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The map label for this gene is ubiE [H]

Identifier: 152975036

GI number: 152975036

Start: 1346309

End: 1347022

Strand: Direct

Name: ubiE [H]

Synonym: Bcer98_1236

Alternate gene names: 152975036

Gene position: 1346309-1347022 (Clockwise)

Preceding gene: 152975035

Following gene: 152975037

Centisome position: 32.94

GC content: 37.68

Gene sequence:

>714_bases
ATGCAGCAATCAAAAGAAGAAAGAGTACATGATGTCTTTGAGAAAATCTCTGATAAATATGATGTAATGAATTCAGTAAT
TAGTTTTCAAAGACATAAAGCGTGGCGCAAAGAAACAATGCGCATTATGGATGTTAAACCTGGTAGTAAAGCATTAGATG
TATGCTGTGGAACCGCAGATTGGACGATTGCACTTGCGAATGCAGTAGGGCCAAATGGTGAGGTGAAAGGTTTAGACTTC
AGCGAAAATATGCTAGCTGTTGGGAAAGAAAAGGTGAAGGCTTTAGGATTAGAGCAAGTAGAACTTATGCATGGGAATGC
GATGGAACTTCCATTTGAGGATCATACATTTGATTACGTAACAATTGGATTTGGTTTGCGGAATGTTCCAGATTATATGC
ACGTATTGAAAGAAATGACACGAGTAGTCAAACCTGGCGGAAAAGTCATTTGTTTGGAGACATCACAACCAACGATGATT
GGTTTTCGTCAAATATACATCTTATATTTCAAATATATAATGCCGTTATTTGGAAAAATATTTGCGAAAAGTTATAAGGA
ATACTCCTGGCTTCAAGAGTCAGCAAGTACATTTCCAGGAATGAAGGAATTAGCAAGAATGTTTGAAGATGCTGGACTTG
AGCGAATACAAGTAAAACCATTTACCTTTGGAGTAGCTGCTATGCATTTAGGGGTTAAGCCAGAATCAGAGTAG

Upstream 100 bases:

>100_bases
AATATTTTTGAAAAATCATAAAGAATTTGGAGATATCGTTTCTACTTTAAAAGGCAAATTGAACACTTAAGCAATTTTAT
ATTGGAAGAAGGGTAAGAGC

Downstream 100 bases:

>100_bases
AAAAAAGATGTTTTAGGTTAAGGTGAACAATATGAAGTTACAACTTATGTACTCTTTTTTACGATCAGATATTAATGTGA
TAGAAAAAGAATTAAAAAAG

Product: ubiquinone/menaquinone biosynthesis methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MQQSKEERVHDVFEKISDKYDVMNSVISFQRHKAWRKETMRIMDVKPGSKALDVCCGTADWTIALANAVGPNGEVKGLDF
SENMLAVGKEKVKALGLEQVELMHGNAMELPFEDHTFDYVTIGFGLRNVPDYMHVLKEMTRVVKPGGKVICLETSQPTMI
GFRQIYILYFKYIMPLFGKIFAKSYKEYSWLQESASTFPGMKELARMFEDAGLERIQVKPFTFGVAAMHLGVKPESE

Sequences:

>Translated_237_residues
MQQSKEERVHDVFEKISDKYDVMNSVISFQRHKAWRKETMRIMDVKPGSKALDVCCGTADWTIALANAVGPNGEVKGLDF
SENMLAVGKEKVKALGLEQVELMHGNAMELPFEDHTFDYVTIGFGLRNVPDYMHVLKEMTRVVKPGGKVICLETSQPTMI
GFRQIYILYFKYIMPLFGKIFAKSYKEYSWLQESASTFPGMKELARMFEDAGLERIQVKPFTFGVAAMHLGVKPESE
>Mature_237_residues
MQQSKEERVHDVFEKISDKYDVMNSVISFQRHKAWRKETMRIMDVKPGSKALDVCCGTADWTIALANAVGPNGEVKGLDF
SENMLAVGKEKVKALGLEQVELMHGNAMELPFEDHTFDYVTIGFGLRNVPDYMHVLKEMTRVVKPGGKVICLETSQPTMI
GFRQIYILYFKYIMPLFGKIFAKSYKEYSWLQESASTFPGMKELARMFEDAGLERIQVKPFTFGVAAMHLGVKPESE

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: COG2226

COG function: function code H; Methylase involved in ubiquinone/menaquinone biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Homo sapiens, GI116063536, Length=266, Percent_Identity=33.4586466165414, Blast_Score=151, Evalue=5e-37,
Organism=Escherichia coli, GI48994983, Length=233, Percent_Identity=38.6266094420601, Blast_Score=175, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17557039, Length=236, Percent_Identity=33.8983050847458, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17561380, Length=183, Percent_Identity=24.5901639344262, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6323526, Length=253, Percent_Identity=28.8537549407115, Blast_Score=108, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24641702, Length=243, Percent_Identity=34.5679012345679, Blast_Score=150, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014122
- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.-

Molecular weight: Translated: 26952; Mature: 26952

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS01183 UBIE_1 ; PS01184 UBIE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQSKEERVHDVFEKISDKYDVMNSVISFQRHKAWRKETMRIMDVKPGSKALDVCCGTAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHCCCCC
WTIALANAVGPNGEVKGLDFSENMLAVGKEKVKALGLEQVELMHGNAMELPFEDHTFDYV
CEEEEECCCCCCCCEECCCCCCCHHHHHHHHHHHHCHHHHHHHCCCEEECCCCCCCCCEE
TIGFGLRNVPDYMHVLKEMTRVVKPGGKVICLETSQPTMIGFRQIYILYFKYIMPLFGKI
EECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
FAKSYKEYSWLQESASTFPGMKELARMFEDAGLERIQVKPFTFGVAAMHLGVKPESE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCEEHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQQSKEERVHDVFEKISDKYDVMNSVISFQRHKAWRKETMRIMDVKPGSKALDVCCGTAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHCCCCC
WTIALANAVGPNGEVKGLDFSENMLAVGKEKVKALGLEQVELMHGNAMELPFEDHTFDYV
CEEEEECCCCCCCCEECCCCCCCHHHHHHHHHHHHCHHHHHHHCCCEEECCCCCCCCCEE
TIGFGLRNVPDYMHVLKEMTRVVKPGGKVICLETSQPTMIGFRQIYILYFKYIMPLFGKI
EECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
FAKSYKEYSWLQESASTFPGMKELARMFEDAGLERIQVKPFTFGVAAMHLGVKPESE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCEEHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA