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The map label for this gene is hepT [H]

Identifier: 152975037

GI number: 152975037

Start: 1347054

End: 1348016

Strand: Direct

Name: hepT [H]

Synonym: Bcer98_1237

Alternate gene names: 152975037

Gene position: 1347054-1348016 (Clockwise)

Preceding gene: 152975036

Following gene: 152975038

Centisome position: 32.96

GC content: 37.28

Gene sequence:

>963_bases
ATGAAGTTACAACTTATGTACTCTTTTTTACGATCAGATATTAATGTGATAGAAAAAGAATTAAAAAAGACGGTTGCTTC
TGAGCAACCGTTAGTGGAAGAAGCAGCATTGCAACTGATTGAAGCTGGTGGGAAACGAATTCGTCCTGTATTTGTACTTC
TTGCAGGGAAATTTGGGGAATATAAATTAGATGCGATTAAGCATGTAGCGGTTGCATTAGAACTTATTCATATGGCATCC
CTTGTTCATGATGATGTGATTGACGCTGCTCTATTGCGACGTGGCAGTGCAACAGTGAATGCAAACTGGGGAGATCGTAT
TGCGATGTATACGGGAGATTATTTATTTGCAAAATCTCTTGAATGCATTACGAATCTAGAGGTTCCAGAAGCTCATCAAG
CCTTGTCTTATACAATTTTAGAAGTATGTAAAGGTGAGATTGAACAAATTAAAGACAAGTATAATTATGATCAAAACTTA
CGAACATATTTGCGTAGAATTAAGAGAAAAACGGCGCTACTCATTGCCGCGAGTTGTCAGTTAGGTGCAATTGCTTCTGG
GGCAAGTCGCGATACGGTAAATCGCTTGTTTTGGTATGGGTATTTTGTCGGCATGTCGTATCAAATTATCGATGATATTT
TAGATTTTGTTTCGACAGAAGAGAAACTTGGCAAACCTGCTGGTGGAGATTTATTACAGGGGAATGTTACACTTCCAGCT
TTGTATGCGATGGAAGATTCGAAGCTTCGAGAGAAAATTGTATCTGTTCATGAAAATACAACAGCAAGCGAAATGAAGGA
AATAATCCATGCTATTAAAATGAGTCCGGCAATTGATCGAGCATTTGCATTTAGTGAACGTTATTTACATAAAGCTTTAG
AAGTGATTAAACCATTGCCTAGAGGACAGGCGAAATATGCTTTGCAAAATGTAGCAAAGTATATTGGAAAAAGAAAATTT
TAA

Upstream 100 bases:

>100_bases
ATACAAGTAAAACCATTTACCTTTGGAGTAGCTGCTATGCATTTAGGGGTTAAGCCAGAATCAGAGTAGAAAAAAGATGT
TTTAGGTTAAGGTGAACAAT

Downstream 100 bases:

>100_bases
TATTTTTTCTAAAAAACAAAAAAATCTCTCTATTTCAAAACTATTGCACAATTACGATAAGGGTGTTAATATGTGTGTGG
GGATATACAATTACATACAT

Product: heptaprenyl diphosphate synthase component II

Products: NA

Alternate protein names: HEPPP synthase subunit 2; Spore germination protein C3 [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKLQLMYSFLRSDINVIEKELKKTVASEQPLVEEAALQLIEAGGKRIRPVFVLLAGKFGEYKLDAIKHVAVALELIHMAS
LVHDDVIDAALLRRGSATVNANWGDRIAMYTGDYLFAKSLECITNLEVPEAHQALSYTILEVCKGEIEQIKDKYNYDQNL
RTYLRRIKRKTALLIAASCQLGAIASGASRDTVNRLFWYGYFVGMSYQIIDDILDFVSTEEKLGKPAGGDLLQGNVTLPA
LYAMEDSKLREKIVSVHENTTASEMKEIIHAIKMSPAIDRAFAFSERYLHKALEVIKPLPRGQAKYALQNVAKYIGKRKF

Sequences:

>Translated_320_residues
MKLQLMYSFLRSDINVIEKELKKTVASEQPLVEEAALQLIEAGGKRIRPVFVLLAGKFGEYKLDAIKHVAVALELIHMAS
LVHDDVIDAALLRRGSATVNANWGDRIAMYTGDYLFAKSLECITNLEVPEAHQALSYTILEVCKGEIEQIKDKYNYDQNL
RTYLRRIKRKTALLIAASCQLGAIASGASRDTVNRLFWYGYFVGMSYQIIDDILDFVSTEEKLGKPAGGDLLQGNVTLPA
LYAMEDSKLREKIVSVHENTTASEMKEIIHAIKMSPAIDRAFAFSERYLHKALEVIKPLPRGQAKYALQNVAKYIGKRKF
>Mature_320_residues
MKLQLMYSFLRSDINVIEKELKKTVASEQPLVEEAALQLIEAGGKRIRPVFVLLAGKFGEYKLDAIKHVAVALELIHMAS
LVHDDVIDAALLRRGSATVNANWGDRIAMYTGDYLFAKSLECITNLEVPEAHQALSYTILEVCKGEIEQIKDKYNYDQNL
RTYLRRIKRKTALLIAASCQLGAIASGASRDTVNRLFWYGYFVGMSYQIIDDILDFVSTEEKLGKPAGGDLLQGNVTLPA
LYAMEDSKLREKIVSVHENTTASEMKEIIHAIKMSPAIDRAFAFSERYLHKALEVIKPLPRGQAKYALQNVAKYIGKRKF

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=310, Percent_Identity=28.7096774193548, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI169808399, Length=324, Percent_Identity=22.5308641975309, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI4758430, Length=225, Percent_Identity=24.8888888888889, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI83700220, Length=225, Percent_Identity=24.8888888888889, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1789578, Length=321, Percent_Identity=27.7258566978193, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1786623, Length=223, Percent_Identity=30.4932735426009, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17505681, Length=314, Percent_Identity=30.8917197452229, Blast_Score=142, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6319475, Length=298, Percent_Identity=28.1879194630872, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24651612, Length=301, Percent_Identity=28.5714285714286, Blast_Score=142, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 35962; Mature: 35962

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLQLMYSFLRSDINVIEKELKKTVASEQPLVEEAALQLIEAGGKRIRPVFVLLAGKFGE
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHCHHHEEEECCCCC
YKLDAIKHVAVALELIHMASLVHDDVIDAALLRRGSATVNANWGDRIAMYTGDYLFAKSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEECCHHHHHHH
ECITNLEVPEAHQALSYTILEVCKGEIEQIKDKYNYDQNLRTYLRRIKRKTALLIAASCQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEECCC
LGAIASGASRDTVNRLFWYGYFVGMSYQIIDDILDFVSTEEKLGKPAGGDLLQGNVTLPA
CCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEECCCCCCH
LYAMEDSKLREKIVSVHENTTASEMKEIIHAIKMSPAIDRAFAFSERYLHKALEVIKPLP
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
RGQAKYALQNVAKYIGKRKF
CCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLQLMYSFLRSDINVIEKELKKTVASEQPLVEEAALQLIEAGGKRIRPVFVLLAGKFGE
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHCHHHEEEECCCCC
YKLDAIKHVAVALELIHMASLVHDDVIDAALLRRGSATVNANWGDRIAMYTGDYLFAKSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEECCHHHHHHH
ECITNLEVPEAHQALSYTILEVCKGEIEQIKDKYNYDQNLRTYLRRIKRKTALLIAASCQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEECCC
LGAIASGASRDTVNRLFWYGYFVGMSYQIIDDILDFVSTEEKLGKPAGGDLLQGNVTLPA
CCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEECCCCCCH
LYAMEDSKLREKIVSVHENTTASEMKEIIHAIKMSPAIDRAFAFSERYLHKALEVIKPLP
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
RGQAKYALQNVAKYIGKRKF
CCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 2121900; 9720033 [H]