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The map label for this gene is ccdA [H]

Identifier: 152976041

GI number: 152976041

Start: 2410707

End: 2411414

Strand: Reverse

Name: ccdA [H]

Synonym: Bcer98_2317

Alternate gene names: 152976041

Gene position: 2411414-2410707 (Counterclockwise)

Preceding gene: 152976044

Following gene: 152976040

Centisome position: 59.0

GC content: 36.16

Gene sequence:

>708_bases
ATGCAAGATATTAATATTTTCTTAGCGTTTGGTGCGGGATTTTTATCATTTATTTCCCCTTGTTGCTTACCGCTGTACCC
AGCGTTTTTATCTTACATAACAGGAATGTCTGTTTCTGAGCTAAAAGAAGAAAATGCGATGCTTCGTAAAAGAAGTATGC
TTCATACAGCATTTTTCTTGCTTGGATTTTCGATTGTATTTATTGCAATTGGTTTTAGTACAAGTTTTCTTGGATCCTTT
TTCAAGGACTATAAAGATTTAATTAGACAACTAGGAGCACTTTTTATTATTGTGTTTGGTCTAATCATTGTAGGAGTATT
TCAACCAAAGTTTTTAATGCAAGACCGCAAATTTACATTTAAAAGCCGGCCGAGCGGCTATATCGGCTCTATTTTAATTG
GGTTAGCGTTTGCTGCTGGGTGGACTCCGTGTACAGGTCCTATTTTAGTAGCGGTGATTGGGCTTGCTACGACAAATCTA
GAGTCCGCAATGTTATATATGATTGCATACATACTTGGGTTTGCTATTCCATTTTTTGTCCTGTCATTCTTTATTACAAA
AATGTCTTGGATAAAGCGCCATAGTGGAACGTTTGTAAAAGTCGGCGGTTACATTATGATTGTCATGGGGGTTGTTTTAT
ACTTTAATTGGATGACAAAAATCATTGTGTATTTCTCAAGTTTATTTGGCGGTTTCACAGGCTTTTAG

Upstream 100 bases:

>100_bases
TGTTTTTCATATTCGCATGCTGGAAAGTTTGAATTCATCAATTATCCATAGTATTTTTGTTTGTTTTTGCTACAATATTG
AAGAAGAGAGGAGTGAAACG

Downstream 100 bases:

>100_bases
TATGATTCCGTGAAATTGTTGGAAATACTAATAGAAAAGCATATAATGAAACTATAATTTTTTATATTGCCAAAAAAAAG
GATGAGAACGTATGAACATA

Product: cytochrome c biogenesis protein transmembrane region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MQDINIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMLHTAFFLLGFSIVFIAIGFSTSFLGSF
FKDYKDLIRQLGALFIIVFGLIIVGVFQPKFLMQDRKFTFKSRPSGYIGSILIGLAFAAGWTPCTGPILVAVIGLATTNL
ESAMLYMIAYILGFAIPFFVLSFFITKMSWIKRHSGTFVKVGGYIMIVMGVVLYFNWMTKIIVYFSSLFGGFTGF

Sequences:

>Translated_235_residues
MQDINIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMLHTAFFLLGFSIVFIAIGFSTSFLGSF
FKDYKDLIRQLGALFIIVFGLIIVGVFQPKFLMQDRKFTFKSRPSGYIGSILIGLAFAAGWTPCTGPILVAVIGLATTNL
ESAMLYMIAYILGFAIPFFVLSFFITKMSWIKRHSGTFVKVGGYIMIVMGVVLYFNWMTKIIVYFSSLFGGFTGF
>Mature_235_residues
MQDINIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMLHTAFFLLGFSIVFIAIGFSTSFLGSF
FKDYKDLIRQLGALFIIVFGLIIVGVFQPKFLMQDRKFTFKSRPSGYIGSILIGLAFAAGWTPCTGPILVAVIGLATTNL
ESAMLYMIAYILGFAIPFFVLSFFITKMSWIKRHSGTFVKVGGYIMIVMGVVLYFNWMTKIIVYFSSLFGGFTGF

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 26223; Mature: 26223

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDINIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMLHTAFFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LGFSIVFIAIGFSTSFLGSFFKDYKDLIRQLGALFIIVFGLIIVGVFQPKFLMQDRKFTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCC
KSRPSGYIGSILIGLAFAAGWTPCTGPILVAVIGLATTNLESAMLYMIAYILGFAIPFFV
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSFFITKMSWIKRHSGTFVKVGGYIMIVMGVVLYFNWMTKIIVYFSSLFGGFTGF
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQDINIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMLHTAFFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LGFSIVFIAIGFSTSFLGSFFKDYKDLIRQLGALFIIVFGLIIVGVFQPKFLMQDRKFTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCC
KSRPSGYIGSILIGLAFAAGWTPCTGPILVAVIGLATTNLESAMLYMIAYILGFAIPFFV
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSFFITKMSWIKRHSGTFVKVGGYIMIVMGVVLYFNWMTKIIVYFSSLFGGFTGF
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]