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The map label for this gene is clpP1 [H]

Identifier: 152975675

GI number: 152975675

Start: 2023524

End: 2024108

Strand: Reverse

Name: clpP1 [H]

Synonym: Bcer98_1910

Alternate gene names: 152975675

Gene position: 2024108-2023524 (Counterclockwise)

Preceding gene: 152975676

Following gene: 152975673

Centisome position: 49.53

GC content: 36.58

Gene sequence:

>585_bases
ATGATGAATACAATTCCATATGTTGTGGAACAAACAAAGTTAGGAGAACGCTCCTATGATATATATTCTAGATTATTAAA
AGATCGTATTGTGATGATTGGTTCAGAAATTAATGATCAAGTTGCAAGTAGTGTAGTGGCGCAGTTATTGTTTTTAGAAG
CAGAAGATGCAGAAAAAGATATTTTTCTTTATATTAATAGTCCAGGTGGTTCGACGACAGCAGGATTTGCGATTTTAGAT
ACAATGAACTTGATTAAGCCAGATGTACAAACGCTTTGTATGGGCTTGGCAGCATCATTTGGGGCACTTTTGTTGCTTAG
CGGAACAAAAGGAAAACGATTTGCGCTCCCAAATAGTGAAATTATGATTCACCAGCCGCTTGGCGGAGCAAAAGGGCAAG
CGACAGAGATTGAAATAACAGCAAAGCGGATATTAAAGTTAAAACAAGATATTAACAATATTATATCTGACCGAACAGGG
CAACCAATTGAAAAAGTAGCGCGTGATACAGAAAGAGATTACTTTATGACGGCAGAAGAAGCAAAAACATACGGGATTGT
TGATGCGGTTATTACAAAAAAATAA

Upstream 100 bases:

>100_bases
ACATGTATCTTCTAAAGAGCCGGTGCTATTGTTCAGTGCGAAAAAATCTTCTTCTTACAATTTTATGTTATGTGCAGCTT
AACAATAAGATGGAGGGATT

Downstream 100 bases:

>100_bases
TGGAAAGCAGGCTAGGAACATAATTTATTTCCTAGCCTGTTTTTATACGGTGCATTATTCTTTCATCCACTCATTCACAA
GTCTTTGGTTCTTTTTAATC

Product: ATP-dependent Clp protease, proteolytic subunit ClpP

Products: NA

Alternate protein names: Endopeptidase Clp 1 [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MMNTIPYVVEQTKLGERSYDIYSRLLKDRIVMIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILD
TMNLIKPDVQTLCMGLAASFGALLLLSGTKGKRFALPNSEIMIHQPLGGAKGQATEIEITAKRILKLKQDINNIISDRTG
QPIEKVARDTERDYFMTAEEAKTYGIVDAVITKK

Sequences:

>Translated_194_residues
MMNTIPYVVEQTKLGERSYDIYSRLLKDRIVMIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILD
TMNLIKPDVQTLCMGLAASFGALLLLSGTKGKRFALPNSEIMIHQPLGGAKGQATEIEITAKRILKLKQDINNIISDRTG
QPIEKVARDTERDYFMTAEEAKTYGIVDAVITKK
>Mature_194_residues
MMNTIPYVVEQTKLGERSYDIYSRLLKDRIVMIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILD
TMNLIKPDVQTLCMGLAASFGALLLLSGTKGKRFALPNSEIMIHQPLGGAKGQATEIEITAKRILKLKQDINNIISDRTG
QPIEKVARDTERDYFMTAEEAKTYGIVDAVITKK

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=189, Percent_Identity=55.026455026455, Blast_Score=212, Evalue=2e-55,
Organism=Escherichia coli, GI1786641, Length=193, Percent_Identity=59.5854922279793, Blast_Score=255, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI17538017, Length=190, Percent_Identity=49.4736842105263, Blast_Score=199, Evalue=7e-52,
Organism=Drosophila melanogaster, GI20129427, Length=190, Percent_Identity=54.7368421052632, Blast_Score=219, Evalue=8e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 21334; Mature: 21334

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00382 CLP_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNTIPYVVEQTKLGERSYDIYSRLLKDRIVMIGSEINDQVASSVVAQLLFLEAEDAEKD
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCCCCCE
IFLYINSPGGSTTAGFAILDTMNLIKPDVQTLCMGLAASFGALLLLSGTKGKRFALPNSE
EEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCEEEEEECCCCCEEECCCCC
IMIHQPLGGAKGQATEIEITAKRILKLKQDINNIISDRTGQPIEKVARDTERDYFMTAEE
EEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEHHH
AKTYGIVDAVITKK
HHHHHHHHHHCCCC
>Mature Secondary Structure
MMNTIPYVVEQTKLGERSYDIYSRLLKDRIVMIGSEINDQVASSVVAQLLFLEAEDAEKD
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCCCCCE
IFLYINSPGGSTTAGFAILDTMNLIKPDVQTLCMGLAASFGALLLLSGTKGKRFALPNSE
EEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCEEEEEECCCCCEEECCCCC
IMIHQPLGGAKGQATEIEITAKRILKLKQDINNIISDRTGQPIEKVARDTERDYFMTAEE
EEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEHHH
AKTYGIVDAVITKK
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]