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The map label for this gene is sirC [H]

Identifier: 152974953

GI number: 152974953

Start: 1260285

End: 1260902

Strand: Direct

Name: sirC [H]

Synonym: Bcer98_1150

Alternate gene names: 152974953

Gene position: 1260285-1260902 (Clockwise)

Preceding gene: 152974952

Following gene: 152974954

Centisome position: 30.84

GC content: 36.57

Gene sequence:

>618_bases
ATGTATCCACTTACAGTTCGAATTGAAAATAAGCGCGTTGTTGTTATTGGGGGCGGGAAGGTTGCTGGATTTAAAATTAT
ACCGCTATTAAACCAAGGAGCAAATATTATTGTTGTGAGTCCTAAATTAGATGCAAGCTTAGTGAAACTTGTCGAATCGA
AAAAAATCCGCTGGTATCAAAAAGAGTATGAAAATGGCGATTTAGAAGGGGCTTTTTTAGTAGTGGCAGCCACTAGCGAT
CCGTTCTTAAATGAAAGAATTGAAAAGGATGCTGGGACAAATCAATTGGTAAATGTGATTACAAATCCAGAAAAGGGAAA
CGTTCATTTTCCATCTACCATTCATCGTGGCAAGCTTAATATAGCTGTTTCTACAGGAGGAGCAAGTCCGAAGCTTGCGA
AGAAAATTCGCGATGAAATTGCGCATAAATACGGTGAGATCTATGAAACATATCTCGAGTTTCTATATGAAGTAAGAAGA
AAAGTGAAAGAATTACAATTGGAAAAACGGGAGCAAAATAGAATGCTACAAGAAGTGCTAAAGCCTATATACCTTCAAAA
AGAAACAGAACGAGAATTATTTTTACAAGCATTAGAGAAAAAGAGTCAAGTAGGATAG

Upstream 100 bases:

>100_bases
CAAAATGCGGATATACATATAAGTCCGTACTTAGGAAAGAATCCTACAGTTCGAAATATGCTAATTCAAAAGACAGAACG
GCTATTAAGGAGCGATCAAT

Downstream 100 bases:

>100_bases
AACATGAATCGTACTTTACAAACAGAATCGTATGATTTATAATCACAAGTATCTTTAAAATATGAAATCGATGAGCAAGA
AGAGTATGTATATTTGAGGC

Product: precorrin-2 dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MYPLTVRIENKRVVVIGGGKVAGFKIIPLLNQGANIIVVSPKLDASLVKLVESKKIRWYQKEYENGDLEGAFLVVAATSD
PFLNERIEKDAGTNQLVNVITNPEKGNVHFPSTIHRGKLNIAVSTGGASPKLAKKIRDEIAHKYGEIYETYLEFLYEVRR
KVKELQLEKREQNRMLQEVLKPIYLQKETERELFLQALEKKSQVG

Sequences:

>Translated_205_residues
MYPLTVRIENKRVVVIGGGKVAGFKIIPLLNQGANIIVVSPKLDASLVKLVESKKIRWYQKEYENGDLEGAFLVVAATSD
PFLNERIEKDAGTNQLVNVITNPEKGNVHFPSTIHRGKLNIAVSTGGASPKLAKKIRDEIAHKYGEIYETYLEFLYEVRR
KVKELQLEKREQNRMLQEVLKPIYLQKETERELFLQALEKKSQVG
>Mature_205_residues
MYPLTVRIENKRVVVIGGGKVAGFKIIPLLNQGANIIVVSPKLDASLVKLVESKKIRWYQKEYENGDLEGAFLVVAATSD
PFLNERIEKDAGTNQLVNVITNPEKGNVHFPSTIHRGKLNIAVSTGGASPKLAKKIRDEIAHKYGEIYETYLEFLYEVRR
KVKELQLEKREQNRMLQEVLKPIYLQKETERELFLQALEKKSQVG

Specific function: Catalyzes the dehydrogenation of precorrin-2 to form sirohydrochlorin used as precursor in both siroheme biosynthesis and in the anaerobic branch of adenosylcobalamin biosynthesis [H]

COG id: COG1648

COG function: function code H; Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789768, Length=139, Percent_Identity=28.7769784172662, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR006367 [H]

Pfam domain/function: NA

EC number: =1.3.1.76 [H]

Molecular weight: Translated: 23304; Mature: 23304

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPLTVRIENKRVVVIGGGKVAGFKIIPLLNQGANIIVVSPKLDASLVKLVESKKIRWYQ
CCEEEEEECCCEEEEEECCEEECEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHH
KEYENGDLEGAFLVVAATSDPFLNERIEKDAGTNQLVNVITNPEKGNVHFPSTIHRGKLN
HHCCCCCCCEEEEEEEECCCCHHHHHHHHCCCCCHHHHHHCCCCCCCEECCCCCCCCEEE
IAVSTGGASPKLAKKIRDEIAHKYGEIYETYLEFLYEVRRKVKELQLEKREQNRMLQEVL
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KPIYLQKETERELFLQALEKKSQVG
HHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYPLTVRIENKRVVVIGGGKVAGFKIIPLLNQGANIIVVSPKLDASLVKLVESKKIRWYQ
CCEEEEEECCCEEEEEECCEEECEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHH
KEYENGDLEGAFLVVAATSDPFLNERIEKDAGTNQLVNVITNPEKGNVHFPSTIHRGKLN
HHCCCCCCCEEEEEEEECCCCHHHHHHHHCCCCCHHHHHHCCCCCCCEECCCCCCCCEEE
IAVSTGGASPKLAKKIRDEIAHKYGEIYETYLEFLYEVRRKVKELQLEKREQNRMLQEVL
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KPIYLQKETERELFLQALEKKSQVG
HHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA