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The map label for this gene is hblA [H]

Identifier: 152975261

GI number: 152975261

Start: 1573495

End: 1574700

Strand: Direct

Name: hblA [H]

Synonym: Bcer98_1466

Alternate gene names: 152975261

Gene position: 1573495-1574700 (Clockwise)

Preceding gene: 152975260

Following gene: 152975262

Centisome position: 38.5

GC content: 35.16

Gene sequence:

>1206_bases
ATGAATAAAAAACCTTCTAAAGTAATGACTTTATCAGCACTTATGATGGTGTTTGCAGCAGGAAATATGATGCCAGCGCA
TACTTTTGCAGCAGAAAATATGAAATCAGTTTCAGTTCATGCGGTGGCGAAAGCATATCATGAATATGAAGAGTATTCAC
TAGGTCCAGAGGGATTAAAAGATGCAATGGAACGCACTGGTTCGAATGCTTTAGTAATGGATTTATATGCTTTAACAATA
ATAAAACAAGGAAATGTTAGTTTTGGAAATGTAACAACGGTTGATGCTCCTTTAAGGGCAAAAATTGTGCAGCACCAAAA
TACAGCGCGAAGTAATGCAAAACAATGGTTAGATGTATTGAAGCCGCAGCTTATTTCTACAAATCAAAATATCATTAATT
ATAATACGAAATTCCAAAATTATTATGATACTTTAGTGAAAGCTGTAGATACGAAAGATAAAGCAACTCTGACAAAGGGA
TTAACAAGGTTGTCTAATAGTATTACAGAAAATAAAGAACAAGTTGACAAGTTAGTAGAAGATTTGAAACGATTCCGGAA
TAAAATGACAGCAGATACACAAAACTTCAAAACGGATGCAAATCAAATTACATCTATTTTAGCTAGTCAAGACGCAGGAA
TTCCACTATTGCAAAGTCAAATCACAACATACAATGAGGCGATGAGTAAGTATAATGCACTTATTATTGGTTCCTCTGTA
GCCACAGCTTTAGGCCCAATTGCGATTATAGGTGGTACAGTTGTCATCGCCACTGGAGCGGGAACGCCGTTAGGAGTGGC
ACTAATCGCAGGCGGTACAGCAGCAGTAGGTGGAGGTACAACGGGAATTGTTTTAGCAAAAAAAGAACTTGACAATGCAC
AGGCAGAAATTCAAAAAATAACAGGTAAAATTACTACTGCACAATTAGAAGTAGCAGGGTTAACAAATATTAAAATGCAA
ACAGAATATTTAACAAATACAATTGACACTGCGATTACAGCGTTACAAAATATTTCAAATCAGTGGCATACAATGGGAGC
AAAATATCATTCATTACTTCAAAATGTAGATTCTATTAGTCCTGAAGAGCTTGTGTTTATGAAAGAAGATCTTAGCATCG
CAAAAGATAGCTGGAAAAATATTAAAGATTATGCGGAGAAAATTTATGCTGAGGATATTCAAGTAGTAGATAGGGAAAAA
GTATAA

Upstream 100 bases:

>100_bases
GATAAAAAAACAAACGAGTCAATTTGAAGATTACATTACGAACGTCGAAGTACATTCGTGAAAAAAGCATACATATTGCA
TGATTAGGGAGAGAAAGAAA

Downstream 100 bases:

>100_bases
TGCTCTTTTAATTTATATATTTTTATGTAACAATTTATAATATGTGCAATAAAGAATAGGGGAAAAATATGTACAAGCAT
TTCTATCAAAAATGTCTATT

Product: haemolytic enterotoxin

Products: NA

Alternate protein names: Enterotoxin 40 kDa subunit [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MNKKPSKVMTLSALMMVFAAGNMMPAHTFAAENMKSVSVHAVAKAYHEYEEYSLGPEGLKDAMERTGSNALVMDLYALTI
IKQGNVSFGNVTTVDAPLRAKIVQHQNTARSNAKQWLDVLKPQLISTNQNIINYNTKFQNYYDTLVKAVDTKDKATLTKG
LTRLSNSITENKEQVDKLVEDLKRFRNKMTADTQNFKTDANQITSILASQDAGIPLLQSQITTYNEAMSKYNALIIGSSV
ATALGPIAIIGGTVVIATGAGTPLGVALIAGGTAAVGGGTTGIVLAKKELDNAQAEIQKITGKITTAQLEVAGLTNIKMQ
TEYLTNTIDTAITALQNISNQWHTMGAKYHSLLQNVDSISPEELVFMKEDLSIAKDSWKNIKDYAEKIYAEDIQVVDREK
V

Sequences:

