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The map label for this gene is engA [H]

Identifier: 152975027

GI number: 152975027

Start: 1338270

End: 1339580

Strand: Direct

Name: engA [H]

Synonym: Bcer98_1227

Alternate gene names: 152975027

Gene position: 1338270-1339580 (Clockwise)

Preceding gene: 152975026

Following gene: 152975028

Centisome position: 32.74

GC content: 40.05

Gene sequence:

>1311_bases
ATGCCAAAACCAGTAGTGGCAATAGTGGGACGCCCGAACGTAGGGAAATCCACTATTTTTAATAGAATTGTTGGAGAAAG
AATTTCTATTGTTGAAGATATTCCGGGAGTAACACGAGATCGTATTTATAGTGCCGGAGAATGGTTAAATCATGAATTTA
ACATTATTGATACAGGTGGAATTGATATTGGAGACGAGCCATTTTTGACACAAATTCGTCAACAAGCAGAAGTAGCGATT
GACGAAGCGGACGTTATCATTTTTATGACAAATGGCCGCGACGGTGTAACGGCAGCTGATGAGGAAGTAGCGAAAATTTT
ATACCGCTCTAATAAACCTGTTGTACTTGCGGTAAATAAAGTAGATAATCCAGAGATGCGCAATGAAATTTATGACTTTT
ATGCATTAGGATTTGGAGAGCCGTTCCCAATTTCAGGTACACATGGGTTAGGGCTAGGGGATTTACTTGATGAAGTAGCG
CAGCATTTTCCTAAAGTAGAGGAAGAAGAATATGATGATGAAACGATCCGTTTCTGTCTCATTGGTCGTCCAAATGTAGG
GAAATCATCACTTGTCAATGCGCTTCTTGGTCAAGAACGTGTTATTGTAAGTAATGTGGCAGGAACAACGCGTGATGCTG
TCGATACGCCATATACGAAAGATGGCCAAGATTATGTCATTATTGATACAGCTGGAATGCGTAAAAAAGGGAAAGTGTAT
GAGAGTACCGAAAAGTATAGTGTACTTCGTGCATTACGAGCAATTGAACGCTCTGATGTTGTCTTAGTCGTATTAGACGG
CGAAGAAGGAATTATTGAACAAGATAAAAAGATTGCTGGATATGCGCATGATTCAGGACGAGCTGTTGTGATCGTTGTGA
ACAAGTGGGATGCAGTGAAAAAAGATGAGAAGACAATGAAGGCGTTTGAAGATAATATTCGTGCTCATTTCCAATTCTTA
GATTACGCTCCGATTGTATTTTTATCTGCAAAAACGAAAAAGCGTACGCAAACATTGCTGCCAGTTATTAATCAGGTGAG
CGAGAGCCATAACATCCGTGTACAAACGAATGTATTAAATGATGTCATTATGGATGCGGTAGCGATGAACCCAACGCCAA
CACATAACGGTAGCCGATTGAAAATTTTCTATGCAACACAAGTAGCGGTGAAACCACCAACATTTGTTGTGTTTGTAAAT
GATCCAGAATTAATGCACTTTTCATATGAGCGTTTCTTGAAGAACCGTCTTCGCGAATCGTTCGGATTTGTAGGAACGCC
AATTCGAATTATTGCTAGAGCAAGAGACTAA

Upstream 100 bases:

>100_bases
TTTTGATATAATGAGAAATATTCTGGAATGCAAATCCCTTCTTGCACAAAGAAGGGTTTTTTACATAATAAACAGAAGCA
AGTTGAAAGGATGAGAGCAT

Downstream 100 bases:

>100_bases
TGGAGAGGATGTGATTTTATGACAAAAATCACAGTAATAGGAGCAGGTAGCTGGGGGACAGCGTTAGCGATGGTATTAGC
TGACAATGGTCATGATGTAC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MPKPVVAIVGRPNVGKSTIFNRIVGERISIVEDIPGVTRDRIYSAGEWLNHEFNIIDTGGIDIGDEPFLTQIRQQAEVAI
DEADVIIFMTNGRDGVTAADEEVAKILYRSNKPVVLAVNKVDNPEMRNEIYDFYALGFGEPFPISGTHGLGLGDLLDEVA
QHFPKVEEEEYDDETIRFCLIGRPNVGKSSLVNALLGQERVIVSNVAGTTRDAVDTPYTKDGQDYVIIDTAGMRKKGKVY
ESTEKYSVLRALRAIERSDVVLVVLDGEEGIIEQDKKIAGYAHDSGRAVVIVVNKWDAVKKDEKTMKAFEDNIRAHFQFL
DYAPIVFLSAKTKKRTQTLLPVINQVSESHNIRVQTNVLNDVIMDAVAMNPTPTHNGSRLKIFYATQVAVKPPTFVVFVN
DPELMHFSYERFLKNRLRESFGFVGTPIRIIARARD

Sequences:

>Translated_436_residues
MPKPVVAIVGRPNVGKSTIFNRIVGERISIVEDIPGVTRDRIYSAGEWLNHEFNIIDTGGIDIGDEPFLTQIRQQAEVAI
DEADVIIFMTNGRDGVTAADEEVAKILYRSNKPVVLAVNKVDNPEMRNEIYDFYALGFGEPFPISGTHGLGLGDLLDEVA
QHFPKVEEEEYDDETIRFCLIGRPNVGKSSLVNALLGQERVIVSNVAGTTRDAVDTPYTKDGQDYVIIDTAGMRKKGKVY
ESTEKYSVLRALRAIERSDVVLVVLDGEEGIIEQDKKIAGYAHDSGRAVVIVVNKWDAVKKDEKTMKAFEDNIRAHFQFL
DYAPIVFLSAKTKKRTQTLLPVINQVSESHNIRVQTNVLNDVIMDAVAMNPTPTHNGSRLKIFYATQVAVKPPTFVVFVN
DPELMHFSYERFLKNRLRESFGFVGTPIRIIARARD
>Mature_435_residues
PKPVVAIVGRPNVGKSTIFNRIVGERISIVEDIPGVTRDRIYSAGEWLNHEFNIIDTGGIDIGDEPFLTQIRQQAEVAID
EADVIIFMTNGRDGVTAADEEVAKILYRSNKPVVLAVNKVDNPEMRNEIYDFYALGFGEPFPISGTHGLGLGDLLDEVAQ
HFPKVEEEEYDDETIRFCLIGRPNVGKSSLVNALLGQERVIVSNVAGTTRDAVDTPYTKDGQDYVIIDTAGMRKKGKVYE
STEKYSVLRALRAIERSDVVLVVLDGEEGIIEQDKKIAGYAHDSGRAVVIVVNKWDAVKKDEKTMKAFEDNIRAHFQFLD
YAPIVFLSAKTKKRTQTLLPVINQVSESHNIRVQTNVLNDVIMDAVAMNPTPTHNGSRLKIFYATQVAVKPPTFVVFVND
PELMHFSYERFLKNRLRESFGFVGTPIRIIARARD

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=457, Percent_Identity=40.0437636761488, Blast_Score=336, Evalue=2e-93,
Organism=Escherichia coli, GI1788919, Length=186, Percent_Identity=32.7956989247312, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI2367268, Length=94, Percent_Identity=44.6808510638298, Blast_Score=79, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6323665, Length=202, Percent_Identity=33.1683168316832, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45550813, Length=191, Percent_Identity=30.8900523560209, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48755; Mature: 48624

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKPVVAIVGRPNVGKSTIFNRIVGERISIVEDIPGVTRDRIYSAGEWLNHEFNIIDTGG
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCHHHCCCEEEEEECCC
IDIGDEPFLTQIRQQAEVAIDEADVIIFMTNGRDGVTAADEEVAKILYRSNKPVVLAVNK
CCCCCCHHHHHHHHHHHHEECCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEEC
VDNPEMRNEIYDFYALGFGEPFPISGTHGLGLGDLLDEVAQHFPKVEEEEYDDETIRFCL
CCCHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
IGRPNVGKSSLVNALLGQERVIVSNVAGTTRDAVDTPYTKDGQDYVIIDTAGMRKKGKVY
ECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCH
ESTEKYSVLRALRAIERSDVVLVVLDGEEGIIEQDKKIAGYAHDSGRAVVIVVNKWDAVK
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHCCCCCEEEEECCCCEEEEEEECCCCCC
KDEKTMKAFEDNIRAHFQFLDYAPIVFLSAKTKKRTQTLLPVINQVSESHNIRVQTNVLN
HHHHHHHHHHHHHHHEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEHHHHH
DVIMDAVAMNPTPTHNGSRLKIFYATQVAVKPPTFVVFVNDPELMHFSYERFLKNRLRES
HHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHH
FGFVGTPIRIIARARD
HCCCCCCCEEEEECCC
>Mature Secondary Structure 
PKPVVAIVGRPNVGKSTIFNRIVGERISIVEDIPGVTRDRIYSAGEWLNHEFNIIDTGG
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCHHHCCCEEEEEECCC
IDIGDEPFLTQIRQQAEVAIDEADVIIFMTNGRDGVTAADEEVAKILYRSNKPVVLAVNK
CCCCCCHHHHHHHHHHHHEECCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEEC
VDNPEMRNEIYDFYALGFGEPFPISGTHGLGLGDLLDEVAQHFPKVEEEEYDDETIRFCL
CCCHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
IGRPNVGKSSLVNALLGQERVIVSNVAGTTRDAVDTPYTKDGQDYVIIDTAGMRKKGKVY
ECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCH
ESTEKYSVLRALRAIERSDVVLVVLDGEEGIIEQDKKIAGYAHDSGRAVVIVVNKWDAVK
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHCCCCCEEEEECCCCEEEEEEECCCCCC
KDEKTMKAFEDNIRAHFQFLDYAPIVFLSAKTKKRTQTLLPVINQVSESHNIRVQTNVLN
HHHHHHHHHHHHHHHEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEHHHHH
DVIMDAVAMNPTPTHNGSRLKIFYATQVAVKPPTFVVFVNDPELMHFSYERFLKNRLRES
HHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHH
FGFVGTPIRIIARARD
HCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA