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The map label for this gene is thrC [H]

Identifier: 152975290

GI number: 152975290

Start: 1605750

End: 1606808

Strand: Direct

Name: thrC [H]

Synonym: Bcer98_1497

Alternate gene names: 152975290

Gene position: 1605750-1606808 (Clockwise)

Preceding gene: 152975289

Following gene: 152975291

Centisome position: 39.29

GC content: 40.23

Gene sequence:

>1059_bases
ATGTATAAAGGGTTATTAAAACAATATGCTTCTTATTTACCTGTGAGCCACAATACACCAGAGGTTAGTTTGATGGAGGG
AAATACACCGCTTATTCCGCTTGAAAATATCTCTGAAAAATTAGGGATATGTTTATACGGAAAATATGAAGGAGCAAATC
CAACCGGTTCGTTTAAAGATCGCGGTATGGTAATGGCAGTTGCAAAAGCAAAAGAGATGGGTTCAAAAGCCATTATTTGT
GCTTCGACAGGGAATACTTCGGCATCTGCAGCAGCATATGCGGCTCGCCTTGGAATGAAATGTATTATCGTTATACCGGA
AGGTAAAATTGCTCATGGAAAGTTAGCACAGGCGTTTGCATATGGTGCAGAAATTATTTCGATAGAAGGAAATTTTGATG
ATGCGCTGCGAGCAGTGCGACAAATCGCGGCCGAAGAGTCTATTACATTAGTAAACTCTGTTAATCCGTATCGGATTGAA
GGGCAGAAAACAGCTGCGTTTGAAATTTGTGATCAGTTGCAAAAAGCGCCAGATGTTCTTGCTATTCCAGTTGGAAATGC
TGGGAATATTACTGCATATTGGAAAGGTTTTTGTGAATACGAGAAAGAGAAAGGGTATAAAAAACCAAGAATCCATGGGT
TTGAAGCGGAAGGTGCAGCAGCGATTGTAAAAGGTCATGTCATTGAAGGACCAGAAACAATTGCAACTGCAATTCGAATT
GGCAATCCTGCAAGCTGGCATTATGCAGTGGAGGCTGCTGAACAGTCGAACGGTGAAATTGATATGGTATCGGATGAAGA
GATTGTAAAGGCTTATCAATTGCTAGCGAGAACAGAAGGAGTGTTTGCTGAACCAGGTTCCAACGCTTCTTTAGCGGGGA
TCATTAAACATGTTCAATTAGGTAAAATTCGTCAAGGAGAGACAGTCGTCGCTGTATTAACAGGAAATGGTTTGAAAGAT
CCGGATATCGCAATCTCCTCGAATTCATTACAAATTACAAATATCTCAAATGATTTAGAACAAATGAAAGGTCATATTAA
GGGAGTGATTATTTCGTGA

Upstream 100 bases:

>100_bases
CATCAAACTTCCAAATATCAATTTTCACAAGTCTTACAGTTATTAGAGGATGTCGCAAGTGAAATAAAAAGTTACTACAG
TATTGAGGAGGAAAAACAAT

Downstream 100 bases:

>100_bases
TACCATTTAAAATTCGTGTTCCAGCGAGTACAGCAAATATAGGCCCTGGTTTTGATTCTGTAGGGATGGCACTATCTTTA
TATTTAGAAGTTATTGTGAA

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MYKGLLKQYASYLPVSHNTPEVSLMEGNTPLIPLENISEKLGICLYGKYEGANPTGSFKDRGMVMAVAKAKEMGSKAIIC
ASTGNTSASAAAYAARLGMKCIIVIPEGKIAHGKLAQAFAYGAEIISIEGNFDDALRAVRQIAAEESITLVNSVNPYRIE
GQKTAAFEICDQLQKAPDVLAIPVGNAGNITAYWKGFCEYEKEKGYKKPRIHGFEAEGAAAIVKGHVIEGPETIATAIRI
GNPASWHYAVEAAEQSNGEIDMVSDEEIVKAYQLLARTEGVFAEPGSNASLAGIIKHVQLGKIRQGETVVAVLTGNGLKD
PDIAISSNSLQITNISNDLEQMKGHIKGVIIS

Sequences:

>Translated_352_residues
MYKGLLKQYASYLPVSHNTPEVSLMEGNTPLIPLENISEKLGICLYGKYEGANPTGSFKDRGMVMAVAKAKEMGSKAIIC
ASTGNTSASAAAYAARLGMKCIIVIPEGKIAHGKLAQAFAYGAEIISIEGNFDDALRAVRQIAAEESITLVNSVNPYRIE
GQKTAAFEICDQLQKAPDVLAIPVGNAGNITAYWKGFCEYEKEKGYKKPRIHGFEAEGAAAIVKGHVIEGPETIATAIRI
GNPASWHYAVEAAEQSNGEIDMVSDEEIVKAYQLLARTEGVFAEPGSNASLAGIIKHVQLGKIRQGETVVAVLTGNGLKD
PDIAISSNSLQITNISNDLEQMKGHIKGVIIS
>Mature_352_residues
MYKGLLKQYASYLPVSHNTPEVSLMEGNTPLIPLENISEKLGICLYGKYEGANPTGSFKDRGMVMAVAKAKEMGSKAIIC
ASTGNTSASAAAYAARLGMKCIIVIPEGKIAHGKLAQAFAYGAEIISIEGNFDDALRAVRQIAAEESITLVNSVNPYRIE
GQKTAAFEICDQLQKAPDVLAIPVGNAGNITAYWKGFCEYEKEKGYKKPRIHGFEAEGAAAIVKGHVIEGPETIATAIRI
GNPASWHYAVEAAEQSNGEIDMVSDEEIVKAYQLLARTEGVFAEPGSNASLAGIIKHVQLGKIRQGETVVAVLTGNGLKD
PDIAISSNSLQITNISNDLEQMKGHIKGVIIS

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=289, Percent_Identity=29.757785467128, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI295821202, Length=216, Percent_Identity=32.8703703703704, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI295821200, Length=216, Percent_Identity=32.8703703703704, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI4557415, Length=216, Percent_Identity=32.8703703703704, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1790207, Length=299, Percent_Identity=28.4280936454849, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI2367138, Length=206, Percent_Identity=29.126213592233, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71991565, Length=306, Percent_Identity=28.4313725490196, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322631, Length=275, Percent_Identity=30.5454545454545, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24643623, Length=189, Percent_Identity=34.3915343915344, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI20129101, Length=189, Percent_Identity=34.3915343915344, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: 1344 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 37524; Mature: 37524

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKGLLKQYASYLPVSHNTPEVSLMEGNTPLIPLENISEKLGICLYGKYEGANPTGSFKD
CCHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEHHHHHHHCCEEEEEEECCCCCCCCCCC
RGMVMAVAKAKEMGSKAIICASTGNTSASAAAYAARLGMKCIIVIPEGKIAHGKLAQAFA
CCEEEEEEEHHHCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHH
YGAEIISIEGNFDDALRAVRQIAAEESITLVNSVNPYRIEGQKTAAFEICDQLQKAPDVL
CCEEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCHHHHHHHHHHHCCCCEE
AIPVGNAGNITAYWKGFCEYEKEKGYKKPRIHGFEAEGAAAIVKGHVIEGPETIATAIRI
EEECCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECEEECCCHHHHHEEEC
GNPASWHYAVEAAEQSNGEIDMVSDEEIVKAYQLLARTEGVFAEPGSNASLAGIIKHVQL
CCCCCEEEEEEEHHCCCCCEEEECCHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHH
GKIRQGETVVAVLTGNGLKDPDIAISSNSLQITNISNDLEQMKGHIKGVIIS
CCCCCCCEEEEEEECCCCCCCCEEEECCCEEEEECHHHHHHHHHHHCEEEEC
>Mature Secondary Structure
MYKGLLKQYASYLPVSHNTPEVSLMEGNTPLIPLENISEKLGICLYGKYEGANPTGSFKD
CCHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEHHHHHHHCCEEEEEEECCCCCCCCCCC
RGMVMAVAKAKEMGSKAIICASTGNTSASAAAYAARLGMKCIIVIPEGKIAHGKLAQAFA
CCEEEEEEEHHHCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHH
YGAEIISIEGNFDDALRAVRQIAAEESITLVNSVNPYRIEGQKTAAFEICDQLQKAPDVL
CCEEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCHHHHHHHHHHHCCCCEE
AIPVGNAGNITAYWKGFCEYEKEKGYKKPRIHGFEAEGAAAIVKGHVIEGPETIATAIRI
EEECCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECEEECCCHHHHHEEEC
GNPASWHYAVEAAEQSNGEIDMVSDEEIVKAYQLLARTEGVFAEPGSNASLAGIIKHVQL
CCCCCEEEEEEEHHCCCCCEEEECCHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHH
GKIRQGETVVAVLTGNGLKDPDIAISSNSLQITNISNDLEQMKGHIKGVIIS
CCCCCCCEEEEEEECCCCCCCCEEEECCCEEEEECHHHHHHHHHHHCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3186450; 8768250 [H]