>Translated_401_residues
MNKKPSKVMTLSALMMVFAAGNMMPAHTFAAENMKSVSVHAVAKAYHEYEEYSLGPEGLKDAMERTGSNALVMDLYALTI
IKQGNVSFGNVTTVDAPLRAKIVQHQNTARSNAKQWLDVLKPQLISTNQNIINYNTKFQNYYDTLVKAVDTKDKATLTKG
LTRLSNSITENKEQVDKLVEDLKRFRNKMTADTQNFKTDANQITSILASQDAGIPLLQSQITTYNEAMSKYNALIIGSSV
ATALGPIAIIGGTVVIATGAGTPLGVALIAGGTAAVGGGTTGIVLAKKELDNAQAEIQKITGKITTAQLEVAGLTNIKMQ
TEYLTNTIDTAITALQNISNQWHTMGAKYHSLLQNVDSISPEELVFMKEDLSIAKDSWKNIKDYAEKIYAEDIQVVDREK
V
>Mature_401_residues
MNKKPSKVMTLSALMMVFAAGNMMPAHTFAAENMKSVSVHAVAKAYHEYEEYSLGPEGLKDAMERTGSNALVMDLYALTI
IKQGNVSFGNVTTVDAPLRAKIVQHQNTARSNAKQWLDVLKPQLISTNQNIINYNTKFQNYYDTLVKAVDTKDKATLTKG
LTRLSNSITENKEQVDKLVEDLKRFRNKMTADTQNFKTDANQITSILASQDAGIPLLQSQITTYNEAMSKYNALIIGSSV
ATALGPIAIIGGTVVIATGAGTPLGVALIAGGTAAVGGGTTGIVLAKKELDNAQAEIQKITGKITTAQLEVAGLTNIKMQ
TEYLTNTIDTAITALQNISNQWHTMGAKYHSLLQNVDSISPEELVFMKEDLSIAKDSWKNIKDYAEKIYAEDIQVVDREK
V

Specific function: Cytotoxic protein, part of the enterotoxin complex. Responsible for binding to erythrocytes. This enterotoxin is thought to be the cause of the diarrheal form of gastroenteritis caused by food-borne strains of B.cereus [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008414
- InterPro:   IPR010356 [H]

Pfam domain/function: PF05791 Bacillus_HBL [H]

EC number: NA

Molecular weight: Translated: 43614; Mature: 43614

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKPSKVMTLSALMMVFAAGNMMPAHTFAAENMKSVSVHAVAKAYHEYEEYSLGPEGLK
CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHH
DAMERTGSNALVMDLYALTIIKQGNVSFGNVTTVDAPLRAKIVQHQNTARSNAKQWLDVL
HHHHHCCCCHHHHHHHHHHHEECCCCCCCCEEEECCHHHHHHHHHCCHHHHHHHHHHHHH
KPQLISTNQNIINYNTKFQNYYDTLVKAVDTKDKATLTKGLTRLSNSITENKEQVDKLVE
CHHHCCCCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
DLKRFRNKMTADTQNFKTDANQITSILASQDAGIPLLQSQITTYNEAMSKYNALIIGSSV
HHHHHHHHHCCCCHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCEEEECCHH
ATALGPIAIIGGTVVIATGAGTPLGVALIAGGTAAVGGGTTGIVLAKKELDNAQAEIQKI
HHHHCCHHEECCEEEEEECCCCCCEEEEEECCCEECCCCCEEEEEEHHHHHHHHHHHHHH
TGKITTAQLEVAGLTNIKMQTEYLTNTIDTAITALQNISNQWHTMGAKYHSLLQNVDSIS
HCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PEELVFMKEDLSIAKDSWKNIKDYAEKIYAEDIQVVDREKV
HHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKKPSKVMTLSALMMVFAAGNMMPAHTFAAENMKSVSVHAVAKAYHEYEEYSLGPEGLK
CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHH
DAMERTGSNALVMDLYALTIIKQGNVSFGNVTTVDAPLRAKIVQHQNTARSNAKQWLDVL
HHHHHCCCCHHHHHHHHHHHEECCCCCCCCEEEECCHHHHHHHHHCCHHHHHHHHHHHHH
KPQLISTNQNIINYNTKFQNYYDTLVKAVDTKDKATLTKGLTRLSNSITENKEQVDKLVE
CHHHCCCCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
DLKRFRNKMTADTQNFKTDANQITSILASQDAGIPLLQSQITTYNEAMSKYNALIIGSSV
HHHHHHHHHCCCCHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCEEEECCHH
ATALGPIAIIGGTVVIATGAGTPLGVALIAGGTAAVGGGTTGIVLAKKELDNAQAEIQKI
HHHHCCHHEECCEEEEEECCCCCCEEEEEECCCEECCCCCEEEEEEHHHHHHHHHHHHHH
TGKITTAQLEVAGLTNIKMQTEYLTNTIDTAITALQNISNQWHTMGAKYHSLLQNVDSIS
HCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PEELVFMKEDLSIAKDSWKNIKDYAEKIYAEDIQVVDREKV
HHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7693651; 8319899 [H]