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The map label for this gene is hblA [H]

Identifier: 152975262

GI number: 152975262

Start: 1574769

End: 1575830

Strand: Direct

Name: hblA [H]

Synonym: Bcer98_1467

Alternate gene names: 152975262

Gene position: 1574769-1575830 (Clockwise)

Preceding gene: 152975261

Following gene: 152975263

Centisome position: 38.53

GC content: 34.75

Gene sequence:

>1062_bases
ATGTACAAGCATTTCTATCAAAAATGTCTATTATCTATCATGATTATTGGAGTCACAATAAATCATGCATTTCCTCTGCA
TTCTGTTGCCGAAGAACAAAAAGGTGCAGGAAATGATTCTCTTGGTCCAGCAGGCTTTCAAGAGGCAATGGTGCAAACAA
CATCAAGCATTTTTGCAATGGATTCATATGCAAAATTAATTCTTGATCAACAAGAAACAGATTTACATAAGATAAACTCC
ATTCACGGTGATGTAAGACGAGATATAATCCAACATCAAAGAGATGCAAAAATGAATGCAACAAATTGGACCCATCAAAT
GAAACCACAAATTATGAAAGTGGATCAAAAGATTATCGATTTTCATACTATTTTTCAAGCGCAATACAACAGCATGCTAT
TGGCAGTTGATCAGAAAGATCGTGACACATTAAAAGCGAATTTAGAAACATTGTATACGAACATTTTACGCAATCAAAAG
GAAGTAGATGCTTTATTAGAGGAGTTAAAAGCGTTCCGGGAGAGAATGGTGAAAGATACAACTCGTTTTAAAAATGATGC
GGATCAATTAACTGCGATTTTGGCAAGTACAAATGCAGGGATTCCAGCGCTAGAGCAACAAATTCAGACATATAATGATT
CTATAAAAAAGAGCAATGACATGGTCATAGCTGGAGGTGTACTTTGTGTGACTTTACTTACCTGTCTTGCAGGTGGACCG
ATGATTGCTGTGGCTAAAAAAGATATTGCAAATGCTGAGCGAGAAATCGCGAATGTAAAGGCAAAAATTTCTGGAGTACA
AGCGGAGATTGCCATTTTAACAGACGTGAAAAATAAGACAATAAATATGACAGAAACAATTGATGCCGCAATTACAGCGT
TACAAAATATTTCAAATCAATGGTATATAGTAGGGGCAAAATATAATAACTTATTGCAAAATGTAAAAGGAATTAGCCCT
GAAGAGTTTCATTTTATTAAAGAAGATTTGAATGTAGCAAAAGATAGTTGGAGGGATGTAAAAACATATACAGAAAAACT
GCACGAAAGCATAAAAAAGTAG

Upstream 100 bases:

>100_bases
ATATTCAAGTAGTAGATAGGGAAAAAGTATAATGCTCTTTTAATTTATATATTTTTATGTAACAATTTATAATATGTGCA
ATAAAGAATAGGGGAAAAAT

Downstream 100 bases:

>100_bases
TAGATAGAATCTACTGCTTTTTTTGTCTTCGTTTTGATAGAGGGGAGGAAAGGTCGAATAGTCGAAATTTCGAGAATAAA
CCTGTATAATGCTTGTAATG

Product: haemolytic enterotoxin

Products: NA

Alternate protein names: Enterotoxin 40 kDa subunit [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MYKHFYQKCLLSIMIIGVTINHAFPLHSVAEEQKGAGNDSLGPAGFQEAMVQTTSSIFAMDSYAKLILDQQETDLHKINS
IHGDVRRDIIQHQRDAKMNATNWTHQMKPQIMKVDQKIIDFHTIFQAQYNSMLLAVDQKDRDTLKANLETLYTNILRNQK
EVDALLEELKAFRERMVKDTTRFKNDADQLTAILASTNAGIPALEQQIQTYNDSIKKSNDMVIAGGVLCVTLLTCLAGGP
MIAVAKKDIANAEREIANVKAKISGVQAEIAILTDVKNKTINMTETIDAAITALQNISNQWYIVGAKYNNLLQNVKGISP
EEFHFIKEDLNVAKDSWRDVKTYTEKLHESIKK

Sequences:

>Translated_353_residues
MYKHFYQKCLLSIMIIGVTINHAFPLHSVAEEQKGAGNDSLGPAGFQEAMVQTTSSIFAMDSYAKLILDQQETDLHKINS
IHGDVRRDIIQHQRDAKMNATNWTHQMKPQIMKVDQKIIDFHTIFQAQYNSMLLAVDQKDRDTLKANLETLYTNILRNQK
EVDALLEELKAFRERMVKDTTRFKNDADQLTAILASTNAGIPALEQQIQTYNDSIKKSNDMVIAGGVLCVTLLTCLAGGP
MIAVAKKDIANAEREIANVKAKISGVQAEIAILTDVKNKTINMTETIDAAITALQNISNQWYIVGAKYNNLLQNVKGISP
EEFHFIKEDLNVAKDSWRDVKTYTEKLHESIKK
>Mature_353_residues
MYKHFYQKCLLSIMIIGVTINHAFPLHSVAEEQKGAGNDSLGPAGFQEAMVQTTSSIFAMDSYAKLILDQQETDLHKINS
IHGDVRRDIIQHQRDAKMNATNWTHQMKPQIMKVDQKIIDFHTIFQAQYNSMLLAVDQKDRDTLKANLETLYTNILRNQK
EVDALLEELKAFRERMVKDTTRFKNDADQLTAILASTNAGIPALEQQIQTYNDSIKKSNDMVIAGGVLCVTLLTCLAGGP
MIAVAKKDIANAEREIANVKAKISGVQAEIAILTDVKNKTINMTETIDAAITALQNISNQWYIVGAKYNNLLQNVKGISP
EEFHFIKEDLNVAKDSWRDVKTYTEKLHESIKK

Specific function: Cytotoxic protein, part of the enterotoxin complex. Responsible for binding to erythrocytes. This enterotoxin is thought to be the cause of the diarrheal form of gastroenteritis caused by food-borne strains of B.cereus [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008414
- InterPro:   IPR010356 [H]

Pfam domain/function: PF05791 Bacillus_HBL [H]

EC number: NA

Molecular weight: Translated: 39725; Mature: 39725

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKHFYQKCLLSIMIIGVTINHAFPLHSVAEEQKGAGNDSLGPAGFQEAMVQTTSSIFAM
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
DSYAKLILDQQETDLHKINSIHGDVRRDIIQHQRDAKMNATNWTHQMKPQIMKVDQKIID
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCHHHHHHHHHHHH
FHTIFQAQYNSMLLAVDQKDRDTLKANLETLYTNILRNQKEVDALLEELKAFRERMVKDT
HHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
TRFKNDADQLTAILASTNAGIPALEQQIQTYNDSIKKSNDMVIAGGVLCVTLLTCLAGGP
HHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCC
MIAVAKKDIANAEREIANVKAKISGVQAEIAILTDVKNKTINMTETIDAAITALQNISNQ
EEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCC
WYIVGAKYNNLLQNVKGISPEEFHFIKEDLNVAKDSWRDVKTYTEKLHESIKK
EEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYKHFYQKCLLSIMIIGVTINHAFPLHSVAEEQKGAGNDSLGPAGFQEAMVQTTSSIFAM
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
DSYAKLILDQQETDLHKINSIHGDVRRDIIQHQRDAKMNATNWTHQMKPQIMKVDQKIID
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCHHHHHHHHHHHH
FHTIFQAQYNSMLLAVDQKDRDTLKANLETLYTNILRNQKEVDALLEELKAFRERMVKDT
HHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
TRFKNDADQLTAILASTNAGIPALEQQIQTYNDSIKKSNDMVIAGGVLCVTLLTCLAGGP
HHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCC
MIAVAKKDIANAEREIANVKAKISGVQAEIAILTDVKNKTINMTETIDAAITALQNISNQ
EEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCC
WYIVGAKYNNLLQNVKGISPEEFHFIKEDLNVAKDSWRDVKTYTEKLHESIKK
EEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7693651; 8319899 [H]