTGTTCAAGAGGCAACAGAATACCAAACAGTAATGGGATTAGTAGCAGCAGGAATTGGAATCACT
GTTATTCCAGTTTCGGCTAATAAGCTATACAAAACAGAAGTTGTATATAAAGATATATATGATTCTAATTTTATAGCTGA
GATGTCAGTTGCTTACCGAAAAACGAATAGTAGTCCTGAACTATTAGAGTTTTTAAAAATTGCAAGAGATAAAAAACGAA
TTGAAGTTGAAAATGAGCTGCCCGCAAAAAACTGCTGA

Upstream 100 bases:

>100_bases
ATTCATAATTTCTACTATACGTTCTTTCAAAAAGTTTGTCTAATATATAAATTATATGTTATTAATTTATTATACATATT
AATTGAAAAGGGTGTCCAAG

Downstream 100 bases:

>100_bases
TTAAAGTTCCACTTTATAAAAGGAAATGGAGCTGTTTCGTAAGTCGAATTTCTGACAACGAGACAGCTTTTTTCATATTT
TGTGAATGAATTTCTAGTAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MELRHLQYFIVVAEELHFGRAAARLQMTQPPLSQQIQQLEQEMGVMLFERTKRKVELTEAGEMFLKEVKKAFDQIEKAVE
VAQSAQRGEVGSLSIGFVGAAIYDILPSIVREYRKKFPRVSVALHELSTPEQVHALHENRIDVGFLRPPISTQLLELEPI
QKLPCTLCLPKAHPLAEKEEIHIEDLRDESFVFITRPVWPALYDTILSLCRGVGFSPRIVQEATEYQTVMGLVAAGIGIT
VIPVSANKLYKTEVVYKDIYDSNFIAEMSVAYRKTNSSPELLEFLKIARDKKRIEVENELPAKNC

Sequences:

>Translated_305_residues
MELRHLQYFIVVAEELHFGRAAARLQMTQPPLSQQIQQLEQEMGVMLFERTKRKVELTEAGEMFLKEVKKAFDQIEKAVE
VAQSAQRGEVGSLSIGFVGAAIYDILPSIVREYRKKFPRVSVALHELSTPEQVHALHENRIDVGFLRPPISTQLLELEPI
QKLPCTLCLPKAHPLAEKEEIHIEDLRDESFVFITRPVWPALYDTILSLCRGVGFSPRIVQEATEYQTVMGLVAAGIGIT
VIPVSANKLYKTEVVYKDIYDSNFIAEMSVAYRKTNSSPELLEFLKIARDKKRIEVENELPAKNC
>Mature_305_residues
MELRHLQYFIVVAEELHFGRAAARLQMTQPPLSQQIQQLEQEMGVMLFERTKRKVELTEAGEMFLKEVKKAFDQIEKAVE
VAQSAQRGEVGSLSIGFVGAAIYDILPSIVREYRKKFPRVSVALHELSTPEQVHALHENRIDVGFLRPPISTQLLELEPI
QKLPCTLCLPKAHPLAEKEEIHIEDLRDESFVFITRPVWPALYDTILSLCRGVGFSPRIVQEATEYQTVMGLVAAGIGIT
VIPVSANKLYKTEVVYKDIYDSNFIAEMSVAYRKTNSSPELLEFLKIARDKKRIEVENELPAKNC

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=286, Percent_Identity=39.1608391608392, Blast_Score=204, Evalue=4e-54,
Organism=Escherichia coli, GI2367136, Length=288, Percent_Identity=34.0277777777778, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1788887, Length=292, Percent_Identity=35.2739726027397, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1790399, Length=248, Percent_Identity=32.258064516129, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI157672245, Length=242, Percent_Identity=29.7520661157025, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI145693105, Length=245, Percent_Identity=27.3469387755102, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787530, Length=290, Percent_Identity=26.551724137931, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789204, Length=251, Percent_Identity=26.6932270916335, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI87081904, Length=150, Percent_Identity=34, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788748, Length=250, Percent_Identity=25.6, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1787806, Length=248, Percent_Identity=23.7903225806452, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788297, Length=254, Percent_Identity=25.9842519685039, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790208, Length=247, Percent_Identity=26.7206477732794, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787589, Length=123, Percent_Identity=37.3983739837398, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790262, Length=243, Percent_Identity=25.9259259259259, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789506, Length=242, Percent_Identity=24.3801652892562, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789639, Length=248, Percent_Identity=24.1935483870968, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787601, Length=177, Percent_Identity=24.2937853107345, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786401, Length=155, Percent_Identity=25.8064516129032, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787128, Length=144, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788481, Length=160, Percent_Identity=26.875, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789173, Length=257, Percent_Identity=25.6809338521401, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87082132, Length=148, Percent_Identity=31.7567567567568, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34650; Mature: 34650

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRHLQYFIVVAEELHFGRAAARLQMTQPPLSQQIQQLEQEMGVMLFERTKRKVELTEA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEHHHH
GEMFLKEVKKAFDQIEKAVEVAQSAQRGEVGSLSIGFVGAAIYDILPSIVREYRKKFPRV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCHH
SVALHELSTPEQVHALHENRIDVGFLRPPISTQLLELEPIQKLPCTLCLPKAHPLAEKEE
HHHHHHCCCHHHHHHHHHCCCCEEEECCCCCCHHEECCCHHHCCCEEECCCCCCCCCCCC
IHIEDLRDESFVFITRPVWPALYDTILSLCRGVGFSPRIVQEATEYQTVMGLVAAGIGIT
CHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEE
VIPVSANKLYKTEVVYKDIYDSNFIAEMSVAYRKTNSSPELLEFLKIARDKKRIEVENEL
EEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHEEECCCC
PAKNC
CCCCC
>Mature Secondary Structure
MELRHLQYFIVVAEELHFGRAAARLQMTQPPLSQQIQQLEQEMGVMLFERTKRKVELTEA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEHHHH
GEMFLKEVKKAFDQIEKAVEVAQSAQRGEVGSLSIGFVGAAIYDILPSIVREYRKKFPRV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCHH
SVALHELSTPEQVHALHENRIDVGFLRPPISTQLLELEPIQKLPCTLCLPKAHPLAEKEE
HHHHHHCCCHHHHHHHHHCCCCEEEECCCCCCHHEECCCHHHCCCEEECCCCCCCCCCCC
IHIEDLRDESFVFITRPVWPALYDTILSLCRGVGFSPRIVQEATEYQTVMGLVAAGIGIT
CHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEE
VIPVSANKLYKTEVVYKDIYDSNFIAEMSVAYRKTNSSPELLEFLKIARDKKRIEVENEL
EEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHEEECCCC
PAKNC
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]