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The map label for this gene is aroA [H]

Identifier: 152975765

GI number: 152975765

Start: 2116891

End: 2117967

Strand: Reverse

Name: aroA [H]

Synonym: Bcer98_2014

Alternate gene names: 152975765

Gene position: 2117967-2116891 (Counterclockwise)

Preceding gene: 152975766

Following gene: 152975764

Centisome position: 51.82

GC content: 38.07

Gene sequence:

>1077_bases
ATGGCAAATCATGAATTAGAACAATTACGTAAACAGGTGGATGAAATTAATTTACAGCTATTAAAGCTTTTAAATGAAAG
AGGTAGAATTGTTCAAAAAATTGGTGAACAAAAGCAACTGCAAGGAACGAAGCGCTTTGATCCCGTTCGCGAGCGCGAAG
TACTAGATATGATTGCGGAGCGTAATGAAGGGCCATTTGAGACATCGACGGTTCAACACATTTTCAAAACGATTTTCAAA
GCAAGCTTAGAGCTTCAAGAGGACGATAACCGTAAAGCGCTTCTTGTTTCCCGTAAGAAAAAACAAGAAAATACAATTGT
GGATGTAAAAGGTGAGCGATTAGGTAGTGGAACACAATCATTCATTATGGGACCTTGTGCGGTAGAAAGTTTAGAGCAAG
TTCGTCAAGTTGCGCAAGCGATAAAAGAGCAAGGATTAAAATTAATGCGCGGGGGAGCGTTCAAACCGAGAACATCACCA
TATGATTTCCAAGGTTTAGGGGTAGAAGGATTACAAATTTTACGACAAGTGGCTGATGAGTTTGATTTAGCGATTATTAG
TGAAATTTTAAATCCGAACGATGTGGAAATGGCTCTTGATTACGTTGATGTCATTCAAGTTGGGGCACGAAATATGCAAA
ACTTTGACTTATTAAGAGCTGTAGGAAAAGTGAATAAACCTGTATTGCTAAAAAGAGGTTTAGCAGCGACAATTGATGAG
TTCATGCATGCAGCTGAATACATTATTGCACAAGGTAATGATCAAATTATTTTATGTGAACGCGGCATTCGCACATACGA
AAAAGCAACTCGTAATACGTTAGATATTTCAGCAGTACCAATTTTGAAAAAAGAAACACATTTGCCAGTTGTTGTGGATG
TAACACATTCAACAGGACGCAGAGATTTATTATTACCGACTGCAAAAGCAGCGTTAGCAATTGGAGCAGATGCAGTAATG
GCAGAAGTACATCCAGACCCAGCTGTTGCATTATCTGACTCAGCACAGCAAATGGATATTCCAGAATTCCATAGATTCAT
GGAAGAGTTAAAAGAATTCAAAAATAAATTATCGTAA

Upstream 100 bases:

>100_bases
GGTATCGATTTCATATGATAACGATTTAGTTTATGGATTCAGAAAATAAGGAATTTTATTTCTCTTACTATACTTTTACA
CATTTGAGGAGGATATGAAA

Downstream 100 bases:

>100_bases
GTTCATATAGAATATGCGAAGAAAGGGAAACAGTAGTGTTTATCTCCCTATTTATAGAGAGCTGATGGATGGTGAAAATC
AGTACAAAGATAAACATGAA

Product: bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase

Products: NA

Alternate protein names: Phospho-2-dehydro-3-deoxyheptonate aldolase; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase; Chorismate mutase [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MANHELEQLRKQVDEINLQLLKLLNERGRIVQKIGEQKQLQGTKRFDPVREREVLDMIAERNEGPFETSTVQHIFKTIFK
ASLELQEDDNRKALLVSRKKKQENTIVDVKGERLGSGTQSFIMGPCAVESLEQVRQVAQAIKEQGLKLMRGGAFKPRTSP
YDFQGLGVEGLQILRQVADEFDLAIISEILNPNDVEMALDYVDVIQVGARNMQNFDLLRAVGKVNKPVLLKRGLAATIDE
FMHAAEYIIAQGNDQIILCERGIRTYEKATRNTLDISAVPILKKETHLPVVVDVTHSTGRRDLLLPTAKAALAIGADAVM
AEVHPDPAVALSDSAQQMDIPEFHRFMEELKEFKNKLS

Sequences:

>Translated_358_residues
MANHELEQLRKQVDEINLQLLKLLNERGRIVQKIGEQKQLQGTKRFDPVREREVLDMIAERNEGPFETSTVQHIFKTIFK
ASLELQEDDNRKALLVSRKKKQENTIVDVKGERLGSGTQSFIMGPCAVESLEQVRQVAQAIKEQGLKLMRGGAFKPRTSP
YDFQGLGVEGLQILRQVADEFDLAIISEILNPNDVEMALDYVDVIQVGARNMQNFDLLRAVGKVNKPVLLKRGLAATIDE
FMHAAEYIIAQGNDQIILCERGIRTYEKATRNTLDISAVPILKKETHLPVVVDVTHSTGRRDLLLPTAKAALAIGADAVM
AEVHPDPAVALSDSAQQMDIPEFHRFMEELKEFKNKLS
>Mature_357_residues
ANHELEQLRKQVDEINLQLLKLLNERGRIVQKIGEQKQLQGTKRFDPVREREVLDMIAERNEGPFETSTVQHIFKTIFKA
SLELQEDDNRKALLVSRKKKQENTIVDVKGERLGSGTQSFIMGPCAVESLEQVRQVAQAIKEQGLKLMRGGAFKPRTSPY
DFQGLGVEGLQILRQVADEFDLAIISEILNPNDVEMALDYVDVIQVGARNMQNFDLLRAVGKVNKPVLLKRGLAATIDEF
MHAAEYIIAQGNDQIILCERGIRTYEKATRNTLDISAVPILKKETHLPVVVDVTHSTGRRDLLLPTAKAALAIGADAVMA
EVHPDPAVALSDSAQQMDIPEFHRFMEELKEFKNKLS

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 chorismate mutase domain [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=216, Percent_Identity=29.6296296296296, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002701
- InterPro:   IPR010954
- InterPro:   IPR020822
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF01817 CM_2; PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54; =5.4.99.5 [H]

Molecular weight: Translated: 40213; Mature: 40082

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANHELEQLRKQVDEINLQLLKLLNERGRIVQKIGEQKQLQGTKRFDPVREREVLDMIAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHHH
RNEGPFETSTVQHIFKTIFKASLELQEDDNRKALLVSRKKKQENTIVDVKGERLGSGTQS
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHCCCCEEEECCCCCCCCCHH
FIMGPCAVESLEQVRQVAQAIKEQGLKLMRGGAFKPRTSPYDFQGLGVEGLQILRQVADE
HHCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FDLAIISEILNPNDVEMALDYVDVIQVGARNMQNFDLLRAVGKVNKPVLLKRGLAATIDE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHCCHHHHHHH
FMHAAEYIIAQGNDQIILCERGIRTYEKATRNTLDISAVPILKKETHLPVVVDVTHSTGR
HHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCEEECCCEECCCCCCEEEEECCCCCC
RDLLLPTAKAALAIGADAVMAEVHPDPAVALSDSAQQMDIPEFHRFMEELKEFKNKLS
CCEECHHHHHHHHHCCHHHHHCCCCCCCEEECCCHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANHELEQLRKQVDEINLQLLKLLNERGRIVQKIGEQKQLQGTKRFDPVREREVLDMIAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHHH
RNEGPFETSTVQHIFKTIFKASLELQEDDNRKALLVSRKKKQENTIVDVKGERLGSGTQS
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHCCCCEEEECCCCCCCCCHH
FIMGPCAVESLEQVRQVAQAIKEQGLKLMRGGAFKPRTSPYDFQGLGVEGLQILRQVADE
HHCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FDLAIISEILNPNDVEMALDYVDVIQVGARNMQNFDLLRAVGKVNKPVLLKRGLAATIDE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHCCHHHHHHH
FMHAAEYIIAQGNDQIILCERGIRTYEKATRNTLDISAVPILKKETHLPVVVDVTHSTGR
HHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCEEECCCEECCCCCCEEEEECCCCCC
RDLLLPTAKAALAIGADAVMAEVHPDPAVALSDSAQQMDIPEFHRFMEELKEFKNKLS
CCEECHHHHHHHHHCCHHHHHCCCCCCCEEECCCHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7496534; 9387221; 9384377 [H]