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The map label for this gene is hutU [H]

Identifier: 152976035

GI number: 152976035

Start: 2405138

End: 2406796

Strand: Reverse

Name: hutU [H]

Synonym: Bcer98_2311

Alternate gene names: 152976035

Gene position: 2406796-2405138 (Counterclockwise)

Preceding gene: 152976036

Following gene: 152976034

Centisome position: 58.89

GC content: 42.56

Gene sequence:

>1659_bases
ATGGAAAACGTAAAACAAACAATTCGTGCACCAAGAGGAACAGAGTTGCAAACAAAGGGCTGGATTCAAGAAGCTGCACT
TCGTATGCTTATGAATAACTTAGACCCAGAAGTAGCAGAAAAGCCAGAAGAGTTAGTTGTTTATGGTGGCATTGGTCGTG
CCGCTCGCAACTGGGAGAGCTATCAGGCGATTGTTGATTCGTTAAAAACATTAGAAAGTGATGAAACGTTACTTGTTCAA
TCAGGAAAGCCGGTTGCTATTTTTAAATCACATGAAGATGCACCACGTGTTCTTTTAGCTAACTCCAATTTAGTGCCGAA
GTGGGCGAATTGGGAGCATTTTCGTGAGTTAGAACAAAAAGGGCTTATGATGTACGGACAAATGACAGCAGGTAGCTGGA
TTTATATCGGTACACAAGGAATTTTACAAGGAACATACGAAACATTTGGAGAAGCAGCGCGTCAACATTTTGGTGGTTCA
TTAAAAGGGACATTAACGCTTACGGCTGGTTTAGGCGGTATGGGGGGAGCGCAACCTCTTGCTGTTACGATGAATGGCGG
TGTGGTTATTGCAATCGATGTAGATAAACGCAGCATCGAGCGCCGCATTGAAAAAAGATATTGCGATATGTATACAGAAT
CGTTAGAAGAAGCATTAGCTGTTGCGACAGAATATAAAGAAAAGAAAGAACCTATTTCAATCGGACTATTAGGAAATGCT
GCGGAAATTTTGCCGGAGTTAGTAAGCCGCGGTATTACGCCAGATTTAGTAACGGATCAAACATCTGCACATGACCCGTT
AAATGGATATGTTCCAGCAGGATATTCGTTAGAAGAAGCTACCAAACTTCGTGCAGAAGATCCAGACCGTTACGTACAAT
TATCAAAAGAAAGCATGAAAAAACATGTAGAAGCAATGCTTGCGATGCAAGAAAAAGGTGCCATTGCGTTTGATTATGGT
AATAATATTCGTCAAGTTGCATTCGATGAAGGATTGGAACATGCATTTGATTTTCCAGGATTCGTTCCAGCGTTTATCCG
TCCGTTATTCTGTGAAGGAAAAGGTCCATTCCGTTGGGTCGCACTTTCTGGTGATCCAGAAGATATTTATAAGACAGATG
AAGTGATTTTACGCGAGTTTGCTCATAACGAGCATTTATGTAATTGGATTCGTATGGCACGTCAGCAAGTTGAATTTCAA
GGATTACCATCTCGTATTTGTTGGCTGGGTTATGGGGAACGTGCAAAATTTGGACGCATTATCAATGAAATGGTTGCAAG
CGGGGAATTATCAGCACCAATCGTGATTGGTCGTGACCATCTAGACTGTGGATCTGTAGCATCGCCAAACCGTGAAACAG
AAGGAATGAAAGATGGTAGTGATGCGGTGGCAGACTGGCCAATTTTGAATGCATTAATCAATAGTGTGAACGGTGCAAGC
TGGGTATCTGTTCATCACGGCGGTGGAGTTGGTATGGGATACTCGCTTCACGCTGGAATGGTTATTGTTGCAGACGGAAC
AGAAGCAGCAGCAAAACGAATTGAACGCGTCTTAACTTCCGATCCTGGAATGGGTGTTGTTCGCCACGTAGATGCAGGAT
ATGACTTAGCAGTTCAAACAGCGAAGGAAAAAGGCGTTAACATTCCAATGATGAAATAA

Upstream 100 bases:

>100_bases
ACATTGAAAATATTGCACATTGGTTGAAAACAAGTCCGTTCACATTGGAACGTTTAAATGTAAATGCAACATTATAAAAA
GGAAAAGGGAGAGATTGAAT

Downstream 100 bases:

>100_bases
GGAGGAACACAACATGCTGGACATTTTACTAACGAATATCGGTCAATTATTAACAATGGATCAAGAAGATGGCGTATTAA
GACAGGAAGCAATGAAGACG

Product: urocanate hydratase

Products: NA

Alternate protein names: Urocanase; Imidazolonepropionate hydrolase [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MENVKQTIRAPRGTELQTKGWIQEAALRMLMNNLDPEVAEKPEELVVYGGIGRAARNWESYQAIVDSLKTLESDETLLVQ
SGKPVAIFKSHEDAPRVLLANSNLVPKWANWEHFRELEQKGLMMYGQMTAGSWIYIGTQGILQGTYETFGEAARQHFGGS
LKGTLTLTAGLGGMGGAQPLAVTMNGGVVIAIDVDKRSIERRIEKRYCDMYTESLEEALAVATEYKEKKEPISIGLLGNA
AEILPELVSRGITPDLVTDQTSAHDPLNGYVPAGYSLEEATKLRAEDPDRYVQLSKESMKKHVEAMLAMQEKGAIAFDYG
NNIRQVAFDEGLEHAFDFPGFVPAFIRPLFCEGKGPFRWVALSGDPEDIYKTDEVILREFAHNEHLCNWIRMARQQVEFQ
GLPSRICWLGYGERAKFGRIINEMVASGELSAPIVIGRDHLDCGSVASPNRETEGMKDGSDAVADWPILNALINSVNGAS
WVSVHHGGGVGMGYSLHAGMVIVADGTEAAAKRIERVLTSDPGMGVVRHVDAGYDLAVQTAKEKGVNIPMMK

Sequences:

>Translated_552_residues
MENVKQTIRAPRGTELQTKGWIQEAALRMLMNNLDPEVAEKPEELVVYGGIGRAARNWESYQAIVDSLKTLESDETLLVQ
SGKPVAIFKSHEDAPRVLLANSNLVPKWANWEHFRELEQKGLMMYGQMTAGSWIYIGTQGILQGTYETFGEAARQHFGGS
LKGTLTLTAGLGGMGGAQPLAVTMNGGVVIAIDVDKRSIERRIEKRYCDMYTESLEEALAVATEYKEKKEPISIGLLGNA
AEILPELVSRGITPDLVTDQTSAHDPLNGYVPAGYSLEEATKLRAEDPDRYVQLSKESMKKHVEAMLAMQEKGAIAFDYG
NNIRQVAFDEGLEHAFDFPGFVPAFIRPLFCEGKGPFRWVALSGDPEDIYKTDEVILREFAHNEHLCNWIRMARQQVEFQ
GLPSRICWLGYGERAKFGRIINEMVASGELSAPIVIGRDHLDCGSVASPNRETEGMKDGSDAVADWPILNALINSVNGAS
WVSVHHGGGVGMGYSLHAGMVIVADGTEAAAKRIERVLTSDPGMGVVRHVDAGYDLAVQTAKEKGVNIPMMK
>Mature_552_residues
MENVKQTIRAPRGTELQTKGWIQEAALRMLMNNLDPEVAEKPEELVVYGGIGRAARNWESYQAIVDSLKTLESDETLLVQ
SGKPVAIFKSHEDAPRVLLANSNLVPKWANWEHFRELEQKGLMMYGQMTAGSWIYIGTQGILQGTYETFGEAARQHFGGS
LKGTLTLTAGLGGMGGAQPLAVTMNGGVVIAIDVDKRSIERRIEKRYCDMYTESLEEALAVATEYKEKKEPISIGLLGNA
AEILPELVSRGITPDLVTDQTSAHDPLNGYVPAGYSLEEATKLRAEDPDRYVQLSKESMKKHVEAMLAMQEKGAIAFDYG
NNIRQVAFDEGLEHAFDFPGFVPAFIRPLFCEGKGPFRWVALSGDPEDIYKTDEVILREFAHNEHLCNWIRMARQQVEFQ
GLPSRICWLGYGERAKFGRIINEMVASGELSAPIVIGRDHLDCGSVASPNRETEGMKDGSDAVADWPILNALINSVNGAS
WVSVHHGGGVGMGYSLHAGMVIVADGTEAAAKRIERVLTSDPGMGVVRHVDAGYDLAVQTAKEKGVNIPMMK

Specific function: Unknown

COG id: COG2987

COG function: function code E; Urocanate hydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urocanase family [H]

Homologues:

Organism=Homo sapiens, GI21389467, Length=560, Percent_Identity=35.8928571428571, Blast_Score=331, Evalue=9e-91,
Organism=Homo sapiens, GI260306182, Length=620, Percent_Identity=33.0645161290323, Blast_Score=298, Evalue=9e-81,
Organism=Caenorhabditis elegans, GI71997891, Length=551, Percent_Identity=35.934664246824, Blast_Score=340, Evalue=8e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000193 [H]

Pfam domain/function: PF01175 Urocanase [H]

EC number: =4.2.1.49 [H]

Molecular weight: Translated: 60583; Mature: 60583

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS01233 UROCANASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENVKQTIRAPRGTELQTKGWIQEAALRMLMNNLDPEVAEKPEELVVYGGIGRAARNWES
CCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEECCCCHHHHCHHH
YQAIVDSLKTLESDETLLVQSGKPVAIFKSHEDAPRVLLANSNLVPKWANWEHFRELEQK
HHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHC
GLMMYGQMTAGSWIYIGTQGILQGTYETFGEAARQHFGGSLKGTLTLTAGLGGMGGAQPL
CCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCE
AVTMNGGVVIAIDVDKRSIERRIEKRYCDMYTESLEEALAVATEYKEKKEPISIGLLGNA
EEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCH
AEILPELVSRGITPDLVTDQTSAHDPLNGYVPAGYSLEEATKLRAEDPDRYVQLSKESMK
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHH
KHVEAMLAMQEKGAIAFDYGNNIRQVAFDEGLEHAFDFPGFVPAFIRPLFCEGKGPFRWV
HHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHEECCCCCEEEE
ALSGDPEDIYKTDEVILREFAHNEHLCNWIRMARQQVEFQGLPSRICWLGYGERAKFGRI
EECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHH
INEMVASGELSAPIVIGRDHLDCGSVASPNRETEGMKDGSDAVADWPILNALINSVNGAS
HHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
WVSVHHGGGVGMGYSLHAGMVIVADGTEAAAKRIERVLTSDPGMGVVRHVDAGYDLAVQT
EEEEECCCCCCCCEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEE
AKEKGVNIPMMK
HHHCCCCCCCCC
>Mature Secondary Structure
MENVKQTIRAPRGTELQTKGWIQEAALRMLMNNLDPEVAEKPEELVVYGGIGRAARNWES
CCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEECCCCHHHHCHHH
YQAIVDSLKTLESDETLLVQSGKPVAIFKSHEDAPRVLLANSNLVPKWANWEHFRELEQK
HHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHC
GLMMYGQMTAGSWIYIGTQGILQGTYETFGEAARQHFGGSLKGTLTLTAGLGGMGGAQPL
CCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCE
AVTMNGGVVIAIDVDKRSIERRIEKRYCDMYTESLEEALAVATEYKEKKEPISIGLLGNA
EEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCH
AEILPELVSRGITPDLVTDQTSAHDPLNGYVPAGYSLEEATKLRAEDPDRYVQLSKESMK
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHH
KHVEAMLAMQEKGAIAFDYGNNIRQVAFDEGLEHAFDFPGFVPAFIRPLFCEGKGPFRWV
HHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHEECCCCCEEEE
ALSGDPEDIYKTDEVILREFAHNEHLCNWIRMARQQVEFQGLPSRICWLGYGERAKFGRI
EECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHH
INEMVASGELSAPIVIGRDHLDCGSVASPNRETEGMKDGSDAVADWPILNALINSVNGAS
HHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
WVSVHHGGGVGMGYSLHAGMVIVADGTEAAAKRIERVLTSDPGMGVVRHVDAGYDLAVQT
EEEEECCCCCCCCEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEE
AKEKGVNIPMMK
HHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA