Click here to switch to the map view.

The map label for this gene is hutH [H]

Identifier: 152976036

GI number: 152976036

Start: 2406820

End: 2408337

Strand: Reverse

Name: hutH [H]

Synonym: Bcer98_2312

Alternate gene names: 152976036

Gene position: 2408337-2406820 (Counterclockwise)

Preceding gene: 152976037

Following gene: 152976035

Centisome position: 58.93

GC content: 39.72

Gene sequence:

>1518_bases
ATGGTTACGTTAACAGGACATTCATTGACAGTTGAAGAAATGAAGCGATTGCTATTTGAGAGGGAAGGGGTAACAGCTTG
CCCTGATAGCATGCAGAAAGTAGCGGAGTGCCGTGAAGCTGTTGAAAAAATTGTAGAAGATGGAAAAGTTGTATATGGTA
TTACAACTGGATTTGGTAAGTTTAGCGATGTGCTTATTCAAAAAGAGGATGTGAAAGAACTTCAACATAATTTAATTCAA
TCGCATGCTTGTGGTGTGGGTGATCCATTTCCAGAAGAAGTATCGCGAGGTATGTTAATTTTACGTGCTAATACGATGTT
AAAAGGAGTATCTGGTGTTCGTCCACTTGTTGTGAACATGTTATTAGAACTTGTAAATCGAAACATTCATCCCGTTATCC
CGCAGCAAGGTTCATTAGGTGCAAGTGGCGATTTAGCACCATTATCGCATCTTGCTCTTGTTTTATTAGGAGAAGGGGAA
GTGTTTTATAAAGGAAAGCGCGTTCATGCAATGATAGCTCTTACTGAAGAAGGTCTGGAACCAATTGAATTAGAGGCGAA
AGAAGGTCTTGCATTAATTAATGGTACACAAGCAATGACAGCCCAAGGAATTCTTTCTTATATCGAAGCGGAAACACTTG
CTTATCAGTCAGAACTAATTGCATCTATGACACTTGAAGGCTTGCGCGGCATTATTGATGCGTTTGATGAAAATGTTCAT
AAAGCGCGAGGGTATAAAGAACAGATAGAAGTAGCACAGCGTATTCGTAACATTCTTCAAGATAGTAAGCTTGTAACAAA
ACAGGGGGAACTGCGGGTACAAGATGCCTATTCATTACGCTGTATCCCTCAAGTTCATGGTGCTTCTTGGCAAGTATTAC
ATTATGTAAAAGAAAAATTAGAGATTGAAATGAACGCAGCAACCGATAATCCCCTTATTTTTGATGGAGGGGAAAAAGTG
ATTTCTGGCGGGAATTTCCATGGGCAACCAATTGCCTTTGCAATGGATTTTTTAAAGGTAGGGATGGCCGAAATTGCGAA
TATTTCAGAGCGCCGCATTGAGCGTCTTGTGAACCCGCAGTTAAATGATTTACCACCATTTTTAAGCCCTAAGCCAGGTC
TTCAGTCTGGTGCAATGATTATGCAATATGCAGCTGCTTCACTTGTATCAGAAAATAAAACATTGGCGCACCCAGCAAGT
GTTGACTCTATTCCGTCATCAGCAAACCAAGAAGATCACGTAAGTATGGGAACAATCGCTTCACGTCATGCGCATCAAAT
TATTCAAAACGTAAGACGTGTACTTGCGATTGAAATGATTTGTGCAATGCAAGCAGCGGAGTATCGTGGTATAGAAGAGA
TGAGCTCTGCAACGAAAATATTTTATCATCAAGGTCGACAGCAAGTACCTTCTATTACAAATGATCGCATATTTTCAACA
GACATTGAAAATATTGCACATTGGTTGAAAACAAGTCCGTTCACATTGGAACGTTTAAATGTAAATGCAACATTATAA

Upstream 100 bases:

>100_bases
GCCCATAGTTTATTAGTGAAAAGGGGGCCTTGCTTTTTAGGACAGAAGTCTGTCTTGAAAAGGGAAGGTCTCCTTTTGCT
TTTTTAGGAGGGAAATAAGA

Downstream 100 bases:

>100_bases
AAAGGAAAAGGGAGAGATTGAATATGGAAAACGTAAAACAAACAATTCGTGCACCAAGAGGAACAGAGTTGCAAACAAAG
GGCTGGATTCAAGAAGCTGC

Product: histidine ammonia-lyase

Products: NA

Alternate protein names: Histidase [H]

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MVTLTGHSLTVEEMKRLLFEREGVTACPDSMQKVAECREAVEKIVEDGKVVYGITTGFGKFSDVLIQKEDVKELQHNLIQ
SHACGVGDPFPEEVSRGMLILRANTMLKGVSGVRPLVVNMLLELVNRNIHPVIPQQGSLGASGDLAPLSHLALVLLGEGE
VFYKGKRVHAMIALTEEGLEPIELEAKEGLALINGTQAMTAQGILSYIEAETLAYQSELIASMTLEGLRGIIDAFDENVH
KARGYKEQIEVAQRIRNILQDSKLVTKQGELRVQDAYSLRCIPQVHGASWQVLHYVKEKLEIEMNAATDNPLIFDGGEKV
ISGGNFHGQPIAFAMDFLKVGMAEIANISERRIERLVNPQLNDLPPFLSPKPGLQSGAMIMQYAAASLVSENKTLAHPAS
VDSIPSSANQEDHVSMGTIASRHAHQIIQNVRRVLAIEMICAMQAAEYRGIEEMSSATKIFYHQGRQQVPSITNDRIFST
DIENIAHWLKTSPFTLERLNVNATL

Sequences:

>Translated_505_residues
MVTLTGHSLTVEEMKRLLFEREGVTACPDSMQKVAECREAVEKIVEDGKVVYGITTGFGKFSDVLIQKEDVKELQHNLIQ
SHACGVGDPFPEEVSRGMLILRANTMLKGVSGVRPLVVNMLLELVNRNIHPVIPQQGSLGASGDLAPLSHLALVLLGEGE
VFYKGKRVHAMIALTEEGLEPIELEAKEGLALINGTQAMTAQGILSYIEAETLAYQSELIASMTLEGLRGIIDAFDENVH
KARGYKEQIEVAQRIRNILQDSKLVTKQGELRVQDAYSLRCIPQVHGASWQVLHYVKEKLEIEMNAATDNPLIFDGGEKV
ISGGNFHGQPIAFAMDFLKVGMAEIANISERRIERLVNPQLNDLPPFLSPKPGLQSGAMIMQYAAASLVSENKTLAHPAS
VDSIPSSANQEDHVSMGTIASRHAHQIIQNVRRVLAIEMICAMQAAEYRGIEEMSSATKIFYHQGRQQVPSITNDRIFST
DIENIAHWLKTSPFTLERLNVNATL
>Mature_505_residues
MVTLTGHSLTVEEMKRLLFEREGVTACPDSMQKVAECREAVEKIVEDGKVVYGITTGFGKFSDVLIQKEDVKELQHNLIQ
SHACGVGDPFPEEVSRGMLILRANTMLKGVSGVRPLVVNMLLELVNRNIHPVIPQQGSLGASGDLAPLSHLALVLLGEGE
VFYKGKRVHAMIALTEEGLEPIELEAKEGLALINGTQAMTAQGILSYIEAETLAYQSELIASMTLEGLRGIIDAFDENVH
KARGYKEQIEVAQRIRNILQDSKLVTKQGELRVQDAYSLRCIPQVHGASWQVLHYVKEKLEIEMNAATDNPLIFDGGEKV
ISGGNFHGQPIAFAMDFLKVGMAEIANISERRIERLVNPQLNDLPPFLSPKPGLQSGAMIMQYAAASLVSENKTLAHPAS
VDSIPSSANQEDHVSMGTIASRHAHQIIQNVRRVLAIEMICAMQAAEYRGIEEMSSATKIFYHQGRQQVPSITNDRIFST
DIENIAHWLKTSPFTLERLNVNATL

Specific function: Unknown

COG id: COG2986

COG function: function code E; Histidine ammonia-lyase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAL/histidase family [H]

Homologues:

Organism=Homo sapiens, GI4504333, Length=488, Percent_Identity=44.4672131147541, Blast_Score=408, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17567831, Length=496, Percent_Identity=42.9435483870968, Blast_Score=372, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005921
- InterPro:   IPR008948
- InterPro:   IPR001106
- InterPro:   IPR022313 [H]

Pfam domain/function: PF00221 PAL [H]

EC number: =4.3.1.3 [H]

Molecular weight: Translated: 55603; Mature: 55603

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00488 PAL_HISTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLTGHSLTVEEMKRLLFEREGVTACPDSMQKVAECREAVEKIVEDGKVVYGITTGFGK
CEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCH
FSDVLIQKEDVKELQHNLIQSHACGVGDPFPEEVSRGMLILRANTMLKGVSGVRPLVVNM
HHHHHHCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCEEEEEECHHHHCCCCHHHHHHHH
LLELVNRNIHPVIPQQGSLGASGDLAPLSHLALVLLGEGEVFYKGKRVHAMIALTEEGLE
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHEEEECCCCEEEECCEEEEEEEEECCCCC
PIELEAKEGLALINGTQAMTAQGILSYIEAETLAYQSELIASMTLEGLRGIIDAFDENVH
CEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KARGYKEQIEVAQRIRNILQDSKLVTKQGELRVQDAYSLRCIPQVHGASWQVLHYVKEKL
HHCCHHHHHHHHHHHHHHHHCCHHHCCCCCEEEECCCCEEEECCCCCCCHHHHHHHHHHH
EIEMNAATDNPLIFDGGEKVISGGNFHGQPIAFAMDFLKVGMAEIANISERRIERLVNPQ
EEEEECCCCCCEEEECCHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LNDLPPFLSPKPGLQSGAMIMQYAAASLVSENKTLAHPASVDSIPSSANQEDHVSMGTIA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
SRHAHQIIQNVRRVLAIEMICAMQAAEYRGIEEMSSATKIFYHQGRQQVPSITNDRIFST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHCCCCCCCCEEHH
DIENIAHWLKTSPFTLERLNVNATL
HHHHHHHHHHCCCCEEEEECCCCCC
>Mature Secondary Structure
MVTLTGHSLTVEEMKRLLFEREGVTACPDSMQKVAECREAVEKIVEDGKVVYGITTGFGK
CEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCH
FSDVLIQKEDVKELQHNLIQSHACGVGDPFPEEVSRGMLILRANTMLKGVSGVRPLVVNM
HHHHHHCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCEEEEEECHHHHCCCCHHHHHHHH
LLELVNRNIHPVIPQQGSLGASGDLAPLSHLALVLLGEGEVFYKGKRVHAMIALTEEGLE
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHEEEECCCCEEEECCEEEEEEEEECCCCC
PIELEAKEGLALINGTQAMTAQGILSYIEAETLAYQSELIASMTLEGLRGIIDAFDENVH
CEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KARGYKEQIEVAQRIRNILQDSKLVTKQGELRVQDAYSLRCIPQVHGASWQVLHYVKEKL
HHCCHHHHHHHHHHHHHHHHCCHHHCCCCCEEEECCCCEEEECCCCCCCHHHHHHHHHHH
EIEMNAATDNPLIFDGGEKVISGGNFHGQPIAFAMDFLKVGMAEIANISERRIERLVNPQ
EEEEECCCCCCEEEECCHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LNDLPPFLSPKPGLQSGAMIMQYAAASLVSENKTLAHPASVDSIPSSANQEDHVSMGTIA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
SRHAHQIIQNVRRVLAIEMICAMQAAEYRGIEEMSSATKIFYHQGRQQVPSITNDRIFST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHCCCCCCCCEEHH
DIENIAHWLKTSPFTLERLNVNATL
HHHHHHHHHHCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA