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The map label for this gene is serC [H]

Identifier: 152975828

GI number: 152975828

Start: 2188424

End: 2189506

Strand: Reverse

Name: serC [H]

Synonym: Bcer98_2086

Alternate gene names: 152975828

Gene position: 2189506-2188424 (Counterclockwise)

Preceding gene: 152975829

Following gene: 152975827

Centisome position: 53.57

GC content: 35.83

Gene sequence:

>1083_bases
ATGGAGCGGGGGTATAATTTTTCAGCGGGGCCGTCAATGCTCCCTTTGCCAGTGTTAGAAAAAGTGCAAGCGGAGCTTTT
AAATTATAATGGGACAGGCATGTCTATAATGGAAATGAGTCACCGATCTTCATATTTTCAAGAGATTATCGAAGAAACAA
GTAGTCTGCTTCGAGAATTAATGTATATTCCAGATTCATATGATGTTTTATTTTTACAAGGGGGAGCATCTTTGCAATTT
TCAATGGTTCCACTGAATGTAATGAATAAGCATAAAAGAGCTGGATATGTATTAACAGGAACATGGGCTAAAAAGGCATT
GCAAGAGGCGAAAAAAGTCGGCGAGGCTGTTATTGTGGCTTCTTCAGAGGAAGATAATTTTACGACAATTCCTTATATAA
GTGCTTCTATGATTCCTTCAAACTTAGACTATCTACATATTACAACGAATAATACAATTGAAGGAACAAAGTATACAGAA
ATACCACAAGTTGCAACTATTCCGCTTGTCGCTGATATGTCTTCTAATATTTTATCGGAAGAATATGATGTGAATCAGTT
CGGAGTGATTTATGCAGGAGCACAAAAAAATCTAGGACCTGCTGGATTAACCATTGTAATTGTGAAAAAGGAGCTAGTGG
GGAAAGCAAAGGCTTTTTGTCCAGTTATGTTAAACTATGAAACTTATAGTAAAAATAATTCTTTATATAATACACCGCCG
TCCTTTAGTATTTATGTGACAAAGCTCGTGTTAGAATGGTTAAAAGAACAGGGCGGGGTATCTGTAATGGAACAACAAAA
TAGAAAGAAAGCAGCACTTCTGTATCAATTTTTGGATGAATCACAATTATTTACCTCACCAGTTGATCCGAAATATCGTT
CCCTTATGAATATTCCTTTTACAACACCATCGGAAAAATTGAATGAACAATTTTTACAAAAAGCAAAAGAAATGGGACTT
GTAACATTAAAAGGGCATCGTTCTGTTGGTGGTATGCGTGCAAGTATTTATAATGCAATGCCGATAGAAGGGGTGAAAAA
ATTAGTAGCGTATATGAAGACCTTTGAGTTAGAGAATAGATAG

Upstream 100 bases:

>100_bases
TATAATTAAGCAAAATGAATTGACTGAATATTCGATACGGGTTATAATTCAGAAAGTTTTAATAATATCGAATGTAAGGA
AGTAGGAGGTCATCTAGGTG

Downstream 100 bases:

>100_bases
GGGGATGAGGATATGTTTCATATTCAAACATTGAATCAAATTGCCGAAAAAGGTTTACAAGTTTTTGCAGCAGAACGATA
TAACATCGGACAAAGGATAG

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MERGYNFSAGPSMLPLPVLEKVQAELLNYNGTGMSIMEMSHRSSYFQEIIEETSSLLRELMYIPDSYDVLFLQGGASLQF
SMVPLNVMNKHKRAGYVLTGTWAKKALQEAKKVGEAVIVASSEEDNFTTIPYISASMIPSNLDYLHITTNNTIEGTKYTE
IPQVATIPLVADMSSNILSEEYDVNQFGVIYAGAQKNLGPAGLTIVIVKKELVGKAKAFCPVMLNYETYSKNNSLYNTPP
SFSIYVTKLVLEWLKEQGGVSVMEQQNRKKAALLYQFLDESQLFTSPVDPKYRSLMNIPFTTPSEKLNEQFLQKAKEMGL
VTLKGHRSVGGMRASIYNAMPIEGVKKLVAYMKTFELENR

Sequences:

>Translated_360_residues
MERGYNFSAGPSMLPLPVLEKVQAELLNYNGTGMSIMEMSHRSSYFQEIIEETSSLLRELMYIPDSYDVLFLQGGASLQF
SMVPLNVMNKHKRAGYVLTGTWAKKALQEAKKVGEAVIVASSEEDNFTTIPYISASMIPSNLDYLHITTNNTIEGTKYTE
IPQVATIPLVADMSSNILSEEYDVNQFGVIYAGAQKNLGPAGLTIVIVKKELVGKAKAFCPVMLNYETYSKNNSLYNTPP
SFSIYVTKLVLEWLKEQGGVSVMEQQNRKKAALLYQFLDESQLFTSPVDPKYRSLMNIPFTTPSEKLNEQFLQKAKEMGL
VTLKGHRSVGGMRASIYNAMPIEGVKKLVAYMKTFELENR
>Mature_360_residues
MERGYNFSAGPSMLPLPVLEKVQAELLNYNGTGMSIMEMSHRSSYFQEIIEETSSLLRELMYIPDSYDVLFLQGGASLQF
SMVPLNVMNKHKRAGYVLTGTWAKKALQEAKKVGEAVIVASSEEDNFTTIPYISASMIPSNLDYLHITTNNTIEGTKYTE
IPQVATIPLVADMSSNILSEEYDVNQFGVIYAGAQKNLGPAGLTIVIVKKELVGKAKAFCPVMLNYETYSKNNSLYNTPP
SFSIYVTKLVLEWLKEQGGVSVMEQQNRKKAALLYQFLDESQLFTSPVDPKYRSLMNIPFTTPSEKLNEQFLQKAKEMGL
VTLKGHRSVGGMRASIYNAMPIEGVKKLVAYMKTFELENR

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=357, Percent_Identity=49.5798319327731, Blast_Score=347, Evalue=1e-95,
Organism=Homo sapiens, GI10863955, Length=352, Percent_Identity=44.3181818181818, Blast_Score=289, Evalue=2e-78,
Organism=Escherichia coli, GI1787136, Length=358, Percent_Identity=46.0893854748603, Blast_Score=333, Evalue=9e-93,
Organism=Caenorhabditis elegans, GI17506897, Length=360, Percent_Identity=43.0555555555556, Blast_Score=317, Evalue=7e-87,
Organism=Saccharomyces cerevisiae, GI6324758, Length=389, Percent_Identity=40.1028277634961, Blast_Score=285, Evalue=1e-77,
Organism=Drosophila melanogaster, GI21356589, Length=361, Percent_Identity=45.983379501385, Blast_Score=328, Evalue=5e-90,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40280; Mature: 40280

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERGYNFSAGPSMLPLPVLEKVQAELLNYNGTGMSIMEMSHRSSYFQEIIEETSSLLREL
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
MYIPDSYDVLFLQGGASLQFSMVPLNVMNKHKRAGYVLTGTWAKKALQEAKKVGEAVIVA
HHCCCCCCEEEEECCCCEEEEEECHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCEEEEE
SSEEDNFTTIPYISASMIPSNLDYLHITTNNTIEGTKYTEIPQVATIPLVADMSSNILSE
ECCCCCEEECCEEEHCCCCCCCCEEEEEECCEECCCCCCCCCCEEEEEEECCCHHHHHCC
EYDVNQFGVIYAGAQKNLGPAGLTIVIVKKELVGKAKAFCPVMLNYETYSKNNSLYNTPP
CCCCCCCEEEEECCCCCCCCCCEEEEEEEHHHHHHHHCCCEEEEEEEEECCCCCCCCCCC
SFSIYVTKLVLEWLKEQGGVSVMEQQNRKKAALLYQFLDESQLFTSPVDPKYRSLMNIPF
CCHHHHHHHHHHHHHHCCCEEHHHHHCHHHHHHHHHHHCCCHHCCCCCCHHHHHHCCCCC
TTPSEKLNEQFLQKAKEMGLVTLKGHRSVGGMRASIYNAMPIEGVKKLVAYMKTFELENR
CCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MERGYNFSAGPSMLPLPVLEKVQAELLNYNGTGMSIMEMSHRSSYFQEIIEETSSLLREL
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
MYIPDSYDVLFLQGGASLQFSMVPLNVMNKHKRAGYVLTGTWAKKALQEAKKVGEAVIVA
HHCCCCCCEEEEECCCCEEEEEECHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCEEEEE
SSEEDNFTTIPYISASMIPSNLDYLHITTNNTIEGTKYTEIPQVATIPLVADMSSNILSE
ECCCCCEEECCEEEHCCCCCCCCEEEEEECCEECCCCCCCCCCEEEEEEECCCHHHHHCC
EYDVNQFGVIYAGAQKNLGPAGLTIVIVKKELVGKAKAFCPVMLNYETYSKNNSLYNTPP
CCCCCCCEEEEECCCCCCCCCCEEEEEEEHHHHHHHHCCCEEEEEEEEECCCCCCCCCCC
SFSIYVTKLVLEWLKEQGGVSVMEQQNRKKAALLYQFLDESQLFTSPVDPKYRSLMNIPF
CCHHHHHHHHHHHHHHCCCEEHHHHHCHHHHHHHHHHHCCCHHCCCCCCHHHHHHCCCCC
TTPSEKLNEQFLQKAKEMGLVTLKGHRSVGGMRASIYNAMPIEGVKKLVAYMKTFELENR
CCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA