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The map label for this gene is dppE [H]

Identifier: 152975256

GI number: 152975256

Start: 1566740

End: 1568368

Strand: Direct

Name: dppE [H]

Synonym: Bcer98_1461

Alternate gene names: 152975256

Gene position: 1566740-1568368 (Clockwise)

Preceding gene: 152975255

Following gene: 152975257

Centisome position: 38.33

GC content: 34.32

Gene sequence:

>1629_bases
ATGAAGCAAGAAAAGAGTCGCTTACTTATGCTTACTATTATGACATTTTTTATTTTAGCAGCTTGTAATAAAAGCGAGGA
TAAAATACATAAAGAAGCTCAAAAACAAGTGTTAAACGTAACGATAGCAGAAGAAATGCCATCTCTTGATGTAGCGAAAG
CAATGGATGGCACATCGGCACATGTAATGCAAAATATATTTGAAGGATTATATGTATTAGATCGTGATGATAAACCAATC
CCTGGTGTTGCCGAGTCATTTGAGAAAAGCGGAGATGGTAAGAAATATACATTTCATTTGCGCAAAAATGCAAAATGGTC
CAATGGTGAATCGGTAACTGCACATGATTTCATTTTTTCTTGGAAGCGAACATTAGCCTCTGACACAGCCTCTCCCTATG
CTTACATGTTATTTGACATAAAAAATGCAAAAGAAATAAATAAAGGTGAATTACATGTAGATCAACTGGGAGCGAAAGCG
TTAGATGATTATACATTAGAGGTACAATTAAATAGGCCTATTCCTTATTTTCTACAATTGTTAACATTGCCGATTTATTT
ACCGCAACATGAACCATTTGTGAAAGAACAAGGGGAACGTTATGGGTTAGAACCTAACCAACTTATTTATAATGGGGCAT
TTGTACTAGAGGAATGGAAGCATGAGCAAGAGTTTCAGTTGAAGAGAAACGAGACATATTGGGATAAAGAAAAAGTGAAA
TTAGACGAAATAAATTTTCACATTGTAAAAGATACAGCGACAGCTGTGAATTTGTATGAATCTGGCGTACTTGATCGAAC
ACCTATTAATTCTACCTTTGTAGATCGTTACAAAAATAACAAAGAGTTACACATGTCAAGTGAATCAGCAATTGCTATGC
TTCGCTTTCATGAAGGAGATGCGTTACTAGCAAACAAAAAAGTTCGCCAGGCCATTTCATTTGCCATAAATAAAAAAGAA
ATGGTAAATCATTTTATTAATAATGGTGCAGTTCCTGCATATGGCTTAATTCCTAGCGGATATGAAAATGAAGTAACTAA
AAAAGATTTTCGGAAGGAAAATGGAGAGATCGCAGGTTATGACGTTGAAAAAGCAAAGGAACTTTGGAGTGAAGCGAAAA
AAGAGCTTGGTACTGAAAAGGTTACGATAGAATTTCTGACATTTGAGCAAGATAATGCAAAACGCCTAGCGGAGTATATA
AAAGGAGAGTTAGAAAAACATTTAAGCGGTTTAACATTACAAATTAAACAGCAACCATTCAAACAAAAATTACAATTAGA
GCAAACTGGACAGTACGATATTTCAATGGTCATATGGGGACCTGATTATAAGGATCCCATTAATTACTTAGAATTATTTA
CGACAGATAGTCCGAATAATCGGATGCAATATTCTAATCCCGATTATGATAACTTAATTAAGCAGGCTAAATATGATATT
GTATTAGATTCAAAGAAAAGATGGGAAACCTTGCAACTAGCGGAACGAATCATATTGGAAGATGCAGCTGTGGCACCTCT
TTATTATAAAGGTTCTGCATATATGCAAAAAGAATATGTAAAAGGAATTGAAGAACATCAATTCGGTGGCATATATACGT
ACAAATTTGCCTATATAGATAAGAAATAA

Upstream 100 bases:

>100_bases
AGCGGATAAAGATTCATGGAGGTGTAACACTTTTTCAGTAAACTTTCTGCTATAATAAAGAGCGTTTTATAATAATTATT
GAATGTAAGGAGAATAATTC

Downstream 100 bases:

>100_bases
TAGAGACTTGCTACAAGAAAGAGTAGAGTGCTTGAGTGAAAAGTGCTTTACTGCTCTTATTTTCTCGAATGTAAAGAGGT
TTAAAAACTTATGGAGCAGA

Product: extracellular solute-binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MKQEKSRLLMLTIMTFFILAACNKSEDKIHKEAQKQVLNVTIAEEMPSLDVAKAMDGTSAHVMQNIFEGLYVLDRDDKPI
PGVAESFEKSGDGKKYTFHLRKNAKWSNGESVTAHDFIFSWKRTLASDTASPYAYMLFDIKNAKEINKGELHVDQLGAKA
LDDYTLEVQLNRPIPYFLQLLTLPIYLPQHEPFVKEQGERYGLEPNQLIYNGAFVLEEWKHEQEFQLKRNETYWDKEKVK
LDEINFHIVKDTATAVNLYESGVLDRTPINSTFVDRYKNNKELHMSSESAIAMLRFHEGDALLANKKVRQAISFAINKKE
MVNHFINNGAVPAYGLIPSGYENEVTKKDFRKENGEIAGYDVEKAKELWSEAKKELGTEKVTIEFLTFEQDNAKRLAEYI
KGELEKHLSGLTLQIKQQPFKQKLQLEQTGQYDISMVIWGPDYKDPINYLELFTTDSPNNRMQYSNPDYDNLIKQAKYDI
VLDSKKRWETLQLAERIILEDAAVAPLYYKGSAYMQKEYVKGIEEHQFGGIYTYKFAYIDKK

Sequences:

>Translated_542_residues
MKQEKSRLLMLTIMTFFILAACNKSEDKIHKEAQKQVLNVTIAEEMPSLDVAKAMDGTSAHVMQNIFEGLYVLDRDDKPI
PGVAESFEKSGDGKKYTFHLRKNAKWSNGESVTAHDFIFSWKRTLASDTASPYAYMLFDIKNAKEINKGELHVDQLGAKA
LDDYTLEVQLNRPIPYFLQLLTLPIYLPQHEPFVKEQGERYGLEPNQLIYNGAFVLEEWKHEQEFQLKRNETYWDKEKVK
LDEINFHIVKDTATAVNLYESGVLDRTPINSTFVDRYKNNKELHMSSESAIAMLRFHEGDALLANKKVRQAISFAINKKE
MVNHFINNGAVPAYGLIPSGYENEVTKKDFRKENGEIAGYDVEKAKELWSEAKKELGTEKVTIEFLTFEQDNAKRLAEYI
KGELEKHLSGLTLQIKQQPFKQKLQLEQTGQYDISMVIWGPDYKDPINYLELFTTDSPNNRMQYSNPDYDNLIKQAKYDI
VLDSKKRWETLQLAERIILEDAAVAPLYYKGSAYMQKEYVKGIEEHQFGGIYTYKFAYIDKK
>Mature_542_residues
MKQEKSRLLMLTIMTFFILAACNKSEDKIHKEAQKQVLNVTIAEEMPSLDVAKAMDGTSAHVMQNIFEGLYVLDRDDKPI
PGVAESFEKSGDGKKYTFHLRKNAKWSNGESVTAHDFIFSWKRTLASDTASPYAYMLFDIKNAKEINKGELHVDQLGAKA
LDDYTLEVQLNRPIPYFLQLLTLPIYLPQHEPFVKEQGERYGLEPNQLIYNGAFVLEEWKHEQEFQLKRNETYWDKEKVK
LDEINFHIVKDTATAVNLYESGVLDRTPINSTFVDRYKNNKELHMSSESAIAMLRFHEGDALLANKKVRQAISFAINKKE
MVNHFINNGAVPAYGLIPSGYENEVTKKDFRKENGEIAGYDVEKAKELWSEAKKELGTEKVTIEFLTFEQDNAKRLAEYI
KGELEKHLSGLTLQIKQQPFKQKLQLEQTGQYDISMVIWGPDYKDPINYLELFTTDSPNNRMQYSNPDYDNLIKQAKYDI
VLDSKKRWETLQLAERIILEDAAVAPLYYKGSAYMQKEYVKGIEEHQFGGIYTYKFAYIDKK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=503, Percent_Identity=31.8091451292247, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI87081878, Length=502, Percent_Identity=30.4780876494024, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1789397, Length=501, Percent_Identity=28.3433133732535, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1789966, Length=458, Percent_Identity=27.292576419214, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787762, Length=542, Percent_Identity=23.9852398523985, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1787052, Length=432, Percent_Identity=23.6111111111111, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789887, Length=444, Percent_Identity=25.9009009009009, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 62692; Mature: 62692

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00496 PII_GLNB_UMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQEKSRLLMLTIMTFFILAACNKSEDKIHKEAQKQVLNVTIAEEMPSLDVAKAMDGTSA
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEHHHCCCCHHHHHCCCCHH
HVMQNIFEGLYVLDRDDKPIPGVAESFEKSGDGKKYTFHLRKNAKWSNGESVTAHDFIFS
HHHHHHHCCEEEEECCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEHHHHHHH
WKRTLASDTASPYAYMLFDIKNAKEINKGELHVDQLGAKALDDYTLEVQLNRPIPYFLQL
HHHHHHCCCCCCEEEEEEEECCCCCCCCCCEEHHHHCCHHCCCEEEEEEECCCCHHHHHH
LTLPIYLPQHEPFVKEQGERYGLEPNQLIYNGAFVLEEWKHEQEFQLKRNETYWDKEKVK
HHHHEECCCCCCHHHHCCCCCCCCCCCEEECCCHHHHHHCCCHHHHHCCCCCCCCHHCEE
LDEINFHIVKDTATAVNLYESGVLDRTPINSTFVDRYKNNKELHMSSESAIAMLRFHEGD
EECCEEEEEECCHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEECCCCEEEEEEEECCC
ALLANKKVRQAISFAINKKEMVNHFINNGAVPAYGLIPSGYENEVTKKDFRKENGEIAGY
EEHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCC
DVEKAKELWSEAKKELGTEKVTIEFLTFEQDNAKRLAEYIKGELEKHLSGLTLQIKQQPF
CHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCHH
KQKLQLEQTGQYDISMVIWGPDYKDPINYLELFTTDSPNNRMQYSNPDYDNLIKQAKYDI
HHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCE
VLDSKKRWETLQLAERIILEDAAVAPLYYKGSAYMQKEYVKGIEEHQFGGIYTYKFAYID
EECCHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCHHHCCCCCEEEEEEEEEE
KK
CC
>Mature Secondary Structure
MKQEKSRLLMLTIMTFFILAACNKSEDKIHKEAQKQVLNVTIAEEMPSLDVAKAMDGTSA
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEHHHCCCCHHHHHCCCCHH
HVMQNIFEGLYVLDRDDKPIPGVAESFEKSGDGKKYTFHLRKNAKWSNGESVTAHDFIFS
HHHHHHHCCEEEEECCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEHHHHHHH
WKRTLASDTASPYAYMLFDIKNAKEINKGELHVDQLGAKALDDYTLEVQLNRPIPYFLQL
HHHHHHCCCCCCEEEEEEEECCCCCCCCCCEEHHHHCCHHCCCEEEEEEECCCCHHHHHH
LTLPIYLPQHEPFVKEQGERYGLEPNQLIYNGAFVLEEWKHEQEFQLKRNETYWDKEKVK
HHHHEECCCCCCHHHHCCCCCCCCCCCEEECCCHHHHHHCCCHHHHHCCCCCCCCHHCEE
LDEINFHIVKDTATAVNLYESGVLDRTPINSTFVDRYKNNKELHMSSESAIAMLRFHEGD
EECCEEEEEECCHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEECCCCEEEEEEEECCC
ALLANKKVRQAISFAINKKEMVNHFINNGAVPAYGLIPSGYENEVTKKDFRKENGEIAGY
EEHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCC
DVEKAKELWSEAKKELGTEKVTIEFLTFEQDNAKRLAEYIKGELEKHLSGLTLQIKQQPF
CHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCHH
KQKLQLEQTGQYDISMVIWGPDYKDPINYLELFTTDSPNNRMQYSNPDYDNLIKQAKYDI
HHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCE
VLDSKKRWETLQLAERIILEDAAVAPLYYKGSAYMQKEYVKGIEEHQFGGIYTYKFAYID
EECCHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCHHHCCCCCEEEEEEEEEE
KK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]