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The map label for this gene is sirB [H]

Identifier: 152974952

GI number: 152974952

Start: 1259558

End: 1260310

Strand: Direct

Name: sirB [H]

Synonym: Bcer98_1149

Alternate gene names: 152974952

Gene position: 1259558-1260310 (Clockwise)

Preceding gene: 152974951

Following gene: 152974953

Centisome position: 30.82

GC content: 34.0

Gene sequence:

>753_bases
ATGAAAGCAGTGCTGTATATATGTCATGGAAGTAGATTAAAAGCTGCGAAAGAAGAGGCGATACAGTTCGTTACTTCTTG
TATGAGTCACATTCATGCGTCTGTTCAAGAAGTTTGCTTTTTAGAGTTGGCAAGTCCATCCATTGAAGAGGGAATTGCTG
CTTGTATAAAAAGAGGAGCAACAAAAATTATTGTCATACCAGTTTTTCTATTAGCAGCAGGACATGTAAAAAAAGATATT
CCATATGAATTACAAAAAATAAAAAATAAATATGAGAATCTTGAAATTGTATATGGTGATGCATTTGGAGTATCTGATTC
GCTTATTTTAGCCGCTTATAAAGAAAGTGGTTTGGAAGAATATCAGGAAGAAGCAACGCTTTTACTAGTAGCAAGGGGAA
GTAGTGAGCCAGAAATAGTAGAGAATATGAGGGAGATTGCGTTTTTATTTCAGCAGCAGAAGAATGTGAAAACGGTGGAA
GTATGCTATTTAGCTGCAACAGAGCCAAGATTTGAAGATAAATTACAAGAAATAATAGAAAGAAAAGAAAAGCATATCGT
CGTTTTGCCTTATTTATTATTTACAGGACTGTTAATGAAACATATTGAACAAGAAGTAAGTAAATATCAAAATGCGGATA
TACATATAAGTCCGTACTTAGGAAAGAATCCTACAGTTCGAAATATGCTAATTCAAAAGACAGAACGGCTATTAAGGAGC
GATCAATATGTATCCACTTACAGTTCGAATTGA

Upstream 100 bases:

>100_bases
AGTATGATTGTCATTGGAGAAGTCGTTCGTTTTAGGGAAAAGATTCACTGGTTTGAACAGCAAACAGAAGTAGCATATTC
AGTAAGCGGAGTATTGTAAA

Downstream 100 bases:

>100_bases
AAATAAGCGCGTTGTTGTTATTGGGGGCGGGAAGGTTGCTGGATTTAAAATTATACCGCTATTAAACCAAGGAGCAAATA
TTATTGTTGTGAGTCCTAAA

Product: cobalamin (vitamin B12) biosynthesis CbiX protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MKAVLYICHGSRLKAAKEEAIQFVTSCMSHIHASVQEVCFLELASPSIEEGIAACIKRGATKIIVIPVFLLAAGHVKKDI
PYELQKIKNKYENLEIVYGDAFGVSDSLILAAYKESGLEEYQEEATLLLVARGSSEPEIVENMREIAFLFQQQKNVKTVE
VCYLAATEPRFEDKLQEIIERKEKHIVVLPYLLFTGLLMKHIEQEVSKYQNADIHISPYLGKNPTVRNMLIQKTERLLRS
DQYVSTYSSN

Sequences:

>Translated_250_residues
MKAVLYICHGSRLKAAKEEAIQFVTSCMSHIHASVQEVCFLELASPSIEEGIAACIKRGATKIIVIPVFLLAAGHVKKDI
PYELQKIKNKYENLEIVYGDAFGVSDSLILAAYKESGLEEYQEEATLLLVARGSSEPEIVENMREIAFLFQQQKNVKTVE
VCYLAATEPRFEDKLQEIIERKEKHIVVLPYLLFTGLLMKHIEQEVSKYQNADIHISPYLGKNPTVRNMLIQKTERLLRS
DQYVSTYSSN
>Mature_250_residues
MKAVLYICHGSRLKAAKEEAIQFVTSCMSHIHASVQEVCFLELASPSIEEGIAACIKRGATKIIVIPVFLLAAGHVKKDI
PYELQKIKNKYENLEIVYGDAFGVSDSLILAAYKESGLEEYQEEATLLLVARGSSEPEIVENMREIAFLFQQQKNVKTVE
VCYLAATEPRFEDKLQEIIERKEKHIVVLPYLLFTGLLMKHIEQEVSKYQNADIHISPYLGKNPTVRNMLIQKTERLLRS
DQYVSTYSSN

Specific function: Chelates iron to the siroheme precursor [H]

COG id: COG2138

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiX family. SirB subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002762 [H]

Pfam domain/function: PF01903 CbiX [H]

EC number: =4.99.1.4 [H]

Molecular weight: Translated: 28356; Mature: 28356

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVLYICHGSRLKAAKEEAIQFVTSCMSHIHASVQEVCFLELASPSIEEGIAACIKRGA
CCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
TKIIVIPVFLLAAGHVKKDIPYELQKIKNKYENLEIVYGDAFGVSDSLILAAYKESGLEE
CEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHH
YQEEATLLLVARGSSEPEIVENMREIAFLFQQQKNVKTVEVCYLAATEPRFEDKLQEIIE
HHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHH
RKEKHIVVLPYLLFTGLLMKHIEQEVSKYQNADIHISPYLGKNPTVRNMLIQKTERLLRS
HHHCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHC
DQYVSTYSSN
CCHHHHCCCC
>Mature Secondary Structure
MKAVLYICHGSRLKAAKEEAIQFVTSCMSHIHASVQEVCFLELASPSIEEGIAACIKRGA
CCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
TKIIVIPVFLLAAGHVKKDIPYELQKIKNKYENLEIVYGDAFGVSDSLILAAYKESGLEE
CEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHH
YQEEATLLLVARGSSEPEIVENMREIAFLFQQQKNVKTVEVCYLAATEPRFEDKLQEIIE
HHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHH
RKEKHIVVLPYLLFTGLLMKHIEQEVSKYQNADIHISPYLGKNPTVRNMLIQKTERLLRS
HHHCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHC
DQYVSTYSSN
CCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA